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chlorpromazine and Idiopathic Parkinson Disease

chlorpromazine has been researched along with Idiopathic Parkinson Disease in 87 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Research Excerpts

ExcerptRelevanceReference
" The anti-tremor potency of the compounds was assessed from suppression of Tremorine-induced tremors in mice."7.64Relationship between anti-acetylcholine and anti-Tremorine activity in anti-parkinsonian and related drugs. ( AHMED, A; MARSHALL, PB, 1962)
" The anti-tremor potency of the compounds was assessed from suppression of Tremorine-induced tremors in mice."3.64Relationship between anti-acetylcholine and anti-Tremorine activity in anti-parkinsonian and related drugs. ( AHMED, A; MARSHALL, PB, 1962)
"However, the performances of Huntington's disease subjects appeared to be different when compared to the other two groups."2.69Kinematic analysis of the reach to grasp movement in Parkinson's and Huntington's disease subjects. ( Bonfiglioli, C; Castiello, U; De Berti, G; Nichelli, P; Nicoletti, R, 1998)
"(ii) The effect of schizophrenia is to increase MAE duration, and this is not due to some peripheral artefact."2.39The duration of the movement aftereffect as an index of psychiatric illness. ( Harris, J, 1994)
"While neurodegenerative diseases affect millions of patients worldwide, there are insufficient available therapeutics to halt or slow down the progression of these diseases."1.72Design, Synthesis, and Biological Evaluation of Potent 20S Proteasome Activators for the Potential Treatment of α-Synucleinopathies. ( Jones, CL; Staerz, SD; Tepe, JJ, 2022)
"In addition to the diagnosis of chronic pseudoakathisia, five patients (62."1.31Prevalence and characteristics of patients with pseudoakathisia. ( Christodoulou, GN; Havaki-Kontaxaki, BJ; Kontaxakis, VP, 2000)
"Levodopa-induced dyskinesias (LID) in Parkinson's disease (PD) may be classified into three main categories: "On" dyskinesias, diphasic dyskinesias (DD), and "off" periods."1.28Levodopa-induced dyskinesias in Parkinson's disease: clinical and pharmacological classification. ( Gershanik, O; Luquin, MR; Obeso, JA; Scipioni, O; Vaamonde, J, 1992)

Research

Studies (87)

TimeframeStudies, this research(%)All Research%
pre-199079 (90.80)18.7374
1990's4 (4.60)18.2507
2000's1 (1.15)29.6817
2010's2 (2.30)24.3611
2020's1 (1.15)2.80

