chlorpromazine has been researched along with Epilepsy, Temporal Lobe in 13 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Epilepsy, Temporal Lobe: A localization-related (focal) form of epilepsy characterized by recurrent seizures that arise from foci within the TEMPORAL LOBE, most commonly from its mesial aspect. A wide variety of psychic phenomena may be associated, including illusions, hallucinations, dyscognitive states, and affective experiences. The majority of complex partial seizures (see EPILEPSY, COMPLEX PARTIAL) originate from the temporal lobes. Temporal lobe seizures may be classified by etiology as cryptogenic, familial, or symptomatic. (From Adams et al., Principles of Neurology, 6th ed, p321).
| Excerpt | Relevance | Reference |
|---|---|---|
| "QUIN seizures showed particular sensitivity to carbamazepine (5 mg/kg) but were resistant to diphenylhydantoin unless a relatively high dose was used (100 mg/kg)." | 5.27 | Anticonvulsant drugs effective against human temporal lobe epilepsy prevent seizures but not neurotoxicity induced in rats by quinolinic acid: electroencephalographic, behavioral and histological assessments. ( Samanin, R; Tullii, M; Vezzani, A; Wu, HQ, 1986) |
| "QUIN seizures showed particular sensitivity to carbamazepine (5 mg/kg) but were resistant to diphenylhydantoin unless a relatively high dose was used (100 mg/kg)." | 1.27 | Anticonvulsant drugs effective against human temporal lobe epilepsy prevent seizures but not neurotoxicity induced in rats by quinolinic acid: electroencephalographic, behavioral and histological assessments. ( Samanin, R; Tullii, M; Vezzani, A; Wu, HQ, 1986) |
| "Twenty-six children with Tourette's syndrome (TS) and 24 with a temporal form of epilepsy were examined." | 1.27 | [Features of the temporal structure of the respiratory cycle in the Tourette syndrome as a possible reflection of intensified dopaminergic processes]. ( Kenunen, OG; Kharitonov, RA; Shchelkunov, EL; Voronov, IB; Zimin, AL, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| FISCHER-WILLIAMS, M | 1 |
| COOPER, RA | 1 |
| KLAPETEK, J | 1 |
| MAYR, F | 1 |
| LECHNER, H | 1 |
| Silberman, EK | 1 |
| Post, RM | 1 |
| Vol'f, MSh | 1 |
| Adebimpe, VR | 1 |
| Vezzani, A | 1 |
| Wu, HQ | 1 |
| Tullii, M | 1 |
| Samanin, R | 1 |
| Shchelkunov, EL | 1 |
| Kenunen, OG | 1 |
| Voronov, IB | 1 |
| Zimin, AL | 1 |
| Kharitonov, RA | 1 |
| Viukari, NM | 1 |
| Wilder, B | 1 |
| Mokrán, V | 1 |
| Cigánek, L | 1 |
| Kabátník, Z | 1 |
| Zlotlow, M | 1 |
| Ignjatović, M | 1 |
| Nastović, I | 1 |
| Khajduković, C | 1 |
| Cujković, M | 1 |
1 trial available for chlorpromazine and Epilepsy, Temporal Lobe
| Article | Year |
|---|---|
Diphenylhydantoin as an anticonvulsant: evaluation of treatment in forty mentally subnormal epileptics.
Topics: Adolescent; Adult; Chlorpromazine; Clinical Trials as Topic; Electroencephalography; Epilepsies, Par | 1969 |
12 other studies available for chlorpromazine and Epilepsy, Temporal Lobe
| Article | Year |
|---|---|
DEPTH RECORDING FROM THE HUMAN BRAIN IN EPILEPSY.
Topics: Adolescent; Amygdala; Astrocytoma; Bemegride; Caudate Nucleus; Child; Chlorpromazine; Electroencepha | 1963 |
[ALTERATION OF LATENT EPILEPTIC ACTIVITY IN THE ELECTROENCEPHALOGRAM WITH CHLORPROMAZINE].
Topics: Chlorpromazine; Electroencephalography; Epilepsy; Epilepsy, Temporal Lobe; Humans; Pharmacology; Tem | 1964 |
[The question of provocation in temporal lobe epilepsy in the EEG].
Topics: Chlorpromazine; Electroencephalography; Epilepsy; Epilepsy, Temporal Lobe; Humans | 1954 |
The march of symptoms in a psychotic decompensation. Case report and theoretical implications.
Topics: Adolescent; Adult; Affective Disorders, Psychotic; Behavior; Carbamazepine; Chlorpromazine; Drug The | 1980 |
[Psychotropic drugs in the clinical picture of epilepsy (review of the literature)].
Topics: Amitriptyline; Animals; Anti-Anxiety Agents; Anticonvulsants; Antipsychotic Agents; Carbamazepine; C | 1975 |
Complex partial seizures simulating schizophrenia .
Topics: Adult; Chlorpromazine; Diagnosis, Differential; Diagnostic Errors; Diazepam; Electroencephalography; | 1977 |
Anticonvulsant drugs effective against human temporal lobe epilepsy prevent seizures but not neurotoxicity induced in rats by quinolinic acid: electroencephalographic, behavioral and histological assessments.
Topics: Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Chlorpromazine; Diazepam; Disease Models, | 1986 |
[Features of the temporal structure of the respiratory cycle in the Tourette syndrome as a possible reflection of intensified dopaminergic processes].
Topics: Adolescent; Brain; Child; Chlorpromazine; Dopamine; Epilepsy, Temporal Lobe; Female; Haloperidol; Hu | 1985 |
Electroencephalogram activation in medically intractable epileptic patients. Activation technique including surgical follow-up.
Topics: Adolescent; Adult; Chlorpromazine; Electroencephalography; Epilepsy, Temporal Lobe; Female; Humans; | 1971 |
Electroencephalographic theta discharges in the midline.
Topics: Adolescent; Adult; Brain; Chlorpromazine; Electroencephalography; Epilepsy, Temporal Lobe; Female; H | 1971 |
Temporal lobe "spike focus" associated with confusion, complete amnesia and fugues in a paranoid schizophrenic.
Topics: Adult; Amnesia; Chlorpromazine; Cognition Disorders; Dissociative Disorders; Electroencephalography; | 1968 |
[Productive psychotic episodes with forces normalization of the electroencephalogram].
Topics: Chlorpromazine; Electroencephalography; Epilepsy, Temporal Lobe; Humans | 1966 |