chlorpromazine has been researched along with Hiccough in 41 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study is aimed at investigating the clinical efficacy of anisodamine combined with chlorpromazine on intractable hiccups after stroke." | 8.12 | Observation of Clinical Efficacy of Anisodamine and Chlorpromazine in the Treatment of Intractable Hiccup after Stroke. ( Wang, J; Wang, L; Wen, L; Zhang, S; Zhu, Q, 2022) |
| "Agranulocytosis, a severe decrease or absence of neutrophils, is a side effect of several medications, including chlorpromazine." | 8.12 | A Medication Hiccup: Chlorpromazine-Induced Agranulocytosis in a 72-Year-Old Male. ( Kobylarz, Z; Lambert, D; Nothem, ME; Scholcoff, C, 2022) |
| "It stopped hiccough in five of seven patients treated and partially controlled it in the other two." | 5.23 | Emesis and hiccough; treatment with chlorpromazine. ( REDEKER, AG; STEWART, BL, 1954) |
| "This study is aimed at investigating the clinical efficacy of anisodamine combined with chlorpromazine on intractable hiccups after stroke." | 4.12 | Observation of Clinical Efficacy of Anisodamine and Chlorpromazine in the Treatment of Intractable Hiccup after Stroke. ( Wang, J; Wang, L; Wen, L; Zhang, S; Zhu, Q, 2022) |
| "Agranulocytosis, a severe decrease or absence of neutrophils, is a side effect of several medications, including chlorpromazine." | 4.12 | A Medication Hiccup: Chlorpromazine-Induced Agranulocytosis in a 72-Year-Old Male. ( Kobylarz, Z; Lambert, D; Nothem, ME; Scholcoff, C, 2022) |
| "Hiccups are familiar to everyone, but remain poorly understood." | 2.52 | Systemic review: the pathogenesis and pharmacological treatment of hiccups. ( Fox, M; Schneemann, M; Steger, M, 2015) |
| "Persistent hiccups have been reported to occur occasionally during rehabilitation hospitalizations." | 2.44 | Persistent hiccups during rehabilitation hospitalization: three case reports and review of the literature. ( Browne, BA; Schuchmann, JA, 2007) |
| "Hiccups are a common phenomenon but little is known about their pathophysiological mechanism or function." | 2.43 | [Hiccups]. ( ten Holter, JB, 2005) |
| "Hiccups occur in 15-40% of cancer patients, but previous research has not sought the perspectives of cancer healthcare providers." | 1.91 | Healthcare Providers' Experiences with Hiccups in Patients with Cancer: Report of a United States National Survey. ( Jatoi, A; Martin, N; Wieland, J, 2023) |
| "Chlorpromazine is a known treatment option for hiccups, but its efficacy under general anesthesia remains unclear." | 1.72 | Effective Treatment of Intraoperative Hiccups With Chlorpromazine Under General Anesthesia Without Muscle Relaxants: A Case Report. ( Inokuchi, R; Ishitsuka, S; Shimada, K; Tominaga, K; Yagihashi, S; Yamada, M, 2022) |
| "Chlorpromazine was the first choice treatment in 23 patients, but seven required a second line drug." | 1.34 | [Hiccup: review of 24 cases]. ( Martínez Rey, C; Villamil Cajoto, I, 2007) |
| "Hiccup is a brief involuntary inspiratory movement followed by glottal closure." | 1.30 | [Diabolic hiccup]. ( Heick, A, 1997) |
