chlorpromazine has been researched along with Eye Disorders in 65 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Melanosis observed in association with prolonged chlorpromazine therapy has become a serious problem in mental institutions." | 7.64 | THERAPY OF CHLORPROMAZINE MELANOSIS: A PRELIMINARY REPORT. ( BAKER, RA; GREINER, AC; NICOLSON, GA, 1964) |
| "Melanosis observed in association with prolonged chlorpromazine therapy has become a serious problem in mental institutions." | 3.64 | THERAPY OF CHLORPROMAZINE MELANOSIS: A PRELIMINARY REPORT. ( BAKER, RA; GREINER, AC; NICOLSON, GA, 1964) |
| "Numerous systemic drugs produce adverse effects that involve the eye." | 2.38 | Ocular side effects of selected systemic drugs. ( Jaanus, SD, 1992) |
| "Chlorpromazine is known to cause ocular pigmentary deposits." | 1.43 | A Case Report: Anti-Psychotic Agents Related Ocular Toxicity. ( Choy, BNK; Fan, MCY; Lai, JSM; Ng, ALK; Shum, JWH, 2016) |
| "A 57-year-old schizoaffective disorder patient was placed on chlorpromazine because of its sedative properties and low profile for extrapyramidal side effects." | 1.29 | Cutaneous and ocular changes associated with the use of chlorpromazine. ( Berk, MA; Mosnaim, AD; Richer, S; Wolf, ME, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 60 (92.31) | 18.7374 |
| 1990's | 3 (4.62) | 18.2507 |
| 2000's | 1 (1.54) | 29.6817 |
| 2010's | 1 (1.54) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Choy, BNK | 1 |
| Ng, ALK | 1 |
| Shum, JWH | 1 |
| Fan, MCY | 1 |
| Lai, JSM | 1 |
| BIERENT, P | 1 |
| LEVY, JP | 1 |
| GRAMBERG-DANIELSEN, B | 2 |
| FREY, B | 1 |
| MAUREL, H | 1 |
| SPIELMANN, JP | 1 |
| BAUMANN, H | 1 |
| WISTRAND, P | 1 |
| WAITZMAN, MB | 1 |
| BOCK, R | 1 |
| SWAIN, J | 1 |
| GREINER, AC | 2 |
| NICOLSON, GA | 2 |
| BAKER, RA | 1 |
| MASSEY, LW | 1 |
| CAIRNS, RJ | 1 |
| CAPOORE, HS | 1 |
| GREGORY, ID | 1 |
| TREDICI, LM | 1 |
| SCHIELE, BC | 1 |
| MCCLANAHAN, WS | 1 |
| WETTERHOLM, DH | 1 |
| SNOW, HL | 3 |
| WINTER, FC | 1 |
| BARSA, JA | 1 |
| NEWTON, JC | 1 |
| SAUNDERS, JC | 1 |
| Imaizumi, M | 1 |
| Ikebe, T | 1 |
| Ikewaki, J | 1 |
| Nakatsuka, K | 1 |
| Gombos, GM | 1 |
| Yarden, PE | 1 |
| Cameron, ME | 2 |
| Deluise, VP | 1 |
| Flynn, JT | 1 |
| Wolf, ME | 1 |
| Richer, S | 1 |
| Berk, MA | 1 |
| Mosnaim, AD | 1 |
| Gol'dovskaia, IL | 3 |
| Crews, SJ | 1 |
| Klíma, M | 1 |
| Klímová, A | 1 |
| Lisch, K | 1 |
| Jaanus, SD | 1 |
| Brooks, JG | 1 |
| Matoba, AY | 1 |
| Thaler, JS | 1 |
| Curinga, R | 1 |
| Kiracofe, G | 1 |
| Axelrod, FB | 1 |
| Nachtigal, R | 1 |
| Dancis, J | 1 |
| Francesconi, G | 1 |
| Di Tizio, A | 1 |
| Cameo, D | 1 |
| Pouliquen, Y | 1 |
| Graf, B | 1 |
| Bisson, J | 1 |
| Feuvrier, YM | 1 |
| Delattre, A | 1 |
| Barg, TsM | 1 |
| Verrey, F | 1 |
| Cuendet, JF | 2 |
| Nouri, A | 2 |
| Kleberger, E | 1 |
| Siddall, JR | 2 |
| De Long, SL | 1 |
| Marzulli, FN | 1 |
| Bernstein, HN | 1 |
| Goldman, D | 1 |
