chlorpromazine has been researched along with Hemolysis in 114 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Hemolysis: The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Influence of divalent Ca2+ ions in sulphonated chlorophthalocyanine (ClAlPcS2) induced photohemolysis in rabbit red blood cells has been investigated." | 7.70 | Effects of calcium on phthalocyanine sensitized photohemolysis. ( Jain, V; Varshney, R, 1998) |
| "Sendai virus-induced hemolysis, a manifestation of virus-red cell fusion, is inhibited by exposure of the virus to 50 microM and higher concentrations of trifluoperazine." | 7.67 | Trifluoperazine inhibits Sendai virus-induced hemolysis. ( MacDonald, RI, 1986) |
| "Influence of divalent Ca2+ ions in sulphonated chlorophthalocyanine (ClAlPcS2) induced photohemolysis in rabbit red blood cells has been investigated." | 3.70 | Effects of calcium on phthalocyanine sensitized photohemolysis. ( Jain, V; Varshney, R, 1998) |
| "Since amphiphilic drugs are known to interact with biomembranes, we investigated local vessel damage and thrombosis which might be brought about by intravenous dosing using chlorpromazine (CPZ) as a representative compound." | 3.70 | Local thrombus formation in the site of intravenous injection of chlorpromazine: possible colloid-osmotic lysis of the local endothelial cells. ( Kanamaru, H; Kaneko, H; Nishibe, H; Tani, N; Yabuki, M; Yoshioka, T, 2000) |
| " The kinetic studies in isotonic suspensions of erythrocytes indicated that the hemolysis induced by the amphipathic drug chlorpromazine (CPZ) or flufenamic acid (FA) was retarded by addition of sugars, and the degree of the anti-hemolytic effect increased with increases in molecular size." | 3.69 | Protective effects of neutral amino acids against amphipathic drug-induced hemolysis. ( Iida, T; Kado, Y; Morimoto, Y; Shiota, M; Takeuchi, Y; Yutani, Y, 1995) |
| "By a photohemolysis test we assessed in vitro the phototoxic properties of 12 phenothiazines (chlorpromazine, dixyrazine, fluphenazine, levomepromazine, perazine, perphenazine, promazine, promethazine, prothipendyl, thioridazine, trifluoperazine, triflupromazine) and 5 thioxanthenes (chlorprothixene, clopenthixol, flupenthixol, thiothixene, zuclopenthixol)." | 3.69 | Phototoxic properties of neuroleptic drugs. ( Bindl, A; Eberlein-König, B; Przybilla, B, 1997) |
| " In the present study, we determined that, in fact, cyclodextrin polysulfate (CDS) actively protected erythrocytes against hemolysis induced by a wide spectrum of hemolytically active substances, ranging from pharmaceuticals, such as chlorpromazine, to solid suspensions of siliceous particles." | 3.68 | Protection of erythrocytes against hemolytic agents by cyclodextrin polysulfate. ( Kumor, K; Macarak, EJ; Weisz, PB, 1993) |
| "Hemolysis experiments indicated that glycine (20 mM) remarkably suppressed the chlorpromazine (CPZ)-induced osmotic permeability enhancing effect in rabbit erythrocytes." | 3.67 | Stabilizing effects of some amino acids on membranes of rabbit erythrocytes perturbed by chlorpromazine. ( Fukuda, T; Fukumori, Y; Kaneko, I; Morimoto, Y; Takeuchi, Y; Yamaoka, Y, 1989) |
| "Sendai virus-induced hemolysis, a manifestation of virus-red cell fusion, is inhibited by exposure of the virus to 50 microM and higher concentrations of trifluoperazine." | 3.67 | Trifluoperazine inhibits Sendai virus-induced hemolysis. ( MacDonald, RI, 1986) |
| " The heat produced in erythrocyte hemolysis induced by chlorpromazine hydrochloride (CPZ) and the binding heat of CPZ to human blood components viz." | 3.67 | Application of differential flow microcalorimetry for study of drug interactions in the blood system. ( Aki, H; Yamamoto, M, 1988) |
