chlorpromazine has been researched along with Experimental Neoplasms in 53 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chlorpromazine (CPZ) distribution was measured in tissues of Syrian golden hamsters bearing Greene melanoma and in BALB/c mice bearing Harding-Passey melanoma." | 7.66 | Chlorpromazine distribution in hamsters and mice bearing transplantable melanoma. ( Atkins, HL; Brill, AB; Fairchild, RG; Fand, I; Greenberg, D; Hannon, SJ; McNally, WP; Packer, S; Som, P; Watts, KP, 1982) |
| "Chlorpromazine (CPZ) distribution was measured in tissues of Syrian golden hamsters bearing Greene melanoma and in BALB/c mice bearing Harding-Passey melanoma." | 3.66 | Chlorpromazine distribution in hamsters and mice bearing transplantable melanoma. ( Atkins, HL; Brill, AB; Fairchild, RG; Fand, I; Greenberg, D; Hannon, SJ; McNally, WP; Packer, S; Som, P; Watts, KP, 1982) |
| "The therapeutic usefulness of chlorpromazine (CPZ) and caffeine (CAF) in combination with selected nitrosoureas was investigated in mice bearing L1210 leukemia, Lewis lung carcinoma, and B16 melanoma." | 3.66 | Therapeutic potentiation of nitrosoureas using chlorpromazine and caffeine in the treatment of murine tumors. ( Dykes, DJ; Laster, WR; Rose, WC; Schabel, FM; Trader, MW, 1978) |
| "Centrophenoxine, without antitumor activity itself, enhanced the cytotoxic action of melphalan and "activated" cyclophosphamide against mouse P388 lymphoma and rat W256 carcinosarcoma cells growing in static suspension culture." | 3.65 | Potentiation of the cytotoxic action of melphalan and "activated" cyclophosphamide against cultured tumor cells by centrophenoxine. ( Sladek, NE, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 49 (92.45) | 18.7374 |
| 1990's | 4 (7.55) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| PETERS, K | 2 |
| GARTNER, H | 1 |
| KRAIS, W | 1 |
| BELKIN, M | 2 |
| HARDY, WG | 2 |
| ANDREJEW, A | 1 |
| ROSENBERG, AJ | 2 |
| SZAFARZ, D | 1 |
| WYSSMANN, L | 1 |
| DOMENJOZ, R | 1 |
| SCHELLENBERG, H | 3 |
| OLSZEWSKI, A | 1 |
| HOWARD, JM | 1 |
| STRAWITZ, JG | 1 |
| BACIGALUPO, G | 1 |
| POTTS, AM | 1 |
| CARLINI, GR | 1 |
| FISCHER, GA | 1 |
| GIARMAN, NJ | 1 |
| DAY, M | 1 |
| STOCKBRIDGE, A | 1 |
| LACASSAGNE, A | 1 |
| MOSINGER, M | 1 |
| SAVINSKAIA, AP | 1 |
| Vorona, AP | 2 |
| Shenoy, MA | 1 |
| Biaglow, JE | 1 |
| Varnes, ME | 1 |
| Hetzel, FW | 1 |
| Syrkin, AB | 1 |
| Voronia, TA | 1 |
| Mikhaĭlova, LM | 1 |
| Suslov, NI | 1 |
| Nakanishi, T | 1 |
| Ichihashi, M | 1 |
| Mishima, Y | 2 |
| Matsuzawa, T | 1 |
| Fukuda, H | 1 |
| George, KC | 1 |
| Srinivasan, VT | 1 |
| Singh, BB | 1 |
| Fairchild, RG | 1 |
| Greenberg, D | 1 |
| Watts, KP | 1 |
| Packer, S | 1 |
| Atkins, HL | 1 |
| Som, P | 1 |
| Hannon, SJ | 1 |
| Brill, AB | 1 |
| Fand, I | 1 |
| McNally, WP | 1 |
| Heindel, JJ | 1 |
| Clement-Cormier, YC | 1 |
| Ishikawa, M | 1 |
| Takayanagi, Y | 1 |
