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chlorpromazine and Hemolysis

chlorpromazine has been researched along with Hemolysis in 114 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Hemolysis: The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.

Research Excerpts

ExcerptRelevanceReference
"Influence of divalent Ca2+ ions in sulphonated chlorophthalocyanine (ClAlPcS2) induced photohemolysis in rabbit red blood cells has been investigated."7.70Effects of calcium on phthalocyanine sensitized photohemolysis. ( Jain, V; Varshney, R, 1998)
"Sendai virus-induced hemolysis, a manifestation of virus-red cell fusion, is inhibited by exposure of the virus to 50 microM and higher concentrations of trifluoperazine."7.67Trifluoperazine inhibits Sendai virus-induced hemolysis. ( MacDonald, RI, 1986)
"Influence of divalent Ca2+ ions in sulphonated chlorophthalocyanine (ClAlPcS2) induced photohemolysis in rabbit red blood cells has been investigated."3.70Effects of calcium on phthalocyanine sensitized photohemolysis. ( Jain, V; Varshney, R, 1998)
"Since amphiphilic drugs are known to interact with biomembranes, we investigated local vessel damage and thrombosis which might be brought about by intravenous dosing using chlorpromazine (CPZ) as a representative compound."3.70Local thrombus formation in the site of intravenous injection of chlorpromazine: possible colloid-osmotic lysis of the local endothelial cells. ( Kanamaru, H; Kaneko, H; Nishibe, H; Tani, N; Yabuki, M; Yoshioka, T, 2000)
" The kinetic studies in isotonic suspensions of erythrocytes indicated that the hemolysis induced by the amphipathic drug chlorpromazine (CPZ) or flufenamic acid (FA) was retarded by addition of sugars, and the degree of the anti-hemolytic effect increased with increases in molecular size."3.69Protective effects of neutral amino acids against amphipathic drug-induced hemolysis. ( Iida, T; Kado, Y; Morimoto, Y; Shiota, M; Takeuchi, Y; Yutani, Y, 1995)
"By a photohemolysis test we assessed in vitro the phototoxic properties of 12 phenothiazines (chlorpromazine, dixyrazine, fluphenazine, levomepromazine, perazine, perphenazine, promazine, promethazine, prothipendyl, thioridazine, trifluoperazine, triflupromazine) and 5 thioxanthenes (chlorprothixene, clopenthixol, flupenthixol, thiothixene, zuclopenthixol)."3.69Phototoxic properties of neuroleptic drugs. ( Bindl, A; Eberlein-König, B; Przybilla, B, 1997)
" In the present study, we determined that, in fact, cyclodextrin polysulfate (CDS) actively protected erythrocytes against hemolysis induced by a wide spectrum of hemolytically active substances, ranging from pharmaceuticals, such as chlorpromazine, to solid suspensions of siliceous particles."3.68Protection of erythrocytes against hemolytic agents by cyclodextrin polysulfate. ( Kumor, K; Macarak, EJ; Weisz, PB, 1993)
"Hemolysis experiments indicated that glycine (20 mM) remarkably suppressed the chlorpromazine (CPZ)-induced osmotic permeability enhancing effect in rabbit erythrocytes."3.67Stabilizing effects of some amino acids on membranes of rabbit erythrocytes perturbed by chlorpromazine. ( Fukuda, T; Fukumori, Y; Kaneko, I; Morimoto, Y; Takeuchi, Y; Yamaoka, Y, 1989)
"Sendai virus-induced hemolysis, a manifestation of virus-red cell fusion, is inhibited by exposure of the virus to 50 microM and higher concentrations of trifluoperazine."3.67Trifluoperazine inhibits Sendai virus-induced hemolysis. ( MacDonald, RI, 1986)
" The heat produced in erythrocyte hemolysis induced by chlorpromazine hydrochloride (CPZ) and the binding heat of CPZ to human blood components viz."3.67Application of differential flow microcalorimetry for study of drug interactions in the blood system. ( Aki, H; Yamamoto, M, 1988)
"beta-Cyclodextrin (beta-CyD) significantly protected the human erythrocytes from hemolysis and shape changes induced with chlorpromazine and flufenamic acid in isotonic solution."3.66Protective effects of cyclodextrins on drug-induced hemolysis in vitro. ( Irie, T; Otagiri, M; Sunada, M; Tsubaki, K; Uekama, K, 1981)
"The hemolysis of human red cells in the presence of chlorpromazine and 2-methylpropanal, or propanal, has been studied by a spectrophotometric method."3.66Synergistic effect of chlorpromazine and alkanals on the human red blood cells. ( Durán, N; Haun, M; Makita, Y; Vercesi, AE, 1981)
" Acute CPZ treatment (25 mg per kg intravenously) produced hemolysis and resulted in increased bilirubin output and stimulation of hepatic heme synthesis."3.65Effects of chlorpromazine on bilirubin metabolism and biliary secretion in the rat. ( Knodell, RG, 1975)
"Photohemolysis is an accurate tool for demonstrating DMCT phototoxicity."1.27Studies on photohemolysis with special reference to demethylchlortetracycline. ( Bjellerup, M; Ljunggren, B, 1984)
"The chlorpromazine-induced lysis was markedly enhanced by thrombin and phorbol ester, and complete cytolysis was found at chlorpromazine concentrations of 100 microM and above in the presence of thrombin."1.27Differential effects of chlorpromazine on secretion, protein phosphorylation and phosphoinositide metabolism in stimulated platelets. ( Aarsaether, N; Holmsen, H; Lillehaug, JR; Opstvedt, A; Rongved, S, 1986)
" The results of this study suggest that the in vitro tests employed can be useful as screening tests for local toxic effect of intramuscular drug preparations."1.27Tests for local toxicity of intramuscular drug preparations: comparison of in vivo and in vitro methods. ( Bagdon, RE; Højelse, F; Svendsen, O, 1985)

Research

Studies (114)