| "Treatment with carbamazepine was successful in only one patient; in the other two subjects, their hiccups were controlled with haloperidol or baclofen." | 1.30 | Intractable hiccups during stroke rehabilitation. ( Dromerick, AW; Kumar, A, 1998) |
| "It stopped hiccough in five of seven patients treated and partially controlled it in the other two." | 1.23 | Emesis and hiccough; treatment with chlorpromazine. ( REDEKER, AG; STEWART, BL, 1954) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (39.02) | 18.7374 |
| 1990's | 6 (14.63) | 18.2507 |
| 2000's | 7 (17.07) | 29.6817 |
| 2010's | 6 (14.63) | 24.3611 |
| 2020's | 6 (14.63) | 2.80 |
| Authors | Studies |
|---|---|
| Shimada, K | 1 |
| Inokuchi, R | 1 |
| Tominaga, K | 1 |
| Yagihashi, S | 1 |
| Yamada, M | 1 |
| Ishitsuka, S | 1 |
| Wang, J | 1 |
| Zhu, Q | 1 |
| Zhang, S | 1 |
| Wen, L | 1 |
| Wang, L | 1 |
| Wieland, J | 1 |
| Martin, N | 1 |
| Jatoi, A | 1 |
| Lambert, D | 1 |
| Nothem, ME | 1 |
| Kobylarz, Z | 1 |
| Scholcoff, C | 1 |
| Dorgalaleh, A | 1 |
| Dabbagh, A | 1 |
| Tabibian, S | 1 |
| Bahraini, M | 1 |
| Rafieemehr, H | 1 |
| Ikitimur, H | 1 |
| Borku Uysal, B | 1 |
| Ikitimur, B | 1 |
| Umihanic, S | 1 |
| Smajic, J | 1 |
| Jahic, R | 1 |
| Olcay, A | 1 |
| Polito, NB | 1 |
| Fellows, SE | 1 |
| Zhang, SK | 1 |
| Gao, WB | 1 |
| Liu, Y | 1 |
| He, H | 1 |
| Yehl, JL | 1 |
| Sheyner, I | 1 |
| Fasnacht, KS | 1 |
| Stewart, JT | 1 |
| Steger, M | 1 |
| Schneemann, M | 1 |
| Fox, M | 1 |
| de Arriba Méndez, JJ | 1 |
| Gardecki, J | 1 |
| Espinosa, J | 1 |
| Lucerna, A | 1 |
| Bernhardt, J | 1 |
| Van Damme, PA | 1 |
| Ju, L | 1 |
| STEWART, BL | 1 |
| REDEKER, AG | 1 |
| FRIEDGOOD, CE | 1 |
| RIPSTEIN, CB | 1 |
| MOYER, JH | 1 |
| KINROSS-WRIGHT, V | 1 |
| FINNEY, RM | 1 |
| PARIS RUIZ, L | 1 |
| GARIPUY, A | 1 |
| RAYMOND, M | 1 |
| GUIANG, RV | 1 |
| LEONES-GUIANG, MA | 1 |
| HARNIK, E | 1 |
| DAVIGNON, A | 1 |
| LEMIEUX, G | 1 |
| GENEST, J | 1 |
| Nguyen, JD | 1 |
| Dunleavy, K | 1 |
| Carrasquillo, JA | 1 |
| Chen, CC | 1 |
| ten Holter, JB | 1 |
| Minondo Amuchasteguia, L | 1 |
| Egiguren Urrosolo, L | 1 |
| Zapata Morcillo, E | 1 |
| Castiella Eguzkiza, A | 1 |
| Martínez Rey, C | 1 |
| Villamil Cajoto, I | 1 |
| Schuchmann, JA | 1 |
| Browne, BA | 1 |
| Oshima, T | 1 |
| Sakamoto, M | 1 |
| Arita, H | 1 |
| Galofré, N | 1 |
| Arnau, MD | 1 |
| Campodarve, I | 1 |
| Peña, MJ | 1 |
| Schneider, JM | 1 |
| Roger, DJ | 1 |
| Uhl, RL | 1 |
| Heick, A | 1 |
| Kumar, A | 1 |
| Dromerick, AW | 1 |
| Williamson, BW | 1 |
| MacIntyre, IM | 1 |
| Fry, EN | 1 |
| Howard, RS | 1 |
| Bach, N | 1 |
| Thung, SN | 1 |
| Schaffner, F | 1 |
| Tobias, H | 1 |
| Lewis, JH | 1 |
| Kounis, NG | 1 |
| Brendel, B | 1 |
| Ikram, H | 1 |
| Orchard, RT | 1 |
| Read, SE | 1 |
6 reviews available for chlorpromazine and Hiccough
| Article | Year |
|---|---|
Pharmacologic Interventions for Intractable and Persistent Hiccups: A Systematic Review.
Topics: Adrenergic Uptake Inhibitors; Chlorpromazine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists | 2017 |
Systemic review: the pathogenesis and pharmacological treatment of hiccups.