Authors

AuthorsStudies
Staerz, SD1
Jones, CL1
Tepe, JJ1
Rukmangathen, R1
Yallamalli, IM1
Yalavarthi, PR1
Lv, H1
Yu, F1
Sha, C1
Huang, Y1
Lu, Y1
Zhang, L1
Zhai, R1
Wang, T1
Fu, F1
BALESTRIERI, A1
MONTANARI, M1
BERGOUIGNAN, M1
DE BOUCAUD, P1
FOURNIAL, P1
BENTE, D1
ITIL, T1
MEGGIO, B1
CATTANI, F1
HAASE, HJ3
MAY, RH1
VOEGELE, GE1
FREYHAN, FA4
SOMOGYI, I1
TASS, G1
NAHUNEK, K1
RYBAKOVA, V1
HASKOVEC, L1
KNAUF, HW1
LIT, AC1
CAHAN, RB1
PARRISH, DD1
GUGGENHEIM, P1
COHEN, L1
GOLDSCHMIDT, D1
AHMED, A1
MARSHALL, PB1
DI PERRI, R2
GIAQUINTO, S1
MERIAUX, J1
NAVARRANNE, P1
STRATAS, NE1
PHILLIPS, RD1
WALKER, PA1
SANDIFER, MG1
MANGHI, E1
FLUGEL, F1
POURSINES, Y1
ALLIEZ, J1
TOGA, M1
Sheppard, C1
Merlis, S1
Rajput, AH1
Rozdilsky, B1
Hornykiewicz, O1
Shannak, K1
Lee, T1
Seeman, P1
Barbosa, ER1
Marchiori, PE1
Scaff, M1
de Assis, JL1
Young, SN1
Gauthier, S1
Chouinard, G1
Anderson, GM1
Purdy, WC1
Atadzhanov, M1
Campbell, DJ1
Mendelsohn, FA1
Adam, WR1
Funder, JW1
Harris, J1
Gorchein, A1
Bonfiglioli, C1
De Berti, G1
Nichelli, P1
Nicoletti, R1
Castiello, U1
Havaki-Kontaxaki, BJ1
Kontaxakis, VP1
Christodoulou, GN1
Hebenstreit, G1
Nagatsu, T1
Kanamori, T1
Kato, T1
Iizuka, R1
Narabayashi, H1
Martin, IC1
Stadler, H1
Ciria, MG1
Bartholini, G2
Beasley, BA1
Ford, DH1
Duvoisin, RC2
Pakszys, W1
Paulson, GW1
Rizvi, CA1
Crane, GE1
Arushanian, EB2
Luquin, MR1
Scipioni, O1
Vaamonde, J1
Gershanik, O1
Obeso, JA1
Poirier, LJ1
Stern, J1
Mendell, J1
Clark, K1
Vogt, M1
Carlsson, A1
Van Loon, GR1
Bruck, H1
Gerstenbrand, F1
Gnad, H1
Gründig, E1
Prosenz, P1
Turunen, S1
Achté, KA1
Klawans, HL1
Jurna, I1
Nell, T1
Schreyer, I1
Sourkes, TL1
Pakkenberg, H1
Bottcher, J1
Proctor, P1
McGinness, J1
Corry, P1
McClelland, HA1
Blessed, G1
Bhate, S1
Ali, N1
Clarke, PA1
Kelly, JT1
Zimmermann, RL1
Abuzzahab, FS1
Schiele, BC1
Singh, P2
McDevitt, D1
Mackay, J2
Hadden, DR2
Thody, AJ1
Shuster, S1
Messiha, FS1
Turek, I1
Morrison, AB1
Webster, RA1
McDevitt, DG1
Ambani, LM1
Van Woert, MH1
Bowers, MB1
Marsden, CD1
Ganev, G1
Karamalakov, L1
Milenkov, K1
Ianachkova, M1
Sakhatchieva, L1
Kiuchukova, P1
Roĭlev, I1
Naumov, I1
Cheshmedzhiev, P1
Dochkov, Zh1
Brindle, GF1
Jones, AB1
Pare, CM2
Nicholson, WJ1
Price, K1
Stacey, RS1
Steg, G1
Roos, BE1
Blum, B1
Weizmann, H1
Simpson, GM1
Krasilowsky, D1
Kulcsar, IS1
Merskey, H1
Bruno, A1
Bruno, SC1
Chase, TN1
Schnur, JA1
Gordon, EK1
Tissot, R1
Culebras, A1
Ialdygina, AS1
Pervomaĭskiĭ, BIa1
Antropov, IuA1
Hader, M1
Puca, FM1
Oehme, P1
Schwarz, K1
Ekdawi, MY1
Fowke, R1

Reviews

11 reviews available for chlorpromazine and Idiopathic Parkinson Disease

ArticleYear
[Modeling parkinsonism (review)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1982, Volume: 82, Issue:3

    Topics: Aluminum; Animals; Carbachol; Cats; Caudate Nucleus; Chlorides; Chlorpromazine; Disease Models, Anim

1982
Is aldosterone secretion under dopaminergic control?
    Circulation research, 1981, Volume: 49, Issue:6

    Topics: Aldosterone; Bromocriptine; Chlorpromazine; Dopamine; Dopamine Antagonists; Edema; Humans; Levodopa;

1981
The duration of the movement aftereffect as an index of psychiatric illness.
    Perception, 1994, Volume: 23, Issue:10

    Topics: Adult; Antiparkinson Agents; Attention; Chlorpromazine; Dopamine; Eye Movements; Female; Fixation, O

1994
[The use of psychotropic drugs in general practice].
    Wiener medizinische Wochenschrift (1946), 1977, Oct-10, Volume: 127, Issue:18

    Topics: Alcohol Withdrawal Delirium; Anti-Anxiety Agents; Anxiety; Benzhydryl Compounds; Benzodiazepines; Bi

1977
Aging and the extrapyramidal system.
    The Medical clinics of North America, 1976, Volume: 60, Issue:6

    Topics: Aged; Aging; Basal Ganglia Diseases; Chlorpromazine; Chorea; Dopamine; Frontal Lobe; Gait; Haloperid