| Petrohelos, MA | 2 |
| Tricoulis, D | 2 |
| Kalberer, M | 1 |
| Atar, Z | 1 |
| Bider, E | 1 |
| Barron, CN | 2 |
| Rubin, LF | 2 |
| Steelman, RL | 2 |
| Davidorf, FH | 1 |
| Edler, K | 1 |
| Gottfries, CG | 1 |
| Haslund, J | 1 |
| Ravn, J | 1 |
| Mathalone, MB | 2 |
| Johnson, AW | 1 |
| Henkes, HE | 1 |
| Boet, DJ | 1 |
| Prien, RF | 1 |
| DeLong, SL | 1 |
| Cole, JO | 1 |
| Levine, J | 1 |
| Ellis, PP | 1 |
| Macri, F | 1 |
| Forrest, FM | 2 |
| Brückner, R | 1 |
| Sandvig, K | 1 |
| Valentine, M | 1 |
| Jardine, P | 1 |
| Barnes, GJ | 1 |
| Sarin, LK | 1 |
| Leopold, IH | 1 |
| Winkelman, NW | 1 |
| Erickson, G | 1 |
| Geiter, CW | 1 |
| Laxson, GO | 1 |
10 reviews available for chlorpromazine and Eye Disorders
| Article | Year |
|---|---|
[Drug-induced visual disturbance].
Topics: Amiodarone; Anti-Asthmatic Agents; Antimalarials; Antitubercular Agents; Antiviral Agents; Chloroqui | 2007 |
[Psychotropic therapy and intraocular pressure].
Topics: Amitriptyline; Analgesics; Antidepressive Agents; Chlorpromazine; Diazepam; Diphenhydramine; Eye Dis | 1975 |
Ocular side effects of selected systemic drugs.
Topics: Amiodarone; Anti-Inflammatory Agents; Antirheumatic Agents; Chloroquine; Chlorpromazine; Drug Intera | 1992 |
Familial dysautonomia: diagnosis, pathogenesis and management.
Topics: Adolescent; Adult; Anesthesia; Bethanechol Compounds; Body Temperature Regulation; Child; Child, Pre | 1974 |
[Eye complications during use of various medicinal substances with general effects (review of the literature)].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Allopurinol; Anti-Bacterial Agents; Antimalari | 1969 |
[Damage to eyes through conservative therapy].
Topics: Accommodation, Ocular; Animals; Chlorpromazine; Chymotrypsin; Conjunctiva; Conjunctivitis; Cornea; D | 1967 |
Ocular complications related to phenothiazines.
Topics: Chlorpromazine; Eye Diseases; Eyelids; Female; Humans; Male; Mydriatics; Phenothiazines; Pigmentatio | 1968 |
Ocular side effects of drugs.
Topics: Animals; Cataract; Chlorpromazine; Dogs; Drug-Related Side Effects and Adverse Reactions; Electroret | 1968 |
[Complications on the part of the eyes during employment of psychotropic drugs (review of the foreign literature)].
Topics: Chlorpromazine; Corneal Opacity; Eye Diseases; Female; Humans; Lens, Crystalline; Male; Methotrimepr | 1969 |
Some iatrogenic ocular diseases from systemically administered drugs.
Topics: Animals; Cataract; Cats; Chemical Phenomena; Chemistry; Chloramphenicol; Chloroquine; Chlorpromazine | 1970 |
2 trials available for chlorpromazine and Eye Disorders
| Article | Year |
|---|---|
Incidence and significance of chlorpromazine-induced eye changes.
Topics: Chlorpromazine; Clinical Trials as Topic; Cornea; Eye Diseases; Female; Granuloma; Humans; Lens, Cry | 1968 |
Ocular changes occurring with prolonged high dose chlorpromazine therapy. Results from a collaborative study.
