chlorpromazine has been researched along with Hyperactivity, Motor in 43 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The hyperactivity and hyperpyrexia produced by L-tryptophan in rats treated with a monoamine oxidase inhibitor was inhibited by chlorpromazine." | 3.65 | Inhibitory effect of chlorpromazine on the syndrome of hyperactivity produced by L-tryptophan or 5-methoxy-N,N-dimethyltryptamine in rats treated with a monoamine oxidase inhibitor. ( Grahame-Smith, DG, 1971) |
| "Chlorpromazine was effective for the majority of the children, but reduced only hyperactivity, having no demonstrable effect on distractibility, aggressivity or excitability." | 2.64 | Comparison of the effects of chlorpromazine, dextroamphetamine and methylphenidate on the behaviour and intellectual functioning of hyperactive children. ( Douglas, V; Minde, K; Sykes, D; Weiss, G; Werry, J, 1971) |
| " While typical antipsychotics are often switched to atypical agents when adverse effects become limiting, there is little preclinical information to support this strategy, both in terms of efficacy and side effects." | 1.32 | Combined treatment of quetiapine with haloperidol in animal models of antipsychotic effect and extrapyramidal side effects: comparison with risperidone and chlorpromazine. ( Matsuoka, N; Mutoh, S; Shirakawa, K; Tada, M, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 42 (97.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (2.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| HORENSTEIN, S | 2 |
| RAITT, JR | 1 |
| NELSON, JW | 1 |
| TYE, A | 1 |
| Tada, M | 1 |
| Shirakawa, K | 1 |
| Matsuoka, N | 1 |
| Mutoh, S | 1 |
| Burakova, NS | 1 |
| Morgenstern, R | 1 |
| Fink, H | 1 |
| Oelssner, W | 1 |
| Salzinger, K | 1 |
| Köhler, C | 1 |
| Haglund, L | 1 |
| Ogren, SO | 1 |
| Angeby, T | 1 |
| Vatsek, Ia | 1 |
| Lambert, NM | 1 |
| Windmiller, M | 1 |
| Sandoval, J | 1 |
| Moore, B | 1 |
| Výborová, L | 1 |
| Náhunek, K | 1 |
| Balastíková, B | 1 |
| Misurec, J | 1 |
| Weiss, G | 7 |
| Hechtman, L | 1 |
| Perlman, T | 1 |
| Hopkins, J | 1 |
| Wener, A | 1 |
| Kruger, E | 1 |
| Danielson, U | 1 |
| Elman, M | 1 |
| Minde, KK | 1 |
| Langlais, PJ | 1 |
| Huang, PC | 1 |
| Gabay, S | 1 |
| Carman, JS | 1 |
| Tucker, LS | 1 |
| Weinstock, M | 1 |
| Speiser, Z | 1 |
| Kamianov, IM | 1 |
| Kupisk, AG | 1 |
| Katsen, IZ | 1 |
| Grahame-Smith, DG | 1 |
| Arushanian, EB | 1 |
| Millichap, JG | 1 |
| Krager, JM | 1 |
| Safer, DJ | 2 |
| Greenberg, LM | 1 |
| Deem, MA | 1 |
| McMahon, S | 1 |
| Allen, RP | 1 |
| Bhatt, DR | 1 |
| Hattwick, MA | 1 |
| Gerdsen, R | 1 |
| Emmons, RW | 1 |
| Johnson, HN | 1 |
| Ianzito, BM | 1 |
| Liskow, B | 1 |
| Stewart, MA | 1 |
| Cytawa, J | 1 |
| Kutulas, G | 1 |
| Freibergs, V | 1 |
| Douglas, VI | 1 |
| Lapierre, J | 1 |
| Amin, M | 1 |
| Hattangadi, S | 1 |
| Werry, J | 2 |
| Minde, K | 3 |
| Douglas, V | 2 |
| Sykes, D | 2 |
| Kornetsky, C | 1 |
| Tewfik, GI | 1 |
| Jain, VK | 1 |
| Harcup, M | 1 |
| Magowan, S | 1 |
| Krystof, J | 1 |
| Zyg, J | 1 |
| Mitkiewicz, S | 1 |
| Kaczyński, J | 1 |
| Mendelson, N | 1 |
| Howell, MC | 1 |
| Rever, GW | 1 |
| Scholl, ML | 1 |
| Trowbridge, F | 1 |
| Rutledge, A | 1 |
| Lucas, AR | 1 |
| Weiss, M | 1 |
| Ermolina, LA | 1 |
| Rapoport, J | 1 |
| Abramson, A | 1 |
| Alexander, D | 1 |
| Lott, I | 1 |
| Keros, P | 1 |
| Gurovich, IIa | 1 |
| Fleĭs, EP | 1 |
| Ott, T | 1 |
| Matthies, H | 1 |
| Ganguly, DK | 1 |
| Malhtora, CL | 1 |
5 reviews available for chlorpromazine and Hyperactivity, Motor
| Article | Year |
|---|---|
[Extrapyramidal movement disorders arising during treatment of psychoses with drugs].