1976
Nervous mechanisms involved in experimentally induced extrapyramidal disturbances.
    Confinia neurologica, 1974, Volume: 36, Issue:4-6

    Topics: Animals; Basal Ganglia Diseases; Benztropine; Brain; Cats; Caudate Nucleus; Cerebellar Nuclei; Chlor

1974
Release from brain tissue of compounds with possible transmitter function: interaction of drugs with these substances.
    British journal of pharmacology, 1969, Volume: 37, Issue:2

    Topics: Acetylcholine; Animals; Brain; Brain Chemistry; Chlorpromazine; Dopamine; Humans; Norepinephrine; Pa

1969
[The role of dopamine in the physiology and pathology of the basal ganglia].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1972, Volume: 72, Issue:4

    Topics: Basal Ganglia; Brain; Caudate Nucleus; Chlorpromazine; Corpus Striatum; Dihydroxyphenylalanine; Dopa

1972
Biochemical and pharmacological aspects of Parkinsonism.
    Acta neurologica Scandinavica. Supplementum, 1972, Volume: 51

    Topics: Animals; Blood-Brain Barrier; Brain; Central Nervous System; Chemoreceptor Cells; Chlorpromazine; Co

1972
The role of brain catecholamines in the regulation of ACTH secretion.
    Advances in neurology, 1974, Volume: 5

    Topics: 17-Hydroxycorticosteroids; Acetylcholine; Adrenal Cortex Hormones; Adrenal Glands; Adrenalectomy; Ad

1974
The pharmacology of parkinsonism (a review).
    Diseases of the nervous system, 1968, Volume: 29, Issue:12

    Topics: Acetylcholine; Animals; Atropa belladonna; Atropine; Central Nervous System; Chlorpromazine; Dextroa

1968

Trials

9 trials available for chlorpromazine and Idiopathic Parkinson Disease

ArticleYear
Kinematic analysis of the reach to grasp movement in Parkinson's and Huntington's disease subjects.
    Neuropsychologia, 1998, Volume: 36, Issue:11

    Topics: Adult; Age of Onset; Aged; Analysis of Variance; Antiparkinson Agents; Basal Ganglia; Chlorpromazine

1998
Implications of phenothiazine side effects: a study of antiparkinsonian agents in an older population.
    Acta psychiatrica Scandinavica, 1975, Volume: 51, Issue:2

    Topics: Adult; Aged; Antipsychotic Agents; Chlorpromazine; Clinical Trials as Topic; Delayed-Action Preparat

1975
Tardive dyskinesia as a possible sequel of long-term therapy with phenothiazines.
    Clinical pediatrics, 1975, Volume: 14, Issue:10

    Topics: Adolescent; Child; Chlorpromazine; Clinical Trials as Topic; Diagnosis, Differential; Dystonia Muscu

1975
The abrupt withdrawal of antiparkinsonian drugs in schizophrenic patients.
    The British journal of psychiatry : the journal of mental science, 1974, Volume: 124, Issue:579

    Topics: Adult; Aged; Antiparkinson Agents; Basal Ganglia Diseases; Behavior; Chlorpromazine; Clinical Trials

1974
A double-blind study of amantadine hydrochloride versus benztropine mesylate in drug-induced parkinsonism.
    Pharmacology, 1974, Volume: 12, Issue:2

    Topics: Administration, Oral; Amantadine; Antiparkinson Agents; Benztropine; Capsules; Chlorpromazine; Clini

1974
[Prophylaxis of neuroleptic parkonsonism with the Bulgarian drug INKhA-17 (Paabainkh) and bellazon].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1968, Volume: 68, Issue:3

    Topics: Bulgaria; Chlorpromazine; Clinical Trials as Topic; Humans; Isoniazid; Mental Disorders; Parasympath

1968
Brain amine concentrations after monoamine oxidase inhibitor administration.
    British medical journal, 1972, Jan-01, Volume: 1, Issue:5791

    Topics: Aged; Alkynes; Autopsy; Brain; Brain Stem; Caudate Nucleus; Chlorpromazine; Dopamine; Humans; Hypoth

1972
Harmine antagonism of drug-induced extra-pyramidal disturbances.
    Psychopharmacologia, 1964, Oct-14, Volume: 6, Issue:4

    Topics: Alkaloids; Anticonvulsants; Chlorpromazine; Clinical Trials as Topic; Encephalitis; Female; Humans;

