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chlorpromazine and Gastroduodenal Ulcer

chlorpromazine has been researched along with Gastroduodenal Ulcer in 26 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Research Excerpts

ExcerptRelevanceReference
" Eventual discontinuation of cimetidine therapy led to a return of schizophrenic symptoms, which responded to an increase in chlorpromazine dosage to previous levels."5.28Adverse interaction between cimetidine and chlorpromazine in two cases of chronic schizophrenia. ( Byrne, A; O'Shea, B, 1989)
"Chlorpromazine did not inhibit lesions formed after combining indomethacin with insulin in a dose of 3 IU/kg."1.28Effect of chlorpromazine on ulcer formation by indomethacin in histamine- and insulin-stimulated rats. ( Kohút, A; Mirossay, L; Nicák, A, 1991)
" Eventual discontinuation of cimetidine therapy led to a return of schizophrenic symptoms, which responded to an increase in chlorpromazine dosage to previous levels."1.28Adverse interaction between cimetidine and chlorpromazine in two cases of chronic schizophrenia. ( Byrne, A; O'Shea, B, 1989)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199025 (96.15)18.7374
1990's1 (3.85)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
GABLE, JJ1
KEYRILAINEN, TO1
KALLIOMAKI, JL1
GRONROOS, M1
SUN, DC1
SHAY, H1
SCARPONI, E1
NORBIATO, L1
SOCHA, P1
KUHN, E2
WEISS, Z1
BUCHEL, L3
GALLAIRE, D2
TUBARO, E1
KONTUREK, S1
RADECKI, T1
SELMECI, L1
TOTH, T1
METYSOVA, J1
METYS, J1
VOTAVA, Z1
Harada, M1
Mayuzumi, K1
Yano, S1
Mirossay, L1
Kohút, A1
Nicák, A1
Byrne, A1
O'Shea, B1
Lévy, J1
Moczurad, K1
Lemke, H1
Oettel, M1
Chemnitius, KH1
Nagura, M1
Caprino, L1
Borrelli, F1
Falchetti, R1
Chrostowski, K1
Jeske, J1
Summers, RW1
Kent, TH1
Osborne, JW1
Brodie, DA1
Cook, PG1
Bauer, BJ1
Dagle, GE1
Dvorák, V1
Zamrazil, V1
Liblau, L1
Murawsky, M1
Prioux-Guyonneau, M1

Reviews

2 reviews available for chlorpromazine and Gastroduodenal Ulcer

ArticleYear
PROTEIN METABOLISM DURING THERAPEUTIC SLEEP.
    Psychiatria et neurologia, 1963, Volume: 146

    Topics: Barbiturates; Chlorpromazine; Conditioning, Classical; Humans; Narcotherapy; Neurotic Disorders; Nit

1963
[DRUGS ON DISPLAY].
    Bollettino chimico farmaceutico, 1963, Volume: 102

    Topics: Antihypertensive Agents; Antineoplastic Agents; Chlorpromazine; Chlorprothixene; Coumarins; Peptic U

1963

Other Studies

24 other studies available for chlorpromazine and Gastroduodenal Ulcer

ArticleYear
Jaundice associated with chlorpromazine therapy and peptic ulcer: report of two cases.
    Southern medical journal, 1955, Volume: 48, Issue:8

    Topics: Chlorpromazine; Jaundice; Peptic Ulcer

1955
Effects of reserpine and chlorpromazine on the Shay rat.
    Annales medicinae experimentalis et biologiae Fenniae, 1957, Volume: 35, Issue:4

    Topics: Animals; Chlorpromazine; Gastric Juice; Peptic Ulcer; Rats; Reserpine

1957
Synergistic action of chlorpromazine and tricyclamol on basal gastric secretion in duodenal ulcer patients.
    Gastroenterology, 1959, Volume: 36, Issue:2

    Topics: Chlorpromazine; Digestion; Duodenal Ulcer; Gastric Juice; Peptic Ulcer; Procyclidine; Trihexyphenidy

1959
[Peptic ulcer].
    Minerva medica, 1959, Jun-06, Volume: 50, Issue:45

    Topics: Chlorpromazine; Humans; Peptic Ulcer

1959
[The use of phenothiazine derivatives in stationary intestinal ulcer cure].
    Medizinische Klinik, 1959, Dec-25, Volume: 54

    Topics: Antipsychotic Agents; Chlorpromazine; Intestinal Diseases; Peptic Ulcer; Phenothiazines; Ulcer

1959
[STOMACH SURGERY UNDER LOCAL ANESTHESIA WITH NEUROPLEGIC PREMEDICATION].
    Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti, 1963, Volume: 42

    Topics: Adjuvants, Anesthesia; Anesthesia, Local; Chlorpromazine; Ephedrine; Humans; Meperidine; Peptic Ulce

1963
[REDUCTION OF DURATION OF CONSTRAINT FOR THE PRODUCTION OF EXPERIMENTAL ULCERS IN RATS. APPLICATION TO THE STUDY OF PROTECTIVE SUBSTANCES].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1963, Nov-15, Volume: 157

    Topics: Atropine; Chlorpromazine; Muscle Relaxants, Central; Peptic Ulcer; Pharmacology; Rats; Research; Str

1963
[CONTRIBUTION OF THE STUDY OF THE EFFECT OF THERAPEUTIC SLEEP ON METABOLISM. 4. EFFECT OF THERAPEUTIC SLEEP ON PROTEIN METABOLISM: C) CHANGES IN NITROGEN UTILIZATION].
    Casopis lekaru ceskych, 1964, Jan-31, Volume: 103

