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chlorpromazine and Disease

chlorpromazine has been researched along with Disease in 44 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Disease: A definite pathologic process with a characteristic set of signs and symptoms. It may affect the whole body or any of its parts, and its etiology, pathology, and prognosis may be known or unknown.

Research Excerpts

ExcerptRelevanceReference
"To assess the importance of disease-induced increases in plasma concentrations of alpha1 acid glycoprotein (an acute-phase plasma protein that binds cationic drugs), we determined binding of propranolol in plasma from 53 patients and 25 healthy volunteers."7.66Increased plasma protein binding of propranolol and chlorpromazine mediated by disease-induced elevations of plasma alpha1 acid glycoprotein. ( Borgá, O; Johansson, C; Odar-Cederlöf, I; Piafsky, KM; Sjöqvist, F, 1978)
"To assess the importance of disease-induced increases in plasma concentrations of alpha1 acid glycoprotein (an acute-phase plasma protein that binds cationic drugs), we determined binding of propranolol in plasma from 53 patients and 25 healthy volunteers."3.66Increased plasma protein binding of propranolol and chlorpromazine mediated by disease-induced elevations of plasma alpha1 acid glycoprotein. ( Borgá, O; Johansson, C; Odar-Cederlöf, I; Piafsky, KM; Sjöqvist, F, 1978)

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-199043 (97.73)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (2.27)2.80

Authors

AuthorsStudies
Brzeszczyńska, J1
Brzeszczyński, F1
Samuel, K1
Morgan, K1
Morley, SD1
Plevris, JN1
Hayes, PC1
HOWELL, TH1
HARTH, JA1
DIETRICH, M1
BASMAJIAN, JV1
SZATMARI, A1
GROSS, D1
HERING, HJ1
ROVINSKI, J1
KURLAND, AA1
SETTEL, E1
SOLLGRUBER, A1
NOGUER-MORE, S1
MENDES, E1
SAMPAIO, SA1
FARIA, SG1
COSTE, F1
DELBARRE, F1
MASSIAS, P1
COLLIER, G1
DEFER, B1
LABORDE, P1
FONG, TC1
LAUNAY, J1
DESPAUTRE, M1
CONRAD, K2
DOMANOWSKY, K2
WIESER, S2
NICHAMIN, SJ2
GUIRAL, RJ2
STECK, H3
BOURGUIGNON, A2
DELAY, J2
DENIKER, P2
LEMPERIERE, T2
BARTHOLOMEW, LG1
CAIN, JC1
FREY, B1
MAUREL, H1
SPIELMANN, JP1
HERSHKOWITZ, M1
BENKO, S1
ABRANDI, E1
VARGHA, M1
VON DITFURTH, H1
GIBSON, JW1
BLUESTONE, SS1
LOWMAN, EW1
FREYHAN, FA1
FRITZ, R1
ROTHAUGE, CF1
BARR, MN1
MALLER, O1
CONSTANTINESCO, GN1
POURSINES, Y1
ROGER, J1
TEMKOV, I1
BOIADZHIEVA, M1
YIM, BJ1
JAENIKE, JR1
VAN ROOTSELAAR, FJ1
KLEINT, W1
DZIALEK, E1
SZULC, J1
SOBEL, DE1
SIGWALD, J1
BOUTTIER, D1
RAYMONDEAUD, C1
WOLF, JW1
SEAGER, CP1
Letailleur, M1
Morin, J1
Demay, J1
HODGES, RJ1
Piafsky, KM1
Borgá, O1
Odar-Cederlöf, I1
Johansson, C1
Sjöqvist, F1
König, MP1

Other Studies

44 other studies available for chlorpromazine and Disease

ArticleYear
Validation of Reference Genes for Gene Expression Studies by RT-qPCR in HepaRG Cells during Toxicity Testing and Disease Modelling.
    Cells, 2020, 03-21, Volume: 9, Issue:3

    Topics: Acetaminophen; Adenosine Triphosphate; Cell Line; Cell Survival; Chlorpromazine; Disease; Gene Expre

2020
The use of chlorpromazine in geriatrics.
    The Practitioner, 1954, Volume: 173, Issue:1034

    Topics: Aged; Autonomic Agents; Chlorpromazine; Disease; Geriatrics

1954
Effect of largactil (chlorpromazine) on human spasticity and electromyogram; preliminary report.
    A.M.A. archives of neurology and psychiatry, 1955, Volume: 73, Issue:2

