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chlorpromazine and Experimental Radiation Injuries

chlorpromazine has been researched along with Experimental Radiation Injuries in 17 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Research Excerpts

ExcerptRelevanceReference
"The present study was performed to assess the effects of pilocarpine hydrochloride ((3S,4R)-3-ethyl-dihydro-4-[(1-methyl-1H-imidazole-5-yl)methyl]-2(3H)-furanone monohydrochloride, CAS 54-71-7) and cevimeline ((+/-)-cis-2-methylspiro[1,3-oxathiolane-5,3'-quinuclidine] hydrochloride, hemihydrate, CAS 153504-70-2), muscarinic receptor agonists, on salivary secretion from the submandibular/sublingual (SM/SL) glands in normal rats and in rats with xerostomia induced by X-ray (15 Gy) irradiation."7.72Effects of pilocarpine hydrochloride and cevimeline on submandibular/sublingual salivation in rat xerostomia model produced by X-ray irradiation. ( Asari, T; Kojima, M; Kusama, H; Maruyama, K; Omori, Y; Shibata, N, 2003)
"The present study was performed to assess the effects of pilocarpine hydrochloride ((3S,4R)-3-ethyl-dihydro-4-[(1-methyl-1H-imidazole-5-yl)methyl]-2(3H)-furanone monohydrochloride, CAS 54-71-7) and cevimeline ((+/-)-cis-2-methylspiro[1,3-oxathiolane-5,3'-quinuclidine] hydrochloride, hemihydrate, CAS 153504-70-2), muscarinic receptor agonists, on salivary secretion from the submandibular/sublingual (SM/SL) glands in normal rats and in rats with xerostomia induced by X-ray (15 Gy) irradiation."3.72Effects of pilocarpine hydrochloride and cevimeline on submandibular/sublingual salivation in rat xerostomia model produced by X-ray irradiation. ( Asari, T; Kojima, M; Kusama, H; Maruyama, K; Omori, Y; Shibata, N, 2003)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199016 (94.12)18.7374
1990's0 (0.00)18.2507
2000's1 (5.88)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Omori, Y1
Asari, T1
Maruyama, K1
Kusama, H1
Kojima, M1
Shibata, N1
DIMITROV, L1
RUPKEY, AK1
GOLD, R1
RUGH, R1
WANG, SC1
ARBUZOV, SI1
MIKHEEVA, EG1
ANDRIANOVA, LA1
McDonald, CJ1
Snell, RS1
Lerner, AB1
Gralla, EJ1
Sabo, JP1
Hayden, DW1
Yochmowitz, MG1
Mattsson, JL1
Půlpánová, J2
Ledvina, M2
Koldaev, VM1
Stern, WK1
Prokhorova, MI1
Zakharova, LI1
Norman, TN1
Osadchaia, LM1
Siniutina, NF1
Zellmer, R1
Culver, J1
Pickering, JE1
Dilley, JV1
McDonald, KE1
Varshamov, IuL2
Ushakov, BN1
Stetiukha, NM1

Reviews

1 review available for chlorpromazine and Experimental Radiation Injuries

ArticleYear
[Use of chemical substances in ultrahigh frequency electromagnetic radiation (review of the literature)].
    Farmakologiia i toksikologiia, 1972, Volume: 35, Issue:4

    Topics: Animals; Anura; Ascorbic Acid; Atropine; Chlorpromazine; Epinephrine; Ergotamine; Glucose; Humans; M

1972

Other Studies

16 other studies available for chlorpromazine and Experimental Radiation Injuries

ArticleYear
Effects of pilocarpine hydrochloride and cevimeline on submandibular/sublingual salivation in rat xerostomia model produced by X-ray irradiation.
    Arzneimittel-Forschung, 2003, Volume: 53, Issue:5

    Topics: Animals; Antipsychotic Agents; Body Temperature; Cardiovascular System; Central Nervous System; Chlo

2003
The effect of alcohol and largactil on the resistance of the organism to ionizing irradiation.
    Comptes rendus de l'Academie Bulgare des sciences : sciences mathematiques et naturelles, 1962, Volume: 15

    Topics: Animals; Biochemical Phenomena; Chlorpromazine; Ethanol; Hypothermia; Hypothermia, Induced; Radiatio

1962
Effects of drugs alone, or combined with refrigeration, in protecting female mice against x-irradiation-induced sterility.
    Radiation research, 1963, Volume: 19