| Sasaki, K | 1 |
| Loncar-Stevanović, H | 1 |
| Vujović, Z | 1 |
| Drazić, A | 1 |
| Lazić, D | 1 |
| Jakulić, S | 1 |
| Jovanović, T | 1 |
| Kudriashov, BA | 1 |
| Kolomina, SM | 1 |
| Chentsov, IuS | 1 |
| Kalishevskaia, TM | 1 |
| Pogodina, LS | 1 |
| Sladek, NE | 1 |
| Rose, WC | 1 |
| Trader, MW | 1 |
| Dykes, DJ | 1 |
| Laster, WR | 1 |
| Schabel, FM | 1 |
| Balanski, RM | 1 |
| Dzhioev, FK | 1 |
| Fingar, VH | 1 |
| Wieman, TJ | 1 |
| Park, YJ | 1 |
| Henderson, BW | 1 |
| Hultborn, R | 1 |
| Lundgren-Eriksson, L | 1 |
| Ottosson-Lönn, S | 1 |
| Ryd, W | 1 |
| Weiss, L | 1 |
| Lazo, JS | 1 |
| Chen, DL | 1 |
| Gallicchio, VS | 1 |
| Hait, WN | 1 |
| Lehnert, S | 1 |
| Jones, GR | 1 |
| Mückter, H | 1 |
| Moré, E | 1 |
| Zbytniewski, Z | 1 |
| Drewa, G | 1 |
| Hilz, H | 1 |
| Jarmers, G | 1 |
| Homburger, F | 1 |
| Dybing, E | 1 |
| Jamieson, D | 1 |
| Van den Brenk, HA | 1 |
| Pradhan, SN | 1 |
| Ray, P | 1 |
| Voĭtkevich, ND | 1 |
| Palyga, GF | 1 |
| Polliack, A | 2 |
| Levij, IS | 2 |
| Sviatukhin, MV | 1 |
| Kovaleva, VL | 1 |
| Rees, KR | 1 |
| Rowland, GF | 1 |
| Varcoe, JS | 1 |
| Van Woert, MH | 3 |
| Palmer, SH | 1 |
| Saunders, RN | 1 |
| Miya, TS | 1 |
| Bousquet, WF | 1 |
| Burnett, JB | 1 |
| Korb, F | 1 |
| Prasad, KN | 1 |
| Cooper, M | 1 |
2 reviews available for chlorpromazine and Experimental Neoplasms
| Article | Year |
|---|---|
Cancer therapy: phenothiazines in an unexpected role.
Topics: Animals; Chlorpromazine; Hospitals, Psychiatric; Humans; Neoplasms; Neoplasms, Experimental; Oxidati | 1985 |
[Antiradiation effect of mexamine].
Topics: 5-Methoxytryptamine; Animals; beta-Aminoethyl Isothiourea; Blood Coagulation; Bone Marrow; Bone Marr | 1974 |
51 other studies available for chlorpromazine and Experimental Neoplasms
| Article | Year |
|---|---|
[Separate and combined effects of radium and megaphen on ascitic tumor in mice].
Topics: Animals; Chlorpromazine; Mice; Neoplasms; Neoplasms, Experimental; Radium | 1955 |
[Cytological and toxicological studies on the influence of megaphen on colchicine effects].
Topics: Animals; Chlorpromazine; Colchicine; Leadership; Neoplasms, Experimental | 1955 |
Effect of reserpine and chlorpromazine on sarcoma 37.
Topics: Animals; Chlorpromazine; Neoplasms, Experimental; Reserpine; Sarcoma 37; Sarcoma, Experimental | 1957 |
Effect of reserpine and chlorpromazine on sarcoma 37.
Topics: Animals; Chlorpromazine; Neoplasms, Experimental; Reserpine; Sarcoma 37; Sarcoma, Experimental | 1957 |
Effect of reserpine and chlorpromazine on sarcoma 37.
Topics: Animals; Chlorpromazine; Neoplasms, Experimental; Reserpine; Sarcoma 37; Sarcoma, Experimental | 1957 |
Effect of reserpine and chlorpromazine on sarcoma 37.
Topics: Animals; Chlorpromazine; Neoplasms, Experimental; Reserpine; Sarcoma 37; Sarcoma, Experimental | 1957 |
[Effect of chlorpromazine on the development of an ascitic hepatoma in the rat in vivo].
