chlorpromazine has been researched along with Hypoxia in 57 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated the cardiovascular effects of chlorpromazine (CPZ) during normoxia and during alveolar hypoxia (HYP) in 9 chronically instrumented piglets aged 10-14 days." | 7.68 | Chlorpromazine attenuates the pulmonary vascular response to isocapneic alveolar hypoxia in piglets. ( Fewell, JE; Hill, DE; Konduri, GG; Taylor, BJ, 1990) |
| "Eighteen newborn infants with severe hypoxia during the course of idiopathic respiratory distress syndrome, pneumonia, persistent fetal circulation or right diaphragmatic hernia were treated with chlorpromazine with the aim of improving arterial oxygenation by a postulated vasodilatory action on the pulmonary circulation." | 7.66 | The effect of chlorpromazine in severe hypoxia in newborn infants. ( Ekström-Jodal, B; Hjalmarson, O; Larsson, LE, 1982) |
| " Thirteen days after hospitalization, she developed severe, protracted, recurrent episodes of hyperventilation; subsequently, she suffered posthyperventilation apnea, which at times was prolonged and association with severe hypoxemia with an arterial oxygen pressure as low as 25 mm Hg." | 7.65 | Posthyperventilation apnea associated with severe hypoxemia. ( Bowers, JT; Flynn, RE; MacDonald, KF, 1976) |
| "In anesthetized, paralyzed, and ventilated rats, hypoxia or intracarotid cyanide excited the carotid chemoafferents, whereas intracarotid dopamine and tyramine inhibited the chemoafferent discharges." | 3.69 | Dopamine or transmitter release from rat carotid body may not be essential to hypoxic chemoreception. ( Reis, DJ; Sun, MK, 1994) |
| "We investigated the cardiovascular effects of chlorpromazine (CPZ) during normoxia and during alveolar hypoxia (HYP) in 9 chronically instrumented piglets aged 10-14 days." | 3.68 | Chlorpromazine attenuates the pulmonary vascular response to isocapneic alveolar hypoxia in piglets. ( Fewell, JE; Hill, DE; Konduri, GG; Taylor, BJ, 1990) |
| "The anti-hypoxic effect of drugs that inhibit different steps of arachidonic acid metabolism was studied using an experimental model of acute hypobaric hypoxia in mice." | 3.67 | Arachidonic acid cascade and anti-hypoxic drugs. ( Nikolov, R, 1984) |
| "Effects of hypoxia on atrioventricular conduction were investigated in the Langendorff-perfused isolated heart of the rabbit with various extracellular calcium concentrations ([Ca2+]) as well as in the presence of verapamil, nifedipine, N-(6-aminohexyl)-5-chloro-1-naphthalenesulphonamide (W-7) and chlorpromazine." | 3.67 | Effects of calcium, calcium entry blockers and calmodulin inhibitors on atrioventricular conduction disturbances induced by hypoxia. ( Anno, T; Kodama, I; Shibata, S; Toyama, J; Yamada, K, 1986) |
| "Eighteen newborn infants with severe hypoxia during the course of idiopathic respiratory distress syndrome, pneumonia, persistent fetal circulation or right diaphragmatic hernia were treated with chlorpromazine with the aim of improving arterial oxygenation by a postulated vasodilatory action on the pulmonary circulation." | 3.66 | The effect of chlorpromazine in severe hypoxia in newborn infants. ( Ekström-Jodal, B; Hjalmarson, O; Larsson, LE, 1982) |