| "beta-Cyclodextrin (beta-CyD) significantly protected the human erythrocytes from hemolysis and shape changes induced with chlorpromazine and flufenamic acid in isotonic solution." | 3.66 | Protective effects of cyclodextrins on drug-induced hemolysis in vitro. ( Irie, T; Otagiri, M; Sunada, M; Tsubaki, K; Uekama, K, 1981) |
| "The hemolysis of human red cells in the presence of chlorpromazine and 2-methylpropanal, or propanal, has been studied by a spectrophotometric method." | 3.66 | Synergistic effect of chlorpromazine and alkanals on the human red blood cells. ( Durán, N; Haun, M; Makita, Y; Vercesi, AE, 1981) |
| " Acute CPZ treatment (25 mg per kg intravenously) produced hemolysis and resulted in increased bilirubin output and stimulation of hepatic heme synthesis." | 3.65 | Effects of chlorpromazine on bilirubin metabolism and biliary secretion in the rat. ( Knodell, RG, 1975) |
| "Photohemolysis is an accurate tool for demonstrating DMCT phototoxicity." | 1.27 | Studies on photohemolysis with special reference to demethylchlortetracycline. ( Bjellerup, M; Ljunggren, B, 1984) |
| "The chlorpromazine-induced lysis was markedly enhanced by thrombin and phorbol ester, and complete cytolysis was found at chlorpromazine concentrations of 100 microM and above in the presence of thrombin." | 1.27 | Differential effects of chlorpromazine on secretion, protein phosphorylation and phosphoinositide metabolism in stimulated platelets. ( Aarsaether, N; Holmsen, H; Lillehaug, JR; Opstvedt, A; Rongved, S, 1986) |
| " The results of this study suggest that the in vitro tests employed can be useful as screening tests for local toxic effect of intramuscular drug preparations." | 1.27 | Tests for local toxicity of intramuscular drug preparations: comparison of in vivo and in vitro methods. ( Bagdon, RE; Højelse, F; Svendsen, O, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 97 (85.09) | 18.7374 |
| 1990's | 13 (11.40) | 18.2507 |
| 2000's | 3 (2.63) | 29.6817 |
| 2010's | 1 (0.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Favretto, ME | 1 |
| Cluitmans, JC | 1 |
| Bosman, GJ | 1 |
| Brock, R | 1 |
| LINDBERG, LG | 1 |
| NORDEN, A | 1 |
| HARRISON, GA | 1 |
| ROSEN, M | 1 |
| GOODALL, P | 1 |
| KATZ, R | 1 |
| VELASCO, M | 1 |
| GUZMAN, C | 1 |
| ALESSANDRI, H | 1 |
| Abajo, C | 1 |
| Boffill, MA | 1 |
| del Campo, J | 1 |
| Alexandra Méndez, M | 1 |
| González, Y | 1 |
| Mitjans, M | 1 |
| Pilar Vinardell, M | 1 |
| Mao, TS | 2 |
| Noval, JJ | 2 |
| Becker, GA | 1 |
| Pisciotta, AV | 1 |
| van Steveninck, J | 2 |
| Gjösũnd, WK | 1 |
| Booij, HL | 1 |
| Saunders, DM | 1 |
| Minetti, M | 1 |
| Ceccarini, M | 1 |
| Di Stasi, AM | 1 |
| Born, GV | 8 |
| Görög, P | 1 |
| Kratzer, MA | 1 |
| Uekama, K | 3 |
| Irie, T | 3 |
| Sunada, M | 2 |
| Otagiri, M | 2 |
| Iwasaki, K | 1 |
| Okano, Y | 1 |
| Miyata, T | 1 |
| Kasé, Y | 1 |
| Panijpan, B | 1 |
| Kantakanit, N | 1 |
| Housley, GM | 2 |
| Baba, Y | 1 |
| Nakao, Y | 1 |
| Kishihara, M | 1 |
| Kobayashi, N | 1 |
| Kimoto, H | 1 |
| Matsukura, S | 1 |
| Fujita, T | 1 |
| Kuma, K | 1 |
| Bjellerup, M | 2 |
| Ljunggren, B | 2 |
| Janoff, AS | 1 |
| Mazorow, DL | 1 |
| Coughlin, RT | 1 |
| Bowdler, AJ | 1 |
| Haug, A | 1 |
| McGroarty, EJ | 1 |
| Mishra, KP | 2 |
| Binh, LD | 1 |
| Singh, BB | 2 |
| Möller, H | 1 |
| Beresford, RA | 1 |
| Fastier, FN | 1 |
| Rao, MN | 1 |
| Bhise, SB | 1 |
| Srivastava, RC | 1 |
| Lieber, MR | 2 |
| Lange, Y | 1 |
| Weinstein, RS | 1 |
| Steck, TL | 2 |
| Kochevar, IE | 2 |
| Hom, J | 1 |
| Smith, JE | 1 |
| Mohandas, N | 1 |
| Clark, MR | 1 |
| Greenquist, AC | 1 |
| Shohet, SB | 1 |
| Wehmeier, A | 2 |
| Tsubaki, K | 1 |
| Srinivasan, VT | 1 |
| Makita, Y | 2 |
| Vercesi, AE | 1 |
| Haun, M | 1 |
| Durán, N | 2 |
| Shiotani, K | 1 |
| Uehata, K | 1 |
| Hirayama, F | 1 |
| Thompson, AA | 1 |
| Cornelius, AS | 1 |
| Asakura, T | 1 |
| Horiuchi, K | 1 |
| Yamaguchi, T | 1 |
| Matsumoto, M | 1 |
| Kimoto, E | 1 |
| Weisz, PB | 1 |
