Compounds > chlorpromazine
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chlorpromazine and Dermatitis Medicamentosa

chlorpromazine has been researched along with Dermatitis Medicamentosa in 34 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Research Excerpts

ExcerptRelevanceReference
"By a photohemolysis test we assessed in vitro the phototoxic properties of 12 phenothiazines (chlorpromazine, dixyrazine, fluphenazine, levomepromazine, perazine, perphenazine, promazine, promethazine, prothipendyl, thioridazine, trifluoperazine, triflupromazine) and 5 thioxanthenes (chlorprothixene, clopenthixol, flupenthixol, thiothixene, zuclopenthixol)."3.69Phototoxic properties of neuroleptic drugs. ( Bindl, A; Eberlein-König, B; Przybilla, B, 1997)
" She had a combination of three types of hypersensitivity to chlorpromazine, ie, allergic contact dermatitis, photocontact dermatitis, and immediate allergic photosensitivity."3.65Chlorpromazine photoallergy. Coexistence of immediate and delayed type. ( Horio, T, 1975)
"A 57-year-old schizoaffective disorder patient was placed on chlorpromazine because of its sedative properties and low profile for extrapyramidal side effects."1.29Cutaneous and ocular changes associated with the use of chlorpromazine. ( Berk, MA; Mosnaim, AD; Richer, S; Wolf, ME, 1993)
" While the mean age and mean duration of hospitalization in the skin-pigmented population was slightly higher and larger than in the total population of our survey, no definitive relationships between sex, diagnosis, drugs and dosage of medication were revealed."1.27Neuroleptic-induced skin pigmentation in chronic hospitalized schizophrenic patients. ( Ban, TA; Guy, W; Wilson, WH, 1985)
" Preirradiated CPZ was not toxic to the yeast culture."1.26Phenothiazine phototoxicity: toxic chlorpromazine photoproducts. ( Ljunggren, B, 1977)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199029 (85.29)18.7374
1990's5 (14.71)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
ZAVARINI, G1
SINGER, JI1
MERLIS, S1
HERSHKOWITZ, M1
KALAMKARIAN, AA2
STOIANOV, BG1
CAFFEY, EM1
LINDEMAN, JE1
ROBERTS, AS1
PERILLO, AE1
CALNAN, CD1
FRAIN-NELL, W1
CUTHBERT, JW1
IVANOVA, NN1
SHTEIN, VV1
TASZYCKA, W1
PASCHOUD, JM1
KAUPPINEN, K1
RECHARDT, L1
EPSTEIN, S1
DICKEY, RF1
HARTMAN, DL1
CAIRNS, RJ1
CAPOORE, HS1
GREGORY, ID1
BAILEY, G1
ROSENBAUM, JM1
ANDERSON, B1
WOROBEC, T1
POTTIER, C1
DU COUEDIC, H1
LANSELLE, ME1
LEVKOVICH-SOKOLOVA, AP1
Sandler, BB1
Shersneva, AD1
Faucher, L1
Marcoux, D1
Burrows, NP1
Ratnavel, RC1
Norris, PG1
Wolf, ME1
Richer, S1
Berk, MA1
Mosnaim, AD1
Eberlein-König, B1
Bindl, A1
Przybilla, B1
Ljunggren, B1
Lam, SK1
Tomlinson, DR1
Horio, T1
Loesche, C1
Dejobert, Y1
Thomas, P1
Ban, TA1
Guy, W1
Wilson, WH1
Stern, WK1
Francesconi, G1
Di Tizio, A1
Cameo, D1
Clark, ML1
Ramsey, HR1
Ragland, RE1
Rahhal, DK1
Serafetinides, EA1
Costiloe, JP1
Davies, GE1
Holmes, JE1
Raskin, A1

Reviews

1 review available for chlorpromazine and Dermatitis Medicamentosa

ArticleYear
Drug-induced immunological effects on the liver.
    British journal of anaesthesia, 1972, Volume: 44, Issue:9

    Topics: Aminosalicylic Acids; Anaphylaxis; Chemical and Drug Induced Liver Injury; Chlorpromazine; Drug Erup

1972

Trials

2 trials available for chlorpromazine and Dermatitis Medicamentosa

ArticleYear
Chlorpromazine in chronic schizophrenia: behavioral dose-response relationships.
    Psychopharmacologia, 1970, Volume: 18, Issue:3

    Topics: Adult; Agranulocytosis; Analysis of Variance; Anemia; Behavior; Chlorpromazine; Chronic Disease; Cli

