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chlorpromazine and Escherichia coli Infections

chlorpromazine has been researched along with Escherichia coli Infections in 17 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Escherichia coli Infections: Infections with bacteria of the species ESCHERICHIA COLI.

Research Excerpts

ExcerptRelevanceReference
"The effect of chlorpromazine (CPZ) on diarrhea caused by enterotoxigenic Escherichia coli was tested in piglets since CPZ has been shown to be a potent antagonist to enterotoxins in vitro in a cell system and in vivo in a mouse model."7.66Chlorpromazine reverses diarrhea in piglets caused by enterotoxigenic Escherichia coli. ( Andrén, B; Holmgren, J; Lange, S; Lönnroth, I; Martinsson, K, 1979)
"The inhibitory effect of chlorpromazine (CPZ), pentoxifylline (PTX) and dexamethasone (DEX) was investigated in a model of endotoxin shock in Holstein calves following an intravenous administration of Esherichia coli endotoxin (LPS)."3.69Inhibitory effect on LPS-induced tumor necrosis factor in calves treated with chlorpromazine or pentoxifylline. ( Higuchi, T; Matsuzawa, H; Ohtsuka, H; Sato, H; Takahashi, J; Takahashi, K; Yoshino, TO, 1997)
"Effects of chlorpromazine and propranolol were tested in infant mice model of Enterotoxigenic Escherichia coli diarrhea."3.66Chlorpromazine and propranolol extend survival of infant mice inoculated with enterotoxigenic Escherichia coli. ( Bertin, A, 1981)
"The effect of chlorpromazine (CPZ) on diarrhea caused by enterotoxigenic Escherichia coli was tested in piglets since CPZ has been shown to be a potent antagonist to enterotoxins in vitro in a cell system and in vivo in a mouse model."3.66Chlorpromazine reverses diarrhea in piglets caused by enterotoxigenic Escherichia coli. ( Andrén, B; Holmgren, J; Lange, S; Lönnroth, I; Martinsson, K, 1979)
" Chlorpromazine, administered intramuscularly on 3 successive days following the dual infection in 8 K88ac susceptible pigs, in a dosage of 2 and 1."1.28Effect of chlorpromazine on experimental diarrhoea in just-weaned piglets. ( Cools, V; Cox, E; Houvenaghel, A, 1989)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199013 (76.47)18.7374
1990's1 (5.88)18.2507
2000's2 (11.76)29.6817
2010's1 (5.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Malyukova, I1
Murray, KF1
Zhu, C1
Boedeker, E1
Kane, A1
Patterson, K1
Peterson, JR1
Donowitz, M1
Kovbasnjuk, O1
Chanteloup, NK1
Porcheron, G1
Delaleu, B1
Germon, P1
Schouler, C1
Moulin-Schouleur, M1
Gilot, P1
WEIL, MH1
ALLEN, KS1
DAVYDOV, VP1
Black, RE1
Bertin, A1
Ohtsuka, H1
Higuchi, T1
Matsuzawa, H1
Sato, H1
Takahashi, K1
Takahashi, J1
Yoshino, TO1
Clancy, KD1
Lorenz, K1
Dries, D1
Gamelli, RL1
Hahn, EL1
Lönnroth, I1
Andrén, B1
Lange, S1
Martinsson, K1
Holmgren, J1
Cox, E2
Cools, V2
Houvenaghel, A2
Weikel, CS1
Guerrant, RL1
Willard, MD1
Meyer, W2
Popenenkova, ZA1
Romanovskaia, MG1
Bailey, GL1
Strub, RL1

Reviews

3 reviews available for chlorpromazine and Escherichia coli Infections

ArticleYear
The prophylaxis and therapy of secretory diarrhea.
    The Medical clinics of North America, 1982, Volume: 66, Issue:3

    Topics: Anti-Infective Agents, Urinary; Antidiarrheals; Chloramphenicol; Chlorpromazine; Cholera; Diarrhea;

1982
[Cliniccal aspects, pathogenesis and therapy of shock due to sepsis caused by gram-negative organisms].
    Schweizerische medizinische Wochenschrift, 1966, Feb-05, Volume: 96, Issue:5

    Topics: Adult; Animals; Blood; Chlorpromazine; Diarrhea; Dogs; Electrocardiography; Endotoxins; Escherichia

1966
[Clinical aspects, pathogenesis and therapy of shock due to sepsis caused by gram-negative organisms].
    Schweizerische medizinische Wochenschrift, 1966, Feb-05, Volume: 96, Issue:5

    Topics: Adult; Aldosterone; Animals; Blood; Chlorpromazine; Diarrhea; Dogs; Electrocardiography; Endotoxins;