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Chlorpromazine; Humans; Hyperkinesis; Movement Disorde | 1976 |
Hyperactive children and the efficacy of psychoactive drugs as a treatment intervention.
Topics: Amphetamines; Central Nervous System Stimulants; Child Behavior; Chlordiazepoxide; Chlorpromazine; C | 1976 |
[The role of dopamine in the physiology and pathology of the basal ganglia].
Topics: Basal Ganglia; Brain; Caudate Nucleus; Chlorpromazine; Corpus Striatum; Dihydroxyphenylalanine; Dopa | 1972 |
Prochlorperazine--a review of the literature since 1956.
Topics: Aged; Animals; Antiemetics; Child; Chlorpromazine; Clinical Trials as Topic; Dogs; Drug Hypersensiti | 1969 |
Psychoactive drugs in the immature organism.
Topics: Amphetamine; Animals; Autistic Disorder; Behavior, Animal; Catecholamines; Child; Child Behavior; Ch | 1970 |
10 trials available for chlorpromazine and Hyperactivity, Motor
| Article | Year |
|---|---|
Clozapin in psychomotor instability. A controlled study.
Topics: Adolescent; Child; Child, Preschool; Chlorpromazine; Clinical Trials as Topic; Clozapine; Dibenzazep | 1978 |
Effect of long-term treatment of hyperactive children with methylphenidate.
Topics: Child; Child Behavior Disorders; Chlorpromazine; Clinical Trials as Topic; Drug Evaluation; Electroc | 1975 |
Effects of dextroamphetamine, chlorpromazine, and hydroxyzine on behavior and performance in hyperactive children.
Topics: Child; Chlorpromazine; Clinical Trials as Topic; Depression; Dextroamphetamine; Dose-Response Relati | 1972 |
Drug comparison in hyperactive children.
Topics: Child; Chlorpromazine; Clinical Trials as Topic; Dextroamphetamine; Evaluation Studies as Topic; Hum | 1973 |
The effect of chlorpromazine on concept learning in hyperactive children under two conditions of reinforcement.
Topics: Analysis of Variance; Child; Chlorpromazine; Clinical Trials as Topic; Concept Formation; Humans; Hy | 1968 |
Prochlorperazine--a review of the literature since 1956.
Topics: Aged; Animals; Antiemetics; Child; Chlorpromazine; Clinical Trials as Topic; Dogs; Drug Hypersensiti | 1969 |
Studies on the hyperactive child. V. The effects of dextroamphetamine and chlorpromazine on behaviour and intellectual functioning.
Topics: Aggression; Child; Child Behavior Disorders; Chlorpromazine; Clinical Trials as Topic; Dextroampheta | 1968 |
Psychoactive drugs in the immature organism.
Topics: Amphetamine; Animals; Autistic Disorder; Behavior, Animal; Catecholamines; Child; Child Behavior; Ch | 1970 |
Effectiveness of various tranquilisers in the management of senile restlessness.
