chlorpromazine has been researched along with Endotoxemia in 2 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Endotoxemia: A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chlorpromazine-treated hypothermic mice had 2." | 1.36 | Hypothermia increases interleukin-6 and interleukin-10 in juvenile endotoxemic mice. ( Fairchild, KD; Gurka, MJ; Landseadel, JP; Stewart, CR, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stewart, CR | 1 |
| Landseadel, JP | 1 |
| Gurka, MJ | 1 |
| Fairchild, KD | 1 |
| Clancy, KD | 1 |
| Lorenz, K | 1 |
| Dries, D | 1 |
| Gamelli, RL | 1 |
| Hahn, EL | 1 |
2 other studies available for chlorpromazine and Endotoxemia
| Article | Year |
|---|---|
Hypothermia increases interleukin-6 and interleukin-10 in juvenile endotoxemic mice.
Topics: Animals; Chlorpromazine; Cytokines; Endotoxemia; Endotoxins; Hyperthermia, Induced; Hypothermia; Int | 2010 |
Chlorpromazine modulates cytokine expression in the liver and lung after burn injury and endotoxemia.
Topics: Animals; Burns; Chemokine CCL4; Chlorpromazine; Endotoxemia; Escherichia coli Infections; Interleuki | 2000 |