1964
Effects of L-DOPA on pharmacological parkinsonism.
    Acta psychiatrica Scandinavica, 1966, Volume: 42, Issue:3

    Topics: Adolescent; Adult; Chlorpromazine; Clinical Trials as Topic; Dihydroxyphenylalanine; Female; Haloper

1966

Other Studies

67 other studies available for chlorpromazine and Idiopathic Parkinson Disease

ArticleYear
Design, Synthesis, and Biological Evaluation of Potent 20S Proteasome Activators for the Potential Treatment of α-Synucleinopathies.
    Journal of medicinal chemistry, 2022, 05-12, Volume: 65, Issue:9

    Topics: alpha-Synuclein; Animals; Humans; Intrinsically Disordered Proteins; Mammals; Neurodegenerative Dise

2022
Biopharmaceutical Potential of Selegiline Loaded Chitosan Nanoparticles in the Management of Parkinson's Disease.
    Current drug discovery technologies, 2019, Volume: 16, Issue:4

    Topics: Administration, Intranasal; Animals; Antiparkinson Agents; Brain; Catalase; Catalepsy; Chitosan; Chl

2019
Effects of rotigotine and rotigotine extended-release microsphere therapy on myocardial ischemic injury in mice.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2019, Jun-15, Volume: 134

    Topics: Animals; Cardiotonic Agents; Chlorpromazine; Creatine Kinase, MB Form; Dopamine Agonists; Isoprotere

2019
[Effect of largactil in parkinson syndrome].
    Rassegna di neurologia vegetativa, 1953, Oct-30, Volume: 10, Issue:3

    Topics: Autonomic Agents; Chlorpromazine; Parkinson Disease

1953
[Reversible parkinsonism in the course of largactil therapy of vomiting in pregnancy].
    Journal de medecine de Bordeaux et du Sud-Ouest, 1954, Volume: 131, Issue:7

    Topics: Chlorpromazine; Female; Parkinson Disease; Parkinsonian Disorders; Pregnancy; Pregnancy Complication

1954
[Parkinsonian states appearing during chlorpromazine therapy].
    Journal de medecine de Bordeaux et du Sud-Ouest, 1954, Volume: 131, Issue:9

    Topics: Chlorpromazine; Parkinson Disease

1954
[The effects of high-dosed reserpin (serpasil) treatment and drug-induced parkinsonism-like states on the electroencephalogram].
    Medizinische Klinik, 1955, Aug-05, Volume: 50, Issue:31

    Topics: Antihypertensive Agents; Chlorpromazine; Electroencephalography; Humans; Parkinson Disease; Parkinso

1955
[Hypothesis on the mechanism of action of chlorpromazine (largactil) on the extrapyramidal manifestations of the parkinsonian syndrome].
    Gazzetta medica italiana, 1955, Volume: 114, Issue:10

    Topics: Chlorpromazine; Parkinson Disease; Parkinsonian Disorders

1955
[Psychiatric experiences with megaphen (largactil) and the Rauwolfia alkaloid serpasil with special reference to Parkinson's psychomotor syndrome].
    Der Nervenarzt, 1955, Dec-20, Volume: 26, Issue:12

    Topics: Antihypertensive Agents; Chlorpromazine; Parkinson Disease; Rauwolfia; Reserpine; Schizophrenia; Sec

1955
Parkinsonian reactions following chlorpromazine and reserpine; similar reactions in the same patients.
    A.M.A. archives of neurology and psychiatry, 1956, Volume: 75, Issue:5

    Topics: Antihypertensive Agents; Chlorpromazine; Parkinson Disease; Reserpine; Secologanin Tryptamine Alkalo

1956
[Definition and mode of action of the psychomotor Parkinson syndrome therapeutically induced by serpasil and largactil].
    Monatsschrift fur Psychiatrie und Neurologie, 1956, Volume: 131, Issue:4

    Topics: Antihypertensive Agents; Chlorpromazine; Parkinson Disease; Reserpine; Secologanin Tryptamine Alkalo

1956
Comments on the biological and psychopathological basis of individual variation in chlorpromazine therapy.
    L'Encephale, 1956, Volume: 45, Issue:4

    Topics: Chlorpromazine; Humans; Parkinson Disease; Psychopathology

1956
Comments on the biological and psychopathological basis of individual variation in chlorpromazine therapy.
    L'Encephale, 1956, Volume: 45, Issue:4