Topics: Aged; Carbamates; Chlorpromazine; Clinical Trials as Topic; Dementia; Female; Haloperidol; Humans; H | 1970 |
Comparison of the effects of chlorpromazine, dextroamphetamine and methylphenidate on the behaviour and intellectual functioning of hyperactive children.
Topics: Child; Child Behavior Disorders; Chlorpromazine; Dextroamphetamine; Female; Humans; Hyperkinesis; Le | 1971 |
30 other studies available for chlorpromazine and Hyperactivity, Motor
| Article | Year |
|---|---|
Reserpine and chlorpromazine in hyperactive mental defectives.
Topics: Chlorpromazine; Diet, Reducing; Hyperkinesis; Intellectual Disability; Reserpine | 1957 |
Reserpine and chlorpromazine in hyperactive mental defectives.
Topics: Chlorpromazine; Diet, Reducing; Hyperkinesis; Intellectual Disability; Reserpine | 1957 |
Reserpine and chlorpromazine in hyperactive mental defectives.
Topics: Chlorpromazine; Diet, Reducing; Hyperkinesis; Intellectual Disability; Reserpine | 1957 |
Reserpine and chlorpromazine in hyperactive mental defectives.
Topics: Chlorpromazine; Diet, Reducing; Hyperkinesis; Intellectual Disability; Reserpine | 1957 |
Effect of chlorpromazine on septal hyperactivity in the rat.
Topics: Animals; Brain; Chlorpromazine; Emotions; Hyperkinesis; Rats | 1961 |
Combined treatment of quetiapine with haloperidol in animal models of antipsychotic effect and extrapyramidal side effects: comparison with risperidone and chlorpromazine.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Administration, Oral; Animals; Antipsychotic Agents; Basal G | 2004 |
[A case of hyperkinesia caused by unilateral lesion of the medial part of the thalamus in a dog].
Topics: Animals; Brain Injuries; Chlorpromazine; Dogs; Head; Humans; Hyperkinesis; Movement Disorders; Paras | 1966 |
LSD-potentiated apomorphine hypermotility: a model for differentiating antipsychotic drugs.
Topics: Animals; Apomorphine; Chlorpromazine; Clozapine; Disease Models, Animal; Drug Antagonism; Haloperido | 1983 |
The behavioral mechanism to explain abnormal behavior.
Topics: Behavior; Chlorpromazine; Conditioning, Operant; Dose-Response Relationship, Drug; Extinction, Psych | 1980 |
Regional blockade by neuroleptic drugs of in vivo 3H-spiperone binding in the rat brain. Relation to blockade of apomorphine induced hyperactivity and stereotypies.
Topics: Animals; Apomorphine; Binding, Competitive; Brain; Butyrophenones; Chlorpromazine; Clozapine; Halope | 1981 |
Hyperactives as young adults: a controlled prospective ten-year follow-up of 75 children.
Topics: Adolescent; Adult; Child Development; Chlorpromazine; Female; Follow-Up Studies; Humans; Hyperkinesi | 1979 |
Editorial: The hyperactive child.
Topics: Age Factors; Child; Child Behavior Disorders; Child, Preschool; Chlorpromazine; Dextroamphetamine; H | 1975 |
Regional neurochemical studies on the effect of beta, beta'-iminodipropionitrile (IDPN) in the rat.
Topics: Animals; Biogenic Amines; Brain; Brain Mapping; Chlorpromazine; Dopamine; Female; Humans; Hyperkines | 1975 |
Letter: Benztropine in childhood hyperkinesis.
Topics: Adolescent; Benztropine; Child; Chlorpromazine; Humans; Hyperkinesis; Male; Methylphenidate; Tropane | 1973 |
The effect of dl-propranolol, d-propranolol and practolol on the hyperactivity induced in rats by prolonged isolation.
Topics: Acetanilides; Adrenergic beta-Antagonists; Amino Alcohols; Animals; Behavior, Animal; Chlorpromazine | 1973 |
[Experience with the use of midantan for treatment and prevention of the neuroleptic syndrome].