| Kumor, K | 1 |
| Macarak, EJ | 1 |
| Shpakova, NM | 2 |
| Pantaler, ER | 1 |
| Bondarenko, VA | 2 |
| Babu, AS | 1 |
| Gowda, TV | 1 |
| Morimoto, Y | 2 |
| Yutani, Y | 1 |
| Kado, Y | 1 |
| Iida, T | 1 |
| Shiota, M | 1 |
| Takeuchi, Y | 2 |
| Rudenko, SV | 1 |
| Nipot, EE | 1 |
| Eberlein-König, B | 1 |
| Bindl, A | 1 |
| Przybilla, B | 1 |
| Varshney, R | 1 |
| Jain, V | 1 |
| Hägerstrand, H | 1 |
| Danieluk, M | 1 |
| Bobrowska-Hägerstrand, M | 1 |
| Iglic, A | 1 |
| Wróbel, A | 1 |
| Isomaa, B | 1 |
| Nikinmaa, M | 1 |
| Yabuki, M | 1 |
| Tani, N | 1 |
| Yoshioka, T | 1 |
| Nishibe, H | 1 |
| Kanamaru, H | 1 |
| Kaneko, H | 1 |
| Ansel, HC | 2 |
| Gigandet, MP | 2 |
| Terhaag, B | 1 |
| Bockisch, A | 1 |
| Baadenhuijsen, H | 1 |
| Seuren-Jacobs, HE | 1 |
| Jansen, AP | 1 |
| Esser, AF | 1 |
| Kobayashi, R | 1 |
| Tawata, M | 1 |
| Hidaka, H | 1 |
| Schubothe, H | 1 |
| Maas, D | 1 |
| Weber, S | 1 |
| Lamola, AA | 1 |
| Loyter, A | 1 |
| Gazitt, Y | 1 |
| Ohad, I | 1 |
| Kristiansen, JE | 1 |
| Elfernik, JG | 1 |
| Bergqvist, D | 1 |
| Arfors, KE | 1 |
| Ogiso, T | 1 |
| Masuda, H | 1 |
| Oue, S | 1 |
| Nilsson, R | 1 |
| Swanbeck, G | 2 |
| Wennersten, G | 2 |
| Sheetz, MP | 2 |
| Painter, RG | 1 |
| Singer, SJ | 2 |
| Berg, KJ | 1 |
| Bergan, A | 1 |
| Lovrien, R | 1 |
| Tisel, W | 1 |
| Pesheck, P | 1 |
| Knodell, RG | 1 |
| Miller, FN | 1 |
| Tangelder, GJ | 1 |
| Slaaf, DW | 1 |
| Reneman, RS | 1 |
| Robertson, DG | 1 |
| Bailey, DL | 1 |
| Martin, RA | 1 |
| Yamaoka, Y | 1 |
| Kaneko, I | 1 |
| Fukumori, Y | 1 |
| Fukuda, T | 1 |
| Gonçalves, ML | 1 |
| Ribeiro, JA | 1 |
| Rosso, J | 1 |
| Zachowski, A | 1 |
| Devaux, PF | 1 |
| Housley, G | 1 |
| Conroy, DM | 1 |
| Belin, J | 1 |
| Smith, AD | 1 |
| Lagercrantz, C | 1 |
| Larsson, T | 1 |
| Tollsten, L | 1 |
| Prus, K | 1 |
| MacDonald, RI | 1 |
| Opstvedt, A | 1 |
| Rongved, S | 1 |
| Aarsaether, N | 1 |
| Lillehaug, JR | 1 |
| Holmsen, H | 1 |
| Yamamoto, M | 1 |
| Aki, H | 1 |
| Gemba, M | 1 |
| Ushijima, H | 1 |
| Nakajima, M | 1 |
| Nakano, S | 1 |
| Svendsen, O | 1 |
| Højelse, F | 1 |
| Bagdon, RE | 1 |
| Mircevová, L | 1 |
| Simonová, A | 1 |
| Tanaka, K | 1 |
| Kobayashi, K | 1 |
| Kazui, S | 1 |
| Olaisen, B | 1 |
| Oye, I | 1 |
| Ferber, E | 1 |
| Munder, PG | 1 |
| Kohlschütter, A | 1 |
| Fischer, H | 1 |
| Baur, EW | 2 |
| Zingales, IA | 1 |
| Fievet, CJ | 1 |
| Johnson, BE | 1 |
| Santos-Martinez, J | 1 |
| Aviles, TA | 1 |
| Laboy-Torres, JA | 1 |
| Kahn, G | 2 |
| Curry, MC | 2 |
| Dustin, R | 1 |
| Fleck, W | 1 |
| Krieglstein, J | 1 |
| Urban, W | 1 |
| Bube, FW | 1 |
| Aloni, B | 1 |
| Livne, A | 1 |
| Popov, CS | 2 |
| Seeman, P | 6 |
| Machleidt, H | 1 |
| Kähling, J | 1 |
| Sengupta, S | 1 |
| Kwant, WO | 4 |
| Sauks, T | 2 |
| Ahtee, L | 2 |
| Paasonen, MK | 1 |
| Roth, S | 2 |
| Bube, F | 1 |
| Sehrbundt, M | 1 |
| Sheppard, H | 1 |
| Tsien, WH | 1 |
| Burghardt, C | 1 |
| Mikikits, W | 1 |
| Mortara, A | 1 |
| Spector, RG | 1 |
| Yordanov, IM | 1 |
| Nikiforova, MN | 1 |
| Langslet, A | 1 |
| Preston, FE | 1 |
| Lee, D | 1 |
| Laforet, MT | 1 |
| Gardner, FH | 1 |
| Lee, IP | 1 |
| Yamamura, HI | 1 |
| Dixon, RL | 1 |
| Argent, W | 1 |
| Lideman, RR | 1 |
| Ir'ianov, IuI | 1 |
1 review available for chlorpromazine and Hemolysis
| Article | Year |
|---|---|
[Drug induced immune hemolytic anemia].
Topics: Anemia, Hemolytic; Anemia, Hemolytic, Autoimmune; Antibody Formation; Antigen-Antibody Complex; Auto | 1978 |
113 other studies available for chlorpromazine and Hemolysis
| Article | Year |
|---|---|
Human erythrocytes as drug carriers: loading efficiency and side effects of hypotonic dialysis, chlorpromazine treatment and fusion with liposomes.
Topics: Antipsychotic Agents; beta-Galactosidase; Chlorpromazine; Dialysis; Drug Carriers; Erythrocytes; Flu | 2013 |
Severe hemolytic reaction to chlorpromazine.
