chlorpromazine has been researched along with Hypotension, Orthostatic in 20 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Hypotension, Orthostatic: A significant drop in BLOOD PRESSURE after assuming a standing position. Orthostatic hypotension is a finding, and defined as a 20-mm Hg decrease in systolic pressure or a 10-mm Hg decrease in diastolic pressure 3 minutes after the person has risen from supine to standing. Symptoms generally include DIZZINESS, blurred vision, and SYNCOPE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 49-year-old man with severe hypertension and chronic schizophrenia developed marked hypotension with postural syncope following therapy with the combination of chlorpromazine and captopril." | 7.67 | Hypotension with postural syncope secondary to the combination of chlorpromazine and captopril. ( White, WB, 1986) |
| "A 49-year-old man with severe hypertension and chronic schizophrenia developed marked hypotension with postural syncope following therapy with the combination of chlorpromazine and captopril." | 3.67 | Hypotension with postural syncope secondary to the combination of chlorpromazine and captopril. ( White, WB, 1986) |
| "Eighteen patients experienced orthostatic hypotension following injection." | 2.65 | Parenteral chlorpromazine treatment of migraine. ( Iserson, KV, 1983) |
| "Postural hypotension was observed in both patient groups." | 2.65 | Single daily dose chlorpromazine therapy in psychosis. An evaluation. ( Kalyanasundaram, S; Kapur, RL; Machado, TA; Shrikhande, SA, 1981) |
| "Orthostatic hypotension was produced in urethane-anesthetized rabbit by a combination of chlorpromazine (0." | 1.31 | Effect of midodrine on chlorpromazine-induced orthostatic hypotension in rabbits: comparison with amezinium, etilefrine and droxidopa. ( Kato, H; Kurihara, J; Okubo, Y; Suzuki, S; Takata, Y, 2000) |
| "Both prazosin and pentolinium elicited orthostatic hypotension under all four anesthetic conditions." | 1.30 | A rabbit model for evaluation of chlorpromazine-induced orthostatic hypotension. ( Kato, H; Kurihara, J; Okubo, Y; Suzuki, S; Takata, Y, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (90.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 1 (5.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| INGLIS, JM | 1 |
| BARROW, ME | 1 |
| Iserson, KV | 1 |
| Tuason, VB | 1 |
| Escobar, JI | 1 |
| Garvey, M | 1 |
| Schiele, B | 1 |
| Kalyanasundaram, S | 1 |
| Shrikhande, SA | 1 |
| Machado, TA | 1 |
| Kapur, RL | 1 |
| Castellani, S | 1 |
| Ziegler, MG | 1 |
| van Kammen, DP | 1 |
| Alexander, PE | 1 |
| Siris, SG | 1 |
| Lake, CR | 1 |
| LaWall, JS | 1 |
| Takata, Y | 2 |
| Kurihara, J | 2 |
| Suzuki, S | 2 |
| Okubo, Y | 2 |
| Kato, H | 2 |
| Mason, AS | 1 |
| Granacher, RP | 1 |
| DiNicola, AF | 1 |
| Sicard, RE | 1 |
| White, WB | 1 |
| Barnes, TR | 1 |
| Katona, CL | 1 |
| Noe, JM | 1 |
| Aber, RC | 1 |
| Ritter, RM | 1 |
| Davidson, DE | 1 |
| Robinson, TA | 1 |
| Magner, O | 1 |
| Moller, S | 1 |
| Broor, SL | 1 |
| Wig, NN | 1 |
| Wahi, PL | 1 |
| Jefferson, JW | 1 |
| Müller, H | 2 |
| Battegay, R | 2 |
| Gehring, A | 2 |
| Curry, SH | 1 |
5 trials available for chlorpromazine and Hypotension, Orthostatic
| Article | Year |
|---|---|
Parenteral chlorpromazine treatment of migraine.
Topics: Adolescent; Adult; Chlorpromazine; Clinical Trials as Topic; Female; Humans; Hypotension, Orthostati | 1983 |
Loxapine versus chlorpromazine in paranoid schizophrenia: a double-blind study.
Topics: Adult; Basal Ganglia Diseases; Chlorpromazine; Clinical Trials as Topic; Dibenzoxazepines; Dizziness | 1984 |
Single daily dose chlorpromazine therapy in psychosis. An evaluation.