Topics: Adult; Chlorpromazine; Cornea; Eye Diseases; Female; Humans; Lens, Crystalline; Male; Middle Aged; S | 1970 |
53 other studies available for chlorpromazine and Eye Disorders
| Article | Year |
|---|---|
A Case Report: Anti-Psychotic Agents Related Ocular Toxicity.
Topics: Aged; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Eye Diseases; Female; Humans; Olanzapin | 2016 |
Chlorpromazine (45.60 R. P.) in ophthalmology: preliminary note.
Topics: Chlorpromazine; Eye Diseases; Humans; Ophthalmology | 1954 |
[Largactil in retrobulbar injection].
Topics: Chlorpromazine; Eye Diseases; Glaucoma; Humans; Injections | 1955 |
[Megaphen in ophthalmology].
Topics: Chlorpromazine; Eye Diseases; Humans; Ophthalmology | 1956 |
[Megaphen in ophthalmology].
Topics: Chlorpromazine; Eye Diseases; Humans; Ophthalmology | 1956 |
[Megaphen in ophthalmology].
Topics: Chlorpromazine; Eye Diseases; Humans; Ophthalmology | 1956 |
[Megaphen in ophthalmology].
Topics: Chlorpromazine; Eye Diseases; Humans; Ophthalmology | 1956 |
[Oculogyric crises during successive treatment with reserpine & chlorpromazine].
Topics: Chlorpromazine; Disease; Dystonic Disorders; Eye Diseases; Eye Movements; Humans; Muscles; Oculomoto | 1957 |
[The problem of injuries to the organ of vision caused by protracted & high-dosed largactil therapy; appendix; largactil medication in ophthalmology].
Topics: Appendix; Chlorpromazine; Dental Care; Eye Diseases; Humans; Ophthalmology | 1957 |
The failure of promethazine and chlorpromazine to prevent the eye-pressure response to local irritation of the iris.
Topics: Chlorpromazine; Eye Diseases; Humans; Intraocular Pressure; Iris; Promethazine; Tonometry, Ocular | 1958 |
Influences of chlorpromazine on aqueous humor dynamics.
Topics: Aqueous Humor; Chlorpromazine; Eye Diseases; Intraocular Pressure; Tonometry, Ocular | 1963 |
OPHTHALMOLOGIC FINDINGS IN PATIENTS ON LONG-TERM CHLORPROMAZINE THERAPY.
Topics: Chlorpromazine; Eye Diseases; Glaucoma; Intraocular Pressure; Ophthalmology; Photosensitivity Disord | 1963 |
PIGMENT DEPOSITION IN VISCERA ASSOCIATED WITH PROLONGED CHLORPROMAZINE THERAPY.
Topics: Adolescent; Autonomic Nervous System; Cerebral Cortex; Chlorpromazine; Cornea; Endocrine Glands; Epi | 1964 |
THERAPY OF CHLORPROMAZINE MELANOSIS: A PRELIMINARY REPORT.
Topics: Body Fluids; Chlorpromazine; Copper; Darkness; Drug Therapy; Eye Diseases; Histocytochemistry; Hospi | 1964 |
SKIN PIGMENTATION, CORNEAL AND LENS OPACITIES WITH PROLONGED CHLORPROMAZINE TREATMENT.
Topics: Biopsy; Cataract; Chlorpromazine; Cornea; Corneal Opacity; Drug Therapy; Electrocardiography; Eye Di | 1965 |
OCULOCUTANEOUS CHANGES AFTER YEARS OF HIGH DOSES OF CHLORPROMAZINE.
Topics: Chlorpromazine; Diagnosis; Drug Eruptions; Eye Diseases; Facial Dermatoses; Pathology; Pigmentation | 1965 |
THE INCIDENCE AND MANAGEMENT OF CHLORPROMAZINE--SKIN-EYE SYNDROME.
Topics: Chlorpromazine; Drug Therapy; Eye Diseases; Incidence; Minnesota; Pigmentation Disorders; Syndrome; | 1965 |
A CLINICAL STUDY OF PIGMENTARY CHANGE IN CORNEA AND LENS IN CHRONIC CHLORPROMAZINE THERAPY.
Topics: Amblyopia; Chlorpromazine; Cornea; Drug Therapy; Eye Diseases; Humans; Lens, Crystalline; Mental Dis | 1965 |
LENS AND CORENEA CHANGES DURING PHENOTHIAZINE THERAPY: A PRELIMINARY REPORT.
