chlorpromazine has been researched along with Incontinentia Pigmenti Achromians in 68 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Melanosis observed in association with prolonged chlorpromazine therapy has become a serious problem in mental institutions." | 7.64 | THERAPY OF CHLORPROMAZINE MELANOSIS: A PRELIMINARY REPORT. ( BAKER, RA; GREINER, AC; NICOLSON, GA, 1964) |
| "Melanosis observed in association with prolonged chlorpromazine therapy has become a serious problem in mental institutions." | 3.64 | THERAPY OF CHLORPROMAZINE MELANOSIS: A PRELIMINARY REPORT. ( BAKER, RA; GREINER, AC; NICOLSON, GA, 1964) |
| "Chlorpromazine is known to cause abnormal oculocutaneous pigmentation in sun-exposed areas." | 1.40 | Chlorpromazine-induced skin pigmentation with corneal and lens opacities. ( Dunnick, CA; Huff, LS; Lucas, LM; Pederson, JF; Prado, R, 2014) |
| " Chlorpromazine therapy in a cumulative dosage exceeding 1,100 g resulted in dramatic skin discoloration and multiple crystalline deposits in both corneas." | 1.31 | Corneal deposition after high-dose chlorpromazine hydrochloride therapy. ( Domniz, Y; Lawless, MA; Rogers, CM; Sutton, GL; Webber, SK, 2001) |
| "A 57-year-old schizoaffective disorder patient was placed on chlorpromazine because of its sedative properties and low profile for extrapyramidal side effects." | 1.29 | Cutaneous and ocular changes associated with the use of chlorpromazine. ( Berk, MA; Mosnaim, AD; Richer, S; Wolf, ME, 1993) |
| " While the mean age and mean duration of hospitalization in the skin-pigmented population was slightly higher and larger than in the total population of our survey, no definitive relationships between sex, diagnosis, drugs and dosage of medication were revealed." | 1.27 | Neuroleptic-induced skin pigmentation in chronic hospitalized schizophrenic patients. ( Ban, TA; Guy, W; Wilson, WH, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 60 (88.24) | 18.7374 |
| 1990's | 3 (4.41) | 18.2507 |
| 2000's | 3 (4.41) | 29.6817 |
| 2010's | 2 (2.94) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huff, LS | 1 |
| Prado, R | 1 |
| Pederson, JF | 1 |
| Dunnick, CA | 1 |
| Lucas, LM | 1 |
| Gupta, A | 1 |
| Agarwal, A | 1 |
| Ram, J | 1 |
| ZELICKSON, AS | 3 |
| ZELLER, HC | 1 |
| GREINER, AC | 5 |
| BERRY, K | 2 |
| SULMAN, FG | 1 |
| PERRY, TL | 1 |
| CULLING, CF | 1 |
| HANSEN, S | 1 |
| FELDMAN, PE | 1 |
| FRIERSON, BD | 1 |
| HAYS, GB | 1 |
| LYLE, CB | 1 |
| WHEELER, CE | 1 |
| NICOLSON, GA | 3 |
| BAKER, RA | 1 |
| CORMIA, FE | 1 |
| MASSEY, LW | 1 |
| CAIRNS, RJ | 1 |
| CAPOORE, HS | 1 |
| GREGORY, ID | 1 |
| LINGJAERDE, O | 1 |
| TREDICI, LM | 2 |
| SCHIELE, BC | 1 |
| MCCLANAHAN, WS | 2 |
| BAN, TA | 3 |
| LEHMANN, HE | 3 |
| WETTERHOLM, DH | 1 |
| SNOW, HL | 1 |
| WINTER, FC | 1 |
| BARSA, JA | 1 |
| NEWTON, JC | 1 |
| SAUNDERS, JC | 1 |
| NAHUM, LH | 1 |
| GALLAI, Z | 1 |
| WARNES, H | 1 |
| LEE, H | 1 |
| Bain, S | 1 |
| Hamburger, J | 1 |
| Bolt, AG | 2 |
| Forrest, IS | 5 |
| Pilger, IS | 1 |
| Bloom, D | 2 |
| Krishnan, B | 2 |
| Thavundayil, JX | 1 |
| Lal, S | 5 |
| Silver, B | 1 |
| Desjardins, B | 1 |
| Thavundayil, J | 1 |
| Thompson, T | 1 |
| Wolf, ME | 1 |
| Richer, S | 1 |
| Berk, MA | 1 |
| Mosnaim, AD | 1 |
| Webber, SK | 1 |
| Domniz, Y | 1 |
