chlorpromazine has been researched along with Hypoglycemia in 31 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Hypoglycemia: A syndrome of abnormally low BLOOD GLUCOSE level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the CENTRAL NERVOUS SYSTEM resulting in HUNGER; SWEATING; PARESTHESIA; impaired mental function; SEIZURES; COMA; and even DEATH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The primary site of action of insulin hypoglycemia to induce ACTH secretion was investigated in rats with medial basal hypothalamic ablation (MBHA), medial basal hypothalamic deafferentation (MBHD), and chlorpromazine-morphine-pentobarbital (C-M-P) treatment." | 3.66 | Hypoglycemia stimulates ACTH secretion through a direct effect on the basal hypothalamus. ( Aizawa, T; Greer, MA; Yasuda, N, 1981) |
| "The authors studied basal HGH levels and HGH response to insulin-induced hypoglycemia in 12 schizophrenic patients who had been treated with 200--450 mg/day of chlorpromazine for 6 months to 4 years compared with 12 schizophrenic patients who had received no drugs and 15 normal control subjects." | 3.66 | Effect of chlorpromazine on human growth hormone. ( Beg, AA; Dash, RJ; Varma, VK, 1979) |
| "Chlorpromazine has very likely been responsible for a considerable increase in the prevalence of diabetes in hospitalized psychotics, while antidepressants can produce useful improvement of diabetic control, especially in brittle diabetics." | 1.26 | The effects of psychotropic drugs and diuretics on blood glucose levels in diabetes mellitus. ( Zumoff, B, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| PERSIC, N | 1 |
| ROGINA, V | 1 |
| BOZOVIC, M | 1 |
| CHRISTY, NP | 1 |
| LONGSON, D | 1 |
| HORWITZ, WA | 1 |
| KNIGHT, MM | 1 |
| HASSELBLATT, A | 2 |
| SCHUSTER, R | 1 |
| HAUN, G | 1 |
| HUDEPOHL, M | 1 |
| LEDERBOGEN, K | 1 |
| TROJAN, S | 1 |
| JILEK, L | 1 |
| ZSCHORNACK, MR | 1 |
| JAROSS, W | 1 |
| TIWARI, NM | 1 |
| BHIDE, MB | 1 |
| SEN, SC | 1 |
| MOORE, KE | 1 |
| SAWDY, LC | 1 |
| SHAUL, SR | 1 |
| HAULICA, I | 1 |
| CAPALNA, S | 1 |
| NESTIANU, V | 1 |
| BORDEIANU, A | 1 |
| BADESCU, A | 1 |
| TRETHOWAN, WH | 1 |
| Buckle, RM | 1 |
| Guillebaud, J | 1 |
| Aizawa, T | 1 |
| Yasuda, N | 1 |
| Greer, MA | 1 |
| Sachar, EJ | 1 |
| Federspil, G | 2 |
| Zaccaria, M | 1 |
| De Palo, C | 1 |
| Zago, E | 1 |
| Erle, G | 1 |
| Sicolo, N | 1 |
| Scandellari, C | 1 |
| Zumoff, B | 1 |
| Beg, AA | 1 |
| Varma, VK | 1 |
| Dash, RJ | 1 |
| Suchmanová, I | 1 |
| Trejbalová, L | 1 |
| Mechír, J | 1 |
| Trejbal, D | 1 |
| Rybárová, E | 1 |
| Machanová, Y | 1 |
| Pokorná, I | 1 |
| Lister, RC | 1 |
| Underwood, LE | 1 |
| Marshall, RN | 1 |
| Friesen, HG | 1 |
| Van Wyk, JJ | 1 |
| Frantz, AG | 1 |
| Suh, HK | 1 |
| Franzén, G | 1 |
| Lambert, AE | 1 |
| Henquin, JC | 1 |
| Orci, L | 1 |
| Saldanha, VF | 1 |
| Havard, CW | 1 |
| Bird, R | 1 |
| Gardner, R | 1 |
| Sato, T | 1 |
| McIntyre, HB | 1 |
| Odell, WD | 1 |
| Susten, AS | 1 |
| Mennear, JH | 1 |
| Miya, TS | 1 |
| Nichols, MM | 1 |
| Casara, D | 1 |
| Stauffacher, W | 1 |
| Knobil, E | 1 |
| Meyer, V | 1 |
| Lichko, AE | 1 |
| Braverman, LB | 1 |
2 reviews available for chlorpromazine and Hypoglycemia
| Article | Year |
|---|---|
Evidence for neuroendocrine abnormalities in the major mental illnesses.