Topics: Anemia, Hemolytic; Chlorpromazine; Hemolysis; Humans; Jaundice | 1961 |
HAEMORRHAGIC COMPLICATIONS DURING THE TREATMENT OF TETANUS.
Topics: Amobarbital; Child; Chloramphenicol; Chlorpromazine; Diphenhydramine; Hematuria; Hemolysis; Hydrocor | 1964 |
RED CELL SURVIVAL ESTIMATED BY RADIOACTIVE CHROMIUM IN HEPATOBILIARY DISEASE.
Topics: Alcoholism; Bilirubin; Blood Chemical Analysis; Cell Survival; Chlorpromazine; Chromium; Chromium Is | 1964 |
In vitro study of the antioxidant and immunomodulatory activity of aqueous infusion of Bidens pilosa.
Topics: Adjuvants, Immunologic; Amidines; Antioxidants; Bidens; Chlorpromazine; Hemolysis; Humans; Leukocyte | 2004 |
Some relationships concerning the chemical structure, hemolytic activity, and therapeutic potency of phenothiazines.
Topics: Animals; Cell Membrane Permeability; Chemical Phenomena; Chemistry; Chlorpromazine; Erythrocytes; Fl | 1966 |
Potentiation of hemolytic plaque formation by incubation of immunized spleen cells in phenothiazine derivatives.
Topics: Animals; Antibody Formation; Cell Membrane Permeability; Chlorpromazine; Erythrocytes; Hemolysin Pro | 1967 |
The influence of chlorpromazine on the osmotic fragility of erythrocytes.
Topics: Animals; Cattle; Chlorpromazine; Erythrocyte Count; Erythrocytes; Hemolysis; Humans; Osmotic Fragili | 1967 |
Classical eclampsia with acute intravascular haemolysis.
Topics: Adult; Anemia, Hemolytic; Australia; Blood Chemical Analysis; Blood Platelet Disorders; Chlorpromazi | 1967 |
Role of membrane thermotropic properties on hypotonic hemolysis and hypertonic cryohemolysis of human red blood cells.
Topics: Chlorpromazine; Chymotrypsin; Cold Temperature; Electron Spin Resonance Spectroscopy; Erythrocyte Me | 1984 |
Aggregation of platelets in damaged vessels.
Topics: Adenosine Diphosphate; Animals; Arteries; Arteriosclerosis; Blood Platelets; Chlorpromazine; Collage | 1981 |
Effects of cyclodextrins on chlorpromazine-induced haemolysis and central nervous system responses.
Topics: Animals; Central Nervous System; Chlorpromazine; Cyclodextrins; Dextrins; Drug Interactions; Erythro | 1981 |
Chlorpromazine enhances haemolysis induced by haemin.
Topics: Animals; Chlorpromazine; Diet; Erythrocytes; Heme; Hemin; Hemoglobins; Hemolysis; Humans; In Vitro T | 1983 |
Influence of charge and molecular size on membrane stabilization.
Topics: Amines; Chlorpromazine; Erythrocyte Membrane; Hemolysis; Humans; Osmotic Fragility; Structure-Activi | 1983 |
Effect of various drugs on the binding of thyrotrophin to thyroid plasma membranes.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Anesthetics, Local; Anti-Arrhythmia Agents; Aprotini | 1982 |
Studies on photohemolysis with special reference to demethylchlortetracycline.
Topics: Chlorpromazine; Demeclocycline; Dose-Response Relationship, Radiation; Ferricyanides; Hemoglobins; H | 1984 |
The modification of human erythrocyte membrane structure by membrane stabilizers: an electron spin resonance study.
Topics: Chlorpromazine; Diazepam; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Erythrocytes; | 1981 |
Effect of dielectric discharge on drug treated mammalian cells.
Topics: Animals; Chlorpromazine; Electric Stimulation; Erythrocytes; Erythrosine; Fluoresceins; Hemolysis; L | 1981 |
Experimental studies on the mechanism of benoxaprofen photoreactions.
Topics: Animals; Candida albicans; Chlorpromazine; Female; Hemolysis; Humans; In Vitro Techniques; Mice; Pho | 1983 |
Effects of some S-alkylthiouroniums and related compounds on the osmotic fragility and the membrane expansion of human erythrocytes.
Topics: Chlorpromazine; Erythrocyte Membrane; Erythrocytes; Hemolysis; Humans; In Vitro Techniques; Osmotic | 1980 |
Antihemolytic action of surface active drugs.
Topics: Animals; Chlorpromazine; Dextropropoxyphene; Dibucaine; Goats; Hemolysis; Hypotonic Solutions; Phosp | 1984 |
Effects of modification of the membranes of intact erythrocytes on the anti-haemolytic action of chlorpromazine.
Topics: Chlorpromazine; Erythrocyte Membrane; Hemolysis; Humans; Membrane Lipids; Neuraminidase; Sialic Acid | 1983 |
Interaction of chlorpromazine with the human erythrocyte membrane.
Topics: Biological Transport; Chlorpromazine; Erythrocyte Membrane; Freeze Fracturing; Hemolysis; Humans; Ki | 1984 |
Dynamics of the holes in human erythrocyte membrane ghosts.
Topics: Chlorpromazine; Cholesterol; Erythrocyte Membrane; Erythrocytes; Glutaral; Hemolysis; Humans; Kineti | 1982 |
Photoproducts of chlorpromazine which cause red blood cell lysis.
Topics: Chlorpromazine; Erythrocytes; Hemolysis; Humans; Photolysis | 1983 |
Deformability and spectrin properties in three types of elongated red cells.