Topics: Amines; Anticonvulsants; Antipsychotic Agents; Baclofen; Benzamides; Chlorpromazine; Cyclohexanecarb | 2015 |
[Dexamethasone-induced hiccup].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chlorpromazine; Dex | 2016 |
[Hiccups].
Topics: Baclofen; Chlorpromazine; Hiccup; Humans; Muscle Relaxants, Central; Piracetam | 2005 |
Persistent hiccups during rehabilitation hospitalization: three case reports and review of the literature.
Topics: Aged; Amines; Anti-Anxiety Agents; Anticonvulsants; Cerebral Infarction; Chlorpromazine; Chronic Dis | 2007 |
Hiccups: causes and cures.
Topics: Abdomen; Alcohol Drinking; Anticonvulsants; Central Nervous System Stimulants; Chlorpromazine; Hiccu | 1985 |
1 trial available for chlorpromazine and Hiccough
| Article | Year |
|---|---|
[Therapeutic effect of cervical Jiaji electroacupuncture on postoperative intractable hiccup of liver neoplasms].
Topics: Acupuncture Points; Antiemetics; Chlorpromazine; Drug Therapy, Combination; Electroacupuncture; Hicc | 2018 |
34 other studies available for chlorpromazine and Hiccough
| Article | Year |
|---|---|
Effective Treatment of Intraoperative Hiccups With Chlorpromazine Under General Anesthesia Without Muscle Relaxants: A Case Report.
Topics: Anesthesia, General; Chlorpromazine; Hiccup; Humans; Muscles; Treatment Outcome | 2022 |
Observation of Clinical Efficacy of Anisodamine and Chlorpromazine in the Treatment of Intractable Hiccup after Stroke.
Topics: Algorithms; Chlorpromazine; Hiccup; Humans; Solanaceous Alkaloids; Stroke; Treatment Outcome | 2022 |
Healthcare Providers' Experiences with Hiccups in Patients with Cancer: Report of a United States National Survey.
Topics: Baclofen; Chlorpromazine; Hiccup; Humans; Neoplasms; United States | 2023 |
A Medication Hiccup: Chlorpromazine-Induced Agranulocytosis in a 72-Year-Old Male.
Topics: Aged; Agranulocytosis; Chlorpromazine; Hiccup; Humans; Male; Sepsis | 2022 |
Persistent hiccups in a patient with mild congenital factor V deficiency and COVID-19; clinical and laboratory finding of a rare bleeding disorder.
Topics: Chlorpromazine; COVID-19; COVID-19 Drug Treatment; Factor V Deficiency; Hematologic Tests; Hemorrhag | 2021 |
Case Report: Two Cases of Persistent Hiccups Complicating COVID-19.
Topics: Aged; Chlorpromazine; COVID-19; Hiccup; Humans; Male; Middle Aged; SARS-CoV-2 | 2021 |
A case of tardive dyskinesia in the last weeks of life.
Topics: Anti-Dyskinesia Agents; Chlorpromazine; Haloperidol; Hiccup; Hospice Care; Humans; Male; Middle Aged | 2015 |
Singultus: Avoiding a hiccup in care.
Topics: Chlorpromazine; Electrocardiography; Hiccup; Humans; Hypokalemia; Hyponatremia; Male; Middle Aged; P | 2017 |
Post operative hiccups.
Topics: Chlorpromazine; Chronic Disease; Dopamine Antagonists; Hiccup; Humans; Postoperative Complications | 2008 |
Twenty-five cases of obstinate hiccup treated by point injection at tianding.
Topics: Acupuncture Points; Adolescent; Adult; Aged; Chlorpromazine; Female; Hiccup; Humans; Injections; Mal | 2003 |
Emesis and hiccough; treatment with chlorpromazine.
Topics: Chlorpromazine; Hiccup; Humans; Injections, Intramuscular; Vomiting | 1954 |
Chlorpromazine (thorazine) in the treatment of intractable hiccups.
Topics: Chlorpromazine; Hiccup; Humans | 1955 |
Chlorpromazine as a therapeutic agent in clinical medicine.
Topics: Chlorpromazine; Electroconvulsive Therapy; Hiccup; Mental Disorders; Psychosurgery; Psychotherapy; V | 1955 |
[Therapeutic uses of chlorpromazine (largactil)].
