chlorpromazine has been researched along with Infarction, Middle Cerebral Artery in 2 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Infarction, Middle Cerebral Artery: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present study determined whether neuroprotective PH with chlorpromazine and promethazine (C + P), plus dihydrocapsaicin (DHC) improved glucose metabolism in acute ischemic stroke." | 4.12 | Neuroprotective Effects of Pharmacological Hypothermia on Hyperglycolysis and Gluconeogenesis in Rats after Ischemic Stroke. ( Ding, Y; Du, H; Geng, X; Guan, L; Ji, Y; Lee, H; Li, F; Peng, C; Shen, J, 2022) |
| "Chlorpromazine (CPZ) is a well-known antipsychotic drug, still widely being used to treat symptoms of schizophrenia, psychotic depression and organic psychoses." | 1.40 | Chlorpromazine confers neuroprotection against brain ischemia by activating BKCa channel. ( Han, F; Li, HJ; Qi, Z; Wang, MY; Xue, MQ; Zhang, YJ; Zhou, L, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guan, L | 1 |
| Lee, H | 1 |
| Geng, X | 1 |
| Li, F | 1 |
| Shen, J | 1 |
| Ji, Y | 1 |
| Peng, C | 1 |
| Du, H | 1 |
| Ding, Y | 1 |
| Li, HJ | 1 |
| Zhang, YJ | 1 |
| Zhou, L | 1 |
| Han, F | 1 |
| Wang, MY | 1 |
| Xue, MQ | 1 |
| Qi, Z | 1 |
2 other studies available for chlorpromazine and Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
Neuroprotective Effects of Pharmacological Hypothermia on Hyperglycolysis and Gluconeogenesis in Rats after Ischemic Stroke.
Topics: Adenosine Triphosphate; Animals; Chlorpromazine; Gluconeogenesis; Glucose; Hypothermia; Infarction, | 2022 |
Chlorpromazine confers neuroprotection against brain ischemia by activating BKCa channel.
Topics: Animals; Brain; Chlorpromazine; In Vitro Techniques; Infarction, Middle Cerebral Artery; Large-Condu | 2014 |