Topics: Anemia, Sickle Cell; Animals; Camelids, New World; Chlorpromazine; Erythrocytes; Hemolysis; Humans; | 1980 |
Possible approaches to the pharmacological prevention of myocardial ischaemia.
Topics: Arteriosclerosis; Blood Platelets; Blood Vessels; Chlorpromazine; Coronary Disease; Hemolysis; Human | 1980 |
Protective effects of cyclodextrins on drug-induced hemolysis in vitro.
Topics: Chlorpromazine; Cyclodextrins; Dextrins; Erythrocytes; Flufenamic Acid; Hemolysis; Humans; In Vitro | 1981 |
Interaction between chlorpromazine and radiation damage to human erythrocyte membrane.
Topics: Chlorpromazine; Erythrocyte Membrane; Erythrocytes; Gamma Rays; Hemolysis; Humans; Osmotic Fragility | 1981 |
Synergistic effect of chlorpromazine and alkanals on the human red blood cells.
Topics: Acetaldehyde; Aldehydes; Chlorpromazine; Drug Synergism; Energy Transfer; Erythrocytes; Hemolysis; H | 1981 |
Characterization of the inclusion mode of beta-cyclodextrin sulfate and its effect on the chlorpromazine-induced hemolysis of rabbit erythrocytes.
Topics: Animals; beta-Cyclodextrins; Cells, Cultured; Chemistry, Pharmaceutical; Chlorpromazine; Cyclodextri | 1994 |
Comparative studies of phenothiazine derivatives for their effects on swelling of normal and sickle erythrocytes.
Topics: Adult; Anemia, Sickle Cell; Antipsychotic Agents; Antisickling Agents; Calmodulin; Chlorpromazine; E | 1993 |
Hemolytic properties under hydrostatic pressure of neuraminidase- or protease-treated human erythrocytes.
Topics: Chlorpromazine; Cross-Linking Reagents; Diamide; Endopeptidases; Erythrocyte Membrane; Glycopeptides | 1993 |
Protection of erythrocytes against hemolytic agents by cyclodextrin polysulfate.
Topics: Cells, Cultured; Chlorpromazine; Cyclodextrins; Drug Antagonism; Erythrocytes; Hemolysis; Humans; Su | 1993 |
[Antihemolytic effect of chlorpromazine on erythrocytes in hyperosmotic and cold shock].
Topics: Chlorpromazine; Cold Temperature; Hemolysis; Humans; In Vitro Techniques; Osmolar Concentration; Wat | 1995 |
Effects of chlorpromazine on the enzymatic and toxic properties of the most basic phospholipase A2 from Vipera russelli snake venom.
Topics: Animals; Anticoagulants; Chlorpromazine; Edema; Hemolysis; L-Lactate Dehydrogenase; Lethal Dose 50; | 1995 |
Protective effects of neutral amino acids against amphipathic drug-induced hemolysis.
Topics: Amino Acids; Animals; Carbohydrates; Chlorpromazine; Erythrocytes; Flufenamic Acid; Hemolysis; In Vi | 1995 |
Protection by chlorpromazine, albumin and bivalent cations against haemolysis induced by melittin, [Ala-14]melittin and whole bee venom.
Topics: Albumins; Bee Venoms; Calcium; Cations, Divalent; Cell Size; Chlorpromazine; Erythrocyte Membrane; H | 1996 |
Phototoxic properties of neuroleptic drugs.
Topics: Antipsychotic Agents; Chlorpromazine; Chlorprothixene; Clopenthixol; Dermatitis, Phototoxic; Drug Er | 1997 |
Effects of calcium on phthalocyanine sensitized photohemolysis.
Topics: Animals; Calcium; Calcium Channel Blockers; Chlorpromazine; Egtazic Acid; Erythrocytes; Hemolysis; I | 1998 |
Influence of band 3 protein absence and skeletal structures on amphiphile- and Ca(2+)-induced shape alterations in erythrocytes: a study with lamprey (Lampetra fluviatilis), trout (Onchorhynchus mykiss) and human erythrocytes.
Topics: Abietanes; Animals; Anion Exchange Protein 1, Erythrocyte; Calcimycin; Calcium; Carboxylic Acids; Ce | 2000 |
Local thrombus formation in the site of intravenous injection of chlorpromazine: possible colloid-osmotic lysis of the local endothelial cells.
Topics: Animals; Cells, Cultured; Chlorpromazine; Colloids; Endothelium, Vascular; Hemolysis; Injections, In | 2000 |
Hemolysis of erythrocytes by primary pharmacologic agents, part 2: influence of the vehicle.
Topics: Brompheniramine; Chlordiazepoxide; Chlorpromazine; Erythrocytes; Hemolysis; Humans; Hydrogen-Ion Con | 1976 |
[Antihemolytic effect of various benzodiazepines on human erythrocytes].
Topics: Anti-Anxiety Agents; Chlordiazepoxide; Chlorpromazine; Erythrocytes; Hemolysis; Humans; Medazepam; O | 1976 |
Continuous-flow determination of serum inorganic phosphate with a single reagent--the vanadomolybdate method re-evaluated.
Topics: Acids; Anticoagulants; Bilirubin; Chlorpromazine; Evaluation Studies as Topic; Hemolysis; Humans; Me | 1977 |
Possible role for chlorpromazine in protection against myocardial infarction.