Topics: Adrenocorticotropic Hormone; Aged; Amphetamine; Bipolar Disorder; Chlorpromazine; Circadian Rhythm; | 1975 |
L-DOPA and the control of prolactin secretion.
Topics: Adenoma, Chromophobe; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain Diseases; Breast | 1974 |
29 other studies available for chlorpromazine and Hypoglycemia
| Article | Year |
|---|---|
[Effect of largactil on insulin hypoglycemia].
Topics: Chlorpromazine; Humans; Hypoglycemia; Insulin | 1955 |
Inhibitory effect of chlorpromazine upon the adrenal cortical response to insulin hypoglycemia in man.
Topics: Adrenal Cortex Hormones; Chlorpromazine; Convulsive Therapy; Humans; Hypoglycemia; Insulin | 1957 |
[Effects of megaphen and veronal on rastinon hypoglycemia].
Topics: Barbital; Barbiturates; Chlorpromazine; Hypoglycemia; Hypoglycemic Agents; Pancreatic Diseases; Tolb | 1958 |
[The significance of the sympathetic innervation of the liver for the inhibitory effects of chlorpromazine (Megaphen) and veronal on rastinon hypoglycemia].
Topics: Barbital; Barbiturates; Chlorpromazine; Hypoglycemia; Liver; Pancreatic Diseases; Tolbutamide | 1960 |
[Inhibition of the hypoglycemic effect of rastinon by megaphen and its elimination by pendiomide].
Topics: Biological Transport; Bis-Trimethylammonium Compounds; Chlorpromazine; Hypoglycemia; Hypoglycemic Ag | 1963 |
[Differences in influencing the course of anoxia and hypoxia of the central nervous system in ontogenesis].
Topics: Aging; Brain; Central Nervous System; Chlorpromazine; Humans; Hypoglycemia; Hypoxia; Pentobarbital | 1962 |
[DRAMATIC INCIDENTS DURING THE TREATMENT WITH ORAL ANTIDIABETICS].
Topics: Acidosis; Carbohydrates; Chlorpromazine; Diabetes Mellitus; Diabetic Coma; Diabetic Ketoacidosis; Ge | 1963 |
EFFECT OF CHLORPROMAZINE AND RELATED PHENOTHIAZINES ON EPINEPHRINE AND INSULIN INDUCED RESPONSE ON BLOOD SUGAR.
Topics: Animals; Blood Glucose; Chlorpromazine; Epinephrine; Hyperglycemia; Hypoglycemia; Insulin; Mice; Pha | 1964 |
EFFECTS OF D-AMPHETAMINE ON BLOOD GLUCOSE AND TISSUE GLYCOGEN LEVELS OF ISOLATED AND AGGREGATED MICE.
Topics: Amino Acids; Biochemical Phenomena; Biochemistry; Blood Glucose; Brain Chemistry; Chlorpromazine; De | 1965 |
CONTRIBUTIONS TO THE STUDY OF GAMMA-AMINOBUTYRIC ACID (GABA) IN THE HYPOTHALAMO-HYPOPHYSEAL PATHWAYS.
Topics: Aminobutyrates; Chlorpromazine; Dogs; Electroencephalography; gamma-Aminobutyric Acid; Histocytochem | 1964 |
Persistent sensory symptoms following spontaneous hypoglycemia: response to chlorpromazine.
Topics: Chlorpromazine; Humans; Hypoglycemia; Sensation | 1955 |
Hypoglycaemic coma occurring during treatment with chlorpromazine and orphenadrine.
