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chlorpromazine and Heart Failure

chlorpromazine has been researched along with Heart Failure in 23 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"The intravenous administration of chlorpromazine in 12 patients with acute myocardial infarction and altered pump function was followed by a significant reduction in systemic vascular resistance (28."7.65Hemodynamic effects of chlorpromazine in patients with acute myocardial infarction and pump failure. ( Elkayam, U; Geller, E; Laniado, S; Rotmensch, HH; Terdiman, R, 1977)
" The ventricular arrhythmias responded to intravenous administration of lidocaine and to direct current electric shock; ventricular pacing was required in some instances and intravenous administration of propranolol combined with ventricular pacing in one."3.65Electrocardiographic changes and cardiac arrhythmias in patients receiving psychotropic drugs. ( Chou, TC; Fowler, NO; Hanenson, IB; Holmes, JC; McCall, D, 1976)
"The intravenous administration of chlorpromazine in 12 patients with acute myocardial infarction and altered pump function was followed by a significant reduction in systemic vascular resistance (28."3.65Hemodynamic effects of chlorpromazine in patients with acute myocardial infarction and pump failure. ( Elkayam, U; Geller, E; Laniado, S; Rotmensch, HH; Terdiman, R, 1977)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199023 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
MEIER, R1
BRUNI, C1
TRIPOD, J1
CAVAZZUTI, F1
CRISTINI, M1
SZABO, G2
SOLTI, F2
REV, J2
MEGYESI, K2
COHEN, AM1
KARBAAT, J1
MACREZ, C1
LUCHERINI, M1
MELCHIORRI, P1
Romano, E2
Gullo, A2
Blakeley, C1
Tinker, J1
Mocavero, G1
Elkayam, U2
Frishman, W1
Ueda, K2
Mifune, J2
Inoue, H2
Sugiura, M1
Murakami, M2
López, M1
da Silva, OA1
Amaral, CF1
Lopes, JA1
da Silveira, JC1
Fonseca, JG1
de Oliveira, JS1
Cardini, JF1
Fowler, NO1
McCall, D1
Chou, TC1
Holmes, JC1
Hanenson, IB1
Kuramoto, K1
Matsushita, S1
Kuwajima, I1
Sakai, M1
Iwasaki, T1
Shinagawa, T1
Rotmensch, HH1
Terdiman, R1
Geller, E1
Laniado, S1
Clauss, RH1
Ray, JF1
Lambotte, L1
Rocmans, P1
Bellina, JH1
Bickers, JN1
Beard, J1
Feola, M1
Haiderer, O1
Kennedy, JH1
Askrog, VF1
Dam, WH1
Hagelsten, JO1

Reviews

4 reviews available for chlorpromazine and Heart Failure

ArticleYear
Vasodilators in acute circulatory failure.
    Intensive care medicine, 1983, Volume: 9, Issue:1

    Topics: Albuterol; Captopril; Chlorpromazine; Heart Failure; Humans; Isosorbide Dinitrate; Nitroglycerin; Ni

1983
Cardiovascular effects of phenothiazines.
    American heart journal, 1980, Volume: 100, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Cardiopulmonary Bypass; Cardi

1980
Pharmacologic assistance to the failing circulation.
    Surgery, gynecology & obstetrics, 1968, Volume: 126, Issue:3

    Topics: Adenosine Triphosphatases; Aminophylline; Angiotensin II; Blood Gas Analysis; Blood Pressure; Cardia

1968
Venous pressure and other thoughts.
    Proceedings of the Royal Society of Medicine, 1969, Jul-07, Volume: 62, Issue:7

    Topics: Anesthesia; Blood Pressure; Blood Volume Determination; Cardiac Output; Catecholamines; Chlorpromazi

1969

Trials

1 trial available for chlorpromazine and Heart Failure

ArticleYear
Treatment of acute left-sided heart failure with intramuscular injection of chlorpromazine.
    Japanese heart journal, 1979, Volume: 20, Issue:1

    Topics: Aged; Blood Pressure; Cardiac Output; Chlorpromazine; Clinical Trials as Topic; Female; Heart Failur

1979

Other Studies

18 other studies available for chlorpromazine and Heart Failure

ArticleYear
[Pharmacodynamic differentiation of apresoline, serpasil and chlorpromazine by their effect on water retention in the rat].
    Archives internationales de pharmacodynamie et de therapie, 1955, Dec-01, Volume: 104, Issue:2

    Topics: Animals; Antihypertensive Agents; Chlorpromazine; Heart Failure; Hydralazine; Kidney; Rats; Reserpin

1955
[Neuroplegic drugs in the reparative treatment of cardiac decompensation].
    Atti della Societa italiana di cardiologia, 1956, Volume: 1

