chlorpromazine has been researched along with Galactorrhea in 27 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Galactorrhea: Excessive or inappropriate LACTATION in females or males, and not necessarily related to PREGNANCY. Galactorrhea can occur either unilaterally or bilaterally, and be profuse or sparse. Its most common cause is HYPERPROLACTINEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hyperprolactinemia is a common side effect of antipsychotic drugs that requires further investigation." | 5.42 | Chlorpromazine-Induced Hyperprolactinemia on Rat's Uterus. ( Ahmadi, A; Movahed, E; Sadrkhanlou, R; Zamani, Z; Zare, S, 2015) |
| "TRH, metoclopramide (MCP), chlorpromazine (CPZ), and insulin (ITT) stimulation tests of PRL secretion were carried out in age-matched controls and before and after successful removal of pituitary prolactinomas in women with the galactorrhea-amenorrhea syndrome." | 3.66 | Persistent defect in regulation of prolactin secretion after successful pituitary tumor removal in women with the galactorrhea-amenorrhea syndrome. ( Blackard, WG; Gardner, DF; Lankford, HV; Tucker, HS, 1980) |
| "Treatment with sulpiride or chlorpromazine resulted in a significant reduction of psychotic morbidity as estimated by CPRS and global ratings." | 2.65 | Clinical evaluation of sulpiride in schizophrenic patients--a double-blind comparison with chlorpromazine. ( Aberg-Wistedt, A; Bjerkenstedt, L; Björk, K; Gullberg, B; Härnryd, C; Oxenstierna, G; Sedvall, G; Wiesel, FA; Wik, G, 1984) |
| "Pyridoxine has been reported as having an antilactogenic effect, presumably by suppressing prolactin secretion." | 2.64 | Failure of pyridoxine to suppress raised serum prolactin levels. ( de Waal, JM; Harms, JH; Pannall, PR; Slabber, CF; Steyn, AF, 1978) |
| "Hyperprolactinemia is a common side effect of antipsychotic drugs that requires further investigation." | 1.42 | Chlorpromazine-Induced Hyperprolactinemia on Rat's Uterus. ( Ahmadi, A; Movahed, E; Sadrkhanlou, R; Zamani, Z; Zare, S, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (96.30) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (3.70) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zamani, Z | 1 |
| Zare, S | 1 |
| Sadrkhanlou, R | 1 |
| Ahmadi, A | 1 |
| Movahed, E | 1 |
| WINNIK, HZ | 1 |
| TENNENBAUM, L | 1 |
| GAULHOFER, WK | 1 |
| SCHAANK, JR | 1 |
| VALI, A | 1 |
| COLMEIRO-LAFORET, K | 1 |
| TACHEZY, R | 2 |
| VINAROVA, M | 1 |
| KLEIN, JJ | 1 |
| SEGAL, RL | 1 |
| WARNER, RR | 1 |
| MORETTI, O | 1 |
| Board, JA | 1 |
| Fierro, RJ | 1 |
| Härnryd, C | 1 |
| Bjerkenstedt, L | 1 |
| Björk, K | 1 |
| Gullberg, B | 1 |
| Oxenstierna, G | 1 |
| Sedvall, G | 1 |
| Wiesel, FA | 1 |
| Wik, G | 1 |
| Aberg-Wistedt, A | 1 |
| Futterweit, W | 1 |
| Smith, H | 1 |
| Holt, JE | 1 |
| Tucker, HS | 2 |
| Lankford, HV | 2 |
| Gardner, DF | 1 |
| Blackard, WG | 2 |
| Grubb, SR | 1 |
| Wigand, JP | 1 |
| Taylon, A | 1 |
| Becker, DP | 1 |
| Kidd, GS | 1 |
| Dimond, R | 1 |
| Kark, JA | 1 |
| Whorton, N | 1 |