| Sutton, GL | 1 |
| Rogers, CM | 1 |
| Lawless, MA | 1 |
| Haddad, RI | 1 |
| Guy, W | 1 |
| Wilson, WH | 1 |
| Thompson, TR | 1 |
| Yassa, R | 1 |
| Gerstein, W | 1 |
| Thaler, JS | 1 |
| Curinga, R | 1 |
| Kiracofe, G | 1 |
| Levantine, A | 1 |
| Almeyda, J | 1 |
| Green, DE | 1 |
| Siddall, JR | 4 |
| Appleton, WS | 1 |
| Shader, RI | 1 |
| DiMascio, A | 1 |
| Gol'dovskaia, IL | 2 |
| Petrohelos, MA | 2 |
| Tricoulis, D | 2 |
| Baron, JB | 1 |
| Rivoalan, Y | 1 |
| Morel, P | 1 |
| Mathalone, MB | 2 |
| Boet, DJ | 1 |
| Jung, EG | 1 |
| Kosek, JC | 2 |
| Aber, RC | 2 |
| Serra, MT | 3 |
| Clark, ML | 1 |
| Serafetinides, EA | 1 |
| Wise, JB | 1 |
| Colmore, JP | 1 |
| Van Woert, MH | 1 |
| Roos, BE | 1 |
| Harris, JE | 1 |
| Knobloch, WH | 1 |
| Udasco, RL | 1 |
| Gibbard, BA | 1 |
| Barnes, GJ | 1 |
| Cameron, ME | 1 |
| Dencker, SJ | 1 |
| Enoksson, P | 1 |
| Edler, K | 1 |
| Hashimoto, K | 1 |
| Wiener, W | 1 |
| Albert, J | 1 |
| Nelson, RG | 1 |
| Gunby, B | 1 |
| Sandvig, K | 1 |
| Steenfeldt-Foss, OW | 1 |
| Simpson, GM | 1 |
| Amuso, D | 1 |
4 reviews available for chlorpromazine and Incontinentia Pigmenti Achromians
| Article | Year |
|---|---|
Drug induced changes in pigmentation.
Topics: Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Antimalarials; Arsenic; Bismuth; Bleomycin; B | 1973 |
Ocular complications related to phenothiazines.
Topics: Chlorpromazine; Eye Diseases; Eyelids; Female; Humans; Male; Mydriatics; Phenothiazines; Pigmentatio | 1968 |
Ocular (pigmentary) effects of psychotropic drugs.
Topics: Cataract; Chlorpromazine; Corneal Opacity; Humans; Phenothiazines; Pigmentation Disorders; Tranquili | 1970 |
[Complications on the part of the eyes during employment of psychotropic drugs (review of the foreign literature)].
Topics: Chlorpromazine; Corneal Opacity; Eye Diseases; Female; Humans; Lens, Crystalline; Male; Methotrimepr | 1969 |
2 trials available for chlorpromazine and Incontinentia Pigmenti Achromians
| Article | Year |
|---|---|
[False-positive ocular pigmentation during administration of neuroleptics].
Topics: Chlorpromazine; Clinical Trials as Topic; Corneal Opacity; Diagnostic Errors; Humans; Pigmentation D | 1971 |
Ocular pigment deposits: drug-induced false-positives.
Topics: Butyrophenones; Chlorpromazine; Humans; Lens, Crystalline; Pigmentation Disorders; Pigments, Biologi | 1970 |
62 other studies available for chlorpromazine and Incontinentia Pigmenti Achromians
| Article | Year |
|---|---|
Chlorpromazine-induced skin pigmentation with corneal and lens opacities.
Topics: Antipsychotic Agents; Chlorpromazine; Cornea; Corneal Opacity; Female; Humans; Pigmentation Disorder | 2014 |
Reversal of toxic manifestations of chlorpromazine.
Topics: Chlorpromazine; Corneal Diseases; Dopamine Antagonists; Eye; Humans; Lens Diseases; Male; Pigmentati | 2014 |
A NEW AND UNUSUAL REACTION TO CHLORPROMAZINE.
Topics: Chlorpromazine; Pathology; Photosensitivity Disorders; Pigmentation Disorders; Schizophrenia; Toxico | 1964 |
SKIN PIGMENTATION AND CORNEAL AND LENS OPACITIES WITH PROLONGED CHLORPROMAZINE THERAPY.
Topics: Cataract; Chlorpromazine; Cornea; Corneal Opacity; Female; Humans; Lens, Crystalline; Melanins; Opht | 1964 |
SKIN PIGMENTATION FOLLOWING CHLORPROMAZINE TREATMENT.