Topics: Anticoagulants; Chlorpromazine; Coronary Disease; Hemolysis; Humans; Myocardial Infarction; Platelet | 1979 |
Chlorpromazine in prophylaxis of myocardial infarction.
Topics: Chlorpromazine; Hemolysis; Humans; Myocardial Infarction | 1979 |
The action of chelating agents and local anesthetics on the terminal stages of immune hemolysis.
Topics: 2,2'-Dipyridyl; Anesthetics, Local; Animals; Chelating Agents; Chlorpromazine; Complement System Pro | 1979 |
Ca2+ regulated modulator protein interacting agents: inhibition of Ca2+-Mg2+-ATPase of human erythrocyte ghost.
Topics: Amitriptyline; Brain; Calcium-Transporting ATPases; Calmodulin; Carrier Proteins; Chlorpromazine; Er | 1979 |
Chlorpromazine and protriptyline phototoxicity: photosensitized, oxygen independent red cell hemolysis.
Topics: Chlorpromazine; Dibenzocycloheptenes; Erythrocyte Membrane; Hemolysis; Humans; Light; Protriptyline | 1979 |
Use of enzymatic and electron microscopy (freeze-etching) methods for studying ATP-dependent masking of erythrocyte membrane phospholipids.
Topics: Adenosine Triphosphate; Animals; Anura; Chickens; Chlorpromazine; Erythrocyte Membrane; Erythrocytes | 1979 |
Inhibition of platelet thrombus formation by chlorpromazine acting to diminish haemolysis.
Topics: Adenosine Diphosphate; Blood Coagulation; Chlorpromazine; Depression, Chemical; Dose-Response Relati | 1979 |
Photobiochemistry in the dark: photohemolysis of red cells sensitized by chlorpromazine-bioenergized triplet acetone system.
Topics: Acetone; Aldehydes; Chlorpromazine; Darkness; Erythrocytes; Hemolysis; Humans; Kinetics; Oxygen Cons | 1979 |
Experiments to illustrate the effect of chlorpromazine on the permeability of the bacterial cell wall.
Topics: Bacteria; Cell Membrane Permeability; Cell Wall; Chlorpromazine; Hemolysis; Staphylococcus aureus | 1979 |
The asymmetric distribution of chlorpromazine and its quaternary analogue over the erythrocyte membrane.
Topics: Chlorpromazine; Erythrocyte Membrane; Erythrocytes; Hemolysis; Humans; In Vitro Techniques; Kinetics | 1977 |
The role of erythrocytes in initial haemostatic plug formation.
Topics: Adenosine; Animals; Arterioles; Blood Platelets; Chlorpromazine; Erythrocytes; Extracorporeal Circul | 1977 |
Effect of drugs on human erythrocytes--4. Protecting effect of dextran on drug-induced hemolysis.
Topics: Chlorpromazine; Clemastine; Dextrans; Diffusion; Erythrocytes; Hemoglobins; Hemolysis; Humans; In Vi | 1978 |
Primary mechanisms of erythrocyte photolysis induced by biological sensitizers and phototoxic drugs.
Topics: Chlorpromazine; Demeclocycline; Erythrocytes; Hematoporphyrins; Hemolysis; Kynurenic Acid; Photolysi | 1975 |
Biological membranes as bilayer couples. III. Compensatory shape changes induced in membranes.
Topics: Adenosine Triphosphate; Animals; Antigen-Antibody Reactions; Azides; Cell Membrane; Chlorpromazine; | 1976 |
Effects of different doses of chlorpromazine on renal function in the dog.
Topics: Animals; Blood Pressure; Chlorpromazine; Dogs; Female; Glomerular Filtration Rate; Hemoglobins; Hemo | 1976 |
Stoichiometry of compounds bound to human erythrocytes in relation to morphology.
Topics: Binding Sites; Chlorpromazine; Erythrocytes; Hemolysis; Humans; Kinetics; Mathematics; Methylene Blu | 1975 |
Effects of chlorpromazine on bilirubin metabolism and biliary secretion in the rat.
Topics: Animals; Bile; Bilirubin; Chlorpromazine; Cholestasis; Heme; Hemolysis; Liver; Male; Rats | 1975 |
Use of microphotohemolysis to distinguish differences in erythrocyte treatments.
Topics: Animals; Chlorpromazine; Dextrans; Diamide; Dose-Response Relationship, Radiation; Erythrocytes; Flu | 1991 |
[The effect of chlorpromazine on the temperature and osmotic sensitivity of erythrocytes].
Topics: Chlorpromazine; Cold Temperature; Erythrocytes; Hemolysis; Humans; Osmosis | 1991 |
Species differences in response to photohemolytic agents.
Topics: Animals; Chlorpromazine; Dogs; Erythrocytes; Free Radical Scavengers; Hemolysis; Humans; In Vitro Te | 1991 |
Stabilizing effects of some amino acids on membranes of rabbit erythrocytes perturbed by chlorpromazine.
Topics: Amino Acids; Animals; Aspartic Acid; Chlorpromazine; Erythrocyte Membrane; Glycine; Half-Life; Hemol | 1989 |
Effects of purines and forskolin on haemolysis.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Anesthetics, Loca | 1987 |
Influence of chlorpromazine on the transverse mobility of phospholipids in the human erythrocyte membrane: relation to shape changes.
Topics: Chlorpromazine; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Erythrocytes; Hemolysis; | 1988 |
Influence of dietary lipids on the effect of chlorpromazine on membrane properties of rabbit red cells.