TimeframeStudies, this research(%)All Research%
pre-199097 (85.09)18.7374
1990's13 (11.40)18.2507
2000's3 (2.63)29.6817
2010's1 (0.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Favretto, ME1
Cluitmans, JC1
Bosman, GJ1
Brock, R1
LINDBERG, LG1
NORDEN, A1
HARRISON, GA1
ROSEN, M1
GOODALL, P1
KATZ, R1
VELASCO, M1
GUZMAN, C1
ALESSANDRI, H1
Abajo, C1
Boffill, MA1
del Campo, J1
Alexandra Méndez, M1
González, Y1
Mitjans, M1
Pilar Vinardell, M1
Mao, TS2
Noval, JJ2
Becker, GA1
Pisciotta, AV1
van Steveninck, J2
Gjösũnd, WK1
Booij, HL1
Saunders, DM1
Minetti, M1
Ceccarini, M1
Di Stasi, AM1
Born, GV8
Görög, P1
Kratzer, MA1
Uekama, K3
Irie, T3
Sunada, M2
Otagiri, M2
Iwasaki, K1
Okano, Y1
Miyata, T1
Kasé, Y1
Panijpan, B1
Kantakanit, N1
Housley, GM2
Baba, Y1
Nakao, Y1
Kishihara, M1
Kobayashi, N1
Kimoto, H1
Matsukura, S1
Fujita, T1
Kuma, K1
Bjellerup, M2
Ljunggren, B2
Janoff, AS1
Mazorow, DL1
Coughlin, RT1
Bowdler, AJ1
Haug, A1
McGroarty, EJ1
Mishra, KP2
Binh, LD1
Singh, BB2
Möller, H1
Beresford, RA1
Fastier, FN1
Rao, MN1
Bhise, SB1
Srivastava, RC1
Lieber, MR2
Lange, Y1
Weinstein, RS1
Steck, TL2
Kochevar, IE2
Hom, J1
Smith, JE1
Mohandas, N1
Clark, MR1
Greenquist, AC1
Shohet, SB1
Wehmeier, A2
Tsubaki, K1
Srinivasan, VT1
Makita, Y2
Vercesi, AE1
Haun, M1
Durán, N2
Shiotani, K1
Uehata, K1
Hirayama, F1
Thompson, AA1
Cornelius, AS1
Asakura, T1
Horiuchi, K1
Yamaguchi, T1
Matsumoto, M1
Kimoto, E1
Weisz, PB1
Kumor, K1
Macarak, EJ1
Shpakova, NM2
Pantaler, ER1
Bondarenko, VA2
Babu, AS1
Gowda, TV1
Morimoto, Y2
Yutani, Y1
Kado, Y1
Iida, T1
Shiota, M1
Takeuchi, Y2
Rudenko, SV1
Nipot, EE1
Eberlein-König, B1
Bindl, A1
Przybilla, B1
Varshney, R1
Jain, V1
Hägerstrand, H1
Danieluk, M1
Bobrowska-Hägerstrand, M1
Iglic, A1
Wróbel, A1
Isomaa, B1
Nikinmaa, M1
Yabuki, M1
Tani, N1
Yoshioka, T1
Nishibe, H1
Kanamaru, H1
Kaneko, H1
Ansel, HC2
Gigandet, MP2
Terhaag, B1
Bockisch, A1
Baadenhuijsen, H1
Seuren-Jacobs, HE1
Jansen, AP1
Esser, AF1
Kobayashi, R1
Tawata, M1
Hidaka, H1
Schubothe, H1
Maas, D1
Weber, S1
Lamola, AA1
Loyter, A1
Gazitt, Y1
Ohad, I1
Kristiansen, JE1
Elfernik, JG1
Bergqvist, D1
Arfors, KE1
Ogiso, T1
Masuda, H1
Oue, S1
Nilsson, R1
Swanbeck, G2
Wennersten, G2
Sheetz, MP2
Painter, RG1
Singer, SJ2
Berg, KJ1
Bergan, A1
Lovrien, R1
Tisel, W1
Pesheck, P1
Knodell, RG1
Miller, FN1
Tangelder, GJ1
Slaaf, DW1
Reneman, RS1
Robertson, DG1
Bailey, DL1
Martin, RA1
Yamaoka, Y1
Kaneko, I1
Fukumori, Y1
Fukuda, T1
Gonçalves, ML1
Ribeiro, JA1
Rosso, J1
Zachowski, A1
Devaux, PF1
Housley, G1
Conroy, DM1
Belin, J1
Smith, AD1
Lagercrantz, C1
Larsson, T1
Tollsten, L1
Prus, K1
MacDonald, RI1
Opstvedt, A1
Rongved, S1
Aarsaether, N1
Lillehaug, JR1
Holmsen, H1
Yamamoto, M1
Aki, H1
Gemba, M1
Ushijima, H1
Nakajima, M1
Nakano, S1
Svendsen, O1
Højelse, F1
Bagdon, RE1
Mircevová, L1
Simonová, A1
Tanaka, K1
Kobayashi, K1
Kazui, S1
Olaisen, B1
Oye, I1
Ferber, E1
Munder, PG1
Kohlschütter, A1
Fischer, H1
Baur, EW2
Zingales, IA1
Fievet, CJ1
Johnson, BE1
Santos-Martinez, J1
Aviles, TA1
Laboy-Torres, JA1
Kahn, G2
Curry, MC2
Dustin, R1
Fleck, W1
Krieglstein, J1
Urban, W1
Bube, FW1
Aloni, B1
Livne, A1
Popov, CS2
Seeman, P6
Machleidt, H1
Kähling, J1
Sengupta, S1
Kwant, WO4
Sauks, T2
Ahtee, L2
Paasonen, MK1
Roth, S2
Bube, F1
Sehrbundt, M1
Sheppard, H1
Tsien, WH1
Burghardt, C1
Mikikits, W1
Mortara, A1
Spector, RG1
Yordanov, IM1
Nikiforova, MN1
Langslet, A1
Preston, FE1
Lee, D1
Laforet, MT1
Gardner, FH1
Lee, IP1
Yamamura, HI1
Dixon, RL1
Argent, W1
Lideman, RR1
Ir'ianov, IuI1