    Topics: Animals; Chlorpromazine; Dihydroergotoxine; Ergot Alkaloids; Female; Infertility; Infertility, Femal

1963
[ROLE OF THE CENTRAL NERVOUS SYSTEM IN RESTORATIVE AND COMPENSATORY PROCESSES FOLLOWING THE ACTION OF RADIATION-PROTECTIVE AGENTS].
    Sbornik vedeckych praci Lekarske fakulty Karlovy university v Hradci Kralove, 1963, Volume: 6

    Topics: Animals; Central Nervous System; Central Nervous System Stimulants; Cerebral Cortex; Chlorpromazine;

1963
[EFFECT OF EXPERIMENTAL ROENTGEN IRRADIATION ON INTRAOCULAR PRESSURE AND PERMEABILITY OF OCULAR VESSELS].
    Oftalmologicheskii zhurnal, 1964, Volume: 19

    Topics: Animals; Bis-Trimethylammonium Compounds; Chlorpromazine; Intraocular Pressure; Permeability; Pharma

1964
[THE EFFECT OF IONIZING RADIATIONS ON THE NEUROSECRETION OF THE HYPOTHALAMIC NUCLEI].
    Biulleten' eksperimental'noi biologii i meditsiny, 1965, Volume: 59

    Topics: Animals; Brain; Chlorpromazine; Hypothalamus; Neurosecretion; Pharmacology; Rabbits; Radiation Injur

1965
The effect of chlorpromazine on oculocutaneous pigmentation in the guinea pig.
    The Journal of investigative dermatology, 1967, Volume: 49, Issue:1

    Topics: Animals; Chlorpromazine; Corneal Opacity; Eye; Guinea Pigs; Pigmentation; Radiation Injuries, Experi

1967
The effect of selected drugs on first-stage radioemesis in beagle dogs.
    Radiation research, 1979, Volume: 78, Issue:2

    Topics: Amifostine; Amphetamine; Animals; Antiemetics; Body Weight; Chlorpromazine; Dimenhydrinate; Diphenhy

1979
[The excretion of chlorpromazin metabolic products in irradiated rats (author's transl)].
    Radiobiologia, radiotherapia, 1978, Volume: 19, Issue:4

    Topics: Animals; Biotransformation; Chlorpromazine; Male; Radiation Injuries, Experimental; Rats

1978
[The effect of ionizing radiation on the excretion of chlorpromazine metabolites in rats].
    Radiobiologia, radiotherapia, 1978, Volume: 19, Issue:4

    Topics: Animals; Biotransformation; Chlorpromazine; Male; Radiation Injuries, Experimental; Rats

1978
Anatomic localization of the response to ultraviolet radiation in human skin.
    Dermatologica, 1972, Volume: 145, Issue:6

    Topics: Animals; Biopsy; Chlorpromazine; Dose-Response Relationship, Radiation; Erythema; Humans; Light; Pho

1972
[Effect of aminazin on metabolism of brain amino acids and gangliosides].
    Voprosy biokhimii mozga, 1972, Volume: 7, Issue:0

    Topics: Amino Acids; Animals; Aspartic Acid; Brain; Chlorpromazine; Galactosamine; Gangliosides; Glutamates;

1972
Proton-irradiation effects in primates.
    Radiation research. Supplement, 1967, Volume: 7

    Topics: Alpha Particles; Animals; Chlorpromazine; Haplorhini; Protons; Radiation Injuries, Experimental; Rad

1967
Removal of inhaled 239PuO2 in rats. BNWL-714.
    BNWL [reports]. U.S. Atomic Energy Commission, 1968

    Topics: Aerosols; Animals; Chlorpromazine; Gels; Lung; Plutonium; Progesterone; Radiation Injuries, Experime

1968
[Mechanism of the genesis of emesis in the period of the primary reaction to irradiation].
    Meditsinskaia radiologiia, 1966, Volume: 11, Issue:1

    Topics: Animals; Apomorphine; Chlorpromazine; Copper; Dogs; Radiation Injuries, Experimental; Sulfates; Vagu

1966
[The use of aminazine and phenamine in primary reaction to irradiation].
    Meditsinskaia radiologiia, 1966, Volume: 11, Issue:11

    Topics: Amphetamine; Animals; Chlorpromazine; Dogs; Humans; Male; Radiation Injuries; Radiation Injuries, Ex

1966