chlorpromazine has been researched along with Diabetes Mellitus in 29 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To examine quantitatively the association between glucose intolerance including diabetes mellitus and the use of the atypical antipsychotics clozapine, olanzapine or risperidone, and to identify possible risk factors for the development of glucose intolerance during treatment with these drugs." | 3.71 | Glucose intolerance with atypical antipsychotics. ( Hägg, S; Hedenmalm, K; Mortimer, O; Spigset, O; Ståhl, M, 2002) |
| "In three groups of normal subjects and in one group of patients with latent diabetes mellitus a study has been made of the effects of chlorpromazine (CPZ) on blood glucose and plasma insulin." | 3.65 | Effect of chlorpromazine on blood glucose and plasma insulin in man. ( Basso, M; Erle, G; Federspil, G; Scandellari, C; Sicolo, N, 1977) |
| " The atypicals cause fewer extrapyramidal symptoms and tardive dyskinesia, but there is growing concern regarding the significant long-term metabolic and cardiac adverse effects of these novel antipsychotics." | 2.42 | From chlorpromazine to clozapine--antipsychotic adverse effects and the clinician's dilemma. ( Abidi, S; Bhaskara, SM, 2003) |
| "Chlorpromazine has very likely been responsible for a considerable increase in the prevalence of diabetes in hospitalized psychotics, while antidepressants can produce useful improvement of diabetic control, especially in brittle diabetics." | 1.26 | The effects of psychotropic drugs and diuretics on blood glucose levels in diabetes mellitus. ( Zumoff, B, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (82.76) | 18.7374 |
| 1990's | 1 (3.45) | 18.2507 |
| 2000's | 4 (13.79) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hedenmalm, K | 1 |
| Hägg, S | 1 |
| Ståhl, M | 1 |
| Mortimer, O | 1 |
| Spigset, O | 1 |
| LORENZEN, J | 1 |
| REMVIG, J | 1 |
| BOSZORMENYI, Z | 1 |
| HORN, Z | 1 |
| DER, P | 1 |
| BRUNECKER, G | 1 |
| ALANT, O | 1 |
| GEORGE, CW | 1 |
| STOWERS, JM | 1 |
| BEWSHER, PD | 1 |
| BRACKENRIDGE, RG | 1 |
| CANIVET, J | 1 |
| LUEDTKE, E | 1 |
| ARNESON, GA | 1 |
| ZSCHORNACK, MR | 1 |
| JAROSS, W | 1 |
| SOLTI, F | 2 |
| ISKUM, M | 2 |
| KRASZNAI, I | 2 |
| MARK, G | 2 |
| REV, J | 2 |
| FOELDESY, K | 1 |
| HERMANN, R | 2 |
| FOELDESSY, K | 1 |
| RENKER, U | 1 |
| Amdisen, A | 1 |
| SHLEVIN, EL | 1 |
| ZAROWITZ, H | 1 |
| WEISENFELD, S | 1 |
| GOLDNER, MG | 1 |
| Dunlop, BW | 1 |
| Sternberg, M | 1 |
| Phillips, LS | 1 |
| Andersen, J | 1 |
| Duncan, E | 1 |
| Abidi, S | 1 |
| Bhaskara, SM | 1 |
| Cohen, D | 1 |
| Batstra, MR | 1 |
| Gispen-de Wied, CC | 1 |
| Juhan, I | 1 |
| Vague, P | 1 |
| Buonocore, M | 1 |
| Moulin, JP | 1 |
| Calas, MF | 1 |
| Vialettes, B | 1 |
| Verdot, JJ | 1 |
| Zumoff, B | 1 |
| Erle, G | 1 |
| Basso, M | 1 |
| Federspil, G | 1 |
| Sicolo, N | 1 |
| Scandellari, C | 1 |
| Vargas, I | 1 |
| Kawada, ME | 1 |
| Mayer, GA | 1 |
| Noble, IM | 1 |
| Wada, T | 1 |
| Takasu, S | 1 |
| Kinoshita, H | 1 |
| Uchiya, T | 1 |
| Imamura, H | 1 |
| Hellman, B | 1 |
| Lernmark, A | 1 |
| Sehlin, J | 1 |
| Täljedal, IB | 1 |
| Thonnard-Neumann, E | 1 |
| Schwarz, L | 1 |
| Munoz, R | 1 |
| Korenyi, C | 1 |
| Lowenstein, B | 1 |
| Burke, G | 1 |
| Halko, A | 1 |
2 reviews available for chlorpromazine and Diabetes Mellitus
| Article | Year |
|---|---|
From chlorpromazine to clozapine--antipsychotic adverse effects and the clinician's dilemma.
Topics: Antipsychotic Agents; Chlorpromazine; Clozapine; Diabetes Mellitus; Humans; Hyperlipidemias; Long QT | 2003 |
[Gastrin secretion and clinical medicine].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Chlorpromazine; Circadian Rhythm; Cold Temperature | 1972 |
27 other studies available for chlorpromazine and Diabetes Mellitus
| Article | Year |
|---|---|
Glucose intolerance with atypical antipsychotics.
Topics: Adverse Drug Reaction Reporting Systems; Antipsychotic Agents; Bayes Theorem; Benzodiazepines; Chlor | 2002 |
Diabetes mellitus in a psychotic patient with recovery during chlorpromazine therapy.
Topics: Chlorpromazine; Diabetes Mellitus; Humans; Medical Records; Mental Disorders; Psychotherapy; Psychot | 1957 |
[Diabetes occurring in connection with largactil therapy].
Topics: Chlorpromazine; Diabetes Mellitus | 1957 |
Central scotomata due to chlorpropamide (Diabenese). Case report.