Reviews

1 review available for chlorpromazine and Hemolysis

ArticleYear
[Drug induced immune hemolytic anemia].
    Haematology and blood transfusion, 1978, Volume: 21

    Topics: Anemia, Hemolytic; Anemia, Hemolytic, Autoimmune; Antibody Formation; Antigen-Antibody Complex; Auto

1978

Other Studies

113 other studies available for chlorpromazine and Hemolysis

ArticleYear
Human erythrocytes as drug carriers: loading efficiency and side effects of hypotonic dialysis, chlorpromazine treatment and fusion with liposomes.
    Journal of controlled release : official journal of the Controlled Release Society, 2013, Sep-28, Volume: 170, Issue:3

    Topics: Antipsychotic Agents; beta-Galactosidase; Chlorpromazine; Dialysis; Drug Carriers; Erythrocytes; Flu

2013
Severe hemolytic reaction to chlorpromazine.
    Acta medica Scandinavica, 1961, Volume: 170

    Topics: Anemia, Hemolytic; Chlorpromazine; Hemolysis; Humans; Jaundice

1961
HAEMORRHAGIC COMPLICATIONS DURING THE TREATMENT OF TETANUS.
    Lancet (London, England), 1964, Feb-29, Volume: 1, Issue:7331

    Topics: Amobarbital; Child; Chloramphenicol; Chlorpromazine; Diphenhydramine; Hematuria; Hemolysis; Hydrocor

1964
RED CELL SURVIVAL ESTIMATED BY RADIOACTIVE CHROMIUM IN HEPATOBILIARY DISEASE.
    Gastroenterology, 1964, Volume: 46

    Topics: Alcoholism; Bilirubin; Blood Chemical Analysis; Cell Survival; Chlorpromazine; Chromium; Chromium Is

1964
In vitro study of the antioxidant and immunomodulatory activity of aqueous infusion of Bidens pilosa.
    Journal of ethnopharmacology, 2004, Volume: 93, Issue:2-3

    Topics: Adjuvants, Immunologic; Amidines; Antioxidants; Bidens; Chlorpromazine; Hemolysis; Humans; Leukocyte

2004
Some relationships concerning the chemical structure, hemolytic activity, and therapeutic potency of phenothiazines.
    Biochemical pharmacology, 1966, Volume: 15, Issue:4

    Topics: Animals; Cell Membrane Permeability; Chemical Phenomena; Chemistry; Chlorpromazine; Erythrocytes; Fl

1966
Potentiation of hemolytic plaque formation by incubation of immunized spleen cells in phenothiazine derivatives.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1967, Volume: 124, Issue:3

    Topics: Animals; Antibody Formation; Cell Membrane Permeability; Chlorpromazine; Erythrocytes; Hemolysin Pro

1967
The influence of chlorpromazine on the osmotic fragility of erythrocytes.
    Biochemical pharmacology, 1967, Volume: 16, Issue:5

    Topics: Animals; Cattle; Chlorpromazine; Erythrocyte Count; Erythrocytes; Hemolysis; Humans; Osmotic Fragili

1967
Classical eclampsia with acute intravascular haemolysis.
    The Medical journal of Australia, 1967, Sep-23, Volume: 2, Issue:13

    Topics: Adult; Anemia, Hemolytic; Australia; Blood Chemical Analysis; Blood Platelet Disorders; Chlorpromazi

1967
Role of membrane thermotropic properties on hypotonic hemolysis and hypertonic cryohemolysis of human red blood cells.
    Journal of cellular biochemistry, 1984, Volume: 25, Issue:2

    Topics: Chlorpromazine; Chymotrypsin; Cold Temperature; Electron Spin Resonance Spectroscopy; Erythrocyte Me

1984
Aggregation of platelets in damaged vessels.
    Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 1981, Aug-18, Volume: 294, Issue:1072

    Topics: Adenosine Diphosphate; Animals; Arteries; Arteriosclerosis; Blood Platelets; Chlorpromazine; Collage

1981
Effects of cyclodextrins on chlorpromazine-induced haemolysis and central nervous system responses.
    The Journal of pharmacy and pharmacology, 1981, Volume: 33, Issue:11

    Topics: Animals; Central Nervous System; Chlorpromazine; Cyclodextrins; Dextrins; Drug Interactions; Erythro

1981
Chlorpromazine enhances haemolysis induced by haemin.
    The Journal of pharmacy and pharmacology, 1983, Volume: 35, Issue:7

    Topics: Animals; Chlorpromazine; Diet; Erythrocytes; Heme; Hemin; Hemoglobins; Hemolysis; Humans; In Vitro T

1983
Influence of charge and molecular size on membrane stabilization.
    Proceedings of the Royal Society of London. Series B, Biological sciences, 1983, Aug-22, Volume: 219, Issue:1214

    Topics: Amines; Chlorpromazine; Erythrocyte Membrane; Hemolysis; Humans; Osmotic Fragility; Structure-Activi

1983
Effect of various drugs on the binding of thyrotrophin to thyroid plasma membranes.
    Acta endocrinologica, 1982, Volume: 100, Issue:4

    Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Anesthetics, Local; Anti-Arrhythmia Agents; Aprotini

1982
Studies on photohemolysis with special reference to demethylchlortetracycline.
    Acta dermato-venereologica, 1984, Volume: 64, Issue:5

    Topics: Chlorpromazine; Demeclocycline; Dose-Response Relationship, Radiation; Ferricyanides; Hemoglobins; H

1984
The modification of human erythrocyte membrane structure by membrane stabilizers: an electron spin resonance study.
    American journal of hematology, 1981, Volume: 10, Issue:2

    Topics: Chlorpromazine; Diazepam; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Erythrocytes;

1981
Effect of dielectric discharge on drug treated mammalian cells.
    Indian journal of experimental biology, 1981, Volume: 19, Issue:6

    Topics: Animals; Chlorpromazine; Electric Stimulation; Erythrocytes; Erythrosine; Fluoresceins; Hemolysis; L

1981
Experimental studies on the mechanism of benoxaprofen photoreactions.
    Archives of dermatological research, 1983, Volume: 275, Issue:5

