chlorpromazine has been researched along with Edema in 46 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chlorpromazine administered to Sprague-Dawley rats 30 minutes prior to burning dramatically minimized burn oedema by a factor of 7 compared with controls." | 7.66 | Acquired local resistance to burns: prevention of its acquisition by chlorpromazine. ( Babyatsky, M; Bibi, RR; Levenson, SM, 1983) |
| "To confirm the inflammatory activity of polymeric photoproducts (CPZ-polymers) of chlorpromazine (CPZ), which were obtained by gel filtration of a UV-pre-irradiated CPZ aqueous solution, the histamine release from rat peritoneal exudate cells was studied and the paw-inflammation in mice induced by these CPZ-polymers was examined." | 3.68 | Inflammatory activity of polymeric photoproducts of chlorpromazine. ( Isobe, A; Kakegawa, H; Matsumoto, H; Miyataka, H; Satoh, T; Shigehara, N, 1993) |
| "Chlorpromazine administered to Sprague-Dawley rats 30 minutes prior to burning dramatically minimized burn oedema by a factor of 7 compared with controls." | 3.66 | Acquired local resistance to burns: prevention of its acquisition by chlorpromazine. ( Babyatsky, M; Bibi, RR; Levenson, SM, 1983) |
| " Buffers to combat acidosis, oxygen to combat hypoxemia, hypertonic Mannitol to mobilize edema." | 3.65 | Treatment of pre-eclampsia and eclampsia as a hypoperfusion syndrome. ( Grenroth, C; Norée, LO; Söder, G; Wiklund, PE, 1975) |
| " Significant inhibition of oedema formation caused by thermal injury was observed for calcium carbaspirin, phenylbutazone, hydrocortisone, cryogenine and indomethacin when given daily beginning 2 days prior to thermal exposure and afterwards." | 3.65 | Evaluation of cryogenine on rat paw thermal oedema and rat isolated uterus. ( Malone, MH; Trottier, RW, 1973) |
| " Pretreatment with CPZ partially protected these organs from the toxic effects of CdCl(2)." | 1.30 | The antagonistic effect of chlorpromazine on cadmium toxicity. ( El-Ashmawy, IM; Youssef, SA, 1999) |
| "Chlorpromazine, which has been used extensively for the treatment of psychiatric disorders, is known to accumulate in the posterior corneal stroma, lens, and uveal tract." | 1.26 | Chlorpromazine-induced corneal endothelial phototoxicity. ( Csukas, S; Green, K; Hull, DS, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 42 (91.30) | 18.7374 |
| 1990's | 3 (6.52) | 18.2507 |
| 2000's | 1 (2.17) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Feitosa, RF | 1 |
| Melcíades, GB | 1 |
| Assreuy, AM | 1 |
| Rocha, MF | 1 |
| Ribeiro, RA | 1 |
| Lima, AA | 1 |
| DECORTIS, A | 1 |
| COURVOISIER, S | 1 |
| DUCROT, R | 1 |
| MILLON, R | 1 |
| GABRIELLE, P | 1 |
| LANDRY, M | 1 |
| MARX, HH | 1 |
| BASALISCO, F | 2 |
| SCHIAPARELLI, P | 2 |
| LACASSIE, R | 2 |
| BULLE, PH | 1 |
| SZABO, G | 1 |
| SOLTI, F | 1 |
| REV, J | 1 |
| MEGYESI, K | 1 |
| FANTIS, A | 1 |
| KRYSPIN, J | 1 |
| METCALF, RG | 1 |
| KUNA, A | 1 |
| MACCARRON, D | 1 |
| HIRSCH, S | 1 |
| LECHTENBERG, HW | 1 |
| LENFELD, J | 1 |
| SLADKOVA, O | 1 |
| GRUNDMAN, M | 1 |
| ARRIGONIMARTELLI, E | 1 |
| CONTI, I | 1 |
| BROWN, DM | 1 |
| ROBSON, RD | 1 |
| SMITH, AN | 1 |
| PRESHAW, RM | 1 |
| SIRCUS, W | 1 |
| HERTTING, G | 1 |
| STOKLASKA, E | 1 |
| Felder, M | 1 |
| Bibi, RR | 1 |
| Babyatsky, M | 1 |
| Levenson, SM | 1 |
| Campbell, DJ | 1 |
| Mendelsohn, FA | 1 |