Topics: Chlorpromazine; Corneal Opacity; Drug Therapy; Eye Diseases; Fluphenazine; Lens, Crystalline; Mental | 1965 |
Ocular and cutaneous side effects after prolonged chlorpromazine treatment.
Topics: Chlorpromazine; Corneal Opacity; Eye Diseases; Humans; Israel; Lens, Crystalline; Male; Schizophreni | 1967 |
Ocular melanosis with special reference to chlorpromazine.
Topics: Chlorpromazine; Conjunctiva; Cornea; Eye Diseases; Eyelids; Female; Humans; Lens, Crystalline; Male; | 1967 |
Asymmetric anterior segment changes induced by chlorpromazine.
Topics: Blepharoptosis; Cataract; Chlorpromazine; Conjunctival Diseases; Corneal Opacity; Eye Diseases; Huma | 1981 |
Cutaneous and ocular changes associated with the use of chlorpromazine.
Topics: Carcinoma, Basal Cell; Chlorpromazine; Drug Eruptions; Eye Diseases; Humans; Male; Middle Aged; Mout | 1993 |
Ocular adverse reactions to drugs.
Topics: Adrenal Cortex Hormones; Adult; Aged; Amblyopia; Cataract; Chloroquine; Chlorpromazine; Conjunctivit | 1977 |
[Ocular complications in long-term chlorpromazine treatment].
Topics: Adult; Aged; Chlorpromazine; Eye Diseases; Female; Humans; Male; Middle Aged | 1977 |
[Ophthalmic-pharmacological complications (author's transl)].
Topics: Atropine; Chlorpromazine; Corneal Diseases; Eye Diseases; Humans; Male; Middle Aged; Mydriatics; Phe | 1976 |
Chlorpromazine-induced anterior segment changes.
Topics: Aged; Anterior Eye Segment; Chlorpromazine; Eye Diseases; Humans; Male; Schizophrenia; Visual Acuity | 1992 |
Relation of graded ocular anterior chamber pigmentation to phenothiazine intake in schizophrenics--quantification procedures.
Topics: Anterior Chamber; Chlorpromazine; Cornea; Eye Diseases; Humans; Pigmentation Disorders; Schizophreni | 1985 |
[Ocular and cutaneous changes in patients exposed to prolonged treatment with neuroleptic drugs].
Topics: Adult; Aged; Chlorpromazine; Conjunctiva; Cornea; Drug Eruptions; Eye Diseases; Female; Humans; Lens | 1968 |
[Ultrastructural study of corneal thickening in the course of chlorpromazine treatment].
Topics: Biopsy; Chlorpromazine; Cornea; Epithelium; Eye Diseases; Female; Humans; Melanins; Membranes; Micro | 1970 |
[Study of the aqueous humor after prolonged treatment with neuroleptics].
Topics: Aqueous Humor; Cataract; Chlorpromazine; Cornea; Eye Diseases; Humans; Time Factors | 1972 |
Prolonged treatment of psychotic states. (Over 1600 patients treated continuously 3 to 7 years).
Topics: Antidepressive Agents; Chlorpromazine; Chronic Disease; Eye Diseases; Female; Humans; Long-Term Care | 1968 |
[Ocular involvement during prolonged treatment with neuroleptics].
Topics: Adult; Aged; Chlorpromazine; Corneal Opacity; Eye Diseases; Female; Fundus Oculi; Humans; Lens, Crys | 1968 |
Ocular complications of chlorpromazine therapy.
Topics: Adolescent; Adult; Aged; Chlorpromazine; Cornea; Eye Diseases; Female; Glaucoma; Humans; Lens, Cryst | 1969 |
Ocular complications of chlorpromazine therapy.
Topics: Adolescent; Adult; Aged; Chlorpromazine; Eye Diseases; Female; Greece; Humans; Long-Term Care; Male; | 1969 |
[Ocular changes in long-term treatment with Largactil].
Topics: Adult; Aged; Chlorpromazine; Color Perception; Dark Adaptation; Electrooculography; Electroretinogra | 1970 |
Chlorpromazine and the eye of the dog. IV. Reversibility of ocular lesions.