Topics: Animals; Chlorpromazine; Dietary Fats; Erythrocyte Deformability; Erythrocyte Membrane; Hemolysis; I | 1986 |
Entrapping of the spin label tempocholine into human erythrocytes by resealing after hyposmolar stress. Comparison with haemolysis. The effects of some membrane-active substances.
Topics: Calcium; Calmodulin; Chlorpromazine; Cyclic N-Oxides; Edetic Acid; Electron Spin Resonance Spectrosc | 1985 |
Trifluoperazine inhibits Sendai virus-induced hemolysis.
Topics: Animals; Chick Embryo; Chlorpromazine; Erythrocyte Membrane; Erythrocytes; Hemolysis; Humans; Kineti | 1986 |
Differential effects of chlorpromazine on secretion, protein phosphorylation and phosphoinositide metabolism in stimulated platelets.
Topics: Blood Platelets; Blood Proteins; Chlorpromazine; Dose-Response Relationship, Drug; Hemolysis; Humans | 1986 |
Application of differential flow microcalorimetry for study of drug interactions in the blood system.
Topics: Blood Proteins; Calorimetry, Differential Scanning; Chlorpromazine; Erythrocyte Membrane; Erythrocyt | 1988 |
Stimulation by trifluoperazine of p-aminohippurate accumulation in rat kidney cortical slices.
Topics: Adenosine Triphosphate; Aminohippuric Acids; Animals; Chlorpromazine; Dibucaine; Hemolysis; In Vitro | 1987 |
Tests for local toxicity of intramuscular drug preparations: comparison of in vivo and in vitro methods.
Topics: Animals; Chlorpromazine; Clopenthixol; Creatine Kinase; Digoxin; Female; Hemolysis; In Vitro Techniq | 1985 |
The effect of nervous active drugs on MG ++ -dependent ATPase in erythrocyte membrane.
Topics: Adenosine Triphosphatases; Atropine; Cell Membrane; Chlorpromazine; Enzyme Activation; Ephedrine; Er | 1971 |
Effect of beta-carotene on photohemolysis.
Topics: Adult; Carotenoids; Chlorpromazine; Demeclocycline; Erythrocytes; Hemolysis; Humans; In Vitro Techni | 1973 |
Temperature-dependent reaction of flufenamic acid with rat erythrocyte membrane.
Topics: Anesthetics, Local; Animals; Anti-Inflammatory Agents; Cell Membrane; Chlorpromazine; Dose-Response | 1973 |
Interactions of membrane stabilizing drugs affecting human erythrocytes in vitro.
Topics: Acetanilides; Adrenergic beta-Antagonists; Amino Alcohols; Chlorpromazine; Diazepam; Dose-Response R | 1973 |
[Studies on the lysolecithin-metabolizing enzymes of intact erythrocytes and modified stromas].
Topics: Acyltransferases; Adenosine Triphosphate; Amitriptyline; Antibodies; Cell Membrane; Chlorpromazine; | 1968 |
The structure-activity relationship of tricyclic amines.
Topics: Adenosine Triphosphatases; Amines; Chemical Phenomena; Chemistry; Chloroform; Chlorpromazine; Erythr | 1971 |
Detection of chlorpromazine and thioridazine metabolites in human erythrocytes.
Topics: Chlorpromazine; Chromatography, Thin Layer; Erythrocytes; Hemolysis; Humans; Indicators and Reagents | 1969 |
Drug allergy. II.
Topics: Aged; Anemia, Hemolytic; Antigen-Antibody Reactions; Blood Platelets; Chlorpromazine; Dermatitis, Co | 1971 |
Hemolysis of erythrocytes by primary pharmacologic agents.
Topics: Animals; Brompheniramine; Chlordiazepoxide; Chlorpromazine; Diphenhydramine; Doxapram; Erythrocytes; | 1971 |
Cellular mechanisms of chlorpromazine photosensitivity.
Topics: Cell Membrane; Cell Survival; Cells, Cultured; Chlorpromazine; Erythrocytes; Hemolysis; Humans; Ligh | 1974 |
Biological membranes as bilayer couples. A molecular mechanism of drug-erythrocyte interactions.
Topics: Binding Sites; Cell Membrane; Cell Membrane Permeability; Chlorpromazine; Erythrocytes; Hemolysis; H | 1974 |
The hemolytic effect of some phenothiazine derivatives in vitro and in vivo.
Topics: Animals; Cell Membrane Permeability; Chlorpromazine; Dogs; Erythrocytes; Glucose; Hemoglobins; Hemol | 1972 |
New approaches to investigating UVL photo protective substances in vitro.
Topics: 1-Propanol; Aminobenzoates; Aniline Compounds; beta-Aminoethyl Isothiourea; Candida albicans; Chlorp | 1973 |
[Two devices for perfusion of isolated rat brain].
Topics: Absorption; Animals; Brain; Chlorpromazine; Electroencephalography; Filtration; Hemolysis; Male; Met | 1972 |
Inhibition of hemolysis by tricyclic dyestuffs--fluorescein-phenothiazine antagonism.
Topics: Anemia, Hemolytic; Chlorpromazine; Coloring Agents; Erythrocytes; Fluoresceins; Hemolysis; Humans; I | 1973 |
[Physiopathological aspects of immunohemolysis and its inhibition].
Topics: Antigen-Antibody Reactions; Binding Sites, Antibody; Cell Membrane; Chlorpromazine; Cold Temperature | 1973 |
Binding of phenothiazines to proteins--measurement of binding based on the inhibition of the hemolytic activity of phenothiazines on sheep red blood cells.