| Adam, WR | 1 |
| Funder, JW | 1 |
| Hull, DS | 1 |
| Csukas, S | 1 |
| Green, K | 1 |
| Shigehara, N | 1 |
| Kakegawa, H | 1 |
| Miyataka, H | 1 |
| Matsumoto, H | 1 |
| Isobe, A | 1 |
| Satoh, T | 1 |
| Babu, AS | 1 |
| Gowda, TV | 1 |
| El-Ashmawy, IM | 1 |
| Youssef, SA | 1 |
| Petritsch, PH | 1 |
| Meffert, H | 1 |
| el Bashir, MH | 1 |
| Sönnichsen, N | 1 |
| Söder, G | 1 |
| Grenroth, C | 1 |
| Norée, LO | 1 |
| Wiklund, PE | 1 |
| Thomas, G | 1 |
| Sousa, PS | 1 |
| Witz, L | 1 |
| Shapiro, MS | 1 |
| Shenkman, L | 1 |
| Niewenhuis, RJ | 1 |
| Prozialeck, WC | 1 |
| Somogyi, A | 1 |
| Selye, H | 1 |
| Carrano, RA | 1 |
| Malbica, JO | 1 |
| Eger, W | 1 |
| Schulz, E | 1 |
| Geschickter, CF | 1 |
| Aronson, RS | 1 |
| Geschickter, EH | 1 |
| Schulterbrandt, JG | 1 |
| Raskin, A | 1 |
| Reatig, N | 1 |
| Rassaert, CL | 1 |
| Richter, RS | 1 |
| Martin, J | 1 |
| DiPasquale, G | 1 |
| Malone, MH | 4 |
| Trottier, RW | 1 |
| Tsurumi, K | 1 |
| Hayashi, M | 1 |
| Abe, A | 1 |
| Go, K | 1 |
| Fujimura, H | 1 |
| De Cato, L | 1 |
| Brown, JK | 1 |
| Graf, H | 1 |
| Kocialski, AB | 1 |
| Marozzi, FJ | 1 |
| Demers, RG | 1 |
| Hendler, R | 1 |
| Allen, RP | 1 |
| Boyd, J | 1 |
| Jaques, R | 1 |
| Riesterer, L | 1 |
| Chang, YC | 1 |
| Casadio, S | 1 |
| Bruzzese, T | 1 |
| Pala, G | 1 |
| Coppi, G | 1 |
| Turba, C | 1 |
2 reviews available for chlorpromazine and Edema
| Article | Year |
|---|---|
[The fibrositis syndrome (author's transl)].
Topics: Adult; Behavior Therapy; Chlorpromazine; Edema; Endorphins; Female; Fibromyalgia; Humans; Male; Midd | 1980 |
Is aldosterone secretion under dopaminergic control?
Topics: Aldosterone; Bromocriptine; Chlorpromazine; Dopamine; Dopamine Antagonists; Edema; Humans; Levodopa; | 1981 |
1 trial available for chlorpromazine and Edema
| Article | Year |
|---|---|
True and apparent side effects in a controlled trial of chlorpromazine and imipramine in depression.
Topics: Adult; Agranulocytosis; Chlorpromazine; Clinical Trials as Topic; Depression; Dermatitis; Edema; Eva | 1974 |
43 other studies available for chlorpromazine and Edema
| Article | Year |
|---|---|
The pharmacological profile of ovalbumin-induced paw oedema in rats.
Topics: Animals; Anti-Allergic Agents; Azepines; Chlorpromazine; Dopamine Antagonists; Dose-Response Relatio | 2002 |
[Phenothiazine derivatives in febrile coronary angina and acute pulmonary edema].
Topics: Angina Pectoris; Anti-Allergic Agents; Chlorpromazine; Edema; Histamine H1 Antagonists; Lung Disease | 1954 |
[Action of chlorpromazine (R.P. 4560) on the edema syndrome induced by dextran in the rat].
Topics: Animals; Chlorpromazine; Dextrans; Edema; Rats; Syndrome | 1955 |
[Severe pulmonary edema during Sakel cure; efficacy of chlorpromazine].
Topics: Chlorpromazine; Convulsive Therapy; Edema; Female; Humans; Insulin; Lung Diseases; Pre-Eclampsia; Pr | 1956 |
[Depressive effects of phenothiazine].
Topics: Antipsychotic Agents; Chlorpromazine; Edema; Humans; Phenothiazines; Respiration | 1956 |
[Therapy of exudative diathesis in infants].
Topics: Child; Chlorpromazine; Cortisone; Disease Susceptibility; Edema; Humans; Infant; Skin Diseases | 1956 |
[Therapy of exudative diathesis in infants].
Topics: Child; Chlorpromazine; Cortisone; Disease Susceptibility; Edema; Humans; Infant; Skin Diseases | 1956 |
[Therapy of exudative diathesis in infants].