    Topics: Chlorpromazine; Humans; Parkinson Disease; Psychopathology

1956
Comments on the biological and psychopathological basis of individual variation in chlorpromazine therapy.
    L'Encephale, 1956, Volume: 45, Issue:4

    Topics: Chlorpromazine; Humans; Parkinson Disease; Psychopathology

1956
Comments on the biological and psychopathological basis of individual variation in chlorpromazine therapy.
    L'Encephale, 1956, Volume: 45, Issue:4

    Topics: Chlorpromazine; Humans; Parkinson Disease; Psychopathology

1956
Psychomotility and parkinsonism in treatment with neuroleptic drugs.
    A.M.A. archives of neurology and psychiatry, 1957, Volume: 78, Issue:5

    Topics: Antipsychotic Agents; Chlorpromazine; Electroconvulsive Therapy; Humans; Mental Disorders; Movement;

1957
[BAL therapy in Parkinson's syndrome caused by largactil].
    Orvosi hetilap, 1957, Aug-25, Volume: 98, Issue:34

    Topics: Chlorpromazine; Dimercaprol; Parkinson Disease

1957
[Psychomotility, extrapyramidal syndrome and mode of action of neuroleptic therapies; chlorpromazine, reserpine and prochlorperazine].
    Der Nervenarzt, 1957, Nov-20, Volume: 28, Issue:11

    Topics: Antipsychotic Agents; Basal Ganglia Diseases; Chlorpromazine; Disease; Extrapyramidal Tracts; Humans

1957
[Parkinsonism-like symptoms caused by chlorpromazine therapy].
    Ceskoslovenska psychiatrie, 1958, Volume: 54, Issue:3

    Topics: Chlorpromazine; Electroconvulsive Therapy; Humans; Parkinson Disease; Parkinsonian Disorders; Psycho

1958
[Contribution to the parkinsonian effects of chlorpromazine & reserpine].
    Casopis lekaru ceskych, 1958, Jul-18, Volume: 97, Issue:30

    Topics: Chlorpromazine; Humans; Parkinson Disease; Reserpine

1958
[Treatment of parkinsonism-like syndromes caused by reserpine & chlorpromazine].
    Der Nervenarzt, 1958, Nov-20, Volume: 29, Issue:11

    Topics: Chlorpromazine; Humans; Parkinson Disease; Parkinsonian Disorders; Piperidines; Reserpine; Syndrome

1958
[Parkinson's disease treated with neuroleptics].
    Nederlands tijdschrift voor geneeskunde, 1959, Jun-20, Volume: 103, Issue:25

    Topics: Antihypertensive Agents; Antipsychotic Agents; Chlorpromazine; Parkinson Disease; Secologanin Trypta

1959
Reversibility of drug-induced parkinsonism.
    The American journal of psychiatry, 1960, Volume: 116

    Topics: Chlorpromazine; Parkinson Disease; Parkinsonian Disorders; Reserpine

1960
Theoretical considerations in parkinsonism induced by tranquilizing drugs.
    Diseases of the nervous system, 1959, Volume: 20

    Topics: Chlorpromazine; Parkinson Disease; Parkinsonian Disorders; Reserpine; Tranquilizing Agents

1959
[Experiences and conclusions in regard to the use of hirepin. Part I].
    Ideggyogyaszati szemle, 1960, Volume: 13

    Topics: Chlorpromazine; Parkinson Disease; Perphenazine; Reserpine

1960
Relationship between anti-acetylcholine and anti-Tremorine activity in anti-parkinsonian and related drugs.
    British journal of pharmacology and chemotherapy, 1962, Volume: 18

    Topics: Acetylcholine; Animals; Antiparkinson Agents; Antipsychotic Agents; Chlorpromazine; Cholinergic Anta

1962
[Chlorpromazine, Jendrassi's maneuver and parkinsonian rigor].
    Bollettino della Societa italiana di biologia sperimentale, 1962, Jul-15, Volume: 38

    Topics: Chlorpromazine; Electroencephalography; Electromyography; Muscle Rigidity; Nervous System Physiologi

1962
[Paradoxical parkinsonian syndrome after drug ingestion in a patient with portacaval anastomosis].
    La Presse medicale, 1963, Mar-09, Volume: 71

    Topics: Chlorpromazine; Parkinson Disease; Parkinsonian Disorders; Portacaval Shunt, Surgical