    Topics: Animals; Candida albicans; Chlorpromazine; Female; Hemolysis; Humans; In Vitro Techniques; Mice; Pho

1983
Effects of some S-alkylthiouroniums and related compounds on the osmotic fragility and the membrane expansion of human erythrocytes.
    British journal of pharmacology, 1980, Volume: 71, Issue:1

    Topics: Chlorpromazine; Erythrocyte Membrane; Erythrocytes; Hemolysis; Humans; In Vitro Techniques; Osmotic

1980
Antihemolytic action of surface active drugs.
    Indian journal of experimental biology, 1984, Volume: 22, Issue:4

    Topics: Animals; Chlorpromazine; Dextropropoxyphene; Dibucaine; Goats; Hemolysis; Hypotonic Solutions; Phosp

1984
Effects of modification of the membranes of intact erythrocytes on the anti-haemolytic action of chlorpromazine.
    British journal of pharmacology, 1983, Volume: 79, Issue:2

    Topics: Chlorpromazine; Erythrocyte Membrane; Hemolysis; Humans; Membrane Lipids; Neuraminidase; Sialic Acid

1983
Interaction of chlorpromazine with the human erythrocyte membrane.
    The Journal of biological chemistry, 1984, Jul-25, Volume: 259, Issue:14

    Topics: Biological Transport; Chlorpromazine; Erythrocyte Membrane; Freeze Fracturing; Hemolysis; Humans; Ki

1984
Dynamics of the holes in human erythrocyte membrane ghosts.
    The Journal of biological chemistry, 1982, Oct-10, Volume: 257, Issue:19

    Topics: Chlorpromazine; Cholesterol; Erythrocyte Membrane; Erythrocytes; Glutaral; Hemolysis; Humans; Kineti

1982
Photoproducts of chlorpromazine which cause red blood cell lysis.
    Photochemistry and photobiology, 1983, Volume: 37, Issue:2

    Topics: Chlorpromazine; Erythrocytes; Hemolysis; Humans; Photolysis

1983
Deformability and spectrin properties in three types of elongated red cells.
    American journal of hematology, 1980, Volume: 8, Issue:1

    Topics: Anemia, Sickle Cell; Animals; Camelids, New World; Chlorpromazine; Erythrocytes; Hemolysis; Humans;

1980
Possible approaches to the pharmacological prevention of myocardial ischaemia.
    Acta medica Scandinavica. Supplementum, 1980, Volume: 642

    Topics: Arteriosclerosis; Blood Platelets; Blood Vessels; Chlorpromazine; Coronary Disease; Hemolysis; Human

1980
Protective effects of cyclodextrins on drug-induced hemolysis in vitro.
    Journal of pharmacobio-dynamics, 1981, Volume: 4, Issue:2

    Topics: Chlorpromazine; Cyclodextrins; Dextrins; Erythrocytes; Flufenamic Acid; Hemolysis; Humans; In Vitro

1981
Interaction between chlorpromazine and radiation damage to human erythrocyte membrane.
    Radiation research, 1981, Volume: 88, Issue:2

    Topics: Chlorpromazine; Erythrocyte Membrane; Erythrocytes; Gamma Rays; Hemolysis; Humans; Osmotic Fragility

1981
Synergistic effect of chlorpromazine and alkanals on the human red blood cells.
    Anais da Academia Brasileira de Ciencias, 1981, Volume: 53, Issue:4

    Topics: Acetaldehyde; Aldehydes; Chlorpromazine; Drug Synergism; Energy Transfer; Erythrocytes; Hemolysis; H

1981
Characterization of the inclusion mode of beta-cyclodextrin sulfate and its effect on the chlorpromazine-induced hemolysis of rabbit erythrocytes.
    Chemical & pharmaceutical bulletin, 1994, Volume: 42, Issue:11

    Topics: Animals; beta-Cyclodextrins; Cells, Cultured; Chemistry, Pharmaceutical; Chlorpromazine; Cyclodextri

1994
Comparative studies of phenothiazine derivatives for their effects on swelling of normal and sickle erythrocytes.
    General pharmacology, 1993, Volume: 24, Issue:4

    Topics: Adult; Anemia, Sickle Cell; Antipsychotic Agents; Antisickling Agents; Calmodulin; Chlorpromazine; E

1993
Hemolytic properties under hydrostatic pressure of neuraminidase- or protease-treated human erythrocytes.
    Journal of biochemistry, 1993, Volume: 114, Issue:4

    Topics: Chlorpromazine; Cross-Linking Reagents; Diamide; Endopeptidases; Erythrocyte Membrane; Glycopeptides

1993
Protection of erythrocytes against hemolytic agents by cyclodextrin polysulfate.
    Biochemical pharmacology, 1993, Mar-09, Volume: 45, Issue:5

    Topics: Cells, Cultured; Chlorpromazine; Cyclodextrins; Drug Antagonism; Erythrocytes; Hemolysis; Humans; Su

1993
[Antihemolytic effect of chlorpromazine on erythrocytes in hyperosmotic and cold shock].
    Biokhimiia (Moscow, Russia), 1995, Volume: 60, Issue:10

    Topics: Chlorpromazine; Cold Temperature; Hemolysis; Humans; In Vitro Techniques; Osmolar Concentration; Wat

1995
Effects of chlorpromazine on the enzymatic and toxic properties of the most basic phospholipase A2 from Vipera russelli snake venom.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1995, Volume: 44, Issue:8

    Topics: Animals; Anticoagulants; Chlorpromazine; Edema; Hemolysis; L-Lactate Dehydrogenase; Lethal Dose 50;

1995
Protective effects of neutral amino acids against amphipathic drug-induced hemolysis.
    Biological & pharmaceutical bulletin, 1995, Volume: 18, Issue:11

    Topics: Amino Acids; Animals; Carbohydrates; Chlorpromazine; Erythrocytes; Flufenamic Acid; Hemolysis; In Vi

1995
Protection by chlorpromazine, albumin and bivalent cations against haemolysis induced by melittin, [Ala-14]melittin and whole bee venom.
    The Biochemical journal, 1996, Aug-01, Volume: 317 ( Pt 3)