Topics: Adolescent; Adult; Chlorpromazine; Clinical Trials as Topic; Consciousness Disorders; Double-Blind M | 1981 |
Comparison of injectable haloperidol and chlorpromazine.
Topics: Acute Disease; Adult; Age Factors; Aged; Basal Ganglia Diseases; Chlorpromazine; Clinical Trials as | 1972 |
[The blood pressure lowering effect of chlorpromazine and methylperon (Buronil)].
Topics: Adult; Aged; Blood Pressure; Butyrophenones; Chlorpromazine; Clinical Trials as Topic; Depression, C | 1974 |
15 other studies available for chlorpromazine and Hypotension, Orthostatic
| Article | Year |
|---|---|
PREMEDICATION--A REASSESSMENT.
Topics: Anxiety; Anxiety Disorders; Atropine; Barbiturates; Chlordiazepoxide; Chlorpromazine; Drug Therapy; | 1965 |
Plasma norepinephrine and dopamine-beta-hydroxylase activity in schizophrenia.
Topics: Adult; Blood Pressure; Chlorpromazine; Dopamine beta-Hydroxylase; Haloperidol; Humans; Hypotension, | 1982 |
Treatment of psychotropic-caused orthostatic hypotension.
Topics: Adult; Chlorpromazine; Female; Humans; Hypotension, Orthostatic; Imipramine; Middle Aged | 1980 |
A rabbit model for evaluation of chlorpromazine-induced orthostatic hypotension.
Topics: Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Aorta; Blood Pressure; Cardiac Output; | 1999 |
Effect of midodrine on chlorpromazine-induced orthostatic hypotension in rabbits: comparison with amezinium, etilefrine and droxidopa.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Antipsych | 2000 |
Basic principles of rapid neuroleptization.
Topics: Antiparkinson Agents; Antipsychotic Agents; Basal Ganglia Diseases; Chlorpromazine; Fluphenazine; Ha | 1976 |
Letter: Orthostatic hypotension, lactation, and breast cancer secondary to chlorpromazine administration.
Topics: Breast Neoplasms; Chlorpromazine; Female; Growth Hormone; Humans; Hypotension, Orthostatic; Lactatio | 1975 |
Hypotension with postural syncope secondary to the combination of chlorpromazine and captopril.
Topics: Blood Pressure; Captopril; Chlorpromazine; Drug Synergism; Drug Therapy, Combination; Humans; Hypert | 1986 |
Susceptibility to drug-induced hypotension in post-partum psychosis.
Topics: Adult; Chlorpromazine; Female; Humans; Hypotension, Orthostatic; Pimozide; Pregnancy; Psychotic Diso | 1986 |
Treatment of fever in burned children. A therapeutic program.
Topics: Acetaminophen; Adrenergic alpha-Antagonists; Burns; Child; Child, Preschool; Chlorpromazine; Fever; | 1973 |
A study of toxic effects of certain psychotropic drugs with special emphasis on their cardiotoxicity.
Topics: Adolescent; Adult; Cardiovascular Diseases; Chlorpromazine; Female; Humans; Hypotension, Orthostatic | 1973 |
Atypical manifestations of postural hypotension.
Topics: Adult; Blood Pressure; Chlorpromazine; Diagnosis, Differential; Humans; Hypotension, Orthostatic; Lo | 1972 |
[Orthostatic hypotension as autonomic side-effect of neuroleptic therapy and attempts at its medicamentous compensation].
Topics: Adolescent; Adult; Age Factors; Aged; Blood Pressure; Chlorpromazine; Chlorprothixene; Female; Human | 1969 |
Chlorpromazine: concentrations in plasma, excretion in urine and duration of effect.
Topics: Administration, Oral; Chlorpromazine; Humans; Hypotension, Orthostatic; Injections, Intramuscular; P | 1971 |
[Orthostatic dysregulation as an adverse effect of the therapy with neuroleptics. Compensating attempt with Effortil-PL and Dihydergot].
Topics: Adult; Chlorpromazine; Depression; Ergotamine; Female; Humans; Hypotension, Orthostatic; Middle Aged | 1969 |