chlorpromazine has been researched along with Dermatitis, Contact, Phototoxic in 17 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "By a photohemolysis test we assessed in vitro the phototoxic properties of 12 phenothiazines (chlorpromazine, dixyrazine, fluphenazine, levomepromazine, perazine, perphenazine, promazine, promethazine, prothipendyl, thioridazine, trifluoperazine, triflupromazine) and 5 thioxanthenes (chlorprothixene, clopenthixol, flupenthixol, thiothixene, zuclopenthixol)." | 3.69 | Phototoxic properties of neuroleptic drugs. ( Bindl, A; Eberlein-König, B; Przybilla, B, 1997) |
| "Chlorpromazine (CPZ) has been shown to exhibit photosensitivity and phototoxicity reaction in vitro and in vivo." | 1.37 | A comparative evaluation of photo-toxic effect of fractionated melanin and chlorpromazine hydrochloride on human (dermal fibroblasts and epidermal keratinocytes) and mouse cell line/s (fibroblast Balb/c 3T3). ( Dayan, N; Michniak-Kohn, B; Rai, V, 2011) |
| "Amiodarone was shown to have no effect on cellular glutathione levels, which suggests that an alternative mechanism of detoxification was occurring in this case." | 1.34 | An evaluation of the effects of photoactivation of bithionol, amiodarone and chlorpromazine on human keratinocytes in vitro. ( Clothier, RH; Khammo, N; Reid, L, 2007) |
| "In such conditions, the phototoxicity assay is much more sensitive, so that the model is expected to be of great interest for the detection not only of strong but also of weak phototoxic compounds." | 1.31 | Development of a highly sensitive in vitro phototoxicity assay using the SkinEthic reconstructed human epidermis. ( Barrault, C; Bernard, FX; De Wever, B; Deguercy, A; Rosdy, M, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (47.06) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 4 (23.53) | 29.6817 |
| 2010's | 3 (17.65) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maciel, B | 1 |
| Moreira, P | 1 |
| Carmo, H | 1 |
| Gonçalo, M | 1 |
| Lobo, JMS | 1 |
| Almeida, IF | 1 |
| Woods, JA | 1 |
| Ferguson, JS | 1 |
| Kalra, S | 1 |
| Degabriele, A | 1 |
| Gardner, J | 1 |
| Logan, P | 1 |
| Ferguson, J | 2 |
| Rai, V | 1 |
| Dayan, N | 1 |
| Michniak-Kohn, B | 1 |
| BLACKLEY, RJ | 2 |
| EPSTEIN, JH | 1 |
| BRUNSTING, LA | 1 |
| PETERSEN, MC | 1 |
| SCHWARZ, BE | 1 |
| CAFFEY, EM | 1 |
| LINDEMAN, JE | 1 |
| ROBERTS, AS | 1 |
| KINGSLEY, HJ | 1 |
| DICKEY, RF | 1 |
| HARTMAN, DL | 1 |
| HAYS, GB | 1 |
| LYLE, CB | 1 |
| WHEELER, CE | 1 |
| BAN, TA | 1 |
| LEHMANN, HE | 1 |
| GALLAI, Z | 1 |
| WARNES, H | 1 |
| LEE, H | 1 |
| SIDI, E | 1 |
| HINCKY, M | 1 |
| GERVAIS, A | 1 |
| Reid, L | 1 |
| Khammo, N | 1 |
| Clothier, RH | 1 |
| Kerr, A | 1 |
| Woods, J | 1 |
| Onoue, S | 1 |
| Kawamura, K | 1 |
| Igarashi, N | 1 |
| Zhou, Y | 1 |
| Fujikawa, M | 1 |
| Yamada, H | 1 |
| Tsuda, Y | 1 |
| Seto, Y | 1 |
| Yamada, S | 1 |
| Vohr, HW | 1 |
| Homey, B | 1 |
| Schuppe, HC | 1 |
| Kind, P | 1 |
| Eberlein-König, B | 1 |
| Bindl, A | 1 |
| Przybilla, B | 1 |
| Bernard, FX | 1 |
| Barrault, C | 1 |
| Deguercy, A | 1 |
| De Wever, B | 1 |
| Rosdy, M | 1 |
1 trial available for chlorpromazine and Dermatitis, Contact, Phototoxic
| Article | Year |
|---|---|
Photocontact allergic and phototoxic studies of chlorproethazine.
Topics: Cells, Cultured; Chlorpromazine; Dermatitis, Phototoxic; Female; Humans; Inhibitory Concentration 50 | 2008 |
16 other studies available for chlorpromazine and Dermatitis, Contact, Phototoxic
| Article | Year |
|---|---|
Implementation of an in vitro methodology for phototoxicity evaluation in a human keratinocyte cell line.