Topics: Adult; Amantadine; Antiparkinson Agents; Antipsychotic Agents; Catatonia; Chlorpromazine; Facial Mus | 1973 |
Inhibitory effect of chlorpromazine on the syndrome of hyperactivity produced by L-tryptophan or 5-methoxy-N,N-dimethyltryptamine in rats treated with a monoamine oxidase inhibitor.
Topics: Animals; Brain; Chlorpromazine; Drug Synergism; Fenclonine; Fever; Humans; Hyperkinesis; Male; Monoa | 1971 |
Drugs in management of hyperkinetic and perceptually handicapped children.
Topics: Anticonvulsants; Central Nervous System Stimulants; Child; Child, Preschool; Chlordiazepoxide; Chlor | 1968 |
Type and prevalence of medication used in the treatment of hyperactive children.
Topics: Child; Child Behavior Disorders; Chlorpromazine; Dextroamphetamine; Diphenhydramine; Education, Spec | 1974 |
Human rabies. Diagnosis, complications, and management.
Topics: Animals; Antibodies, Viral; Apnea; Autopsy; Blood; Brain; Carbon Dioxide; Child; Chlorpromazine; Dia | 1974 |
Reaction to LSD in a two-year-old child.
Topics: Child, Preschool; Chlorpromazine; Fear; Gastric Lavage; Hallucinations; Humans; Hyperkinesis; Lyserg | 1972 |
Does chlorpromazine facilitate recovery of emotional behaviour in septal forebrain lesioned rats?
Topics: Animals; Behavior, Animal; Brain; Chlorpromazine; Diencephalon; Humans; Hyperkinesis; Limbic System; | 1973 |
Withdrawal symptoms after long-term treatment with neuroleptics.
Topics: Adult; Aged; Blood Circulation; Chlorpromazine; Fever; Humans; Hyperkinesis; Hypotension; Hypothermi | 1972 |
A 5-year follow-up study of 91 hyperactive school children.
Topics: Adolescent; Child; Chlorpromazine; Cognition Disorders; Dextroamphetamine; Female; Follow-Up Studies | 1972 |
Hyperactivity in children: types, diagosis, drug therapy, approaches to management.
Topics: Amphetamine; Anxiety; Attention; Attention Deficit Disorder with Hyperactivity; Brain Damage, Chroni | 1972 |
Methylphenidate hallucinosis.
Topics: Administration, Oral; Adolescent; Age Factors; Alopecia; Catatonia; Child; Chloral Hydrate; Chlorpro | 1971 |
[Febrile states in schizophrenia following a paroxysmal course].
Topics: Adolescent; Adult; Catatonia; Chlorpromazine; Dementia; Female; Fever; Humans; Hyperkinesis; Male; M | 1971 |
Playroom observations of hyperactive children on medication.
Topics: Child; Child Behavior; Child, Preschool; Chlorpromazine; Dextroamphetamine; Evaluation Studies as To | 1971 |
[Problem. Hyperemesis gravidarum].
Topics: Adult; Chlorpromazine; Female; Humans; Hyperemesis Gravidarum; Hyperkinesis; Pregnancy; Psychopharma | 1970 |
[A chronic extrapyramidal syndrome as a complication of neuroleptic therapy].
Topics: Aged; Bipolar Disorder; Chlorpromazine; Chronic Disease; Extrapyramidal Tracts; Female; Haloperidol; | 1969 |
[Differentiation of neuroleptic and psychosedative effects in screening].
Topics: Animals; Chlordiazepoxide; Chlorpromazine; Depression, Chemical; Diazepam; Humans; Hyperkinesis; Hyp | 1969 |
Treatment of hyperactivity in children.
Topics: Child; Chlorpromazine; Dextroamphetamine; Female; Humans; Hyperkinesis; Male; Methylphenidate; Thior | 1970 |
Some neuropharmacological and behavioural effects of an active fraction from Herpestis monniera, Linn (Brahmi).
Topics: Amphetamine; Animals; Body Temperature; Chlorpromazine; Drug Synergism; Humans; Hyperkinesis; Hypoth | 1967 |