chlorpromazine has been researched along with Depressive Disorder, Major in 28 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Depressive Disorder, Major: Disorder in which five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure. Symptoms include: depressed mood most of the day, nearly every daily; markedly diminished interest or pleasure in activities most of the day, nearly every day; significant weight loss when not dieting or weight gain; Insomnia or hypersomnia nearly every day; psychomotor agitation or retardation nearly every day; fatigue or loss of energy nearly every day; feelings of worthlessness or excessive or inappropriate guilt; diminished ability to think or concentrate, or indecisiveness, nearly every day; or recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt. (DSM-5)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eight cases of glossodynia arising in the context of an endogenous depression are reported and the case histories of four of them are presented." | 1.27 | [Vital disorders of the mouth (glossodynia) in depressive involutional psychoses]. ( Maier, C, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (85.71) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (7.14) | 29.6817 |
| 2010's | 2 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jiang, MD | 1 |
| Zheng, Y | 1 |
| Wang, JL | 1 |
| Wang, YF | 1 |
| Udawela, M | 1 |
| Money, TT | 1 |
| Neo, J | 1 |
| Seo, MS | 1 |
| Scarr, E | 1 |
| Dean, B | 1 |
| Everall, IP | 1 |
| Addington, J | 1 |
| Leriger, E | 1 |
| Addington, D | 1 |
| MORGAN, DR | 1 |
| UMANSKAIA, RM | 1 |
| ALNAES, R | 1 |
| KRISTIANSEN, J | 1 |
| BUIS, C | 1 |
| FLOHIL, JM | 1 |
| POELDINGER, W | 1 |
| MARINOW, A | 1 |
| STRAKHOV, AP | 1 |
| GONZALEZ, JR | 1 |
| IMAHARA, JK | 1 |
| SMITH, ME | 1 |
| CHASSAN, JB | 1 |
| Matsumoto, M | 1 |
| Konno, T | 1 |
| Tamba, K | 1 |
| Abe, T | 1 |
| Kato, S | 1 |
| Kajii, E | 1 |
| Neduva, SSh | 1 |
| Brion, S | 1 |
| Chevalier, JF | 1 |
| Guerin, R | 1 |
| Ginestet, D | 1 |
| Kamen, S | 1 |
| Singer, L | 1 |
| Finance, MF | 1 |
| Ruh, MD | 1 |
| Maier, C | 1 |
| Fracchia, J | 1 |
| Sheppard, C | 1 |
| Merlis, S | 1 |
| Whitehead, JA | 1 |
| Chohan, MM | 1 |
| Gol'dovskaia, IL | 1 |
| Il'in, II | 1 |
| Dziubenko, MS | 1 |
| Bargman, BB | 1 |
| Klein, DF | 1 |
| Radzuweit, H | 1 |
| Knorr, W | 1 |
| Lichko, AE | 1 |
| Braverman, LB | 1 |
| Henderson, JG | 1 |
| Dawson, AA | 1 |
| Rosenblatt, S | 1 |
| Chanley, JD | 1 |
| Hrushka, M | 1 |
| Bruck, M | 1 |
| Hsu, JJ | 1 |
3 trials available for chlorpromazine and Depressive Disorder, Major
| Article | Year |
|---|---|
Combination medications in psychiatric treatment: patterns in a group of elderly hospital patients.
Topics: Age Factors; Aged; Amitriptyline; Antidepressive Agents; Antihypertensive Agents; Antisocial Persona | 1971 |
[Sympathetic-adrenal complex in man under prolonged (several hours) action of aminazin].
Topics: Chlorpromazine; Clinical Trials as Topic; Depressive Disorder, Major; Drug Synergism; Epinephrine; H | 1965 |
Chlorpromazine-procyclidine combination, imipramine and placebo in depressive disorders.
Topics: Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Depressive Disorder, Major; Humans; Imip | 1966 |
25 other studies available for chlorpromazine and Depressive Disorder, Major
| Article | Year |
|---|---|
Drug induces depression-like phenotypes and alters gene expression profiles in Drosophila.
Topics: Animals; Chlorpromazine; Depressive Disorder, Major; Disease Models, Animal; Dose-Response Relations | 2017 |
SELENBP1 expression in the prefrontal cortex of subjects with schizophrenia.
Topics: Animals; Antipsychotic Agents; Bipolar Disorder; Case-Control Studies; Chlorpromazine; Depressive Di | 2015 |
Symptom outcome 1 year after admission to an early psychosis program.
Topics: Adult; Antipsychotic Agents; Chlorpromazine; Depressive Disorder, Major; Diagnostic and Statistical | 2003 |
Largactil, ritalin and meratran in the treatment of endogenous psychotic depression.
Topics: Bipolar Disorder; Chlorpromazine; Depression; Depressive Disorder, Major; Methylphenidate; Piperidin | 1957 |
[On the results of aminazin therapy of patients with presenile psychoses].
Topics: Alzheimer Disease; Chlorpromazine; Depressive Disorder, Major; Mental Disorders; Psychotic Disorders | 1960 |
[DESMETHYLIMIPRAMINE (PERTOFRAN) IN THE TREATMENT OF DEPRESSIONS. A CLINICAL AND PSYCHODYNAMIC APPRAISAL].