Topics: Chlorpromazine; Chlorpropamide; Diabetes Mellitus; Humans; Scotoma | 1963 |
Trial of chlorpropamide in subclinical diabetes.
Topics: Chlorpromazine; Chlorpropamide; Diabetes Mellitus | 1962 |
[Oral medication of diabetes mellitus].
Topics: Carbutamide; Chlorpromazine; Diabetes Mellitus; Humans; Hypoglycemic Agents; Sulfonylurea Compounds; | 1962 |
[ON THE CONTROL OF RASTINON LOAD IN DIABETICS BY CHLOPROMAZINE].
Topics: Chlorpromazine; Diabetes Mellitus; Humans; Tolbutamide | 1963 |
PHENOTHIAZINE DERIVATIVES AND GLUCOSE METABOLISM.
Topics: Animals; Bipolar Disorder; Carbohydrate Metabolism; Chlorpromazine; Diabetes Mellitus; Furunculosis; | 1964 |
[DRAMATIC INCIDENTS DURING THE TREATMENT WITH ORAL ANTIDIABETICS].
Topics: Acidosis; Carbohydrates; Chlorpromazine; Diabetes Mellitus; Diabetic Coma; Diabetic Ketoacidosis; Ge | 1963 |
[EFFECT OF CHLORPROMAZINE (HIBERNAL) ON THE CIRCULATION AND ON THE OXYGEN CONSUMPTION BY MUSCLES OF EXTREMITIES].
Topics: Animals; Arm; Arteriosclerosis; Blood Circulation; Cardiovascular Diseases; Chlorpromazine; Colitis; | 1964 |
EFFECT OF CHLORPROMAZINE ON PERIPHERAL CIRCULATION AND ON THE OXYGEN CONSUMPTION OF THE EXTREMITIES MUSCLES.
Topics: Arteriosclerosis; Biomedical Research; Blood Circulation; Blood Flow Velocity; Blood Pressure; Blood | 1964 |
["ON CASE REPORTS ON SIDE-EFFECTS OF PHENOTHIAZINES"].
Topics: Carbohydrate Metabolism; Chlorpromazine; Diabetes Mellitus; Hyperglycemia; Insulin; Lipid Metabolism | 1964 |
DIABETES MELLITUS AS A SIDE EFFECT OF TREATMENT WITH TRICYCLIC NEUROLEPTICS.
Topics: Antipsychotic Agents; Chlorpromazine; Clopenthixol; Diabetes Mellitus; Drug Therapy; Glucose Toleran | 1964 |
Clinical experiences with chlorpropamide in management of diabetes mellitus.
Topics: Chlorpromazine; Chlorpropamide; Diabetes Mellitus; Humans | 1960 |
Disturbed glucose metabolism among patients taking olanzapine and typical antipsychotics.
Topics: Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Cohort Studies; Depressive Disorder; Diabetes | 2003 |
Immunological characteristics of diabetes in schizophrenia.
Topics: Antipsychotic Agents; Autoantibodies; Chlorpromazine; Diabetes Complications; Diabetes Mellitus; Hum | 2005 |
Effects of insulin on erythrocyte deformability in diabetics--relationship between erythrocyte deformability and platelet aggregation.
Topics: 2,3-Diphosphoglycerate; Blood Glucose; Chlorpromazine; Diabetes Mellitus; Diphosphoglyceric Acids; E | 1981 |
The effects of psychotropic drugs and diuretics on blood glucose levels in diabetes mellitus.
Topics: Blood Glucose; Chlorpromazine; Diabetes Mellitus; Humans; Hyperglycemia; Hypoglycemia; Psychotropic | 1979 |
Effect of chlorpromazine on blood glucose and plasma insulin in man.
Topics: Administration, Oral; Blood Glucose; Chlorpromazine; Diabetes Mellitus; Glucose; Glucose Tolerance T | 1977 |
Adrenal and liver participation in the rat's post-stress diabetic response.
Topics: Adrenal Glands; Adrenalectomy; Animals; Blood Glucose; Blood Proteins; Chlorpromazine; Diabetes Mell | 1976 |
Chlorpropamide or chlorpromazine?
Topics: Blindness; Chlorpromazine; Chlorpropamide; Diabetes Mellitus; Humans; Male; Middle Aged; Sleep; Term | 1991 |
Prescribing in pregnancy.
Topics: Carbimazole; Chlorpromazine; Diabetes Mellitus; Diazepam; Drug Prescriptions; Epilepsy; Female; Fetu | 1974 |
The pancreatic -cell recognition of insulin secretagogues. V. Binding and stimulatory action of phlorizin.
Topics: Animals; Antimycin A; Arginine; Carbon Isotopes; Chloromercuribenzoates; Chlorpromazine; Diabetes Me | 1972 |
Phenothiazines and diabetes in hospitalized women.
Topics: Age Factors; Chlorpromazine; Diabetes Mellitus; Female; Glycosuria; Gonads; Humans; Hyperglycemia; M | 1968 |
Blood sugar levels in patients treated with chlorpromazine.
Topics: Blood Glucose; Chlorpromazine; Diabetes Mellitus; Humans; Mental Disorders | 1968 |
Chlorpromazine induced diabetes.
Topics: Aged; Blood Glucose; Chlorpromazine; Diabetes Mellitus; Female; Glucose; Humans; Middle Aged | 1968 |
Dynamic clinical studies with radioisotopes and the scintillation camera. II. Rose bengal I-131 liver function studies.
Topics: Aged; Alcoholism; Chlorpromazine; Chlorpropamide; Cholestasis; Diabetes Mellitus; Diagnosis, Differe | 1966 |