Topics: Animals; Blood Proteins; Cattle; Chickens; Chlorpromazine; Dogs; Erythrocytes; Hemolysis; Humans; Hy | 1973 |
Ultraviolet light protection by several new compounds.
Topics: Administration, Topical; Aminobenzoates; Anthracenes; Antioxidants; beta-Aminoethyl Isothiourea; Bro | 1974 |
Acetylcholine esterase as a probe for erythrocyte-membrane intactness.
Topics: Acetylcholinesterase; Cell Membrane; Chlorpromazine; Erythrocytes; Evaluation Studies as Topic; Hemo | 1974 |
Effect of phenothiazine drugs on the stability of rat liver subcellular particles.
Topics: Acclimatization; Acid Phosphatase; Adenosine Triphosphate; Animals; Body Temperature; Chlorpromazine | 1974 |
A new prolonged-acting type of chlorpromazine: behavioral effects and prolonged actions on nerve membranes.
Topics: Amphetamine; Animals; Anura; Behavior, Animal; Biopharmaceutics; Carbon Radioisotopes; Cell Membrane | 1974 |
Membrane expansion of erythrocyte ghosts by tranquilizers and anesthetics.
Topics: Alcohols; Cell Membrane; Chlorpromazine; Erythrocytes; Hematocrit; Hemolysis; Humans; In Vitro Techn | 1969 |
The haemolytic effect of some phenothiazine derivatives.
Topics: Animals; Anticoagulants; Blood Platelets; Cell Membrane Permeability; Chlorpromazine; Citrates; Colo | 1965 |
Anesthetics expand erythrocyte membranes without causing loss of K + .
Topics: Alcohols; Anesthetics, Local; Biological Transport; Cell Membrane; Chlorpromazine; Erythrocytes; Fat | 1972 |
The membrane concentrations of neutral and positive anesthetics (alcohols, chlorpromazine, morphine) fit the Meyer-Overton rule of anesthesia; negative narcotics do not.
Topics: Alcohols; Anesthetics; Animals; Barbiturates; Carbon Isotopes; Cell Membrane; Chlorpromazine; Erythr | 1972 |
[Topical effect of sedatives and prednisolone succinate on osmotic and immune hemolysis].
Topics: Cell Membrane; Chlorpromazine; Erythrocytes; Haloperidol; Hemagglutination Inhibition Tests; Hemolys | 1972 |
Effect of drugs on the hemolysis of rat erythrocytes.
Topics: Animals; Aspirin; Bile Acids and Salts; Chlordiazepoxide; Chloroquine; Chlorpromazine; Chlorprothixe | 1969 |
Effect of drugs on red cell fragility.
Topics: Acetylcholine; Amobarbital; Amphetamine; Atropine; Barbiturates; Bemegride; Cell Membrane; Chlorprom | 1970 |
The influence of ATP Riboflavin, Succinate, and Glutamate in vitro on the haemolytic action of Chlorpromazine.
Topics: Adenosine Triphosphate; Animals; Cattle; Chlorpromazine; Erythrocytes; Glutamates; Hemolysis; Method | 1970 |
Membrane stabilization and cardiac effects of d,1-propranolol, d-propranolol and chlorpromazine.
Topics: Animals; Cell Membrane; Chlorpromazine; Coronary Vessels; Depression, Chemical; Erythrocytes; Female | 1970 |
The effects of phenothiazines on human erythrocytes: an ultrastructural study.
Topics: Cell Membrane; Chlorpromazine; Erythrocytes; Hemolysis; Humans; In Vitro Techniques; Microscopy, Ele | 1971 |
Effect of phenothiazine on the red cells of paroxysmal nocturnal haemoglobinuria.
Topics: Animals; Blood Transfusion; Cell Membrane; Chlorpromazine; Chromium Isotopes; Erythrocytes; Hemoglob | 1968 |
The effects of beta-diethylaminoethyl-diphenylpropylacetate (SKE 525-A) on biological membranes. I. SKF 525-A-induced stabilization of human erythrocytes.
Topics: Cell Membrane; Chlorpromazine; Erythrocytes; Hemolysis; Humans; Hydrogen-Ion Concentration; Osmolar | 1968 |
The influence of chlorpromazine on human erythrocytes.
Topics: Blood Sedimentation; Cell Membrane; Chlorpromazine; Erythrocytes; Hematocrit; Hemolysis; Humans; Iso | 1968 |
Membrane expansion of intact erythrocytes by anesthetics.
Topics: Alcohols; Anesthetics; Cell Membrane; Chlorpromazine; Erythrocytes; Hematocrit; Hemolysis; Humans; I | 1969 |
Membrane expansion of the erythrocyte by both the neutral and ionized forms of chlorpromazine.
Topics: Cell Membrane; Chlorpromazine; Erythrocytes; Hemolysis; Humans; Hydrogen-Ion Concentration; In Vitro | 1969 |
[Hemolytic stability of erythrocytes in schizophrenia].
Topics: Chlorpromazine; Erythrocytes; Hemolysis; Humans; Schizophrenia | 1965 |
5-Hydroxytryptamine release from blood platelets and haemolysis of red blood cells of rabbit induced by phenothiazines and related compounds.
Topics: Animals; Blood Platelets; Chlorpromazine; Erythrocytes; Hemolysis; Male; Phenothiazines; Rabbits; Re | 1966 |