Topics: Child; Chlorpromazine; Cortisone; Disease Susceptibility; Edema; Humans; Infant; Skin Diseases | 1956 |
[Therapy of exudative diathesis in infants].
Topics: Child; Chlorpromazine; Cortisone; Disease Susceptibility; Edema; Humans; Infant; Skin Diseases | 1956 |
[Treatment of acute edema of the lung by chlorpromazine].
Topics: Chlorpromazine; Edema; Humans; Pulmonary Edema | 1956 |
[Treatment of acute edema of the lung by chlorpromazine].
Topics: Chlorpromazine; Edema; Humans; Pulmonary Edema | 1956 |
[Treatment of acute edema of the lung by chlorpromazine].
Topics: Chlorpromazine; Edema; Humans; Pulmonary Edema | 1956 |
[Treatment of acute edema of the lung by chlorpromazine].
Topics: Chlorpromazine; Edema; Humans; Pulmonary Edema | 1956 |
Effects of reserpine and chlorpromazine in prevention of cerebral edema and reversible cell damage.
Topics: Biomedical Research; Brain Edema; Chlorpromazine; Edema; Reserpine | 1957 |
[Effect of chlorpromazine (largactil) on renal function in edematous cardiac patients].
Topics: Chlorpromazine; Edema; Edema, Cardiac; Heart Failure; Humans; Kidney | 1957 |
[Experimental pharmacological influencing of brain edema].
Topics: Brain; Brain Diseases; Brain Edema; Chlorpromazine; Edema | 1957 |
Disseminated lupus erythematosus versus drug reaction; report of a case receiving chlorpromazine.
Topics: Chlorpromazine; Edema; Humans; Lupus Erythematosus, Systemic; Purpura; Purpura, Thrombocytopenic; Th | 1959 |
[Pulmonary edema during the course of acute glomerulonephritis treated with chlorpromazine].
Topics: Acute Disease; Chlorpromazine; Edema; Glomerulonephritis; Humans; Pulmonary Edema | 1960 |
[Closed craniocerebral injuries and their therapy].
Topics: Brain Injuries; Chlorpromazine; Craniocerebral Trauma; Edema; Humans; Skull Fractures; Sorbitol | 1963 |
[ON THE MECHANISM OF INHIBITION OF INFLAMMATORY EDEMA WITH CAFFEINE, WITH REFERENCE TO SEROTONIN].
Topics: Caffeine; Chlorpromazine; Dextrans; Edema; Epinephrine; Formaldehyde; Inflammation; Rats; Research; | 1963 |
[RESEARCH ON A NEW METHOD OF EXPERIMENTAL INFLAMMATION: SUBPLANTAR EDEMA CAUSED BY CARRAGEENIN].
Topics: Adrenalectomy; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Carrageenan; Chlorpheniramine; Ch | 1964 |
EFFECT OF ANTI-INFLAMMATORY AGENTS ON CAPILLARY PERMEABILITY AND OEDEMA FORMATION.
Topics: Ammonium Compounds; Animals; Anti-Inflammatory Agents; Aspirin; Capillary Permeability; Chlorpromazi | 1964 |
CLINICAL FEATURES IN PATIENTS WITH THE CARCINOID SYNDROME.
Topics: Blood; Cardiac Catheterization; Chlorpromazine; Drug Therapy; Edema; Gastrointestinal Tract; Hydrazi | 1965 |
[On the influence of nervous factors on dextran edema of the rat paw and on the edema-inhibiting effect of chlorpromazine].
Topics: Animals; Anxiety; Chlorpromazine; Dextrans; Edema; Rats | 1959 |
Acquired local resistance to burns: prevention of its acquisition by chlorpromazine.
Topics: Animals; Burns; Chlorpromazine; Edema; Hindlimb; Male; Rats; Rats, Inbred Strains | 1983 |
Chlorpromazine-induced corneal endothelial phototoxicity.
Topics: Animals; Chlorpromazine; Cornea; Corneal Diseases; Edema; Endothelium; In Vitro Techniques; Rabbits; | 1982 |
Inflammatory activity of polymeric photoproducts of chlorpromazine.
Topics: Animals; Chlorpromazine; Edema; Histamine Release; In Vitro Techniques; Inflammation; L-Lactate Dehy | 1993 |
Effects of chlorpromazine on the enzymatic and toxic properties of the most basic phospholipase A2 from Vipera russelli snake venom.
Topics: Animals; Anticoagulants; Chlorpromazine; Edema; Hemolysis; L-Lactate Dehydrogenase; Lethal Dose 50; | 1995 |
The antagonistic effect of chlorpromazine on cadmium toxicity.