1970
A guide for drug use in depressive disorders.
    The American journal of psychiatry, 1974, Volume: 131, Issue:2

    Topics: Adolescent; Adult; Aged; Anxiety; Chlorpromazine; Clinical Trials as Topic; Depression; Diazepam; Dr

1974

Other Studies

31 other studies available for chlorpromazine and Dermatitis Medicamentosa

ArticleYear
[Allergy to largactil; eczematous contact reactions].
    Minerva dermatologica, 1955, Volume: 30, Issue:7

    Topics: Chlorpromazine; Drug Eruptions; Eczema; Humans; Hypersensitivity; Immune System Diseases

1955
Skin sensitivity to chlorpromazine.
    New York state journal of medicine, 1956, Apr-15, Volume: 56, Issue:8

    Topics: Chlorpromazine; Drug Eruptions; Humans; Skin Physiological Phenomena

1956
Unusual reaction to thorazine.
    Annals of internal medicine, 1957, Volume: 46, Issue:4

    Topics: Chlorpromazine; Disease; Drug Eruptions; Hand; Humans

1957
[Dermatitis caused by aminazine].
    Sovetskaia meditsina, 1957, Volume: 21, Issue:9

    Topics: Chlorpromazine; Dermatitis; Drug Eruptions; Humans; Medical Records

1957
Thorazine photosensitivity.
    Diseases of the nervous system, 1958, Volume: 19, Issue:6

    Topics: Chlorpromazine; Dermatitis, Phototoxic; Drug Eruptions; Humans; Medical Records; Photosensitivity Di

1958
[Prevention of disorders caused by chlorpromazine].
    La Semana medica, 1960, Nov-03, Volume: 117

    Topics: Biomedical Research; Chlorpromazine; Drug Eruptions; Jaundice

1960
Occupational dermatitis from chlorpromazine.
    Transactions of the St. John's Hospital Dermatological Society, 1962, Volume: 48

    Topics: Chlorpromazine; Dermatitis, Contact; Dermatitis, Occupational; Drug Eruptions; Humans

1962
[On the prevention of aminazin dermatitis induced by solar radiation].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1963, Volume: 63

    Topics: Biomedical Research; Chlorpromazine; Dermatitis; Drug Eruptions; Humans; Solar Energy; Sunlight

1963
[Largactil sensitization].
    Przeglad dermatologiczny, 1961, Volume: 48 (Suppl)

    Topics: Chlorpromazine; Drug Eruptions; Humans; Learning; Nervous System Physiological Phenomena

1961
[SOME CASES OF CONTACT ECZEMA WITH GROUP SENSITIZATION].
    Dermatologica, 1963, Volume: 127

    Topics: 4-Aminobenzoic Acid; Aminobenzoates; Aniline Compounds; Antipsychotic Agents; Azo Compounds; Camphor

1963
[DRUG-INDUCED SKIN ERUPTIONS TREATED AT THE HELSINKI UNIVERSITY DERMATOLOGICAL CLINIC 1956-1960].
    Duodecim; laaketieteellinen aikakauskirja, 1963, Volume: 79

    Topics: Acne Vulgaris; Anti-Bacterial Agents; Barbiturates; Chlorpromazine; Drug Eruptions; Drug Hypersensit

1963
THE PHOTOPATCH TEST; ITS TECHNIQUE, MANIFESTATIONS, AND SIGNIFICANCE.
    Annals of allergy, 1964, Volume: 22

    Topics: Anti-Infective Agents, Local; Chlorpromazine; Coal Tar; Dermatitis, Contact; Drug Eruptions; Griseof

1964
PHOTODERMATITIS INDUCED BY DRUGS. I. CONTACT PHOTODERMATITIS.
    Skin, 1964, Volume: 3

    Topics: Chlorpromazine; Dermatitis; Dermatitis, Contact; Dermatitis, Phototoxic; Dermatology; Drug Eruptions

1964
OCULOCUTANEOUS CHANGES AFTER YEARS OF HIGH DOSES OF CHLORPROMAZINE.
    Lancet (London, England), 1965, Jan-30, Volume: 1, Issue:7379

    Topics: Chlorpromazine; Diagnosis; Drug Eruptions; Eye Diseases; Facial Dermatoses; Pathology; Pigmentation

1965
TOXIC EPIDERMAL NECROLYSIS.
    JAMA, 1965, Mar-22, Volume: 191

    Topics: Alcoholism; Anti-Bacterial Agents; Chloramphenicol; Chlorpromazine; Drug Eruptions; Drug Therapy; Hu

1965
BLOOD DYSCRASIAS ASSOCIATED WITH ANTITUBERCULOSIS AND/OR TRANQUILIZING CHEMOTHERAPY. A LONG-TERM CLINICAL OBSERVATION.
    Diseases of the chest, 1965, Volume: 47