Topics: Animals; Chlorpromazine; Cornea; Cytoplasmic Granules; Dogs; Eye Diseases; Female; Humans; Male; Pen | 1972 |
Chlorpromazine and the eye of the dog. V. Attempt to produce lenticular lesions.
Topics: Administration, Oral; Animals; Chlorpromazine; Cornea; Cytoplasmic Granules; Depression; Dogs; Eye D | 1972 |
Ocular toxicity of systemic drugs. A review of the effects of seven commonly used agents.
Topics: Chloramphenicol; Chloroquine; Chlorpromazine; Contraceptives, Oral; Eye Diseases; Glucocorticoids; H | 1972 |
Eye changes in connection with neuroleptic treatment especially concerning phenothiazines and thioxanthenes.
Topics: Adult; Age Factors; Aged; Cataract; Chlorpromazine; Cornea; Evaluation Studies as Topic; Eye Disease | 1971 |
Ocular complications of phenothiazines.
Topics: Adult; Chlorpromazine; Conjunctiva; Cornea; Eye Diseases; Female; Fundus Oculi; Humans; Intraocular | 1966 |
Chlorpromazine ocular toxicity.
Topics: Chlorpromazine; Eye Diseases; Humans | 1967 |
Electro-oculography as a diagnostic aid in phenothiazin retinopathy.
Topics: Adult; Chlorpromazine; Electrooculography; Eye Diseases; Female; Humans; Male; Mental Disorders; Mid | 1967 |
[Ophthalmologic study of patients receiving psychotropic drugs].
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents; Bipolar Disorder; Cataract; Cerebrova | 1970 |
Toxic effects of phenothiazines on the eye.
Topics: Adult; Arsenic; Cataract; Chemical Phenomena; Chemistry; Chlorpromazine; Color Vision Defects; Conju | 1970 |
Ocular complications of systemic medications.
Topics: Adrenal Cortex Hormones; Chloroquine; Chlorpromazine; Eye Diseases; Humans | 1971 |
Chlorpromazine.
Topics: Animals; Chlorpromazine; Eye; Eye Diseases; Humans | 1971 |
Phenothiazines in ophthalmology.
Topics: Cataract; Chlorpromazine; Chorioretinitis; Eye Diseases; Humans; Melanins; Microscopy; Phenothiazine | 1967 |
Prognosis of eye complications caused by phenothiazines.
Topics: Black People; Chlorpromazine; Cornea; Diagnosis, Differential; Eye Diseases; Female; Humans; Lens, C | 1968 |
Ocular effects of phenothiazine derivatives and reversibility.
Topics: Accommodation, Ocular; Animals; Cats; Chlorpromazine; Cornea; Eye Diseases; Female; Fundus Oculi; Hu | 1968 |
[Early diagnosis of drug damage to the retina and optic nerve].
Topics: Adult; Aged; Anti-Bacterial Agents; Anticoagulants; Antimalarials; Chlorpromazine; Contraceptives, O | 1969 |
Corneal and lens changes after prolonged treatment with chlorpromazine.
Topics: Adolescent; Adult; Aged; Chlorpromazine; Cornea; Eye Diseases; Female; Humans; Lens, Crystalline; Ma | 1965 |
Phenothiazines and eye complications.
Topics: Adult; Chlorpromazine; Eye Diseases; Female; Humans; Male; Middle Aged; Schizophrenia; Tranquilizing | 1966 |
Skin and eye changes associated with chlorpromazine therapy.
Topics: Chlorpromazine; Epilepsy; Eye Diseases; Female; Humans; Male; Mental Disorders; Pigmentation Disorde | 1966 |
Ocular examinations in outpatients given long-term chlorpromazine therapy.
Topics: Adult; Aged; Chlorpromazine; Chronic Disease; Eye Diseases; Female; Follow-Up Studies; Humans; Male; | 1966 |
Incidence of late "melanosis" side effects in chronic mental patients after long term phenothiazine therapy.
Topics: Chlorpromazine; Eye Diseases; Fluphenazine; Humans; Male; Melanosis; Penicillamine; Perphenazine; Th | 1966 |