Topics: Animals; Carcinoma, Hepatocellular; Chlorpromazine; Liver Neoplasms; Liver Neoplasms, Experimental; | 1957 |
[Effect of chlorpromazine on metabolic activity of nucleic acids in tumor cells & their mitochondria].
Topics: Animals; Chlorpromazine; Humans; Mitochondria; Neoplasms, Experimental; Nucleic Acids | 1959 |
[Pharmacological studies on 5-hydroxytryptamine metabolism in mastocytoma].
Topics: Chlorpromazine; Dihydroxyphenylalanine; Imipramine; Iproniazid; Isocarboxazid; Mastocytoma; Mastocyt | 1962 |
THE USE OF SEROTONIN, CHLORPROMAZINE AND OTHER AGENTS FOR CONDITIONING HOSTS FOR TUMOR HETEROTRANSPLANTATION.
Topics: Chlorpromazine; Cortisone; Neoplasms; Neoplasms, Experimental; Phenoxybenzamine; Radiation Effects; | 1963 |
UNCOUPLING THE OXIDATIVE PHOSPHORYLATION IN THE COMBINED CHEMOTHERAPY OF CANCER.
Topics: Adenosine Triphosphate; Antimetabolites; Antineoplastic Agents; Carcinoma 256, Walker; Chlorpromazin | 1964 |
TRACER STUDIES ON A TRANSPLANTABLE HAMSTER MELANOMA.
Topics: Animals; Chlorpromazine; Cricetinae; Eye Neoplasms; Fluoresceins; Idoxuridine; Iodine Isotopes; Mela | 1964 |
DIFFERENCES IN CHARACTERISTICS OF RELEASE OF SEROTONIN FROM NEOPLASTIC MAST CELLS IN CULTURE BY RESERPINE AND CHLORPROMAZINE.
Topics: Chlorpromazine; Mast Cells; Metabolism; Monoamine Oxidase Inhibitors; Neoplasms; Neoplasms, Experime | 1964 |
THE EFFECTS OF DRUGS ON THE UPTAKE OF AMINES BY MAST CELLS.
Topics: Amines; Animals; Chlorpromazine; Cocaine; Ethanolamines; Guanethidine; Hallucinogens; Histamine; Imi | 1964 |
[RELATIONS BETWEEN THE TUMOR AND ORGANISM. THE ROLE OF THE HYPOTHALAMUS].
Topics: Chlorpromazine; Gold; Hypothalamus; Neoplasms; Neoplasms, Experimental; Neurophysiology; Pharmacolog | 1964 |
[Treatment of sarcoma in rats with castor oil, ganglion blocking agents, and somatotropin; general and peritumoral mastocytosis].
Topics: Animals; Castor Oil; Chlorpromazine; Growth Hormone; Mast Cells; Mastocytosis; Neoplasms, Experiment | 1955 |
[Effect of aminazin and iprazide on the appearance and development of induced tumors in rats].
Topics: Animals; Chlorpromazine; Iproniazid; Neoplasms; Neoplasms, Experimental; Rats | 1962 |
[Effect of chlorpromazine and imipramine on cultures of some malignant and normal tissue].
Topics: Animals; Chlorpromazine; Imipramine; Immunologic Tests; Neoplasms, Experimental; Research Design; Ti | 1961 |
[Effect of chlorpromazine and imipramine on the respiration and anaerobic glycolysis of mastocytoma P-815 and Ehrlich ascites tumor].
Topics: Animals; Carbohydrate Metabolism; Carbohydrates; Carcinoma, Ehrlich Tumor; Chlorpromazine; Glycolysi | 1961 |
[On the effect of aminazine on the induction and growth of tumors].
Topics: Animals; Benz(a)Anthracenes; Chlorpromazine; Female; Neoplasm Transplantation; Neoplasms, Experiment | 1966 |
Inhibition of cultured human tumor cell oxygen utilization by chlorpromazine.
Topics: Aerobiosis; Anaerobiosis; Animals; Carcinoma, Ehrlich Tumor; Cells, Cultured; Chlorpromazine; Cricet | 1983 |
[Pharmacological compatibility of the antineoplastic drugs ftorafur and 5-fluorouracil with the psychotropic drugs aminazine and phenazepam (an experimental study)].