| " Thirteen days after hospitalization, she developed severe, protracted, recurrent episodes of hyperventilation; subsequently, she suffered posthyperventilation apnea, which at times was prolonged and association with severe hypoxemia with an arterial oxygen pressure as low as 25 mm Hg." | 3.65 | Posthyperventilation apnea associated with severe hypoxemia. ( Bowers, JT; Flynn, RE; MacDonald, KF, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 54 (94.74) | 18.7374 |
| 1990's | 2 (3.51) | 18.2507 |
| 2000's | 1 (1.75) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Miller, P | 1 |
| Kemp, PJ | 1 |
| Lewis, A | 1 |
| Chapman, CG | 1 |
| Meadows, HJ | 1 |
| Peers, C | 1 |
| STENDER, HS | 1 |
| HORNYKIEWYTSCH, T | 1 |
| BOELES, JT | 1 |
| BLOK, J | 1 |
| ANKERMANN, H | 2 |
| TABUSSE, L | 1 |
| GIAJA, J | 1 |
| RADULOVIC, J | 1 |
| OBRENOVIC, L | 1 |
| LINDAUR, V | 1 |
| THURAU, K | 1 |
| FISTER, V | 2 |
| DAVILA, D | 2 |
| JILEK, L | 2 |
| TROJAN, S | 2 |
| TANKEVICH, VM | 1 |
| VANLIERE, EJ | 1 |
| LAITL, J | 2 |
| KOLETA, F | 1 |
| MILLER, JA | 1 |
| MILLER, FS | 1 |
| King, LJ | 1 |
| Lowry, OH | 1 |
| Passonneau, JV | 1 |
| Venson, V | 1 |
| Weinstock, M | 1 |
| Scott, JD | 1 |
| Miyahara, M | 1 |
| Okimasu, E | 1 |
| Mikasa, H | 1 |
| Terada, S | 1 |
| Kodama, H | 1 |
| Utsumi, K | 1 |
| Nikolov, R | 1 |
| Larsson, LE | 1 |
| Ekström-Jodal, B | 1 |
| Hjalmarson, O | 1 |
| Araki, H | 1 |
| Peck, RC | 1 |
| Lefer, AM | 1 |
| Sun, MK | 1 |
| Reis, DJ | 1 |
| Panchenko, LF | 1 |
| Mukhankin, AI | 1 |
| Ivkov, NN | 1 |
| Poliakova, GP | 1 |
| Shenoy, MA | 1 |
| Singh, BB | 1 |
| Siddiqui, HH | 1 |
| Malhotra, NK | 1 |
| Bhatia, B | 1 |
| Subramanian, R | 1 |
| Collins, DL | 1 |
| Pomerance, JJ | 1 |
| Travis, KW | 1 |
| Turner, SW | 1 |
| Pappelbaum, SJ | 1 |
| MacDonald, KF | 1 |
| Bowers, JT | 1 |
| Flynn, RE | 1 |
| Steinberg, H | 1 |
| Bassett, DJ | 1 |
| Fisher, AB | 1 |
| Konduri, GG | 1 |
| Fewell, JE | 1 |
| Taylor, BJ | 1 |
| Hill, DE | 1 |
| Weiss, HR | 1 |
| Buchweitz-Milton, E | 1 |
| Anno, T | 1 |
| Kodama, I | 1 |
| Shibata, S | 1 |
| Toyama, J | 1 |
| Yamada, K | 1 |
| Himwich, WA | 1 |
| Davis, JM | 1 |
| Jamieson, D | 1 |
| Van den Brenk, HA | 1 |
| Louros, NC | 1 |
| Papadimitriou, GC | 1 |
| Papapostolou, MG | 1 |
| Winston, JM | 1 |
| Creighton, JM | 1 |
| Roberts, RJ | 1 |
| Pogády, J | 1 |
| Ruscák, M | 1 |
| Orlický, J | 1 |
| Proctor, E | 1 |
| Park, S | 1 |
| Happy, JM | 1 |
| Prange, AJ | 1 |
| Ratra, CK | 1 |
| Badola, RP | 1 |
| Bhargava, KP | 1 |
| Merritt, JH | 1 |
| Medina, MA | 1 |
| Lambotte, L | 2 |
| Nichols, MM | 1 |
| Wood, DW | 1 |
| Downes, JJ | 1 |
| Lecks, HI | 1 |
| Nakae, S | 1 |
| Webb, WR | 1 |
| Salyer, KE | 1 |
| Unal, MO | 1 |
| Cook, WA | 1 |
| Dodds, RP | 1 |
| Williams, GT | 1 |
| Fraunfelder, FT | 1 |
| Burns, RP | 1 |
| Kaeser, HE | 1 |
| Langslet, A | 1 |
| Nebotov, VA | 1 |
| Ulrich, WD | 1 |
| Wirth, J | 1 |
| Maess, M | 1 |
| Messmer, K | 1 |
| Sherwin, I | 1 |
| Redmon, W | 1 |
| Temkov, I | 1 |
| Michailov, SH | 1 |
| Bojkov, B | 1 |
3 reviews available for chlorpromazine and Hypoxia
| Article | Year |
|---|---|
RESISTANCE TO HYPOXIA.
Topics: Acclimatization; Blood Transfusion; Chlorpromazine; Dietary Carbohydrates; Endocrine Glands; Enzymes | 1964 |
Response of brain amino acids to drugs and environmental conditions.
Topics: Amino Acids; Aminobutyrates; Animals; Brain; Brain Chemistry; Central Nervous System Stimulants; Chl | 1972 |
Preservation of the heart.
