chlorpromazine has been researched along with HbS Disease in 11 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bepridil did not inhibit intracellular hemoglobin S polymerization even at 200 microM, as shown by oxygen scan ektacytometry." | 1.29 | Bepridil as an antisickling agent: membrane internalization and cell rigidity. ( Acquaye, C; Féo, C; Johnson, RM; Sarnaik, S, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (81.82) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ohnishi, ST | 4 |
| Sato, T | 1 |
| Smith, JE | 1 |
| Mohandas, N | 1 |
| Clark, MR | 1 |
| Greenquist, AC | 1 |
| Shohet, SB | 1 |
| Pfafferott, C | 1 |
| Wenby, R | 1 |
| Meiselman, HJ | 1 |
| Thompson, AA | 1 |
| Cornelius, AS | 1 |
| Asakura, T | 1 |
| Horiuchi, K | 2 |
| Johnson, RM | 1 |
| Acquaye, C | 1 |
| Féo, C | 1 |
| Sarnaik, S | 1 |
| Horiuchi, KY | 1 |
| Karayalcin, G | 1 |
| Imran, M | 1 |
| Rosner, F | 1 |
| Bellina, JH | 1 |
| Bickers, JN | 1 |
| Knight, R | 1 |
| Woodruff, AW | 1 |
| Pettitt, LE | 1 |
11 other studies available for chlorpromazine and HbS Disease
| Article | Year |
|---|---|
Antisickling effects of membrane-interacting compounds.
Topics: Anemia, Sickle Cell; Antipsychotic Agents; Antisickling Agents; Calmodulin; Chlorpromazine; Erythroc | 1982 |
Effects of sulfhydryl reagents on the anti-sickling activity of some membrane-interacting compounds.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Chlorpromazine; Erythrocytes; Ethylmaleimide; Human | 1983 |
Deformability and spectrin properties in three types of elongated red cells.
Topics: Anemia, Sickle Cell; Animals; Camelids, New World; Chlorpromazine; Erythrocytes; Hemolysis; Humans; | 1980 |
Morphologic and internal viscosity aspects of RBC rheologic behavior.
Topics: Adenosine Triphosphate; Anemia, Sickle Cell; Blood Viscosity; Chlorpromazine; Dinitrobenzenes; Eryth | 1982 |
Viscosity and filtrability measurements of sickle-cell suspensions in the development of anti-sickling drugs.
Topics: Anemia, Sickle Cell; Antisickling Agents; Blood Viscosity; Chlorpromazine; Erythrocytes, Abnormal; H | 1982 |
Comparative studies of phenothiazine derivatives for their effects on swelling of normal and sickle erythrocytes.
Topics: Adult; Anemia, Sickle Cell; Antipsychotic Agents; Antisickling Agents; Calmodulin; Chlorpromazine; E | 1993 |
Bepridil as an antisickling agent: membrane internalization and cell rigidity.
Topics: Anemia, Sickle Cell; Antisickling Agents; Bepridil; Chlorpromazine; Endocytosis; Erythrocyte Count; | 1994 |
The mechanism of in vitro formation of irreversibly sickled cells and modes of action of its inhibitors.
Topics: Adenosine Triphosphate; Adult; Anemia, Sickle Cell; Calcium; Cell Separation; Chlorpromazine; Erythr | 1986 |
Priapism in sickle cell disease: report of five cases.
Topics: Adult; Anemia, Sickle Cell; Blood Transfusion; Chlorpromazine; Codeine; Diethylstilbestrol; Drainage | 1972 |
Modern management of sickle cell disease in pregnancy.
Topics: Abortion, Spontaneous; Anemia, Sickle Cell; Black or African American; Blood Transfusion; Blood Visc | 1974 |
Some applications of radiochromium 51Cr in assessing the value of therapeutic regimes and the effects of crises in haemoglobinopathic states.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Bicarbonates; Blood Chemical Analysis; Child; Chlorpromazine | 1968 |