Topics: Animals; Cadmium Chloride; Chlorpromazine; Edema; Hemoglobins; Hemorrhage; Liver; Male; Necrosis; Or | 1999 |
[Pathophysiology of kidney lesions after temporary ischemia and measures for their prevention].
Topics: Animals; Chlorpromazine; Creatinine; Dogs; Edema; Electrolytes; Furosemide; Heparin; Hypothermia; Is | 1979 |
[Antiphlogistic effect of photodynamic therapy in an animal experiment].
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Chlorpromazine; Ear Diseases; Edema; Flu | 1979 |
Treatment of pre-eclampsia and eclampsia as a hypoperfusion syndrome.
Topics: Acidosis; Adult; Albumins; Blood Pressure; Chlorpromazine; Eclampsia; Edema; Female; Furosemide; Glu | 1975 |
Early inflammatory response to carrageenan in the pleural cavity and paw of rats with altered body temperature.
Topics: Amphetamine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Carrageenan; Chlorp | 1986 |
Chlorpromazine induced fluid retention masquerading as idiopathic oedema.
Topics: Body Weight; Chlorpromazine; Edema; Female; Humans; Middle Aged; Schizophrenia | 1987 |
Calmodulin inhibitors protect against cadmium-induced testicular damage in mice.
Topics: Animals; Cadmium; Cadmium Chloride; Calmodulin; Chlorpromazine; Edema; Endothelium, Vascular; Hemorr | 1987 |
Tourniquet poditis--an experimental pedal inflammation in the rat.
Topics: Animals; Anti-Bacterial Agents; Chlorpromazine; Cyproheptadine; Depression, Chemical; Dextrans; Dibe | 1969 |
Primary screening approach for anti-inflammatory agents utilizing an in vivo and a new in vitro method.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Autonomic Agents; Azo Compounds; Carrageenan; Cell-Fr | 1972 |
[Experimental studies of the influence of chlorpromazine on dextran edema of the liver].
Topics: Animals; Chlorpromazine; Chlorprothixene; Dextrans; Edema; Histamine H1 Antagonists; Liver Diseases; | 1965 |
Inhibition of the inflammatory response in the microcirculation by tourniquet shock and release of adrenal hormones. In vivo and electronmicroscopic observations.
Topics: Adrenal Glands; Adrenalectomy; Animals; Capillaries; Chlorpromazine; Cortisone; Edema; Egg White; Ep | 1969 |
Effect of steroidal and nonsteroidal anti-inflammatory compounds in a milkweed-sap-induced rat pedal edema.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Biological Assay; Chlorpromazine; Cyproheptadine; Dexame | 1973 |
Evaluation of cryogenine on rat paw thermal oedema and rat isolated uterus.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Benzocaine; Bradykinin; Burns; Chlorpromazine; Dose-Re | 1973 |
[Anti-inflammatory and analgesic effects of benzodiazepine derivatives].
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Benzazepines; Capillary Permeability; Chlorpromazine; | 1973 |
Effects of benzoquinolizine homologues on proliferative and exudative inflammation.
Topics: Adrenal Glands; Animals; Anti-Inflammatory Agents; Body Weight; Carrageenan; Catecholamines; Chlorpr | 1974 |
[Therapy of pregnancy toxemias (EPH-gestosis, preeclampsia)].
Topics: Blood Pressure Determination; Chlorpromazine; Dextrans; Diazepam; Diet Therapy; Edema; Female; Human | 1972 |
Effects of certain nonsteroid anti-inflammatory drugs, tolbutamide, and tetrahydroalstonine on blood glucose and carrageen in-induced pedal edema in rats.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Blood Glucose; Carrageenan; Chlorpromazine; Diabetes M | 1972 |
Edema and increased plasma renin activity in lithium treated patients.
Topics: Adult; Affective Symptoms; Aldosterone; Anxiety; Bipolar Disorder; Carbonates; Chlorpromazine; Diet; | 1971 |
The influence of psychopharmacologically active substances on various models of an inflammatory reaction.
Topics: Animals; Anthracenes; Arthritis; Carrageenan; Chlorpromazine; Diazepam; Edema; Foot; Hindlimb; Infla | 1971 |
Anti-inflammatory and liver sulfhydryl content-altering effects of certain nonsteroids in the rat.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Chlorpromazine; Cyproheptadine; | 1971 |
Hypoglycemic activity and pharmacological picture of 4-(1-naphthyl)butylamine derivatives.
Topics: Acetylcholine; Animals; Atropine; Behavior, Animal; Blood Glucose; Blood Pressure; Butylamines; Chem | 1966 |