Topics: Blood; Chlorpromazine; Chromatophores; Pigmentation Disorders; Pituitary Hormones; Pituitary Hormone | 1964 |
7-HYDROXYCHLORPROMAZINE: POTENTIAL TOXIC DRUG METABOLITE IN PSYCHIATRIC PATIENTS.
Topics: Body Fluids; Chlorpromazine; Humans; Lens, Crystalline; Liver; Melanins; Mental Disorders; Metabolis | 1964 |
DERMATOLOGICAL AND OPHTHALMOLOGICAL CHANGES ASSOCIATED WITH PROLONGED CHLORPROMAZINE THERAPY.
Topics: Chlorpromazine; Corneal Opacity; Female; Humans; Menstruation Disturbances; Pigmentation Disorders; | 1964 |
SLATE-GRAY COLOR IN PATIENTS RECEIVING CHLORPROMAZINE.
Topics: Argyria; Chlorpromazine; Chromatophores; Dermatitis, Phototoxic; Diagnosis, Differential; Drug Thera | 1964 |
PIGMENT DEPOSITION IN VISCERA ASSOCIATED WITH PROLONGED CHLORPROMAZINE THERAPY.
Topics: Adolescent; Autonomic Nervous System; Cerebral Cortex; Chlorpromazine; Cornea; Endocrine Glands; Epi | 1964 |
THERAPY OF CHLORPROMAZINE MELANOSIS: A PRELIMINARY REPORT.
Topics: Body Fluids; Chlorpromazine; Copper; Darkness; Drug Therapy; Eye Diseases; Histocytochemistry; Hospi | 1964 |
POTENTIATION OF HYPERPIGMENTATION FROM X-RADIATION. EFFECTS OF DEMETHYLCHLORTETRACYCLINE THERAPY.
Topics: Acne Vulgaris; Chlorpromazine; Demeclocycline; Drug Therapy; Erythromycin; Facial Dermatoses; Humans | 1964 |
SKIN PIGMENTATION, CORNEAL AND LENS OPACITIES WITH PROLONGED CHLORPROMAZINE TREATMENT.
Topics: Biopsy; Cataract; Chlorpromazine; Cornea; Corneal Opacity; Drug Therapy; Electrocardiography; Eye Di | 1965 |
OCULOCUTANEOUS CHANGES AFTER YEARS OF HIGH DOSES OF CHLORPROMAZINE.
Topics: Chlorpromazine; Diagnosis; Drug Eruptions; Eye Diseases; Facial Dermatoses; Pathology; Pigmentation | 1965 |
[LATE IRREVERSIBLE COMPLICATIONS OF CHLORPROMAZINE TREATMENT].
Topics: Chlorpromazine; Pigmentation Disorders; Skin Diseases; Toxicology | 1965 |
THE INCIDENCE AND MANAGEMENT OF CHLORPROMAZINE--SKIN-EYE SYNDROME.
Topics: Chlorpromazine; Drug Therapy; Eye Diseases; Incidence; Minnesota; Pigmentation Disorders; Syndrome; | 1965 |
NEW SIDE EFFECTS IN PROLONGED CHLORPROMAZINE THERAPY.
Topics: Chlorpromazine; Drug Therapy; Melanins; Melanosis; Mental Disorders; Metabolism; Pathology; Penicill | 1965 |
SKIN PIGMENTATION, A RARE SIDE EFFECT OF CHLORPROMAZINE.
Topics: Chemical Phenomena; Chemistry; Chlorpromazine; Diagnosis, Differential; Drug Therapy; Epilepsy; Eye | 1965 |
A CLINICAL STUDY OF PIGMENTARY CHANGE IN CORNEA AND LENS IN CHRONIC CHLORPROMAZINE THERAPY.
Topics: Amblyopia; Chlorpromazine; Cornea; Drug Therapy; Eye Diseases; Humans; Lens, Crystalline; Mental Dis | 1965 |
LENS AND CORENEA CHANGES DURING PHENOTHIAZINE THERAPY: A PRELIMINARY REPORT.
Topics: Chlorpromazine; Corneal Opacity; Drug Therapy; Eye Diseases; Fluphenazine; Lens, Crystalline; Mental | 1965 |
THE PURPLE-PEOPLE SYNDROME.
Topics: Chlorpromazine; Photosensitivity Disorders; Pigmentation Disorders; Syndrome; Toxicology | 1965 |
[RELATION BETWEEN PHOTOSENSITIVITY AND PATHOLOGIC PIGMENTATION OF THE SKIN WITH HIGH DOSES OF CHLORPROMAZINE].