Topics: Animals; Chlorpromazine; Cryoprotective Agents; Dimethyl Sulfoxide; Dogs; Freezing; Glycerol; Heart; | 1972 |
54 other studies available for chlorpromazine and Hypoxia
| Article | Year |
|---|---|
Acute hypoxia occludes hTREK-1 modulation: re-evaluation of the potential role of tandem P domain K+ channels in central neuroprotection.
Topics: Arachidonic Acid; Cell Membrane; Chlorpromazine; Cloning, Molecular; Electrophysiology; Epitopes; Fl | 2003 |
[The effects of chlorpromazine on radiosensitivity in total body radiation].
Topics: Chlorpromazine; Hypoxia; Oxygen; Radiation Tolerance; Whole-Body Irradiation; X-Rays | 1955 |
The influence of chlorpromazine on the survival time of the corneal reflex during stagnant anoxia.
Topics: Brain; Chlorpromazine; Humans; Hypoxia; Nervous System Physiological Phenomena; Reflex | 1956 |
[Propaphenine and anoxia].
Topics: Chlorpromazine; Hypoxia | 1956 |
[Propaphenine and anoxia].
Topics: Chlorpromazine; Hypoxia | 1956 |
[Propaphenine and anoxia].
Topics: Chlorpromazine; Hypoxia | 1956 |
[Propaphenine and anoxia].
Topics: Chlorpromazine; Hypoxia | 1956 |
[Modified tolerance of anoxia in the guinea pig under the influence of certain drugs: chlorpromazine, acetylcholine and benzyl-imidazoline chlorhydrate].
Topics: Acetylcholine; Chlorpromazine; Drug Tolerance; Guinea Pigs; Hypoxia; Imidazolines; Sympatholytics | 1956 |
[Chlorpromazine (largactil) and cardiac resistance to anoxia].
Topics: Biochemical Phenomena; Chlorpromazine; Heart; Hypoxia | 1957 |
Relationship between chlorpromazine and anoxia.
Topics: Chlorpromazine; Hypoxia; Polycythemia | 1958 |
Renal Na-reabsorption and O2-uptake in dogs during hypoxia and hydrochlorothiazide infusion.
Topics: Animals; Chlorpromazine; Dogs; Humans; Hydrochlorothiazide; Hypoxia; Kidney; Sodium; Sodium, Dietary | 1961 |
[Effect of the anemization and of chlorpromazine on the resistance of albino rats to acute hypoxia].
Topics: Anemia; Animals; Biochemical Phenomena; Chlorpromazine; Hypoxia; Rats | 1959 |
[Influences on resistance of the body against oligemia and ischemia of the CNS during the course of ontogenesis].
Topics: Aging; Central Nervous System; Chlorpromazine; Hyperglycemia; Hypoxia; Ischemia; Pentobarbital | 1963 |
[Differences in influencing the course of anoxia and hypoxia of the central nervous system in ontogenesis].
Topics: Aging; Brain; Central Nervous System; Chlorpromazine; Humans; Hypoglycemia; Hypoxia; Pentobarbital | 1962 |
[GASEOUS STATE OF THE BLOOD AND REMOTE HEMODYNAMIC INDICES IN PATIENTS SURGICALLY TREATED UNDER POTENTIATED ANESTHESIA AND INTUBATION ANESTHESIA].
Topics: Anesthesia; Anesthesia, Endotracheal; Blood Gas Analysis; Chlorpromazine; Hemodynamics; Hibernation; | 1963 |
[RESISTANCE OF THE BODY TO ANOXIA DURING THE COURSE OF ONTOGENESIS AND THE EFFECT OF CHLORPROMAZINE].
Topics: Aging; Body Temperature Regulation; Chlorpromazine; Hyperglycemia; Hypoxia; Metabolism; Pharmacology | 1963 |
[SERUM PROTEINS IN THE RAT FOLLOWING THE ADMINISTRATION OF CHLORPROMAZINE AND IN CHRONIC HYPOXIA].
Topics: Blood Proteins; Chlorpromazine; Hypoxia; Pharmacology; Rats; Research | 1964 |
[Effect of largactil on the survival of young rats in acute hypoxia in relation to the age of the rat and to the environmental temperature].
Topics: Animals; Chlorpromazine; Humans; Hypoxia; Rats; Temperature | 1959 |
[Effect of chlorpromazine on intrauterine fetal aspiration in maternal hypoxia in the rabbit].
Topics: Animals; Chlorpromazine; Fetus; Humans; Hypoxia; Rabbits | 1961 |
Factors in neonatal resistance to anoxia. III. Potentiation by narcosis of the effects of hypothermia in the newborn guinea pig.
