chlorpromazine has been researched along with Injury, Myocardial Reperfusion in 3 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Combination of chlorpromazine (CPZ) and verapamil (Ver) was found to decrease the incidence of ventricular arrhythmias and ventricular fibrillation induced by myocardial ischemia and reperfusion, lower serum creatine phosphokinase (CPK) and decrease the content of malondialdehyde (MDA) in heart tissue homogenate especially in mitochondria; and increase the phospholipid content and the phospholipid/cholesterol ratio; and decrease the myocardial "cell calcium" content in the reperfused area." | 3.68 | [Protective effects of combination of chlorpromazine and verapamil on ischemia-reperfusion induced injury in rat myocardium]. ( Deng, Y; Zhang, ZS, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Deng, Y | 1 |
| Zhang, ZS | 1 |
| Katsuoka, M | 1 |
| Ohnishi, ST | 1 |
| Slezák, J | 1 |
| Tribulová, N | 1 |
| Ziegelhöffer, A | 1 |
| Gabauer, I | 1 |
| Styk, J | 1 |
| Holec, V | 1 |
3 other studies available for chlorpromazine and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
[Protective effects of combination of chlorpromazine and verapamil on ischemia-reperfusion induced injury in rat myocardium].
Topics: Animals; Chlorpromazine; Drug Therapy, Combination; Female; Male; Mitochondria, Heart; Myocardial Re | 1993 |
Pharmacologic protection of perfused rat heart against global ischemia.
Topics: Animals; Chlorpromazine; Coronary Disease; Egtazic Acid; Free Radicals; Heart; In Vitro Techniques; | 1989 |
[Protection of myocytes against reperfusion injury by calmodulin inhibition].
Topics: Animals; Calmodulin; Chlorpromazine; Dogs; Myocardial Reperfusion Injury; Myocardium; Trifluoperazin | 1989 |