    Topics: Brain Diseases; Cerebral Cortex; Chlorpromazine; Disease; Electromyography; Muscle Spasticity; Spasm

1955
[The extent of control of focal infection in the region of the alveolar processes].
    Deutsche zahnarztliche Zeitschrift, 1955, Jul-01, Volume: 10, Issue:13

    Topics: Alveolar Process; Chlorpromazine; Disease; Focal Infection; Humans; Jaw Diseases; Penicillins; Tooth

1955
[Therapeutic trials with chlorpromazine in cerebromeningeal complications in premature infants].
    Pediatrie, 1955, Volume: 10, Issue:5

    Topics: Brain; Brain Diseases; Chlorpromazine; Disease; Humans; Infant, Newborn; Infant, Premature; Infant,

1955
Chlorpromazine in the management of the institutionalized aged psychiatric patient with chronic brain syndrome.
    Diseases of the nervous system, 1955, Volume: 16, Issue:12

    Topics: Aged; Brain; Brain Damage, Chronic; Chlorpromazine; Disease; Disease Management; Humans; Mental Diso

1955
Chlorpromazine in the treatment of senile agitation.
    GP, 1955, Volume: 12, Issue:6

    Topics: Aged; Chlorpromazine; Disease; Humans; Mental Disorders; Psychomotor Agitation

1955
[Experiences with the phenothiazine sleep therapy in internal medicine].
    Wiener medizinische Wochenschrift (1946), 1955, Sep-24, Volume: 105, Issue:38-39

    Topics: Chlorpromazine; Disease; Internal Medicine; Phenothiazines; Sleep

1955
[Contact dermatitis caused by chlorpromazine; first observations].
    Actas dermo-sifiliograficas, 1955, Volume: 47, Issue:2

    Topics: Chlorpromazine; Dermatitis; Dermatitis, Contact; Disease; Humans; Physicians

1955
[Chlorpromazine dermatitis].
    Revista da Associacao Medica Brasileira, 1955, Volume: 2, Issue:1

    Topics: Chloramphenicol; Chlorpromazine; Dermatitis; Dermatitis, Contact; Disease; Humans; Physicians

1955
[Remarks on a case of painful dystrophy of the hand].
    Revue du rhumatisme et des maladies osteo-articulaires, 1956, Volume: 23, Issue:1

    Topics: Autonomic Nervous System Diseases; Chlorpromazine; Disease; Feeding and Eating Disorders; Hand; Huma

1956
[Clinical aspects of the syndrome of extrapyramidal behavior appearing during treatment by largactil].
    Journal de medecine de Bordeaux et du Sud-Ouest, 1956, Volume: 133, Issue:3

    Topics: Basal Ganglia Diseases; Chlorpromazine; Disease; Extrapyramidal Tracts; Humans; Syndrome

1956
Chlorpromazine and reserpine in geriatric patients.
    The Medical annals of the District of Columbia, 1956, Volume: 25, Issue:5

    Topics: Aged; Antihypertensive Agents; Chlorpromazine; Disease; Mental Disorders; Patients; Reserpine; Secol

1956
[Psychomotor and extraphyramidal syndromes during prolonged chlorpromazine treatment].
    Annales medico-psychologiques, 1956, Volume: 114, Issue:2

    Topics: Basal Ganglia Diseases; Brain; Brain Diseases; Chlorpromazine; Disease; Extrapyramidal Tracts; Human

1956
[Extrapyramidal seizures caused by phenothiazine treatment].
    Fortschritte der Neurologie, Psychiatrie, und ihrer Grenzgebiete, 1956, Volume: 24, Issue:9

    Topics: Basal Ganglia Diseases; Chlorpromazine; Disease; Extrapyramidal Tracts; Humans; Phenothiazines; Psyc

1956
[Extrapyramidal seizures caused by phenothiazine treatment].
    Fortschritte der Neurologie, Psychiatrie, und ihrer Grenzgebiete, 1956, Volume: 24, Issue:9

    Topics: Basal Ganglia Diseases; Chlorpromazine; Disease; Extrapyramidal Tracts; Humans; Phenothiazines; Psyc

1956
[Extrapyramidal seizures caused by phenothiazine treatment].
    Fortschritte der Neurologie, Psychiatrie, und ihrer Grenzgebiete, 1956, Volume: 24, Issue:9