    Topics: Barbiturates; Biomedical Research; Chlorpromazine; Conditioning, Classical; Diet; Diet Therapy; Diet

1964
[EFFECT OF LARGACTIL AND PHENERGAN ON GASTRIC SECRETION AND DEVELOPMENT OF EXPERIMENTAL PEPTIC ULCER].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1964, Feb-17, Volume: 19

    Topics: Biomedical Research; Chlorpromazine; Gastric Acidity Determination; Gastric Juice; Peptic Ulcer; Pha

1964
INFLUENCE OF COMBINED ATROPINE-CHLORBROMAZINE TREATMENT ON RESERPINE-INDUCED GASTRIC ULCER.
    Acta physiologica Academiae Scientiarum Hungaricae, 1964, Volume: 25

    Topics: Anti-Allergic Agents; Atropine; Chlorpromazine; Gastric Juice; Histamine H1 Antagonists; Peptic Ulce

1964
ATTEMPT TO DIFFERENTIATE THYMOLEPTICS AND NEUROLEPTICS BY MEANS OF THEIR INFLUENCE ON THE EFFECTS OF RESERPINE.
    International journal of neuropharmacology, 1964, Volume: 3

    Topics: Amitriptyline; Antidepressive Agents; Antipsychotic Agents; Behavior, Animal; Body Temperature; Chlo

1964
Peripheral and central effects of atropine and chlorpromazine on gastric motility and ulceration in stressed rats.
    Journal of pharmacobio-dynamics, 1981, Volume: 4, Issue:5

    Topics: Animals; Atropine; Chlorpromazine; Gastrointestinal Motility; Injections, Intravenous; Injections, I

1981
Effect of chlorpromazine on ulcer formation by indomethacin in histamine- and insulin-stimulated rats.
    Physiological research, 1991, Volume: 40, Issue:5

    Topics: Animals; Anti-Ulcer Agents; Chlorpromazine; Gastric Acid; Gastric Mucosa; Histamine; Indomethacin; I

1991
Adverse interaction between cimetidine and chlorpromazine in two cases of chronic schizophrenia.
    The British journal of psychiatry : the journal of mental science, 1989, Volume: 155

    Topics: Chlorpromazine; Cimetidine; Drug Interactions; Esophagitis, Peptic; Female; Humans; Male; Middle Age

1989
[Action of substances protective against ulcers due to constraint in rats maintained at ambiant temperature of 14 degrees C].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1967, Volume: 161, Issue:12

    Topics: Amphetamine; Animals; Atropine; Barbiturates; Bis-Trimethylammonium Compounds; Chlorpromazine; Dextr

1967
[Clinical and experimental studies on the effect of neuroplegic drugs on gastric secretion and peptic ulcers].
    Folia medica Cracoviensia, 1974, Volume: 16, Issue:4

    Topics: Adolescent; Adult; Animals; Cats; Chlorpromazine; Depression, Chemical; Duodenal Ulcer; Female; Gast

1974
[Pharmacologic-endocrinological findings in animal experiments with TURISYNCHRON and SUISYNCHROM. 2. Toxicologic findings].
    Archiv fur experimentelle Veterinarmedizin, 1974, Volume: 28, Issue:5

    Topics: Acute Disease; Administration, Oral; Animals; Atropine; Body Weight; Chlorpromazine; Chronic Disease

1974
Effect of psychotropic drugs on catecholamines in brain and adrenal medulla of rats under stress producing peptic ulcers.
    Japanese journal of pharmacology, 1972, Volume: 22, Issue:4

    Topics: Adrenal Medulla; Animals; Brain Chemistry; Catecholamines; Chlorpromazine; Denervation; Dopamine; Im

1972
General pharmacological properties of 4,5-diphenyl-2-bis-(2-hydroxyethyl)-aminoxazol (ditazol).
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:9

    Topics: Amphetamine; Animals; Anti-Inflammatory Agents; Atropine; Blood Pressure; Cats; Chlorpromazine; Etha

1973
[Properties of drugs decreasing gastric acidity in endoradiosound-controlled treatment of peptic ulcer].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1972, Feb-15, Volume: 25, Issue:4

    Topics: Acid-Base Equilibrium; Adolescent; Adult; Chlorpromazine; Female; Gastric Acidity Determination; Hum

1972
Effects of drugs, ileal obstruction, and irradiation on rat gastrointestinal propulsion.
    Gastroenterology, 1970, Volume: 59, Issue:5

    Topics: Animals; Chlorisondamine; Chlorpromazine; Chromium Isotopes; Fasting; Gastrointestinal Motility; Ile

1970
Indomethacin-induced intestinal lesions in the rat.
    Toxicology and applied pharmacology, 1970, Volume: 17, Issue:3

    Topics: Administration, Oral; Animals; Antacids; Aspirin; Atropine; Bile Ducts; Bretylium Compounds; Chlorpr

1970
[Effect of chlorpromazine on the glucose tolerance test after triamcinolone administration].
    Casopis lekaru ceskych, 1971, Jun-11, Volume: 110, Issue:24

    Topics: Adolescent; Adult; Blood Glucose; Chlorpromazine; Female; Glucose Tolerance Test; Humans; Male; Meth

1971
[Influence of pyschotropic substances on variations of total plasma free fatty acids in constrained rats].
    Archives des sciences physiologiques, 1969, Volume: 23, Issue:3

    Topics: Animals; Chlorpromazine; Depression, Chemical; Dextromoramide; Fatty Acids, Nonesterified; Female; H

1969