chlorpromazine has been researched along with Glomerulonephritis in 9 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Glomerulonephritis: Inflammation of the renal glomeruli (KIDNEY GLOMERULUS) that can be classified by the type of glomerular injuries including antibody deposition, complement activation, cellular proliferation, and glomerulosclerosis. These structural and functional abnormalities usually lead to HEMATURIA; PROTEINURIA; HYPERTENSION; and RENAL INSUFFICIENCY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chlorpromazine blocks antibody-mediated redistribution of cell surface antigens in vitro and in vivo and inhibits the development of passive Heymann glomerulonephritis, a disease characterized by in situ formation of immune complexes (Camussi et al J Immunol 1986, 136:2127-2135)." | 7.67 | Effect of chlorpromazine on the development of experimental glomerulonephritis and Arthus reaction. ( Andres, G; Brentjens, J; Camussi, G; Niesen, N; Salvidio, G, 1988) |
| "The effect of chlorpromazine, one of several calmodulin antagonists that inhibit cytoskeletal movement, on the local kinetics of injected proteinuria-inducing MoAb 5-1-6 was examined to test the hypothesis that proteinuria is inhibited if the antigen recognized by MoAb 5-1-6 or injected MoAb remains on the surface of epithelial foot processes." | 3.68 | Effect of chlorpromazine on kinetics of injected monoclonal antibody in MoAb-induced glomerular injury. ( Arakawa, M; Kawachi, H; Nishi, S; Oite, T; Shimizu, F; Takashima, N, 1993) |
| "Chlorpromazine blocks antibody-mediated redistribution of cell surface antigens in vitro and in vivo and inhibits the development of passive Heymann glomerulonephritis, a disease characterized by in situ formation of immune complexes (Camussi et al J Immunol 1986, 136:2127-2135)." | 3.67 | Effect of chlorpromazine on the development of experimental glomerulonephritis and Arthus reaction. ( Andres, G; Brentjens, J; Camussi, G; Niesen, N; Salvidio, G, 1988) |
| "Chlorpromazine treatment prevented both the cell proliferation and the brush border loss produced by divalent antibodies, although clumping of microvilli was not prevented." | 1.27 | Antibody-mediated proliferation of proximal tubule cells requires cross-linking of antigenic determinants. ( Brodkin, M; Noble, B, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (88.89) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| HIRSCH, S | 1 |
| VISENTIN, G | 1 |
| MALOSSI, M | 2 |
| Takashima, N | 1 |
| Kawachi, H | 1 |
| Oite, T | 1 |
| Nishi, S | 1 |
| Arakawa, M | 1 |
| Shimizu, F | 1 |
| Brodkin, M | 1 |
| Noble, B | 2 |
| Camussi, G | 2 |
| Salvidio, G | 1 |
| Niesen, N | 1 |
| Brentjens, J | 1 |
| Andres, G | 2 |
| Van Liew, J | 1 |
| Brentjens, JR | 1 |
| Marchesoni, C | 1 |
| Melchiori, G | 1 |
| Fruet, G | 1 |
| Malossi, R | 1 |
| Giacomoni, C | 1 |
| Enger, E | 1 |
9 other studies available for chlorpromazine and Glomerulonephritis
| Article | Year |
|---|---|
[Pulmonary edema during the course of acute glomerulonephritis treated with chlorpromazine].
Topics: Acute Disease; Chlorpromazine; Edema; Glomerulonephritis; Humans; Pulmonary Edema | 1960 |
[Results obtained by means of the treatment of acute diffuse glomerulonephritis in the oliguric phase with chlopromazine].
Topics: Acute Disease; Chlorpromazine; Glomerulonephritis; Humans | 1961 |
[Usefulness of chlorpromazine treatment in acute diffuse glomerulonephritis in infancy in reference to the permeability of the blood vessels].
Topics: Acute Disease; Capillary Permeability; Chlorpromazine; Glomerulonephritis; Humans; Permeability | 1962 |
Effect of chlorpromazine on kinetics of injected monoclonal antibody in MoAb-induced glomerular injury.
Topics: Animals; Antibodies, Monoclonal; Chlorpromazine; Female; Fluorescent Antibody Technique; Glomerulone | 1993 |
Antibody-mediated proliferation of proximal tubule cells requires cross-linking of antigenic determinants.
Topics: Animals; Chlorpromazine; Epitopes; Female; Fluorescent Antibody Technique; Glomerulonephritis; Immun | 1988 |
Effect of chlorpromazine on the development of experimental glomerulonephritis and Arthus reaction.
Topics: Animals; Antigens; Arthus Reaction; Chlorpromazine; Fluorescent Antibody Technique; Glomerulonephrit | 1988 |
Pathogenesis of passive Heymann glomerulonephritis: chlorpromazine inhibits antibody-mediated redistribution of cell surface antigens and prevents development of the disease.
Topics: Animals; Antigen-Antibody Complex; Antigens, Surface; Cells, Cultured; Chlorpromazine; Complement Ac | 1986 |
[Acute post-infectious glomerulonephritis. Pathogenetic considerations and clinical results of using chlorpromazine].
Topics: Acute Disease; Adolescent; Child; Child, Preschool; Chlorpromazine; Drug Evaluation; Glomerulonephri | 1986 |
[Therapy of hypertensive crises].
Topics: Antihypertensive Agents; Chlorpromazine; Glomerulonephritis; Humans; Hypertension, Renal; Intensive | 1968 |