    Topics: Basal Ganglia Diseases; Chlorpromazine; Disease; Extrapyramidal Tracts; Humans; Phenothiazines; Psyc

1956
[Extrapyramidal seizures caused by phenothiazine treatment].
    Fortschritte der Neurologie, Psychiatrie, und ihrer Grenzgebiete, 1956, Volume: 24, Issue:9

    Topics: Basal Ganglia Diseases; Chlorpromazine; Disease; Extrapyramidal Tracts; Humans; Phenothiazines; Psyc

1956
Chlorpromazine in the treatment of mild behavior disturbances.
    Journal - Michigan State Medical Society, 1956, Volume: 55, Issue:12

    Topics: Abdomen; Attention Deficit and Disruptive Behavior Disorders; Child; Child Behavior Disorders; Chlor

1956
Chlorpromazine in the treatment of mild behavior disturbances.
    Journal - Michigan State Medical Society, 1956, Volume: 55, Issue:12

    Topics: Abdomen; Attention Deficit and Disruptive Behavior Disorders; Child; Child Behavior Disorders; Chlor

1956
Chlorpromazine in the treatment of mild behavior disturbances.
    Journal - Michigan State Medical Society, 1956, Volume: 55, Issue:12

    Topics: Abdomen; Attention Deficit and Disruptive Behavior Disorders; Child; Child Behavior Disorders; Chlor

1956
Chlorpromazine in the treatment of mild behavior disturbances.
    Journal - Michigan State Medical Society, 1956, Volume: 55, Issue:12

    Topics: Abdomen; Attention Deficit and Disruptive Behavior Disorders; Child; Child Behavior Disorders; Chlor

1956
[Use of chlorpromazine in the psychosomatic type of autonomic dystonias].
    L'Encephale, 1956, Volume: 45, Issue:4

    Topics: Autonomic Nervous System; Autonomic Nervous System Diseases; Chlorpromazine; Disease; Dystonia; Huma

1956
[Use of chlorpromazine in the psychosomatic type of autonomic dystonias].
    L'Encephale, 1956, Volume: 45, Issue:4

    Topics: Autonomic Nervous System; Autonomic Nervous System Diseases; Chlorpromazine; Disease; Dystonia; Huma

1956
[Use of chlorpromazine in the psychosomatic type of autonomic dystonias].
    L'Encephale, 1956, Volume: 45, Issue:4

    Topics: Autonomic Nervous System; Autonomic Nervous System Diseases; Chlorpromazine; Disease; Dystonia; Huma

1956
[Use of chlorpromazine in the psychosomatic type of autonomic dystonias].
    L'Encephale, 1956, Volume: 45, Issue:4

    Topics: Autonomic Nervous System; Autonomic Nervous System Diseases; Chlorpromazine; Disease; Dystonia; Huma

1956
[Extrapyramidal syndrome in chlorpromazine and serpasil therapy; clinical symptomatology and therapeutic role].
    L'Encephale, 1956, Volume: 45, Issue:4

    Topics: Basal Ganglia Diseases; Chlorpromazine; Disease; Extrapyramidal Tracts; Humans; Reserpine; Schizophr

1956
[Extrapyramidal syndrome in chlorpromazine and serpasil therapy; clinical symptomatology and therapeutic role].
    L'Encephale, 1956, Volume: 45, Issue:4

    Topics: Basal Ganglia Diseases; Chlorpromazine; Disease; Extrapyramidal Tracts; Humans; Reserpine; Schizophr

1956
[Extrapyramidal syndrome in chlorpromazine and serpasil therapy; clinical symptomatology and therapeutic role].
    L'Encephale, 1956, Volume: 45, Issue:4

    Topics: Basal Ganglia Diseases; Chlorpromazine; Disease; Extrapyramidal Tracts; Humans; Reserpine; Schizophr

1956
[Extrapyramidal syndrome in chlorpromazine and serpasil therapy; clinical symptomatology and therapeutic role].
    L'Encephale, 1956, Volume: 45, Issue:4

    Topics: Basal Ganglia Diseases; Chlorpromazine; Disease; Extrapyramidal Tracts; Humans; Reserpine; Schizophr

1956
[Extrapyramidal movement disorders during chlorpromazine and reserpine therapy; clinical and electromyographic studies].
    L'Encephale, 1956, Volume: 45, Issue:4