1963
A study of drug-induced parkinsonism.
    Diseases of the nervous system, 1963, Volume: 24

    Topics: Chlorpromazine; Humans; Mental Disorders; Parkinson Disease; Parkinsonian Disorders; Prochlorperazin

1963
[Occurrence and interpretation of psychomotor parkinsonism in megaphen or largactil prolonged therapy].
    Der Nervenarzt, 1954, Dec-20, Volume: 25, Issue:12

    Topics: Chlorpromazine; Parkinson Disease; Parkinsonian Disorders

1954
[Largactil (R.P.4560) in hypertonic and dyskinetic syndromes].
    Giornale di psichiatria e di neuropatologia, 1954, Volume: 82, Issue:4

    Topics: Chlorpromazine; Chorea; Dyskinesias; Humans; Movement Disorders; Parkinson Disease; Syndrome

1954
[Parkinson like manifestations produced by medicamentation].
    Medizinische Klinik, 1955, Apr-15, Volume: 50, Issue:15

    Topics: Antihypertensive Agents; Chlorpromazine; Humans; Parkinson Disease; Secologanin Tryptamine Alkaloids

1955
[Parkinsonian syndrome following prolonged administration of chlorpromazine with fatal concomitant stroke. Appearance of pallidal lesions].
    Revue neurologique, 1959, Volume: 100

    Topics: Basal Ganglia; Chlorpromazine; Ganglia; Globus Pallidus; Humans; Parkinson Disease; Parkinsonian Dis

1959
Drug-induced extrapyramidal symptoms: their incidence and treatment.
    The American journal of psychiatry, 1967, Volume: 123, Issue:7

    Topics: Chlorpromazine; Chlorprothixene; Extrapyramidal Tracts; Female; Fluphenazine; Humans; Male; Parasymp

1967
Reversible drug-induced parkinsonism. Clinicopathologic study of two cases.
    Archives of neurology, 1982, Volume: 39, Issue:10

    Topics: Aged; Antipsychotic Agents; Chlorpromazine; Haloperidol; Humans; Male; Middle Aged; Parkinson Diseas

1982
[Huntington chorea: report of 16 cases].
    Arquivos de neuro-psiquiatria, 1983, Volume: 41, Issue:2

    Topics: Adult; Aged; Brain Diseases; Chlorpromazine; Dementia; Diagnosis, Differential; Female; gamma-Aminob

1983
The effect of carbidopa and benserazide on human plasma 5-hydroxytryptophan levels.
    Journal of neural transmission, 1982, Volume: 53, Issue:1

    Topics: 5-Hydroxytryptophan; Adult; Benserazide; Carbidopa; Chlorpromazine; Dihydroxyphenylalanine; Humans;

1982
Treatment of Parkinson's disease in a patient with acute intermittent porphyria.
    British journal of clinical pharmacology, 1995, Volume: 40, Issue:1

    Topics: Aged; Antiparkinson Agents; Benserazide; Chlorpromazine; Dopamine Antagonists; Drug Interactions; Fe

1995
Prevalence and characteristics of patients with pseudoakathisia.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2000, Volume: 10, Issue:5

    Topics: Adult; Akathisia, Drug-Induced; Antiparkinson Agents; Antipsychotic Agents; Chlorpromazine; Chronic

2000
Dopamine-stimulated adenylate cyclase activity in the human brain: changes in Parkinsonism.
    Biochemical medicine, 1978, Volume: 19, Issue:3

    Topics: Adenosine Triphosphate; Adenylyl Cyclases; Aged; Brain; Caudate Nucleus; Chlorpromazine; Dopamine; F

1978
"In vivo" release of endogenous neurotransmitters in cat limbic regions: effect of chlorpromazine and of electrical stimulation.
    Naunyn-Schmiedeberg's archives of pharmacology, 1975, Volume: 288, Issue:1

    Topics: Acetylcholine; Animals; Cats; Chlorpromazine; Dopamine; Electric Stimulation; Female; Hippocampus; L

1975
Parkinsonism: animal analogues of the human disorder.
    Research publications - Association for Research in Nervous and Mental Disease, 1976, Volume: 55

    Topics: Animals; Butyrophenones; Chlorpromazine; Disease Models, Animal; Haplorhini; Hydroxydopamines; Levod