    Topics: Albumins; Bee Venoms; Calcium; Cations, Divalent; Cell Size; Chlorpromazine; Erythrocyte Membrane; H

1996
Phototoxic properties of neuroleptic drugs.
    Dermatology (Basel, Switzerland), 1997, Volume: 194, Issue:2

    Topics: Antipsychotic Agents; Chlorpromazine; Chlorprothixene; Clopenthixol; Dermatitis, Phototoxic; Drug Er

1997
Effects of calcium on phthalocyanine sensitized photohemolysis.
    Indian journal of experimental biology, 1998, Volume: 36, Issue:2

    Topics: Animals; Calcium; Calcium Channel Blockers; Chlorpromazine; Egtazic Acid; Erythrocytes; Hemolysis; I

1998
Influence of band 3 protein absence and skeletal structures on amphiphile- and Ca(2+)-induced shape alterations in erythrocytes: a study with lamprey (Lampetra fluviatilis), trout (Onchorhynchus mykiss) and human erythrocytes.
    Biochimica et biophysica acta, 2000, Jun-01, Volume: 1466, Issue:1-2

    Topics: Abietanes; Animals; Anion Exchange Protein 1, Erythrocyte; Calcimycin; Calcium; Carboxylic Acids; Ce

2000
Local thrombus formation in the site of intravenous injection of chlorpromazine: possible colloid-osmotic lysis of the local endothelial cells.
    Biological & pharmaceutical bulletin, 2000, Volume: 23, Issue:8

    Topics: Animals; Cells, Cultured; Chlorpromazine; Colloids; Endothelium, Vascular; Hemolysis; Injections, In

2000
Hemolysis of erythrocytes by primary pharmacologic agents, part 2: influence of the vehicle.
    American journal of hospital pharmacy, 1976, Volume: 33, Issue:12

    Topics: Brompheniramine; Chlordiazepoxide; Chlorpromazine; Erythrocytes; Hemolysis; Humans; Hydrogen-Ion Con

1976
[Antihemolytic effect of various benzodiazepines on human erythrocytes].
    Acta biologica et medica Germanica, 1976, Volume: 35, Issue:10

    Topics: Anti-Anxiety Agents; Chlordiazepoxide; Chlorpromazine; Erythrocytes; Hemolysis; Humans; Medazepam; O

1976
Continuous-flow determination of serum inorganic phosphate with a single reagent--the vanadomolybdate method re-evaluated.
    Clinical chemistry, 1977, Volume: 23, Issue:7

    Topics: Acids; Anticoagulants; Bilirubin; Chlorpromazine; Evaluation Studies as Topic; Hemolysis; Humans; Me

1977
Possible role for chlorpromazine in protection against myocardial infarction.
    Lancet (London, England), 1979, Apr-14, Volume: 1, Issue:8120

    Topics: Anticoagulants; Chlorpromazine; Coronary Disease; Hemolysis; Humans; Myocardial Infarction; Platelet

1979
Chlorpromazine in prophylaxis of myocardial infarction.
    Lancet (London, England), 1979, Jun-30, Volume: 1, Issue:8131

    Topics: Chlorpromazine; Hemolysis; Humans; Myocardial Infarction

1979
The action of chelating agents and local anesthetics on the terminal stages of immune hemolysis.
    Molecular immunology, 1979, Volume: 16, Issue:11

    Topics: 2,2'-Dipyridyl; Anesthetics, Local; Animals; Chelating Agents; Chlorpromazine; Complement System Pro

1979
Ca2+ regulated modulator protein interacting agents: inhibition of Ca2+-Mg2+-ATPase of human erythrocyte ghost.
    Biochemical and biophysical research communications, 1979, Jun-13, Volume: 88, Issue:3

    Topics: Amitriptyline; Brain; Calcium-Transporting ATPases; Calmodulin; Carrier Proteins; Chlorpromazine; Er

1979
Chlorpromazine and protriptyline phototoxicity: photosensitized, oxygen independent red cell hemolysis.
    Photochemistry and photobiology, 1979, Volume: 29, Issue:4

    Topics: Chlorpromazine; Dibenzocycloheptenes; Erythrocyte Membrane; Hemolysis; Humans; Light; Protriptyline

1979
Use of enzymatic and electron microscopy (freeze-etching) methods for studying ATP-dependent masking of erythrocyte membrane phospholipids.
    Israel journal of medical sciences, 1979, Volume: 15, Issue:8

    Topics: Adenosine Triphosphate; Animals; Anura; Chickens; Chlorpromazine; Erythrocyte Membrane; Erythrocytes

1979
Inhibition of platelet thrombus formation by chlorpromazine acting to diminish haemolysis.
    Nature, 1979, Nov-08, Volume: 282, Issue:5735

    Topics: Adenosine Diphosphate; Blood Coagulation; Chlorpromazine; Depression, Chemical; Dose-Response Relati

1979
Photobiochemistry in the dark: photohemolysis of red cells sensitized by chlorpromazine-bioenergized triplet acetone system.
    Biochemical and biophysical research communications, 1979, Nov-28, Volume: 91, Issue:2

    Topics: Acetone; Aldehydes; Chlorpromazine; Darkness; Erythrocytes; Hemolysis; Humans; Kinetics; Oxygen Cons

1979
Experiments to illustrate the effect of chlorpromazine on the permeability of the bacterial cell wall.
    Acta pathologica et microbiologica Scandinavica. Section B, Microbiology, 1979, Volume: 87, Issue:5

    Topics: Bacteria; Cell Membrane Permeability; Cell Wall; Chlorpromazine; Hemolysis; Staphylococcus aureus

1979
The asymmetric distribution of chlorpromazine and its quaternary analogue over the erythrocyte membrane.
    Biochemical pharmacology, 1977, Dec-15, Volume: 26, Issue:24

    Topics: Chlorpromazine; Erythrocyte Membrane; Erythrocytes; Hemolysis; Humans; In Vitro Techniques; Kinetics