Topics: Antidepressive Agents; Biomedical Research; Bipolar Disorder; Chlorpromazine; Depression; Depressive | 1963 |
[CLINICAL EXPERIENCES WITH HALOPERIDOL (SERENASE)].
Topics: Bipolar Disorder; Chlorpromazine; Chorea; Dementia; Depressive Disorder, Major; Epilepsy; Haloperido | 1964 |
[LAROXYL (AMITRIPTYLINE), A THYMOLEPTIC WITH A NEUROLEPTIC EFFICACY COMPONENT].
Topics: Amitriptyline; Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Chlordiazepoxide; Chlo | 1963 |
[TREATMENT OF DEPRESSION WITH TOFRANIL WITH REGARD TO THE DRAWING TEST].
Topics: Bipolar Disorder; Chlorpromazine; Depression; Depressive Disorder; Depressive Disorder, Major; Human | 1964 |
[PECULIARITIES OF THE PHOTOERYTHEMIC SKIN REACTION IN PATIENTS WITH MANIC-DEPRESSIVE CONDITIONS AND ITS DYNAMICS DURING THE COURSE OF TREATMENT].
Topics: Anxiety; Anxiety Disorders; Bipolar Disorder; Chlorpromazine; Depression; Depressive Disorder; Depre | 1963 |
ELECTROSHOCK THERAPY WITH THE PHENOTHIAZINES AND RESERPINE: A SURVEY AND REPORT.
Topics: Adolescent; Bipolar Disorder; Black People; Chlorpromazine; Depressive Disorder, Major; Drug Therapy | 1964 |
COMPARISONS OF DIAZEPAM, CHLORPROMAZINE AND TRIFLUOPERAZINE IN A DOUBLE-BLIND CLINICAL INVESTIGATION.
Topics: Anxiety; Anxiety Disorders; Biomedical Research; Chlorpromazine; Depression; Depressive Disorder; De | 1964 |
Two cases of deep vein thrombosis associated with antipsychotic drug use.
Topics: Aged; Antipsychotic Agents; Chlorpromazine; Depressive Disorder, Major; Dose-Response Relationship, | 2004 |
[On the topography and dynamics of skin potentials under normal conditions and in some diseases of the central nervous system (schizophrenia and epilepsy)].
Topics: Chlorpromazine; Depressive Disorder, Major; Electroencephalography; Electrophysiology; Epilepsy; Hum | 1966 |
[Chemotherapy of melancholia by sequential neuroleptic-viloxazine association].
Topics: Adjustment Disorders; Adult; Bipolar Disorder; Chlorpromazine; Depression; Depressive Disorder, Majo | 1976 |
Tardive dyskinesia. A significant syndrome for geriatric dentistry.
Topics: Aged; Arteriosclerosis; Bruxism; Chlorpromazine; Dementia; Denture, Complete; Depression; Depressive | 1975 |
[Pulmonary embolisms occurring in 1 month in 3 aged women with manic-depressive psychoses. Discussion. Etiopathogenic role or psychiatric treatment].
Topics: Aged; Antidepressive Agents; Bipolar Disorder; Chlorpromazine; Clomipramine; Depressive Disorder, Ma | 1975 |
[Vital disorders of the mouth (glossodynia) in depressive involutional psychoses].
Topics: Aged; Amitriptyline; Chlorpromazine; Depressive Disorder, Major; Drug Therapy, Combination; Female; | 1986 |
Paraphrenia and pernicious anemia.
Topics: Adult; Aged; Anemia, Pernicious; Bone Marrow Examination; Chlorpromazine; Depressive Disorder, Major | 1972 |
[Ophthalmologic study of patients receiving psychotropic drugs].
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents; Bipolar Disorder; Cataract; Cerebrova | 1970 |
[Influencing of biological and immunologic pregnancy reactions by psychotropic drugs].
Topics: Adolescent; Adult; Aged; Butyrophenones; Chlorpromazine; Dementia; Depressive Disorder, Major; Dysau | 1969 |
[Protracted (unaffected by glucose) insulin comas, their cause, clinical picture and treatment].
Topics: Amobarbital; Barbiturates; Chlorpromazine; Convulsive Therapy; Depressive Disorder, Major; Encephali | 1970 |
Serum vitamin-B12 levels in psychiatric patients on long-term psychotropic drug therapy.
Topics: Adult; Aged; Biological Assay; Bipolar Disorder; Chlorpromazine; Depressive Disorder, Major; Female; | 1970 |
The metabolism of norepinephrine in depressions. Differences and effects of therapies.
Topics: Adult; Aged; Amitriptyline; Bipolar Disorder; Chlordiazepoxide; Chlorpromazine; Depression; Depressi | 1966 |
Therapeutic effects of different modes of chlorpromazine administration.
Topics: Bipolar Disorder; Brain Damage, Chronic; Chlorpromazine; Depressive Disorder, Major; Female; Humans; | 1966 |