chlorpromazine has been researched along with Idiopathic Pulmonary Fibrosis in 1 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Idiopathic Pulmonary Fibrosis: A common interstitial lung disease of unknown etiology, usually occurring between 50-70 years of age. Clinically, it is characterized by an insidious onset of breathlessness with exertion and a nonproductive cough, leading to progressive DYSPNEA. Pathological features show scant interstitial inflammation, patchy collagen fibrosis, prominent fibroblast proliferation foci, and microscopic honeycomb change.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amiloride pretreatment remarkably reduced the cellular uptake of CNPs, suggesting that lung fibroblasts mainly utilize the macropinocytosis-dependent mechanism when interacted with collagen." | 1.46 | The effects of collagen-rich extracellular matrix on the intracellular delivery of glycol chitosan nanoparticles in human lung fibroblasts. ( Hergert, P; Im, J; Jeon, S; Kim, H; Kim, K; Nho, RS; Panyam, J; Yhee, JY; Yoon, HY, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yhee, JY | 1 |
| Yoon, HY | 1 |
| Kim, H | 1 |
| Jeon, S | 1 |
| Hergert, P | 1 |
| Im, J | 1 |
| Panyam, J | 1 |
| Kim, K | 1 |
| Nho, RS | 1 |
1 other study available for chlorpromazine and Idiopathic Pulmonary Fibrosis
| Article | Year |
|---|---|
The effects of collagen-rich extracellular matrix on the intracellular delivery of glycol chitosan nanoparticles in human lung fibroblasts.
Topics: Amiloride; Cells, Cultured; Chitosan; Chlorpromazine; Collagen Type I; Drug Carriers; Drug Delivery | 2017 |