    Topics: Aminosalicylic Acid; Aminosalicylic Acids; Antitubercular Agents; Chemical and Drug Induced Liver In

1965
[Dermatitis in patients under chlorpromazine therapy].
    Annales medico-psychologiques, 1955, Volume: 113 1, Issue:5

    Topics: Chlorpromazine; Drug Eruptions; Electroconvulsive Therapy; Mental Disorders; Psychosurgery; Psychoth

1955
[Bullous aminazin dermatitis].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1960, Volume: 60

    Topics: Chlorpromazine; Drug Eruptions; Humans; Skin Diseases, Vesiculobullous

1960
[Morphological changes in a bullo-necrotic form of aminazin toxicodermatitis].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1960, Volume: 60

    Topics: Chlorpromazine; Dermatitis; Drug Eruptions; Humans; Immune System Diseases; Necrosis

1960
[Severe medicamentous disease induced by aminazine and barbiturates].
    Sovetskaia meditsina, 1981, Issue:9

    Topics: Adult; Barbiturates; Chemical and Drug Induced Liver Injury; Chlorpromazine; Drug Eruptions; Epileps

1981
What syndrome is this? Nicolau syndrome.
    Pediatric dermatology, 1995, Volume: 12, Issue:2

    Topics: Child, Preschool; Chlorpromazine; Drug Eruptions; Erythema; Humans; Injections, Intramuscular; Leg U

1995
Pustular eruptions after chlorpromazine.
    BMJ (Clinical research ed.), 1994, Jul-09, Volume: 309, Issue:6947

    Topics: Adult; Chlorpromazine; Drug Eruptions; Female; Humans; Male; Middle Aged

1994
Cutaneous and ocular changes associated with the use of chlorpromazine.
    International journal of clinical pharmacology, therapy, and toxicology, 1993, Volume: 31, Issue:8

    Topics: Carcinoma, Basal Cell; Chlorpromazine; Drug Eruptions; Eye Diseases; Humans; Male; Middle Aged; Mout

1993
Phototoxic properties of neuroleptic drugs.
    Dermatology (Basel, Switzerland), 1997, Volume: 194, Issue:2

    Topics: Antipsychotic Agents; Chlorpromazine; Chlorprothixene; Clopenthixol; Dermatitis, Phototoxic; Drug Er

1997
Phenothiazine phototoxicity: toxic chlorpromazine photoproducts.
    The Journal of investigative dermatology, 1977, Volume: 69, Issue:4

    Topics: Animals; Candida albicans; Chlorpromazine; Drug Eruptions; Female; Guinea Pigs; Hydrogen-Ion Concent

1977
Chlorpromazine-induced histamine release from guinea-pig skin in vitro--a photosensitive reaction.
    Archives for dermatological research = Archiv fur dermatologische Forschung, 1976, Jun-21, Volume: 255, Issue:3

    Topics: Animals; Chlorpromazine; Drug Eruptions; Guinea Pigs; Histamine Release; Photosensitivity Disorders;

1976
Chlorpromazine photoallergy. Coexistence of immediate and delayed type.
    Archives of dermatology, 1975, Volume: 111, Issue:11

    Topics: Chlorpromazine; Dermatitis, Contact; Drug Eruptions; Drug Hypersensitivity; Female; Humans; Hypersen

1975
Immediate wheal after topical administration of chlorproethazine.
    Contact dermatitis, 1992, Volume: 26, Issue:4

    Topics: Administration, Topical; Chlorpromazine; Drug Eruptions; Humans; Hypersensitivity, Immediate; Male;

1992
Neuroleptic-induced skin pigmentation in chronic hospitalized schizophrenic patients.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1985, Volume: 30, Issue:6

    Topics: Adult; Age Factors; Antipsychotic Agents; Chlorpromazine; Drug Eruptions; Female; Humans; Male; Midd

1985
The significance of long wave UVL (320-400 nm; UVA) in light induced diseases.
    Acta dermato-venereologica, 1973, Volume: 53, Issue:5

    Topics: Adult; Aged; Anilides; Biopsy; Chlorothiazide; Chlorpromazine; Dermatitis, Contact; Drug Eruptions;

1973
[Ocular and cutaneous changes in patients exposed to prolonged treatment with neuroleptic drugs].
    Annali di ottalmologia e clinica oculistica, 1968, Volume: 94, Issue:7

    Topics: Adult; Aged; Chlorpromazine; Conjunctiva; Cornea; Drug Eruptions; Eye Diseases; Female; Humans; Lens

1968