1976
[Interaction between L-dopa and other drugs].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1976, Nov-22, Volume: 31, Issue:47

    Topics: Amantadine; Anti-Arrhythmia Agents; Apomorphine; Chlorpromazine; Drug Antagonism; Drug Interactions;

1976
[The phenomenon of experimental motor retardation as one of the manifestations of the Parkinsonian syndrome].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1975, Volume: 75, Issue:4

    Topics: Amphetamine; Animals; Catecholamines; Cats; Caudate Nucleus; Chlorpromazine; Dihydroergotoxine; Dise

1975
Levodopa-induced dyskinesias in Parkinson's disease: clinical and pharmacological classification.
    Movement disorders : official journal of the Movement Disorder Society, 1992, Volume: 7, Issue:2

    Topics: Aged; Apomorphine; Chlorpromazine; Dopamine Agents; Dose-Response Relationship, Drug; Dyskinesia, Dr

1992
H reflex suppression by thalamic stimulation and drug administration.
    Journal of neurosurgery, 1968, Volume: 29, Issue:4

    Topics: Chlorpromazine; Diazepam; Electric Stimulation; Humans; Motor Neurons; Muscle Spindles; Oscillometry

1968
[Comparative biochemical studies in organic parkinsonian syndromes and drug induced parkinsonian syndromes].
    Psychiatria et neurologia, 1966, Volume: 151, Issue:2

    Topics: Alanine Transaminase; Aspartate Aminotransferases; Biochemical Phenomena; Biochemistry; Chlorpromazi

1966
The bucco-linguo-masticatory syndrome as a side-effect of neuroleptics therapy.
    The Psychiatric quarterly, 1967, Volume: 41, Issue:2

    Topics: Adult; Aged; Brain Damage, Chronic; Cheek; Chlorpromazine; Chlorprothixene; Clopenthixol; Female; Ha

1967
Motor disturbance induced by tremorine and oxotremorine.
    Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1970, Volume: 267, Issue:1

    Topics: Acetylcholine; Amines; Animals; Atropine; Biperiden; Brain; Bridged-Ring Compounds; Chlorpromazine;

1970
Actions of levodopa and dopamine in the central nervous system.
    JAMA, 1971, Dec-27, Volume: 218, Issue:13

    Topics: Animals; Apomorphine; Binding Sites; Brain; Central Nervous System; Chlorpromazine; Dihydroxyphenyla

1971
Corpus striatum in paralysis agitans and in perphenazine-injected rats.
    Advances in neurology, 1974, Volume: 5

    Topics: Aged; Amphetamine; Amphetamines; Animals; Basal Ganglia; Caudate Nucleus; Chlorpromazine; Corpus Str

1974
A hypothesis on the preferential destruction of melanized tissues.
    Journal of theoretical biology, 1974, Volume: 48, Issue:1

    Topics: Cell Survival; Chlorpromazine; DNA; Dwarfism; Ear, Inner; Energy Transfer; Humans; Hypogonadism; Mel

1974
The pharmacological control of growth hormone release. Studies on the action of L-dopa and chlorpromazine in normal subjects and patients with Parkinsonism, acromegaly and delayed onset of puberty.
    The Journal of endocrinology, 1973, Volume: 58, Issue:1

    Topics: Acromegaly; Chlorpromazine; Dihydroxyphenylalanine; Glucose Tolerance Test; Growth Hormone; Humans;

1973
The control of melanocyte-stimulating hormone secretion.
    The Journal of endocrinology, 1973, Volume: 58, Issue:2

    Topics: Animals; Brain; Catecholamines; Chlorpromazine; Dihydroxyphenylalanine; Humans; Hypothalamus; Inject

1973
Decreased dopamine and homovanillic acid excretion in a case with chlorpromazine-induced Parkinsonism.
    Research communications in chemical pathology and pharmacology, 1973, Volume: 6, Issue:1

    Topics: Chlorpromazine; Dopamine; Homovanillic Acid; Humans; Male; Parkinson Disease; Parkinson Disease, Sec

1973
Drug-induced experimental Parkinsonism.
    Neuropharmacology, 1973, Volume: 12, Issue:8

    Topics: Animals; Atropine; Benztropine; Butyrophenones; Cats; Chlorpromazine; Dose-Response Relationship, Dr

1973
Effects of L-dopa and chlorpromazine on human growth hormone and TSH secretion in normal subjects and acromegalics.
    Hormone research, 1973, Volume: 4, Issue:5