Topics: Blood Glucose; Chlorpromazine; Coma; Female; Humans; Hypoglycemia; Mental Disorders; Middle Aged; Or | 1967 |
Hypoglycemia stimulates ACTH secretion through a direct effect on the basal hypothalamus.
Topics: Adrenocorticotropic Hormone; Animals; Blood Glucose; Brain; Chlorpromazine; Corticosterone; Hypoglyc | 1981 |
[Medical treatment of spontaneous hypoglycemic syndromes].
Topics: Adenoma, Islet Cell; Chlorpromazine; Diazoxide; Fasting; Glucagon; Glucose; Humans; Hypoglycemia; Li | 1979 |
The effects of psychotropic drugs and diuretics on blood glucose levels in diabetes mellitus.
Topics: Blood Glucose; Chlorpromazine; Diabetes Mellitus; Humans; Hyperglycemia; Hypoglycemia; Psychotropic | 1979 |
Effect of chlorpromazine on human growth hormone.
Topics: Adolescent; Adult; Child; Chlorpromazine; Dose-Response Relationship, Drug; Female; Growth Hormone; | 1979 |
[Personal experience with monitoring the hormone response to insulin hypoglycemia and chlorpromazine in controls and in patients with diencephalo-pituitary disorders].
Topics: Adult; Chlorpromazine; Female; Growth Hormone; Hormones; Humans; Hydrocortisone; Hypoglycemia; Hypot | 1988 |
Evidence for a direct effect of thyrotropin-releasing hormone (TRH) on prolactin release in humans.
Topics: Adrenal Insufficiency; Aged; Binding, Competitive; Breast Neoplasms; Chlorpromazine; Cortisone; Fema | 1974 |
Serum cortisol in chronic schizophrenia. A study of the adrenocortical response to intravenously administered insulin and ACTH.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Age Factors; Aged; Amitriptyline; Blood Glucose; Chlorp | 1971 |
Chlorpromazine in malignant insulinoma.
Topics: Adenoma, Islet Cell; Chlorpromazine; Female; Humans; Hypoglycemia; Middle Aged | 1972 |
The effect of chlorpromazine on pituitary function.
Topics: Adolescent; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; Blood | 1972 |
Glycemic effects of solanine in rats.
Topics: Adrenalectomy; Animals; Blood Glucose; Chlorpromazine; Ergotamine; Female; Glucose Tolerance Test; G | 1967 |
New drug for schizophrenia?
Topics: Chlorpromazine; Drug Synergism; Heart Arrest; Humans; Hypoglycemia; Hypotension; Phenothiazines; Pro | 1974 |
Physiological control of growth hormone in the rabbit.
Topics: Animals; Arginine; Blood Glucose; Chlorpromazine; Depression, Chemical; Electric Stimulation; Estrog | 1974 |
Effect of chlorpromazine on glucose and tolbutamide-stimulated insulin release in the adrenalectomized rat.
Topics: Adrenal Glands; Adrenalectomy; Animals; Antigens; Blood Glucose; Chlorpromazine; Drug Interactions; | 1973 |
Managing emergencies in the newborn.
Topics: Anesthesia, Obstetrical; Anti-Bacterial Agents; Apnea; Bronchopneumonia; Chlorpromazine; Cyclopropan | 1974 |
Chlorpromazine in the treatment of endogenous organic hyperinsulinism.
Topics: Adult; Bendroflumethiazide; Blood Glucose; Chlorpromazine; Diazoxide; Female; Glucose Tolerance Test | 1974 |
Observations on the secretion of growth hormone, and its blockade, in the rhesus monkey.
Topics: Animals; Arousal; Blood Glucose; Chlorpromazine; Fatty Acids, Nonesterified; Growth Hormone; Haplorh | 1968 |
[Protracted (unaffected by glucose) insulin comas, their cause, clinical picture and treatment].
Topics: Amobarbital; Barbiturates; Chlorpromazine; Convulsive Therapy; Depressive Disorder, Major; Encephali | 1970 |