    Topics: Basal Ganglia Diseases; Chlorpromazine; Disease; Extrapyramidal Tracts; Humans; Movement Disorders;

1956
[Extrapyramidal movement disorders during chlorpromazine and reserpine therapy; clinical and electromyographic studies].
    L'Encephale, 1956, Volume: 45, Issue:4

    Topics: Basal Ganglia Diseases; Chlorpromazine; Disease; Extrapyramidal Tracts; Humans; Movement Disorders;

1956
[Extrapyramidal movement disorders during chlorpromazine and reserpine therapy; clinical and electromyographic studies].
    L'Encephale, 1956, Volume: 45, Issue:4

    Topics: Basal Ganglia Diseases; Chlorpromazine; Disease; Extrapyramidal Tracts; Humans; Movement Disorders;

1956
[Extrapyramidal movement disorders during chlorpromazine and reserpine therapy; clinical and electromyographic studies].
    L'Encephale, 1956, Volume: 45, Issue:4

    Topics: Basal Ganglia Diseases; Chlorpromazine; Disease; Extrapyramidal Tracts; Humans; Movement Disorders;

1956
Abdominal pain following use of chlorpromazine.
    Journal of the American Medical Association, 1957, Mar-02, Volume: 163, Issue:9

    Topics: Abdomen; Abdominal Pain; Chlorpromazine; Disease; Hepatitis; Hepatitis A; Humans

1957
[Oculogyric crises during successive treatment with reserpine & chlorpromazine].
    Annales medico-psychologiques, 1957, Volume: 115, Issue:3

    Topics: Chlorpromazine; Disease; Dystonic Disorders; Eye Diseases; Eye Movements; Humans; Muscles; Oculomoto

1957
Unusual reaction to thorazine.
    Annals of internal medicine, 1957, Volume: 46, Issue:4

    Topics: Chlorpromazine; Disease; Drug Eruptions; Hand; Humans

1957
[Therapy of autonomic crisis with hibernating drugs].
    Orvosi hetilap, 1956, Oct-21, Volume: 97, Issue:43

    Topics: Autonomic Agents; Autonomic Nervous System; Chlorpromazine; Diencephalon; Disease; Phenothiazines

1956
[Oculogyric crisis in obsessive-compulsive neurosis caused by megaphen; problems of the place of obsessive-compulsive neurosis in classification systems].
    Der Nervenarzt, 1957, Apr-20, Volume: 28, Issue:4

    Topics: Chlorpromazine; Disease; Humans; Neurotic Disorders; Obsessive-Compulsive Disorder; Oculomotor Muscl

1957
Zoxazolamine and/or chlorpromazine for muscle spasm.
    Journal of the American Medical Association, 1957, Sep-07, Volume: 165, Issue:1

    Topics: Chlorpromazine; Disease; Muscle Relaxants, Central; Muscles; Muscular Diseases; Nervous System Disea

1957
[Psychomotility, extrapyramidal syndrome and mode of action of neuroleptic therapies; chlorpromazine, reserpine and prochlorperazine].
    Der Nervenarzt, 1957, Nov-20, Volume: 28, Issue:11

    Topics: Antipsychotic Agents; Basal Ganglia Diseases; Chlorpromazine; Disease; Extrapyramidal Tracts; Humans

1957
[Animal experimental studies on the influence of chlorpromazine (megaphen) on peritoneal adhesions in Lembert's suture].
    Der Anaesthesist, 1957, Volume: 6, Issue:6

    Topics: Animals; Chlorpromazine; Disease; Peritoneal Diseases; Peritoneum; Sutures; Tissue Adhesions

1957
Effect of chlorpromazine on muscle spasm in human tetanus.
    Lancet (London, England), 1958, May-10, Volume: 1, Issue:7028

    Topics: Chlorpromazine; Disease; Muscles; Muscular Diseases; Nervous System Diseases; Spasm; Tetanus; Tetanu

1958
[Acute extrapyramidal accidents in the course of chlorpromazine treatment].
    Psychiatria et neurologia, 1958, Volume: 135, Issue:3

    Topics: Accidents; Basal Ganglia Diseases; Chlorpromazine; Disease; Extrapyramidal Tracts; Humans