1977
The role of erythrocytes in initial haemostatic plug formation.
    Bibliotheca anatomica, 1977, Issue:16 Pt 2

    Topics: Adenosine; Animals; Arterioles; Blood Platelets; Chlorpromazine; Erythrocytes; Extracorporeal Circul

1977
Effect of drugs on human erythrocytes--4. Protecting effect of dextran on drug-induced hemolysis.
    Biochemical pharmacology, 1978, Volume: 27, Issue:8

    Topics: Chlorpromazine; Clemastine; Dextrans; Diffusion; Erythrocytes; Hemoglobins; Hemolysis; Humans; In Vi

1978
Primary mechanisms of erythrocyte photolysis induced by biological sensitizers and phototoxic drugs.
    Photochemistry and photobiology, 1975, Volume: 22, Issue:5

    Topics: Chlorpromazine; Demeclocycline; Erythrocytes; Hematoporphyrins; Hemolysis; Kynurenic Acid; Photolysi

1975
Biological membranes as bilayer couples. III. Compensatory shape changes induced in membranes.
    The Journal of cell biology, 1976, Volume: 70, Issue:1

    Topics: Adenosine Triphosphate; Animals; Antigen-Antibody Reactions; Azides; Cell Membrane; Chlorpromazine;

1976
Effects of different doses of chlorpromazine on renal function in the dog.
    Scandinavian journal of clinical and laboratory investigation, 1976, Volume: 36, Issue:8

    Topics: Animals; Blood Pressure; Chlorpromazine; Dogs; Female; Glomerular Filtration Rate; Hemoglobins; Hemo

1976
Stoichiometry of compounds bound to human erythrocytes in relation to morphology.
    The Journal of biological chemistry, 1975, Apr-25, Volume: 250, Issue:8

    Topics: Binding Sites; Chlorpromazine; Erythrocytes; Hemolysis; Humans; Kinetics; Mathematics; Methylene Blu

1975
Effects of chlorpromazine on bilirubin metabolism and biliary secretion in the rat.
    Gastroenterology, 1975, Volume: 69, Issue:4

    Topics: Animals; Bile; Bilirubin; Chlorpromazine; Cholestasis; Heme; Hemolysis; Liver; Male; Rats

1975
Use of microphotohemolysis to distinguish differences in erythrocyte treatments.
    Blood cells, 1991, Volume: 17, Issue:3

    Topics: Animals; Chlorpromazine; Dextrans; Diamide; Dose-Response Relationship, Radiation; Erythrocytes; Flu

1991
[The effect of chlorpromazine on the temperature and osmotic sensitivity of erythrocytes].
    Biokhimiia (Moscow, Russia), 1991, Volume: 56, Issue:12

    Topics: Chlorpromazine; Cold Temperature; Erythrocytes; Hemolysis; Humans; Osmosis

1991
Species differences in response to photohemolytic agents.
    Photochemistry and photobiology, 1991, Volume: 53, Issue:4

    Topics: Animals; Chlorpromazine; Dogs; Erythrocytes; Free Radical Scavengers; Hemolysis; Humans; In Vitro Te

1991
Stabilizing effects of some amino acids on membranes of rabbit erythrocytes perturbed by chlorpromazine.
    Journal of pharmaceutical sciences, 1989, Volume: 78, Issue:1

    Topics: Amino Acids; Animals; Aspartic Acid; Chlorpromazine; Erythrocyte Membrane; Glycine; Half-Life; Hemol

1989
Effects of purines and forskolin on haemolysis.
    Fundamental & clinical pharmacology, 1987, Volume: 1, Issue:3

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Anesthetics, Loca

1987
Influence of chlorpromazine on the transverse mobility of phospholipids in the human erythrocyte membrane: relation to shape changes.
    Biochimica et biophysica acta, 1988, Jul-21, Volume: 942, Issue:2

    Topics: Chlorpromazine; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Erythrocytes; Hemolysis;

1988
Influence of dietary lipids on the effect of chlorpromazine on membrane properties of rabbit red cells.
    Proceedings of the Royal Society of London. Series B, Biological sciences, 1986, Feb-22, Volume: 227, Issue:1246

    Topics: Animals; Chlorpromazine; Dietary Fats; Erythrocyte Deformability; Erythrocyte Membrane; Hemolysis; I

1986
Entrapping of the spin label tempocholine into human erythrocytes by resealing after hyposmolar stress. Comparison with haemolysis. The effects of some membrane-active substances.
    Biochemical pharmacology, 1985, Jan-01, Volume: 34, Issue:1

    Topics: Calcium; Calmodulin; Chlorpromazine; Cyclic N-Oxides; Edetic Acid; Electron Spin Resonance Spectrosc

1985
Trifluoperazine inhibits Sendai virus-induced hemolysis.
    Biochimica et biophysica acta, 1986, Apr-14, Volume: 856, Issue:2

    Topics: Animals; Chick Embryo; Chlorpromazine; Erythrocyte Membrane; Erythrocytes; Hemolysis; Humans; Kineti

1986
Differential effects of chlorpromazine on secretion, protein phosphorylation and phosphoinositide metabolism in stimulated platelets.
    The Biochemical journal, 1986, Aug-15, Volume: 238, Issue:1

    Topics: Blood Platelets; Blood Proteins; Chlorpromazine; Dose-Response Relationship, Drug; Hemolysis; Humans

1986
Application of differential flow microcalorimetry for study of drug interactions in the blood system.
    Journal of biochemical and biophysical methods, 1988, Volume: 16, Issue:4

    Topics: Blood Proteins; Calorimetry, Differential Scanning; Chlorpromazine; Erythrocyte Membrane; Erythrocyt

1988
Stimulation by trifluoperazine of p-aminohippurate accumulation in rat kidney cortical slices.
    Archives internationales de pharmacodynamie et de therapie, 1987, Volume: 288, Issue:2

    Topics: Adenosine Triphosphate; Aminohippuric Acids; Animals; Chlorpromazine; Dibucaine; Hemolysis; In Vitro

1987
Tests for local toxicity of intramuscular drug preparations: comparison of in vivo and in vitro methods.
    Acta pharmacologica et toxicologica, 1985, Volume: 56, Issue:2