    Topics: Chlorpromazine; Heart Failure

1956
Effect of chlorpromazine on renal haemodynamics and function in congestive heart failure; preliminary report.
    British medical journal, 1957, Apr-13, Volume: 1, Issue:5023

    Topics: Chlorpromazine; Heart Failure; Hemodynamics; Humans; Kidney

1957
[Effect of chlorpromazine (largactil) on renal function in edematous cardiac patients].
    Acta medica Academiae Scientiarum Hungaricae, 1957, Volume: 10, Issue:3

    Topics: Chlorpromazine; Edema; Edema, Cardiac; Heart Failure; Humans; Kidney

1957
Diuretic effect of chlorpromazine in patients with congestive heart failure.
    American heart journal, 1957, Volume: 54, Issue:6

    Topics: Body Fluids; Chlorpromazine; Diuresis; Diuretics; Heart Failure; Humans; Water-Electrolyte Balance

1957
[A case of death caused by the administration of chlorpromazine (largactil)].
    Nederlands militair geneeskundig tijdschrift, 1960, Volume: 13

    Topics: Chlorpromazine; Death; Heart Failure

1960
[TREATMENT OF CARDIAC INSUFFICIENCY].
    Les Cahiers du College de medecine des hopitaux de Paris, 1963, Dec-30, Volume: 4

    Topics: Anticoagulants; Bloodletting; Cardiac Glycosides; Chlorpromazine; Diet, Sodium-Restricted; Heart Fai

1963
ANGIOCARDIOGRAPHIC EVIDENCE FOR HEART FAILURE IN ADRENALIN PULMONARY EDEMA IN RABBITS.
    Cardiologia, 1964, Volume: 45

    Topics: Angiocardiography; Angiotensins; Animals; Chlorpromazine; Dibenzylchlorethamine; Electrocardiography

1964
Chlorpromazine and frusemide in treatment of acute left-ventricular failure.
    Lancet (London, England), 1980, May-10, Volume: 1, Issue:8176

    Topics: Acute Disease; Aged; Blood Pressure; Carbon Dioxide; Chlorpromazine; Drug Therapy, Combination; Furo

1980
[Acute pulmonary edema. Clinical experience in re-evaluation of the therapeutic role of chlorpromazine].
    Minerva anestesiologica, 1981, Volume: 47, Issue:6

    Topics: Aged; Chlorpromazine; Heart Diseases; Heart Failure; Humans; Intermittent Positive-Pressure Ventilat

1981
Influence of vasodilator therapy on prognosis of acute myocardial infarction in the aged patients. A comparative study between vasodilator-treated group and group treated without vasodilator.
    Japanese heart journal, 1980, Volume: 21, Issue:1

    Topics: Age Factors; Aged; Chlorpromazine; Female; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate

1980
[Treatment of low output syndrome in chronic Chagas cardiopathy].
    Arquivos brasileiros de cardiologia, 1980, Volume: 34, Issue:3

    Topics: Adolescent; Adult; Cardiac Output, Low; Chagas Cardiomyopathy; Chlorpromazine; Female; Furosemide; H

1980
Electrocardiographic changes and cardiac arrhythmias in patients receiving psychotropic drugs.
    The American journal of cardiology, 1976, Volume: 37, Issue:2

    Topics: Adrenergic Agonists; Adult; Aged; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Cardiovasc

1976
Hemodynamic effects of chlorpromazine in patients with acute myocardial infarction and pump failure.
    Chest, 1977, Volume: 72, Issue:5

    Topics: Acute Disease; Aged; Blood Pressure; Cardiac Output; Chlorpromazine; Female; Heart Failure; Heart Ra

1977
[Toxi-infectious shock].
    Acta chirurgica Belgica, 1973, Volume: 72, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; Blood Transfusion; Chlorpromazine; Digitalis G

1973
Modern management of sickle cell disease in pregnancy.
    Southern medical journal, 1974, Volume: 67, Issue:4

    Topics: Abortion, Spontaneous; Anemia, Sickle Cell; Black or African American; Blood Transfusion; Blood Visc

1974
Experimental graded "pump failure" of the left ventricle.
    The Journal of surgical research, 1971, Volume: 11, Issue:7

    Topics: Animals; Aorta, Thoracic; Blood Flow Velocity; Blood Pressure; Carbon Dioxide; Cardiac Output; Cardi

1971
Treatment of patients with pulmonary oedema in an intensive therapy department.
    British journal of anaesthesia, 1967, Volume: 39, Issue:3

    Topics: Aged; Chlorpromazine; Coronary Disease; Digitalis Glycosides; Diuretics; Electrocardiography; Female

1967