| Vigersky, RA | 1 |
| Hagen, TC | 1 |
| Sill, AJ | 1 |
| Garthwaite, TL | 1 |
| Halverson, G | 1 |
| Borkowf, HI | 1 |
| Johnson, JM | 1 |
| Donald, RA | 1 |
| Espiner, EA | 1 |
| Hodgkinson, SC | 1 |
| Evans, K | 1 |
| Portioli, I | 1 |
| Modena, G | 1 |
| Fantesini, C | 1 |
| Ansari, AH | 1 |
| Pearson, OH | 1 |
| Ayalon, D | 1 |
| Persitz, E | 1 |
| Ravid, R | 1 |
| Jedwab, G | 1 |
| Avidan, S | 1 |
| Cordova, T | 1 |
| Harell, A | 1 |
| Wilson, RG | 1 |
| Hamilton, JR | 1 |
| Boyd, WD | 1 |
| Forrest, AP | 1 |
| Cole, EN | 1 |
| Boyns, AR | 1 |
| Griffiths, K | 1 |
| Boyd, AE | 1 |
| Reichlin, S | 1 |
| Turksoy, RN | 1 |
| de Waal, JM | 1 |
| Steyn, AF | 1 |
| Harms, JH | 1 |
| Slabber, CF | 1 |
| Pannall, PR | 1 |
| Schaison, G | 1 |
| Nathan, C | 1 |
| L'Hermite, M | 1 |
| Kato, Y | 1 |
| Schermann, J | 1 |
| Malarkey, WB | 1 |
1 review available for chlorpromazine and Galactorrhea
| Article | Year |
|---|---|
[Determination of serum prolactin].
Topics: 5-Hydroxytryptophan; Amenorrhea; Brain Diseases; Chlorpromazine; Female; Galactorrhea; Humans; Hypot | 1976 |
2 trials available for chlorpromazine and Galactorrhea
| Article | Year |
|---|---|
Clinical evaluation of sulpiride in schizophrenic patients--a double-blind comparison with chlorpromazine.
Topics: Adolescent; Adult; Benzodiazepines; Chlorpromazine; Clinical Trials as Topic; Double-Blind Method; D | 1984 |
Failure of pyridoxine to suppress raised serum prolactin levels.
Topics: Chlorpromazine; Female; Galactorrhea; Humans; Lactation; Metabolic Diseases; Pregnancy; Prolactin; P | 1978 |
24 other studies available for chlorpromazine and Galactorrhea
| Article | Year |
|---|---|
Chlorpromazine-Induced Hyperprolactinemia on Rat's Uterus.
Topics: Animals; Antipsychotic Agents; Chlorpromazine; Estradiol; Female; Follicle Stimulating Hormone; Gala | 2015 |
[Appearance of galactorrhea during largactil therapy].
Topics: Amenorrhea; Chlorpromazine; Female; Galactorrhea; Humans; Lactation Disorders; Pregnancy | 1955 |
[Galactorrhea due to chlorpromazine].
Topics: Amenorrhea; Chlorpromazine; Female; Galactorrhea; Humans; Lactation Disorders; Pregnancy | 1957 |
[Galactorrhea in chlorpromazine therapy].
Topics: Amenorrhea; Breast Diseases; Chlorpromazine; Female; Galactorrhea; Humans; Lactation Disorders; Preg | 1957 |
[Galactorrhea in psychiatric therapy].
Topics: Amenorrhea; Chlorpromazine; Female; Galactorrhea; Humans; Lactation Disorders; Pregnancy | 1962 |
[Galactorrhea in a male induced by ovarian hormone and chlorpromazine].
Topics: Amenorrhea; Chlorpromazine; Female; Galactorrhea; Humans; Lactation Disorders; Male; Medical Records | 1962 |
GALACTORRHEA DUE TO IMIPRAMINE. REPORT OF A CASE.
Topics: Amenorrhea; Chlorpromazine; Depression; Depressive Disorder; Female; Galactorrhea; Humans; Hypothyro | 1964 |
[Chlorpromazine and appearance of galactorrhea].
Topics: Amenorrhea; Chlorpromazine; Female; Galactorrhea; Humans; Lactation Disorders; Pregnancy | 1960 |
Effect of cyproheptadine on chlorpromazine stimulation of prolactin in women.