    Topics: Animals; Chlorpromazine; Clopenthixol; Creatine Kinase; Digoxin; Female; Hemolysis; In Vitro Techniq

1985
The effect of nervous active drugs on MG ++ -dependent ATPase in erythrocyte membrane.
    Archives internationales de physiologie et de biochimie, 1971, Volume: 79, Issue:5

    Topics: Adenosine Triphosphatases; Atropine; Cell Membrane; Chlorpromazine; Enzyme Activation; Ephedrine; Er

1971
Effect of beta-carotene on photohemolysis.
    Acta dermato-venereologica, 1973, Volume: 53, Issue:4

    Topics: Adult; Carotenoids; Chlorpromazine; Demeclocycline; Erythrocytes; Hemolysis; Humans; In Vitro Techni

1973
Temperature-dependent reaction of flufenamic acid with rat erythrocyte membrane.
    Biochemical pharmacology, 1973, Apr-15, Volume: 22, Issue:8

    Topics: Anesthetics, Local; Animals; Anti-Inflammatory Agents; Cell Membrane; Chlorpromazine; Dose-Response

1973
Interactions of membrane stabilizing drugs affecting human erythrocytes in vitro.
    European journal of pharmacology, 1973, Volume: 22, Issue:1

    Topics: Acetanilides; Adrenergic beta-Antagonists; Amino Alcohols; Chlorpromazine; Diazepam; Dose-Response R

1973
[Studies on the lysolecithin-metabolizing enzymes of intact erythrocytes and modified stromas].
    Folia haematologica (Leipzig, Germany : 1928), 1968, Volume: 90, Issue:2

    Topics: Acyltransferases; Adenosine Triphosphate; Amitriptyline; Antibodies; Cell Membrane; Chlorpromazine;

1968
The structure-activity relationship of tricyclic amines.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 177, Issue:1

    Topics: Adenosine Triphosphatases; Amines; Chemical Phenomena; Chemistry; Chloroform; Chlorpromazine; Erythr

1971
Detection of chlorpromazine and thioridazine metabolites in human erythrocytes.
    Journal of chromatography, 1969, Nov-11, Volume: 44, Issue:3

    Topics: Chlorpromazine; Chromatography, Thin Layer; Erythrocytes; Hemolysis; Humans; Indicators and Reagents

1969
Drug allergy. II.
    British medical journal, 1971, Apr-10, Volume: 2, Issue:5753

    Topics: Aged; Anemia, Hemolytic; Antigen-Antibody Reactions; Blood Platelets; Chlorpromazine; Dermatitis, Co

1971
Hemolysis of erythrocytes by primary pharmacologic agents.
    American journal of hospital pharmacy, 1971, Volume: 28, Issue:12

    Topics: Animals; Brompheniramine; Chlordiazepoxide; Chlorpromazine; Diphenhydramine; Doxapram; Erythrocytes;

1971
Cellular mechanisms of chlorpromazine photosensitivity.
    Proceedings of the Royal Society of Medicine, 1974, Volume: 67, Issue:9

    Topics: Cell Membrane; Cell Survival; Cells, Cultured; Chlorpromazine; Erythrocytes; Hemolysis; Humans; Ligh

1974
Biological membranes as bilayer couples. A molecular mechanism of drug-erythrocyte interactions.
    Proceedings of the National Academy of Sciences of the United States of America, 1974, Volume: 71, Issue:11

    Topics: Binding Sites; Cell Membrane; Cell Membrane Permeability; Chlorpromazine; Erythrocytes; Hemolysis; H

1974
The hemolytic effect of some phenothiazine derivatives in vitro and in vivo.
    Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 196, Issue:1

    Topics: Animals; Cell Membrane Permeability; Chlorpromazine; Dogs; Erythrocytes; Glucose; Hemoglobins; Hemol

1972
New approaches to investigating UVL photo protective substances in vitro.
    Archiv fur dermatologische Forschung, 1973, Volume: 248, Issue:3

    Topics: 1-Propanol; Aminobenzoates; Aniline Compounds; beta-Aminoethyl Isothiourea; Candida albicans; Chlorp

1973
[Two devices for perfusion of isolated rat brain].
    Arzneimittel-Forschung, 1972, Volume: 22, Issue:7

    Topics: Absorption; Animals; Brain; Chlorpromazine; Electroencephalography; Filtration; Hemolysis; Male; Met

1972
Inhibition of hemolysis by tricyclic dyestuffs--fluorescein-phenothiazine antagonism.
    Biochemical pharmacology, 1973, Jun-15, Volume: 22, Issue:12

    Topics: Anemia, Hemolytic; Chlorpromazine; Coloring Agents; Erythrocytes; Fluoresceins; Hemolysis; Humans; I

1973
[Physiopathological aspects of immunohemolysis and its inhibition].
    Die Medizinische Welt, 1973, Apr-13, Volume: 24, Issue:15

    Topics: Antigen-Antibody Reactions; Binding Sites, Antibody; Cell Membrane; Chlorpromazine; Cold Temperature

1973
Binding of phenothiazines to proteins--measurement of binding based on the inhibition of the hemolytic activity of phenothiazines on sheep red blood cells.
    Biochemical pharmacology, 1973, Oct-01, Volume: 22, Issue:19

    Topics: Animals; Blood Proteins; Cattle; Chickens; Chlorpromazine; Dogs; Erythrocytes; Hemolysis; Humans; Hy

1973
Ultraviolet light protection by several new compounds.
    Archives of dermatology, 1974, Volume: 109, Issue:4

    Topics: Administration, Topical; Aminobenzoates; Anthracenes; Antioxidants; beta-Aminoethyl Isothiourea; Bro

1974
Acetylcholine esterase as a probe for erythrocyte-membrane intactness.
    Biochimica et biophysica acta, 1974, Mar-29, Volume: 339, Issue:3

    Topics: Acetylcholinesterase; Cell Membrane; Chlorpromazine; Erythrocytes; Evaluation Studies as Topic; Hemo