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Chlorpromazine; Drug Interactions; | 1984 |
Thermal neutron capture therapy of malignant melanoma: in vitro radiobiological analysis.
Topics: Alpha Particles; Animals; Boron; Cell Line; Cell Survival; Chlorpromazine; Dose-Response Relationshi | 1980 |
Cytotoxic effect of chlorpromazine and its interaction with radiation on a mouse fibrosarcoma.
Topics: Animals; Cell Survival; Chlorpromazine; Fibrosarcoma; Mice; Neoplasms, Experimental; Oxygen; Radiati | 1980 |
Chlorpromazine distribution in hamsters and mice bearing transplantable melanoma.
Topics: Animals; Autoradiography; Chlorpromazine; Cricetinae; Drug Administration Schedule; Injections, Intr | 1982 |
Regulation of adenylate cyclase activity in GH1 cells by chlorpromazine and a heat-stable factor.
Topics: Adenylyl Cyclases; Animals; Calcium; Cell Line; Chelating Agents; Chlorpromazine; Enzyme Activation; | 1981 |
Drug interaction effects on antitumor drugs. XIII. Amelioration of cisplatin lethality and renal toxicity by chlorpromazine in mice.
Topics: Animals; Blood Urea Nitrogen; Chlorpromazine; Cisplatin; Drug Interactions; Glycosuria; Kidney; L-La | 1993 |
The influence of selenium and neuroleptics on the rat brain nuclear regulatory mechanism in carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antipsychotic Agents; Brain; Car | 1998 |
[Effect of substances that increase the activity of the anti-coagulating system of tumor-bearing animals on the growth of metastases and on the ultrastructure of the metastatic cells].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blood Coagulation; Carcinoma 256, Walker; Chlorpromazine; | 1977 |
Potentiation of the cytotoxic action of melphalan and "activated" cyclophosphamide against cultured tumor cells by centrophenoxine.
Topics: Animals; Antineoplastic Agents; Carcinoma 256, Walker; Cell Division; Cells, Cultured; Chlorpromazin | 1977 |
Therapeutic potentiation of nitrosoureas using chlorpromazine and caffeine in the treatment of murine tumors.
Topics: Animals; Caffeine; Carmustine; Chlorpromazine; Drug Synergism; Drug Therapy, Combination; Female; Le | 1978 |
[The relationship between the activity of microsomal enzymes and pulmonary carcinogenesis in mice].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Antineoplastic Agents; Barbital; Chlorpromazine; | 1976 |
Implications of a pre-existing tumor hypoxic fraction on photodynamic therapy.
Topics: Animals; Cell Hypoxia; Chlorpromazine; Dihematoporphyrin Ether; Epinephrine; Female; Fluorescein; Fl | 1992 |
Chlorpromazine-induced hypothermia in tumour-bearing mice, acute cytotoxic drug lethality and long-term survival.
Topics: Animals; Chlorpromazine; Doxorubicin; Hypothermia, Induced; Mice; Mice, Inbred C57BL; Neoplasms, Exp | 1990 |
Increased lethality of calmodulin antagonists and bleomycin to human bone marrow and bleomycin-resistant malignant cells.
Topics: Bleomycin; Bone Marrow; Bone Marrow Cells; Calmodulin; Cell Survival; Chlorpromazine; Dose-Response | 1986 |
In vivo toxicity of phenothiazines to cells of a transplantable tumor.
Topics: Animals; Antipsychotic Agents; Cell Survival; Chlorpromazine; Male; Mice; Mice, Inbred C3H; Neoplasm | 1986 |
[Thalidomide and cancer].
Topics: Animals; Antineoplastic Agents; Benz(a)Anthracenes; Chlormadinone Acetate; Chlorpromazine; Cyclophos | 1966 |
Inhibition of growth of transplantable melanotic melanoma in golden hamsters (Mesocricetus auratus, Waterhouse) by chlorpromazine.
Topics: Acid Phosphatase; Animals; Catechol Oxidase; Cathepsins; Chlorpromazine; Cricetinae; Liver; Male; Me | 1973 |
[Stimulation of tumor growths by anesthesia].