Topics: Chlorpromazine; Cyproheptadine; Female; Galactorrhea; Humans; Pregnancy; Prolactin; Prolactin Releas | 1981 |
Dissociation of serum prolactin response to sequential thyrotropin-releasing hormone and chlorpromazine stimulation in patients with primary empty sella syndrome.
Topics: Adult; Chlorpromazine; Empty Sella Syndrome; Female; Galactorrhea; Humans; Hypothalamus; Middle Aged | 1984 |
Persistent defect in regulation of prolactin secretion after successful pituitary tumor removal in women with the galactorrhea-amenorrhea syndrome.
Topics: Amenorrhea; Chlorpromazine; Female; Galactorrhea; Humans; Insulin; Lactation Disorders; Metocloprami | 1980 |
Galactorrhea-amenorrhea syndrome: follow-up of forty-five patients after pituitary tumor removal.
Topics: Adenoma; Adult; Amenorrhea; Chlorpromazine; Female; Follow-Up Studies; Galactorrhea; Humans; Lactati | 1981 |
The effects of pyridoxine on pituitary hormone secretion in amenorrhea-galactorrhea syndromes.
Topics: Adult; Amenorrhea; Chlorpromazine; Female; Galactorrhea; Humans; Lactation Disorders; Levodopa; Pitu | 1982 |
Prolactin and growth hormone responses in the amenorrhea-galactorrhea syndrome.
Topics: Amenorrhea; Chlorpromazine; Female; Galactorrhea; Growth Hormone; Humans; Lactation Disorders; Levod | 1980 |
Treated mania exacerbated by bromocriptine.
Topics: Adult; Affective Disorders, Psychotic; Bipolar Disorder; Bromocriptine; Chlorpromazine; Female; Gala | 1981 |
Measurement of pituitary hormones: clinical applications. 5. Prolactin.
Topics: Acromegaly; Adolescent; Adult; Antipsychotic Agents; Bromocriptine; Chlorpromazine; Craniopharyngiom | 1976 |
[Hyperprolactinemia. Physiopathology and clinical aspects].
Topics: Chlorpromazine; Dysmenorrhea; Erectile Dysfunction; Female; Galactorrhea; Gynecomastia; Humans; Infe | 1978 |
Recent advances in diagnosis and management of galactorrhea.
Topics: Adult; Chlorpromazine; Clomiphene; Female; Galactorrhea; Humans; Lactation Disorders; Levodopa; Pitu | 1978 |
The diagnostic value of pharmacodynamic tests in the hyperprolactinaemic syndrome.
Topics: Adult; Bromocriptine; Chlorpromazine; Female; Follicular Phase; Galactorrhea; Humans; Levodopa; Pitu | 1979 |
The effect of long term phenothiazine therapy on plasma prolactin.
Topics: Aged; Antipsychotic Agents; Breast; Breast Neoplasms; Chlorpromazine; Female; Galactorrhea; Growth H | 1975 |
Galactorrhea-amenorrhea syndrome: diagnosis and therapy.
Topics: Adenoma; Adult; Amenorrhea; Chlorpromazine; Contraceptives, Oral, Synthetic; Estradiol; Female; Foll | 1977 |
[ Study of prolactin and blood gonadotropins in amenorrheas-galactorrhea. Dynamic exploation in 13 cases].
Topics: Adenoma; Adult; Amenorrhea; Chlorpromazine; Dihydroxyphenylalanine; Female; Follicle Stimulating Hor | 1975 |
[Abnormal galactorrhea and the amenorrhea-galactorrhea syndrome].
Topics: Amenorrhea; Chiari-Frommel Syndrome; Chlorpromazine; Female; Galactorrhea; Humans; Hypothyroidism; I | 1976 |
Nonpuerperal lactation and normal prolactin regulation.
Topics: Adult; Amenorrhea; Chlorpromazine; Circadian Rhythm; Estrogens; Female; Follicle Stimulating Hormone | 1975 |