Topics: Chlorpromazine; Dermatitis, Phototoxic; Drug Therapy; Photosensitivity Disorders; Pigmentation; Pigm | 1965 |
Physical signs for the General Dental Practitioner. Case 19. Pigmentation disorder.
Topics: Antipsychotic Agents; Chlorpromazine; Humans; Male; Mouth Mucosa; Pigmentation Disorders | 2004 |
Interaction between human melanoprotein and chlorpromazine derivatives. II. Spectrophotometric studies.
Topics: Chlorpromazine; Hair; Humans; Melanoma; Pigmentation Disorders; Proteins; Spectrophotometry | 1967 |
Pigmentation of the cornea: a review and classification.
Topics: Adult; Child; Chloroquine; Chlorpromazine; Corneal Diseases; Drug-Related Side Effects and Adverse R | 1983 |
Resolution of chlorpromazine-induced cutaneous pigmentation following substitution with levomepromazine or other neuroleptics.
Topics: Adult; Antipsychotic Agents; Chlorpromazine; Female; Humans; Male; Methotrimeprazine; Pigmentation D | 1993 |
Replacement of chlorpromazine with other neuroleptics: effect on abnormal skin pigmentation and ocular changes.
Topics: Adult; Antipsychotic Agents; Chlorpromazine; Cornea; Corneal Diseases; Female; Follow-Up Studies; Ha | 1993 |
Cutaneous and ocular changes associated with the use of chlorpromazine.
Topics: Carcinoma, Basal Cell; Chlorpromazine; Drug Eruptions; Eye Diseases; Humans; Male; Middle Aged; Mout | 1993 |
Chlorpromazine-induced cutaneous pigmentation--effect of replacement with clozapine.
Topics: Antipsychotic Agents; Chlorpromazine; Clozapine; Female; Humans; Middle Aged; Pigmentation Disorders | 2000 |
Corneal deposition after high-dose chlorpromazine hydrochloride therapy.
Topics: Antipsychotic Agents; Chlorpromazine; Cornea; Corneal Opacity; Humans; Male; Middle Aged; Pigmentati | 2001 |
Blue skin pigmentation and chlorpromazine.
Topics: Chlorpromazine; Color; Humans; Male; Middle Aged; Pigmentation Disorders | 1977 |
Neuroleptic-induced skin pigmentation in chronic hospitalized schizophrenic patients.
Topics: Adult; Age Factors; Antipsychotic Agents; Chlorpromazine; Drug Eruptions; Female; Humans; Male; Midd | 1985 |
Resolution of chlorpromazine-induced pigmentation with haloperidol substitution.
Topics: Adult; Chlorpromazine; Female; Haloperidol; Humans; Male; Middle Aged; Pigmentation Disorders; Schiz | 1988 |
Relation of graded ocular anterior chamber pigmentation to phenothiazine intake in schizophrenics--quantification procedures.
Topics: Anterior Chamber; Chlorpromazine; Cornea; Eye Diseases; Humans; Pigmentation Disorders; Schizophreni | 1985 |
Phenothiazines: metabolism and analytical detection.
Topics: Animals; Autopsy; Chlorpromazine; Dansyl Compounds; Humans; In Vitro Techniques; Phenothiazines; Pig | 1972 |
Ocular complications of chlorpromazine therapy.
Topics: Adolescent; Adult; Aged; Chlorpromazine; Cornea; Eye Diseases; Female; Glaucoma; Humans; Lens, Cryst | 1969 |
Ocular complications of chlorpromazine therapy.
Topics: Adolescent; Adult; Aged; Chlorpromazine; Eye Diseases; Female; Greece; Humans; Long-Term Care; Male; | 1969 |
Long term evolution of the side-effect lens opacities induced by chlorpromazine prolonged therapy.
Topics: Cataract; Chlorpromazine; Female; Humans; Mental Disorders; Middle Aged; Pigmentation Disorders; Ski | 1971 |
Ocular complications of phenothiazines.
Topics: Adult; Chlorpromazine; Conjunctiva; Cornea; Eye Diseases; Female; Fundus Oculi; Humans; Intraocular | 1966 |
[Ophthalmologic study of patients receiving psychotropic drugs].
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents; Bipolar Disorder; Cataract; Cerebrova | 1970 |
Toxic effects of phenothiazines on the eye.
Topics: Adult; Arsenic; Cataract; Chemical Phenomena; Chemistry; Chlorpromazine; Color Vision Defects; Conju | 1970 |
[In vitro studies on chlorpromazine photoallergy].
Topics: Absorption; Blood Proteins; Candida; Chemical Phenomena; Chemistry; Chlorpromazine; In Vitro Techniq | 1970 |
Schizophrenia and the pineal gland.