Topics: 5-Methoxypsoralen; Animal Testing Alternatives; Animals; Aspirin; Biological Assay; Cell Line; Chlor | 2019 |
The phototoxicity of vemurafenib: An investigation of clinical monochromator phototesting and in vitro phototoxicity testing.
Topics: Cell Line; Chlorpromazine; Chromatography, High Pressure Liquid; Dermatitis, Phototoxic; Dexamethaso | 2015 |
A comparative evaluation of photo-toxic effect of fractionated melanin and chlorpromazine hydrochloride on human (dermal fibroblasts and epidermal keratinocytes) and mouse cell line/s (fibroblast Balb/c 3T3).
Topics: Animals; BALB 3T3 Cells; Cell Line; Cell Survival; Chlorpromazine; Dermatitis, Phototoxic; Fibroblas | 2011 |
Disappearance of chlorpromazine-induced photosensitivity on substitution of promazine; report on eight cases.
Topics: Chlorpromazine; Dermatitis, Phototoxic; Humans; Phenothiazines; Photosensitivity Disorders; Promazin | 1957 |
Disappearance of chlorpromazine-induced photosensitivity on substitution of promazine; report on eight cases.
Topics: Chlorpromazine; Dermatitis, Phototoxic; Humans; Phenothiazines; Photosensitivity Disorders; Promazin | 1957 |
Disappearance of chlorpromazine-induced photosensitivity on substitution of promazine; report on eight cases.
Topics: Chlorpromazine; Dermatitis, Phototoxic; Humans; Phenothiazines; Photosensitivity Disorders; Promazin | 1957 |
Disappearance of chlorpromazine-induced photosensitivity on substitution of promazine; report on eight cases.
Topics: Chlorpromazine; Dermatitis, Phototoxic; Humans; Phenothiazines; Photosensitivity Disorders; Promazin | 1957 |
A study of photosensitivity occurring with chlorpromazine therapy.
Topics: Chlorpromazine; Dermatitis, Phototoxic; Humans; Light; Photosensitivity Disorders | 1957 |
Thorazine photosensitivity.
Topics: Chlorpromazine; Dermatitis, Phototoxic; Drug Eruptions; Humans; Medical Records; Photosensitivity Di | 1958 |
A case of photosensitivity occurring with largactil therapy.
Topics: Chlorpromazine; Dermatitis, Phototoxic; Humans; Photosensitivity Disorders | 1962 |
PHOTODERMATITIS INDUCED BY DRUGS. I. CONTACT PHOTODERMATITIS.
Topics: Chlorpromazine; Dermatitis; Dermatitis, Contact; Dermatitis, Phototoxic; Dermatology; Drug Eruptions | 1964 |
SLATE-GRAY COLOR IN PATIENTS RECEIVING CHLORPROMAZINE.
Topics: Argyria; Chlorpromazine; Chromatophores; Dermatitis, Phototoxic; Diagnosis, Differential; Drug Thera | 1964 |
[RELATION BETWEEN PHOTOSENSITIVITY AND PATHOLOGIC PIGMENTATION OF THE SKIN WITH HIGH DOSES OF CHLORPROMAZINE].
Topics: Chlorpromazine; Dermatitis, Phototoxic; Drug Therapy; Photosensitivity Disorders; Pigmentation; Pigm | 1965 |
Allergic sensitization and photosensitization to phenergan cream.
Topics: Anti-Allergic Agents; Chlorpromazine; Dermatitis, Phototoxic; Histamine H1 Antagonists; Humans; Hype | 1955 |
An evaluation of the effects of photoactivation of bithionol, amiodarone and chlorpromazine on human keratinocytes in vitro.
Topics: Amiodarone; Animal Testing Alternatives; Anti-Arrhythmia Agents; Anti-Infective Agents, Local; Antio | 2007 |
Reactive oxygen species assay-based risk assessment of drug-induced phototoxicity: classification criteria and application to drug candidates.
Topics: Animals; BALB 3T3 Cells; Benzophenones; Biological Assay; Chlorpromazine; Dermatitis, Phototoxic; Di | 2008 |
Detection of photoreactivity demonstrated in a modified local lymph node assay in mice.
Topics: Allergens; Animals; Chlorpromazine; Dermatitis, Photoallergic; Dermatitis, Phototoxic; Dinitrofluoro | 1994 |
Phototoxic properties of neuroleptic drugs.
Topics: Antipsychotic Agents; Chlorpromazine; Chlorprothixene; Clopenthixol; Dermatitis, Phototoxic; Drug Er | 1997 |
Development of a highly sensitive in vitro phototoxicity assay using the SkinEthic reconstructed human epidermis.
Topics: 4-Aminobenzoic Acid; 5-Methoxypsoralen; Adult; Antipruritics; Benzophenones; Chlorpromazine; Colorin | 2000 |