    Topics: Acromegaly; Adult; Chlorpromazine; Dihydroxyphenylalanine; Female; Glucose; Growth Hormone; Humans;

1973
Physostigmine effects on phenothiazine-induced extrapyramidal reactions.
    Archives of neurology, 1973, Volume: 29, Issue:6

    Topics: Adult; Antiparkinson Agents; Chlorpromazine; Drug Hypersensitivity; Extrapyramidal Tracts; Female; H

1973
Reversal of reserpine-induced bradykinesia by alpha-methyldopa--new light on its modus operandi.
    Brain research, 1974, May-10, Volume: 71, Issue:1

    Topics: Animals; Carbidopa; Chlorpromazine; Dihydroxyphenylalanine; Disease Models, Animal; Disulfiram; Dose

1974
The use of neuroleptic agents in a neurosurgical unit.
    Clinical neurosurgery, 1969, Volume: 16

    Topics: Benperidol; Cerebral Angiography; Chlorpromazine; Craniocerebral Trauma; Electrodes; Epilepsy; Fenta

1969
Clinical implications of monoamine oxidase inhibition.
    Advances in biochemical psychopharmacology, 1972, Volume: 5

    Topics: Brain; Brain Stem; Caudate Nucleus; Chlorpromazine; Depression; Dopamine; Drug Synergism; Humans; Hy

1972
The effect of drugs inducing Parkinson's syndrome on muscle reflex mechanisms. A summary.
    Acta neurologica Scandinavica. Supplementum, 1965, Volume: 13 Pt 2

    Topics: Animals; Chlorpromazine; Electrophysiology; Motor Neurons; Muscles; Parkinson Disease; Phenoxybenzam

1965
Cerebrospinal fluid monoamine catabolites in drug-induced extrapyramidal disorders.
    Neuropharmacology, 1970, Volume: 9, Issue:3

    Topics: Amines; Brain; Chlorpromazine; Extrapyramidal Tracts; Female; Humans; Hydroxyindoleacetic Acid; Move

1970
[Pharmaco-biochemical mechanisms and modern therapy in Parkinsonian syndromes].
    Revue medicale de Liege, 1970, Sep-15, Volume: 25, Issue:18

    Topics: Animals; Central Nervous System; Chlorpromazine; Dihydroxyphenylalanine; Dopamine; Extrapyramidal Tr

1970
More on tick bite in Parkinson's disease.
    The New England journal of medicine, 1971, Sep-23, Volume: 285, Issue:13

    Topics: Animals; Chlorpromazine; Dogs; Humans; Motor Activity; Parkinson Disease; Peripheral Nerves; Tick To

1971
[On the clinical picture of current forms of epidemic encephalitis].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1968, Volume: 68, Issue:3

    Topics: Adolescent; Adult; Autonomic Nervous System; Child; Chlorpromazine; Depersonalization; Encephalitis,

1968
Antiparkinsonism medication for the phenothiazine-induced pyramidal-extrapyramidal syndrome in elderly brain-damaged patients.
    Journal of the American Geriatrics Society, 1965, Volume: 13, Issue:10

    Topics: Aged; Brain Damage, Chronic; Chlorpromazine; Female; Humans; Male; Parkinson Disease; Perphenazine;

1965
[Comparative analysis of mechanical and electrical monosynaptic reflexes in patients with Parkinson's disease in various experimental conditions].
    Bollettino della Societa italiana di biologia sperimentale, 1964, Oct-31, Volume: 40, Issue:20

    Topics: Chlorpromazine; Humans; Parkinson Disease; Phenothiazines; Reflex

1964
[Etiology and therapy of Parkinson's syndrome and related pharmacological concepts shown in experimental models].
    Das Deutsche Gesundheitswesen, 1966, Apr-28, Volume: 21, Issue:17

    Topics: Animals; Brain Chemistry; Chlorpromazine; Dihydroxyphenylalanine; Dopamine; Humans; Hypothermia; Mic

1966
A controlled trial of anti-Parkinson drugs in drug-induced Parkinsonism.
    The British journal of psychiatry : the journal of mental science, 1966, Volume: 112, Issue:487

    Topics: Adolescent; Adult; Chlorpromazine; Haloperidol; Humans; Middle Aged; Orphenadrine; Parasympatholytic

1966