Topics: Asphyxia Neonatorum; Chlorpromazine; Guinea Pigs; Humans; Hypothermia; Hypothermia, Induced; Hypoxia | 1962 |
Effects of convulsants on energy reserves in the cerebral cortex.
Topics: Animals; Centrifugation; Cerebral Cortex; Chlorpromazine; Electric Stimulation; Electroshock; Freezi | 1967 |
Effect of various agents on drug-induced opacities of the lens.
Topics: Animals; Cataract; Chlorpromazine; Epinephrine; Female; Hypoxia; Male; Mice; Morphine; Nikethamide; | 1967 |
Improvement of the anoxia-induced mitochondrial dysfunction by membrane modulation.
Topics: Acetophenones; Adenine Nucleotides; Alkaloids; Animals; Benzylisoquinolines; Chlorpromazine; Egtazic | 1984 |
Arachidonic acid cascade and anti-hypoxic drugs.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Betamethasone; Chloroquine; Chlorpromazine; Cyclooxyge | 1984 |
The effect of chlorpromazine in severe hypoxia in newborn infants.
Topics: Chlorpromazine; Humans; Hypoxia; Infant, Newborn; Infant, Newborn, Diseases; Oxygen | 1982 |
Biphasic actions of chlorpromazine and mepacrine on modulation of hepatic cell injury in the perfused cat liver.
Topics: Amines; Animals; Cathepsin D; Cathepsins; Cats; Chemical and Drug Induced Liver Injury; Chlorpromazi | 1981 |
Dopamine or transmitter release from rat carotid body may not be essential to hypoxic chemoreception.
Topics: Afferent Pathways; Amino Acid Oxidoreductases; Animals; Blood Pressure; Carotid Body; Chemoreceptor | 1994 |
[Antihypoxic effect of aminazine].
Topics: Animals; Brain Chemistry; Chlorpromazine; Cyclic AMP; Hypoxia; Male; Rats | 1978 |
[Treatment of asphyxia and post-asphyxia conditions in newborn infants].
Topics: Asphyxia Neonatorum; Central Nervous System Stimulants; Chlorpromazine; Diuretics; Humans; Hyperbari | 1975 |
Hypoxic cytotoxicity of chlorpromazine and the modification of radiation response in E. coli B/r.
Topics: Chlorpromazine; Escherichia coli; Hypoxia; Radiation-Sensitizing Agents | 1978 |
Factors affecting blood glucose and liver glycogen in chlorpromazine-treated mice subjected to simulated altitudes.
Topics: Altitude; Animals; Blood Glucose; Chlorpromazine; Hyperglycemia; Hypoxia; Injections, Intraperitonea | 1979 |
A new approach to congenital posterolateral diaphragmatic hernia.
Topics: Acetylcholine; Blood Gas Analysis; Chlorpromazine; Ductus Arteriosus, Patent; Hernia, Diaphragmatic; | 1977 |
Posthyperventilation apnea associated with severe hypoxemia.
Topics: Adolescent; Apnea; Blood Gas Analysis; Chlorpromazine; Female; Humans; Hyperventilation; Hypoxia; Ma | 1976 |
Depression of pulmonary 5-hydroxytryptamine uptake by metabolic inhibitors.
Topics: Animals; Biological Transport, Active; Carbon Radioisotopes; Chlorpromazine; Chromatography, Thin La | 1975 |
Chlorpromazine attenuates the pulmonary vascular response to isocapneic alveolar hypoxia in piglets.
Topics: Animals; Blood Gas Analysis; Chlorpromazine; Hemodynamics; Hydrogen-Ion Concentration; Hypertension, | 1990 |
Role of alpha-adrenoceptors in the control of the cerebral blood flow response to hypoxia.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Cerebrovascular Circulation; Chlorpromazine; Female; He | 1988 |
Effects of calcium, calcium entry blockers and calmodulin inhibitors on atrioventricular conduction disturbances induced by hypoxia.
Topics: Animals; Atrioventricular Node; Calcium; Calcium Channel Blockers; Calmodulin; Chlorpromazine; Heart | 1986 |
Studies of mechanisms of chemical radiation protection in vivo. 3. Changes in fluorescence of intracellular pyridine nucleotides and modification by extracellular hypoxia.
Topics: Animals; Antidotes; beta-Aminoethyl Isothiourea; Chlorpromazine; Cystamine; Dimethyl Sulfoxide; Extr | 1966 |
Accelerated painless labor.