Topics: Adult; Chlorpromazine; Copper; Eye Manifestations; Female; Glucagon; Humans; Male; Melanosis; Middle | 1970 |
Rabbit as a model for chlorpromazine-induced hyperpigmentation of the skin.
Topics: Animals; Chlorpromazine; Disease Models, Animal; Pigmentation Disorders; Rabbits; Radiation Effects; | 1970 |
Phenothiazines in ophthalmology.
Topics: Cataract; Chlorpromazine; Chorioretinitis; Eye Diseases; Humans; Melanins; Microscopy; Phenothiazine | 1967 |
Ocular effects of phenothiazine derivatives and reversibility.
Topics: Accommodation, Ocular; Animals; Cats; Chlorpromazine; Cornea; Eye Diseases; Female; Fundus Oculi; Hu | 1968 |
Isolation of chlorpromazine pigments in man.
Topics: Centrifugation; Chemical and Drug Induced Liver Injury; Chlorpromazine; Female; Humans; Infrared Ray | 1968 |
Distribution of chlorpromazine metabolites in selected organs of psychiatric patients chronically dosed up to the time of death.
Topics: Adult; Chlorpromazine; Glucuronates; Humans; Kidney; Liver; Lung; Male; Mental Disorders; Middle Age | 1968 |
[Adverse effects of phenothiazines].
Topics: Agranulocytosis; Chlorpromazine; Eye Manifestations; Female; Humans; Hypnotics and Sedatives; Male; | 1968 |
An animal model for chlorpromazine-induced hyperpigmentation of the skin.
Topics: Animals; Chlorpromazine; Humans; Melanins; Models, Biological; Pigmentation Disorders; Rabbits; Skin | 1969 |
The ocular toxic findings with prolonged and high dosage chlorpromazine intake.
Topics: Adolescent; Adult; Aged; Cataract; Chlorpromazine; Eye Manifestations; Humans; Lacrimal Apparatus; M | 1965 |
Skin pigmentation and chlorpromazine.
Topics: Chlorpromazine; Chromatophores; Female; Humans; Lysosomes; Melanins; Microscopy, Electron; Pigmentat | 1965 |
Ocular manifestations of chronic phenothiazine derivative administration.
Topics: Chlorpromazine; Eye Manifestations; Humans; Mental Disorders; Phenothiazines; Pigmentation Disorders | 1966 |
Ocular toxic changes associated with chlorpromazine and thioridazine.
Topics: Adolescent; Adult; Aged; Cataract; Chlorpromazine; Eye; Female; Fundus Oculi; Gonioscopy; Humans; In | 1966 |
Therapy of Phenothiazine-produced skin pigmentation: a preliminary report.
Topics: Ascorbic Acid; Chlorpromazine; Female; Humans; Penicillamine; Pigmentation Disorders; Schizophrenia | 1966 |
Skin and eye changes associated with chlorpromazine therapy.
Topics: Chlorpromazine; Epilepsy; Eye Diseases; Female; Humans; Male; Mental Disorders; Pigmentation Disorde | 1966 |
Chlorpromazine purple people.
Topics: Adult; Chlorpromazine; Female; Humans; Male; Middle Aged; Pigmentation Disorders | 1966 |
Ocular changes produced by chlorpromazine.
Topics: Adult; Aged; Cataract; Chlorpromazine; Corneal Opacity; Female; Humans; Male; Middle Aged; Ophthalmo | 1966 |
Ocular changes associated with chlorpromazine therapy. A preliminary report.
Topics: Adult; Aged; Cataract; Chlorpromazine; Corneal Opacity; Female; Glaucoma; Humans; Male; Middle Aged; | 1966 |
Skin changes and chlorpromazine. Some hazards of long-term drug therapy.
Topics: Biopsy; Chlorpromazine; Humans; Melanins; Microscopy, Electron; Pigmentation Disorders; Radiation Ef | 1966 |
An electron microscopic study of chlorpromazine pigmentation.
Topics: Adult; Chlorpromazine; Female; Histocytochemistry; Humans; In Vitro Techniques; Lysosomes; Male; Mel | 1966 |
Late oculocutaneous complications in phenothiazine therapy.
Topics: Adult; Chlorpromazine; Corneal Opacity; Female; Humans; Lens, Crystalline; Male; Middle Aged; Phenot | 1966 |
Treatment of chronic schizophrenia with tri-iodothyronine.
Topics: Chlorpromazine; Humans; Pigmentation Disorders; Schizophrenia; Triiodothyronine | 1966 |