Topics: Adrenalectomy; Anesthesia; Anesthetics; Animals; Carcinogens; Carcinoma, Ehrlich Tumor; Cell Differe | 1967 |
Chemical carcinogenesis in Syrian hamsters.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Animals; Azo Compounds; Benz(a)Anthracenes; Benzopyrenes; Bronc | 1972 |
Inhibitory effects of chlorpromazine and diethylaminoethyl diphenylvalerate (SKF 525-A) on alanine incorporation into protein and -aminoisobutyric acid uptake in rat hepatoma cells in culture.
Topics: Alanine; Aminobutyrates; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cells, Cultured; Chlor | 1973 |
Studies of mechanisms of chemical radiation protection in vivo. 3. Changes in fluorescence of intracellular pyridine nucleotides and modification by extracellular hypoxia.
Topics: Animals; Antidotes; beta-Aminoethyl Isothiourea; Chlorpromazine; Cystamine; Dimethyl Sulfoxide; Extr | 1966 |
Effects of stress on growth of transplanted and 7,12-dimethylbenz(alpha)anthracene-induced tumors and their modification by psychotropic drugs.
Topics: Adrenal Glands; Animals; Benz(a)Anthracenes; Body Weight; Chlorpromazine; Electroshock; Female; Huma | 1974 |
Antineoplastic effect of chlorpromazine in chemical carcinogenesis in the hamster cheek pouch.
Topics: Animals; Antineoplastic Agents; Benz(a)Anthracenes; Carcinoma; Carcinoma, Squamous Cell; Cheek; Chlo | 1972 |
[Effect of aminazin on the growth of transplantable melanomas and on the effect of their x-ray irradiation].
Topics: Animals; Chlorpromazine; Injections, Intraperitoneal; Melanoma; Mice; Neoplasm Transplantation; Neop | 1973 |
Studies on the binding of tritiated rho-dimethylaminoazobenzene in rat liver and the role of intranuclear binding sites in the early stages of carcinogenesis.
Topics: Animals; Carcinogens; Chlorpromazine; Hexobarbital; Liver; Liver Neoplasms; Male; Neoplasms, Experim | 1965 |
Inhibition of the growth of mouse melanoma by chlorpromazine.
Topics: Animals; Antineoplastic Agents; Body Weight; Catechol Oxidase; Chlorpromazine; Melanoma; Mice; Neopl | 1969 |
Stimulation of DOPA14C incorporation into melanoma tissue by chlorpromazine and reserpine.
Topics: Animals; Carbon Isotopes; Catechol Oxidase; Chlorpromazine; Dihydroxyphenylalanine; In Vitro Techniq | 1970 |
Effect of phenothiazines on melanoma tyrosinase activity.
Topics: Adrenal Glands; Animals; Basidiomycota; Carbon Isotopes; Catechol Oxidase; Cell Membrane Permeabilit | 1970 |
The tyrosinases of mouse melanoma. Isolation and molecular properties.
Topics: Acrylates; Alcohols; Amino Acids; Animals; Catechol Oxidase; Chemical Phenomena; Chemistry; Chlorpro | 1971 |
Regulation of tyrosinase activity in mouse melanoma and skin by changes in melanosomal membrane permeability.
Topics: Animals; Bile Acids and Salts; Catechol Oxidase; Cell Membrane Permeability; Chloroquine; Chlorproma | 1971 |
Increased in vitro radio-sensitivity of malignant melanoma induced by the in vivo administration of chlorpromazine.
Topics: Animals; Chlorpromazine; Cricetinae; Free Radicals; Melanins; Melanoma; Neoplasm Transplantation; Ne | 1972 |
Inhibition of chemical carcinogenesis in the hamster cheek pouch by topical chlorpromazine.
Topics: Animals; Benz(a)Anthracenes; Chlorpromazine; Cricetinae; Disease Models, Animal; Mouth Mucosa; Neopl | 1970 |
[The status of the thyroid gland and thyrotropic function of the hypophysis in rats with induced tumors during administration of aminazin].
Topics: Animals; Benz(a)Anthracenes; Chlorpromazine; Iodine Isotopes; Male; Neoplasms, Experimental; Pituita | 1968 |