Topics: Alcoholism; Anesthesia; Chlorpromazine; Hiccup; Humans; Vomiting | 1955 |
[Incoercible hiccups and autonomic drugs].
Topics: Autonomic Agents; Chlorpromazine; Hiccup; Humans | 1956 |
Intractable hiccups in subarachnoid hemorrhage relieved by chlorpromazine.
Topics: Chlorpromazine; Hiccup; Humans; Subarachnoid Hemorrhage | 1957 |
A STUDY OF THE BIPHASIC VENTILATORY EFFECTS OF PROPANIDID.
Topics: Adolescent; Anesthetics; Apnea; Atropine; Child; Chlorpromazine; Geriatrics; Hiccup; Humans; Meperid | 1964 |
[Chlorpromazine in the treatment of stubborn hiccup].
Topics: Chlorpromazine; Hiccup; Humans; Mental Disorders | 1955 |
F-18 fluorodeoxyglucose positron emission tomographic imaging in a patient with persistent hiccups.
Topics: Baclofen; Brain; Brain Neoplasms; Chlorpromazine; Diagnosis, Differential; Fluorodeoxyglucose F18; H | 2004 |
[Chlorpromazine-induced cholestatic hepatitis in intractable hiccups].
Topics: Aged; Antipsychotic Agents; Bile Duct Diseases; Chemical and Drug Induced Liver Injury; Chlorpromazi | 2007 |
[Hiccup: review of 24 cases].
Topics: Adrenal Cortex Hormones; Aged; Aged, 80 and over; Benzodiazepines; Chlorpromazine; Digestive System | 2007 |
Hiccuplike response elicited by mechanical stimulation of dorsal epipharynx of cats.
Topics: Animals; Carbon Dioxide; Cats; Chlorpromazine; Diaphragm; Electric Stimulation; Electrodes, Implante | 1994 |
[Thrombocytopenia secondary to treatment with chlorpromazine].
Topics: Boutonneuse Fever; Cerebral Infarction; Chlorpromazine; Hiccup; Humans; Male; Middle Aged; Thrombocy | 1993 |
Bilateral forearm compartment syndromes resulting from neuroleptic malignant syndrome.
Topics: Angioplasty, Balloon, Coronary; Antipsychotic Agents; Chlorpromazine; Compartment Syndromes; Coronar | 1996 |
[Diabolic hiccup].
Topics: Baclofen; Brain Stem; Calcium Channel Blockers; Chlorpromazine; Dopamine Antagonists; GABA Agents; H | 1997 |
Intractable hiccups during stroke rehabilitation.
Topics: Aged; Baclofen; Carbamazepine; Cerebral Infarction; Cerebrovascular Disorders; Chlorpromazine; Dopam | 1998 |
Management of intractable hiccup.
Topics: Adult; Chlorpromazine; Hiccup; Humans; Male; Metoclopramide; Nerve Crush; Phrenic Nerve | 1977 |
Management of intractable hiccup.
Topics: Chlorpromazine; Hiccup; Humans; Methamphetamine; Pentazocine | 1977 |
Persistent hiccups.
Topics: Chlorpromazine; Chronic Disease; Hiccup; Humans | 1992 |
Exaggerated cholestasis and hepatic fibrosis following simultaneous administration of chlorpromazine and sodium valproate.
Topics: Chlorpromazine; Cholestasis; Drug Interactions; Hiccup; Humans; Liver Cirrhosis; Male; Middle Aged; | 1989 |
Persistent hiccuping in acute myocardial infarction--report of a case.
Topics: Aged; Chlorpromazine; Hiccup; Humans; Male; Myocardial Infarction; Prognosis | 1974 |
[Causes of occurrence and current methods in the treatment of postoperative hiccups].
Topics: Adult; Aged; Anesthesia, General; Atropine; Chlorpromazine; Female; Hiccup; Humans; Male; Middle Age | 1969 |
Hiccup.
Topics: Amides; Amitriptyline; Benzoates; Catheterization; Chlorpromazine; Digestive System; Hiccup; Humans; | 1971 |
Intractable hiccuping in acute myocardial infarction.
Topics: Acute Disease; Aged; Chlorpromazine; Hiccup; Humans; Injections, Intramuscular; Lidocaine; Male; Myo | 1971 |