1958
[Thalamic syndrome with facial neuralgia; treatment by chlorpromazine].
    Revue d'oto-neuro-ophtalmologie, 1957, Volume: 29, Issue:8

    Topics: Chlorpromazine; Disease; Face; Facial Neuralgia; Thalamic Diseases

1957
[Certain toxic manifestations during phenothiazine derivative therapy].
    Suvremenna meditsina, 1957, Volume: 8, Issue:10

    Topics: Antipsychotic Agents; Basal Ganglia Diseases; Chlorpromazine; Disease; Extrapyramidal Tracts; Hepati

1957
Idiopathic hypoparathyroidism presenting as a psychosis and complicated by chlorpromazine jaundice.
    The American journal of medicine, 1958, Volume: 25, Issue:3

    Topics: Chlorpromazine; Disease; Humans; Hypoparathyroidism; Jaundice; Medical Records; Mental Disorders; Pa

1958
[Umbilical tetanus, treated with chlorpromazine].
    Nederlands tijdschrift voor geneeskunde, 1958, Oct-25, Volume: 102, Issue:43

    Topics: Child; Chlorpromazine; Disease; Humans; Infant; Tetanus; Tetanus Toxoid; Umbilicus

1958
[Propaphenin drops and suppositories in the therapy of habitual vomiting, pylorospasm and anorexia nervosa in infants].
    Zeitschrift fur arztliche Fortbildung (Berlin), 1960, Jul-01, Volume: 54

    Topics: Anorexia Nervosa; Child; Chlorpromazine; Disease; Humans; Infant; Pessaries; Pylorus; Suppositories;

1960
[A case of thalamic syndrome treated successfully with largactil].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1959, Oct-05, Volume: 14

    Topics: Chlorpromazine; Disease; Thalamic Diseases; Thalamus

1959
Fetal damage due to ECT, insulin coma, chlorpromazine, or reserpine.
    A.M.A. archives of general psychiatry, 1960, Volume: 2

    Topics: Chlorpromazine; Convulsive Therapy; Disease; Electroconvulsive Therapy; Fetal Diseases; Fetus; Human

1960
[Chlorproethazine. Its importance in neurology].
    La Presse medicale, 1961, Nov-18, Volume: 69

    Topics: Chlorpromazine; Disease; Movement Disorders; Neurology; Pyramidal Tracts; Tranquilizing Agents

1961
The irritable colon syndrome. Treatment with chlorpromazine and other phenothiazine drugs.
    Missouri medicine, 1962, Volume: 59

    Topics: Antipsychotic Agents; Chlorpromazine; Colon; Disease; Humans; Irritable Bowel Syndrome; Phenothiazin

1962
[Extrapyramidal and diencephalic syndrome in the course of largactil and serpasil treatments].
    Annales medico-psychologiques, 1954, Volume: 112, Issue:2 5

    Topics: Antihypertensive Agents; Basal Ganglia Diseases; Chlorpromazine; Diencephalon; Disease; Extrapyramid

1954
Chlorpromazine in treatment of elderly psychotic women.
    British medical journal, 1955, Apr-09, Volume: 1, Issue:4918

    Topics: Aged; Chlorpromazine; Disease; Female; Humans; Mental Disorders; Psychotic Disorders

1955
[Extrapyramidal-like syndromes, oculogyral seizures and chlorpromazine].
    Annales medico-psychologiques, 1955, Volume: 113 1, Issue:4

    Topics: Basal Ganglia Diseases; Chlorpromazine; Disease; Extrapyramidal Tracts; Eye Movements; Humans; Oculo

1955
Gangrene of forearm after intramuscular chlorpromazine.
    British medical journal, 1959, Nov-07, Volume: 2, Issue:5157

    Topics: Chlorpromazine; Disease; Forearm; Gangrene; Humans; Injections, Intramuscular

1959
Increased plasma protein binding of propranolol and chlorpromazine mediated by disease-induced elevations of plasma alpha1 acid glycoprotein.
    The New England journal of medicine, 1978, Dec-28, Volume: 299, Issue:26

    Topics: Adult; Aged; alpha-Macroglobulins; Arthritis; Chlorpromazine; Crohn Disease; Disease; Female; Humans

1978
[Physiology and pathophysiology of prolactin].
    International pharmacopsychiatry, 1978, Volume: 13 Suppl 1

    Topics: Chlorpromazine; Disease; Humans; Prolactin

1978