1966

Other Studies

14 other studies available for chlorpromazine and Escherichia coli Infections

ArticleYear
Macropinocytosis in Shiga toxin 1 uptake by human intestinal epithelial cells and transcellular transcytosis.
    American journal of physiology. Gastrointestinal and liver physiology, 2009, Volume: 296, Issue:1

    Topics: Actins; Animals; cdc42 GTP-Binding Protein; Cell Line; Cell Membrane; Chlorpromazine; Clathrin; Dise

2009
The extra-intestinal avian pathogenic Escherichia coli strain BEN2908 invades avian and human epithelial cells and survives intracellularly.
    Veterinary microbiology, 2011, Jan-27, Volume: 147, Issue:3-4

    Topics: Alveolar Epithelial Cells; Animals; Anti-Bacterial Agents; Birds; Cell Line; Chlorpromazine; Cytocha

2011
COMPARISON OF SYMPATHETIC BLOCKING DRUGS IN PREVENTION OF LETHAL EFFECTS OF ENDOTOXIN.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1964, Volume: 115

    Topics: Chlorpromazine; Endotoxins; Escherichia coli Infections; Mice; Pharmacology; Phenoxybenzamine; Phent

1964
[THERAPY OF COLI INFECTIONS IN INFANTS].
    Voprosy okhrany materinstva i detstva, 1964, Volume: 9

    Topics: Child; Chlorpromazine; Coliphages; Escherichia coli Infections; Gastroenteritis; Humans; Infant; Pro

1964
Chlorpromazine and propranolol extend survival of infant mice inoculated with enterotoxigenic Escherichia coli.
    Annales de recherches veterinaires. Annals of veterinary research, 1981, Volume: 12, Issue:2

    Topics: Administration, Oral; Animals; Chlorpromazine; Diarrhea; Escherichia coli Infections; Injections, Su

1981
Inhibitory effect on LPS-induced tumor necrosis factor in calves treated with chlorpromazine or pentoxifylline.
    The Journal of veterinary medical science, 1997, Volume: 59, Issue:11

    Topics: Animals; Cattle; Chlorpromazine; Dexamethasone; Endotoxins; Escherichia coli Infections; Female; Lip

1997
Chlorpromazine modulates cytokine expression in the liver and lung after burn injury and endotoxemia.
    The Journal of trauma, 2000, Volume: 48, Issue:2

    Topics: Animals; Burns; Chemokine CCL4; Chlorpromazine; Endotoxemia; Escherichia coli Infections; Interleuki

2000
Chlorpromazine reverses diarrhea in piglets caused by enterotoxigenic Escherichia coli.
    Infection and immunity, 1979, Volume: 24, Issue:3

    Topics: Adenylyl Cyclases; Animals; Chlorpromazine; Diarrhea; Enterotoxins; Escherichia coli Infections; Int

1979
Effect of chlorpromazine on experimental diarrhoea in just-weaned piglets.
    Zentralblatt fur Veterinarmedizin. Reihe A, 1989, Volume: 36, Issue:2

    Topics: Animals; Chlorpromazine; Diarrhea; Disease Models, Animal; Escherichia coli Infections; Female; Gast

1989
Effect of antisecretory drugs on experimentally induced weanling diarrhoea in piglets.
    Veterinary research communications, 1989, Volume: 13, Issue:2

    Topics: Animals; Animals, Newborn; Chlorpromazine; Clonidine; Diarrhea; Disease Models, Animal; Escherichia

1989
STb enterotoxin of Escherichia coli: cyclic nucleotide-independent secretion.
    Ciba Foundation symposium, 1985, Volume: 112

    Topics: Animals; Bacterial Toxins; Calcium; Chlorides; Chlorpromazine; Cyclic AMP; Diarrhea; Electrolytes; E

1985
Newer concepts in treatment of secretory diarrheas.
    Journal of the American Veterinary Medical Association, 1985, Jan-01, Volume: 186, Issue:1

    Topics: Animals; Antidiarrheals; Chlorpromazine; Diarrhea; Enterotoxins; Escherichia coli Infections; Fluid

1985
[The effect of vetrazine, chlorazicin and eminazine on bacterial infection].
    Zhurnal mikrobiologii, epidemiologii i immunobiologii, 1969, Volume: 46, Issue:9

    Topics: Animals; Chlorpromazine; Escherichia coli; Escherichia coli Infections; Hydrazines; Monoamine Oxidas

1969
Gram-negative septic shock: the new approach.
    Southern medical journal, 1966, Volume: 59, Issue:11

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Bicarbonates; Blood Pressure Determination; Chlorpromazine

1966