1974
Effect of phenothiazine drugs on the stability of rat liver subcellular particles.
    Advances in biochemical psychopharmacology, 1974, Volume: 9, Issue:0

    Topics: Acclimatization; Acid Phosphatase; Adenosine Triphosphate; Animals; Body Temperature; Chlorpromazine

1974
A new prolonged-acting type of chlorpromazine: behavioral effects and prolonged actions on nerve membranes.
    Canadian journal of physiology and pharmacology, 1974, Volume: 52, Issue:3

    Topics: Amphetamine; Animals; Anura; Behavior, Animal; Biopharmaceutics; Carbon Radioisotopes; Cell Membrane

1974
Membrane expansion of erythrocyte ghosts by tranquilizers and anesthetics.
    Biochimica et biophysica acta, 1969, Volume: 183, Issue:3

    Topics: Alcohols; Cell Membrane; Chlorpromazine; Erythrocytes; Hematocrit; Hemolysis; Humans; In Vitro Techn

1969
The haemolytic effect of some phenothiazine derivatives.
    Annales medicinae experimentalis et biologiae Fenniae, 1965, Volume: 43, Issue:2

    Topics: Animals; Anticoagulants; Blood Platelets; Cell Membrane Permeability; Chlorpromazine; Citrates; Colo

1965
Anesthetics expand erythrocyte membranes without causing loss of K + .
    Biochimica et biophysica acta, 1972, Jan-17, Volume: 255, Issue:1

    Topics: Alcohols; Anesthetics, Local; Biological Transport; Cell Membrane; Chlorpromazine; Erythrocytes; Fat

1972
The membrane concentrations of neutral and positive anesthetics (alcohols, chlorpromazine, morphine) fit the Meyer-Overton rule of anesthesia; negative narcotics do not.
    Biochimica et biophysica acta, 1972, Jan-17, Volume: 255, Issue:1

    Topics: Alcohols; Anesthetics; Animals; Barbiturates; Carbon Isotopes; Cell Membrane; Chlorpromazine; Erythr

1972
[Topical effect of sedatives and prednisolone succinate on osmotic and immune hemolysis].
    Blut, 1972, Volume: 25, Issue:3

    Topics: Cell Membrane; Chlorpromazine; Erythrocytes; Haloperidol; Hemagglutination Inhibition Tests; Hemolys

1972
Effect of drugs on the hemolysis of rat erythrocytes.
    Biochemical pharmacology, 1969, Volume: 18, Issue:9

    Topics: Animals; Aspirin; Bile Acids and Salts; Chlordiazepoxide; Chloroquine; Chlorpromazine; Chlorprothixe

1969
Effect of drugs on red cell fragility.
    Nature, 1970, Mar-21, Volume: 225, Issue:5238

    Topics: Acetylcholine; Amobarbital; Amphetamine; Atropine; Barbiturates; Bemegride; Cell Membrane; Chlorprom

1970
The influence of ATP Riboflavin, Succinate, and Glutamate in vitro on the haemolytic action of Chlorpromazine.
    Comptes rendus de l'Academie Bulgare des sciences : sciences mathematiques et naturelles, 1970, Volume: 23, Issue:2

    Topics: Adenosine Triphosphate; Animals; Cattle; Chlorpromazine; Erythrocytes; Glutamates; Hemolysis; Method

1970
Membrane stabilization and cardiac effects of d,1-propranolol, d-propranolol and chlorpromazine.
    European journal of pharmacology, 1970, Volume: 13, Issue:1

    Topics: Animals; Cell Membrane; Chlorpromazine; Coronary Vessels; Depression, Chemical; Erythrocytes; Female

1970
The effects of phenothiazines on human erythrocytes: an ultrastructural study.
    British journal of haematology, 1971, Volume: 20, Issue:5

    Topics: Cell Membrane; Chlorpromazine; Erythrocytes; Hemolysis; Humans; In Vitro Techniques; Microscopy, Ele

1971
Effect of phenothiazine on the red cells of paroxysmal nocturnal haemoglobinuria.
    British journal of haematology, 1968, Volume: 14, Issue:4

    Topics: Animals; Blood Transfusion; Cell Membrane; Chlorpromazine; Chromium Isotopes; Erythrocytes; Hemoglob

1968
The effects of beta-diethylaminoethyl-diphenylpropylacetate (SKE 525-A) on biological membranes. I. SKF 525-A-induced stabilization of human erythrocytes.
    Biochemical pharmacology, 1968, Volume: 17, Issue:8

    Topics: Cell Membrane; Chlorpromazine; Erythrocytes; Hemolysis; Humans; Hydrogen-Ion Concentration; Osmolar

1968
The influence of chlorpromazine on human erythrocytes.
    Biochemical pharmacology, 1968, Volume: 17, Issue:10

    Topics: Blood Sedimentation; Cell Membrane; Chlorpromazine; Erythrocytes; Hematocrit; Hemolysis; Humans; Iso

1968
Membrane expansion of intact erythrocytes by anesthetics.
    Biochimica et biophysica acta, 1969, Volume: 183, Issue:3

    Topics: Alcohols; Anesthetics; Cell Membrane; Chlorpromazine; Erythrocytes; Hematocrit; Hemolysis; Humans; I

1969
Membrane expansion of the erythrocyte by both the neutral and ionized forms of chlorpromazine.
    Biochimica et biophysica acta, 1969, Volume: 183, Issue:3

    Topics: Cell Membrane; Chlorpromazine; Erythrocytes; Hemolysis; Humans; Hydrogen-Ion Concentration; In Vitro

1969
[Hemolytic stability of erythrocytes in schizophrenia].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1965, Volume: 65, Issue:8

    Topics: Chlorpromazine; Erythrocytes; Hemolysis; Humans; Schizophrenia

1965
5-Hydroxytryptamine release from blood platelets and haemolysis of red blood cells of rabbit induced by phenothiazines and related compounds.
    Annales medicinae experimentalis et biologiae Fenniae, 1966, Volume: 44, Issue:3

    Topics: Animals; Blood Platelets; Chlorpromazine; Erythrocytes; Hemolysis; Male; Phenothiazines; Rabbits; Re

1966