Topics: Chlorpromazine; Extraembryonic Membranes; Female; Fetal Death; Fetus; Histamine H1 Antagonists; Huma | 1967 |
Alteration of carbon monoxide and hypoxic hypoxia-induced lethality following phenobarbital, chlorpromazine, or alcohol pretreatment.
Topics: Animals; Body Temperature; Carbon Monoxide; Carbon Monoxide Poisoning; Carboxyhemoglobin; Chlorproma | 1974 |
Hypoxia and some therapeutic problems in gerontopsychiatry.
Topics: Aged; Aging; Brain; Brain Chemistry; Chlormethiazole; Chlorpromazine; Glycolysis; Humans; Hypoxia; L | 1972 |
Thyroid action on behavioral-physiological effects and disposition of phenothiazines.
Topics: Animals; Behavior, Animal; Body Temperature; Chlorpromazine; Dose-Response Relationship, Drug; Drug | 1972 |
A study of factors concerned in emesis during spinal anaesthesia.
Topics: Adult; Anesthesia, Spinal; Atropine; Blood Pressure; Chlorpromazine; Female; Humans; Hypoxia; Hyster | 1972 |
Effect of simulated altitude on the disposition of chlorpromazine in mouse brain and liver.
Topics: Altitude; Animals; Biotransformation; Brain; Chlorpromazine; Hypoxia; Liver; Male; Mice; Microsomes, | 1973 |
Use of hepatic cell membrane potential measurement to evaluate new method of liver preservation.
Topics: Acid Phosphatase; Alanine Transaminase; Animals; Aspartate Aminotransferases; Cell Membrane; Cell Me | 1973 |
Managing emergencies in the newborn.
Topics: Anesthesia, Obstetrical; Anti-Bacterial Agents; Apnea; Bronchopneumonia; Chlorpromazine; Cyclopropan | 1974 |
[Description of a computer surveillance system for isolated liver: application to the study of drugs protecting the liver from anoxic lesions].
Topics: Animals; Chlorpromazine; Computers; Dogs; Extracorporeal Circulation; Hypoxia; Isoproterenol; Liver; | 1970 |
The management of respiratory failure in childhood status asthmaticus. Experience with 30 episodes and evolution of a technique.
Topics: Acid-Base Equilibrium; Acidosis; Asthma; Blood Gas Analysis; Cardiac Tamponade; Child; Chlorpromazin | 1968 |
Extended survival of the normothermic anoxic heart with metabolic inhibitors.
Topics: Acetylcholine; Animals; Chlorpromazine; Dogs; Heart; Heart Transplantation; Hypoxia; Magnesium; Pota | 1967 |
Acute reversible lens opacity: caused by drugs, cold, anoxia, asphyxia, stress, death and dehydration.
Topics: Animals; Asphyxia; Cataract; Cats; Chlorpromazine; Cricetinae; Death; Dehydration; Epinephrine; Eyel | 1970 |
[Therapy of polyneuritides].
Topics: Butyrophenones; Chlorpromazine; Glucocorticoids; Humans; Hypoxia; Imipramine; Methotrimeprazine; Nor | 1971 |
Effects of phenothiazines on the release of aspartate aminotransferase from hypothermic asystolic hearts subjected to hypoxia.
Topics: Animals; Aspartate Aminotransferases; Chlorpromazine; Hypoxia; Male; Perfusion; Rats; Thioridazine | 1971 |
[The role and significance of reticular mechanisms in the oxygen saturation of arterial blood (based on the data of oxyhemometry)].
Topics: Blood Gas Analysis; Brain Diseases; Brain Stem; Chlorpromazine; Diencephalon; Extrapyramidal Tracts; | 1967 |
[Oxygen consumption and body temperature of hyperthermic animals after administration of drugs and in hypoxia].
Topics: Animals; Basal Metabolism; Body Temperature; Chlorpromazine; Environmental Exposure; Guinea Pigs; Hy | 1968 |
[The importance of the intestinal system in shock].
Topics: Cardiac Output; Chlorpromazine; Hemodynamics; Humans; Hypoxia; Intestinal Mucosa; Intestine, Small; | 1968 |
Successful treatment in action myoclonus.
Topics: Chlorpromazine; Diazepam; Electroencephalography; Electromyography; Humans; Hypoxia; Male; Middle Ag | 1969 |
[Protective effect of some neuroleptics and of p-diphenol:O2-oxidoreductase (ceruloplasmin) against intoxication hypoxia].
Topics: Animals; Central Nervous System; Ceruloplasmin; Chlorpromazine; Cyanides; Haloperidol; Hypoxia; Inse | 1966 |