Page last updated: 2024-10-25

chlorpromazine and Heart Defects, Congenital

chlorpromazine has been researched along with Heart Defects, Congenital in 7 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Heart Defects, Congenital: Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.

Research Excerpts

ExcerptRelevanceReference
"A girl had cleft palate, micrognathia, Wormian bones, congenital heart disease, dislocated hips, absent tibiae, bowed fibulae, preaxial polydactyly of the feet, and abnormal dermal patterns at birth."1.25Congenital malformations. Cleft palate, congenital heart disease, absent tibiae, and polydactyly. ( Ho, CK; Kaufman, RL; McAlister, WH, 1975)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19906 (85.71)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
VECKO, J1
Itou, M1
Okamoto, H1
Suwa, J1
Asou, T1
Hoka, S1
Ho, CK1
Kaufman, RL1
McAlister, WH1
Tonczar, L1
Rochowanski, E1
Pokorny, W1
Probst, P1
Shapiro, IuL1
Vaĭntrub, MIa1
Grinberg, KN1
Zhurkov, VS1
Farkas, G2
Fujikura, I1
Anzai, N1
Ito, T1
Kurosawa, H1

Reviews

1 review available for chlorpromazine and Heart Defects, Congenital

ArticleYear
[Teratogenic and mutagenic effects of anticonvulsive and psychotropic drugs (review of the literature)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1972, Volume: 72, Issue:6

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Anticonvulsants; Antidepressive Agent

1972

Trials

1 trial available for chlorpromazine and Heart Defects, Congenital

ArticleYear
[Application of a PDE III inhibitor, olprinone, for fast track pediatric cardiac surgery].
    Masui. The Japanese journal of anesthesiology, 2004, Volume: 53, Issue:3

    Topics: Cardiac Surgical Procedures; Cardiopulmonary Bypass; Child; Child, Preschool; Chlorpromazine; Heart

2004

Other Studies

5 other studies available for chlorpromazine and Heart Defects, Congenital

ArticleYear
[GENERAL ANESTHESIA IN CARDIAC CATHETERIZATION IN CHILDREN].
    Sbornik vedeckych praci Lekarske fakulty Karlovy university v Hradci Kralove, 1963, Volume: 6

    Topics: Adolescent; Anesthesia, General; Cardiac Catheterization; Child; Chlorpromazine; Halothane; Heart De

1963
Congenital malformations. Cleft palate, congenital heart disease, absent tibiae, and polydactyly.
    American journal of diseases of children (1960), 1975, Volume: 129, Issue:6

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Chloramines; Chlorpromazine; Cleft Palate; Dip

1975
[Bloodgas changes during heart catheterisation in children under basal sedation (author' transl)].
    Der Anaesthesist, 1975, Volume: 24, Issue:4

    Topics: Acid-Base Equilibrium; Analgesics; Cardiac Catheterization; Child; Child, Preschool; Chlorpromazine;

1975
[Teratogenic effects of hyperemesis gravidarum and of the customary drugs used in its therapy].
    Zentralblatt fur Gynakologie, 1971, Mar-06, Volume: 93, Issue:10

    Topics: Abnormalities, Drug-Induced; Chlorpromazine; Clubfoot; Congenital Abnormalities; Female; Heart Defec

1971
[Open-heart surgery with heart-lung bypass].
    Iryo, 1972, Volume: 26, Issue:3

    Topics: Adolescent; Anesthesia; Child; Chlorpromazine; Extracorporeal Circulation; Halothane; Heart Defects,

1972