chlorpromazine has been researched along with Delirium in 29 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Delirium: A disorder characterized by CONFUSION; inattentiveness; disorientation; ILLUSIONS; HALLUCINATIONS; agitation; and in some instances autonomic nervous system overactivity. It may result from toxic/metabolic conditions or structural brain lesions. (From Adams et al., Principles of Neurology, 6th ed, pp411-2)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to examine the efficacy and side effects of haloperidol, chlorpromazine, and lorazepam for the treatment of the symptoms of delirium in adult AIDS patients in a randomized, double-blind, comparison trial." | 9.08 | A double-blind trial of haloperidol, chlorpromazine, and lorazepam in the treatment of delirium in hospitalized AIDS patients. ( Breitbart, W; Corbera, K; Derevenco, M; Grau, C; Jacobson, P; Lund, S; Marotta, R; Platt, MM; Raymond, S; Weisman, H, 1996) |
| "To investigate factors affecting the effectiveness and safety of intravenous chlorpromazine for irreversible delirium in patients with terminal cancer." | 7.88 | Factors Associated with the Effectiveness of Intravenous Administration of Chlorpromazine for Delirium in Patients with Terminal Cancer. ( Fujii, R; Fukunaga, M; Hasuo, H; Kanbara, K; Sakuma, H; Uchitani, K, 2018) |
| "The purpose of this study was to examine the efficacy and side effects of haloperidol, chlorpromazine, and lorazepam for the treatment of the symptoms of delirium in adult AIDS patients in a randomized, double-blind, comparison trial." | 5.08 | A double-blind trial of haloperidol, chlorpromazine, and lorazepam in the treatment of delirium in hospitalized AIDS patients. ( Breitbart, W; Corbera, K; Derevenco, M; Grau, C; Jacobson, P; Lund, S; Marotta, R; Platt, MM; Raymond, S; Weisman, H, 1996) |
| "The data from one study of 30 patients would perhaps suggest that haloperidol is the most suitable drug therapy for the treatment of patients with delirium near the end of life." | 4.82 | Drug therapy for delirium in terminally ill patients. ( Jackson, KC; Lipman, AG, 2004) |
| "To investigate factors affecting the effectiveness and safety of intravenous chlorpromazine for irreversible delirium in patients with terminal cancer." | 3.88 | Factors Associated with the Effectiveness of Intravenous Administration of Chlorpromazine for Delirium in Patients with Terminal Cancer. ( Fujii, R; Fukunaga, M; Hasuo, H; Kanbara, K; Sakuma, H; Uchitani, K, 2018) |
| "The authors describe a woman with chronic schizophrenia who experienced delirium, grand mal seizure, and photosensitivity after the addition of propranolol to her neuroleptic regimen." | 3.66 | Adverse effects of combined propranolol and chlorpromazine therapy. ( Miller, FA; Rampling, D, 1982) |
| "Delirium is a syndrome characterised by an acute disturbance of attention and awareness which develops over a short time period and fluctuates in severity over the course of the day." | 2.66 | Drug therapy for delirium in terminally ill adults. ( Candy, B; Finucane, AM; Jones, L; Leurent, B; Sampson, EL; Stone, P; Tookman, A, 2020) |
| "Delirium is a syndrome characterised by a disturbance of consciousness (often fluctuating), cognition and perception." | 2.48 | Drug therapy for delirium in terminally ill adult patients. ( Candy, B; Jackson, KC; Jones, L; King, M; Leurent, B; Tookman, A, 2012) |
| " This study aims to investigate whether different dosing patterns of antipsychotics (single or multiple administrations) influence the outcomes of delirium treatment." | 1.91 | Influence of dosing pattern of antipsychotics on treatment outcome of delirium in patients with advanced cancer. ( Abe, A; Fujisawa, D; Imai, K; Iwase, S; Maeda, I; Matsuda, Y; Matsuo, N; Mimura, M; Miyajima, K; Ogawa, A; Takeuchi, E; Takeuchi, M; Uemura, K; Watanabe, H; Yoshiuchi, K, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (72.41) | 18.7374 |
| 1990's | 1 (3.45) | 18.2507 |
| 2000's | 1 (3.45) | 29.6817 |
| 2010's | 4 (13.79) | 24.3611 |
| 2020's | 2 (6.90) | 2.80 |
| Authors | Studies |
|---|---|
| Abe, A | 1 |
| Fujisawa, D | 1 |
| Miyajima, K | 1 |
| Takeuchi, E | 1 |
| Takeuchi, M | 1 |
| Mimura, M | 1 |
| Imai, K | 1 |
| Uemura, K | 1 |
| Watanabe, H | 1 |
| Matsuo, N | 1 |
| Matsuda, Y | 1 |
| Maeda, I | 1 |
| Ogawa, A | 1 |
| Yoshiuchi, K | 1 |
| Iwase, S | 1 |
| Finucane, AM | 1 |
| Jones, L | 2 |
| Leurent, B | 2 |
| Sampson, EL | 1 |
| Stone, P | 1 |
| Tookman, A | 2 |
| Candy, B | 2 |
| Hasuo, H | 1 |
| Kanbara, K | 1 |
| Fujii, R | 1 |
| Uchitani, K | 1 |
| Sakuma, H | 1 |
| Fukunaga, M | 1 |
| Abengaña, J | 1 |
| Chong, MS | 1 |
| Tay, L | 1 |
| Kashyap, GL | 1 |
| Patel, AG | 1 |
| Jackson, KC | 2 |
| King, M | 1 |
| DE BURES, I | 2 |
| DURAND, VJ | 2 |
| HENNE, M | 2 |
| DEMAY, J | 2 |
| LETAILLEUR, M | 2 |
| MONNERIE, R | 2 |
| MORIN, J | 2 |
| BARNAUD, J | 2 |
| BERTHIER, C | 2 |
| BONNERU-COUCHOUD, M | 2 |
| BASAGLIA, F | 1 |
| AYCRIGG, JB | 1 |
| STROEMGREN, E | 1 |
| VOLMAT, R | 1 |
| BEAUDOUIN, JL | 1 |
| COLLIN, J | 1 |
| NICOLAS-CHARLES, PJ | 1 |
| ALLERS, G | 1 |
| BLACHY, PH | 1 |
| STARR, A | 1 |
| Lipman, AG | 1 |
| Miller, FA | 1 |
| Rampling, D | 1 |
| Breitbart, W | 1 |
| Marotta, R | 1 |
| Platt, MM | 1 |
| Weisman, H | 1 |
| Derevenco, M | 1 |
| Grau, C | 1 |
| Corbera, K | 1 |
| Raymond, S | 1 |
| Lund, S | 1 |
| Jacobson, P | 1 |
| Hollender, MH | 1 |
| Jamieson, RC | 1 |
| McKee, EA | 1 |
| Roback, HB | 1 |
| Wise, TN | 1 |
| Ginzler, EM | 1 |
| Evans, JI | 1 |
| Lewis, SA | 1 |
| Kornfeld, DS | 2 |
| Ioffe, AV | 1 |
| de Barros-Ferreira, M | 1 |
| Mattos, E | 1 |
| Morozova, TV | 1 |
| Sprints, AM | 1 |
| Shenderov, BL | 1 |
| Mamtseva, VN | 1 |
| Semenovskaia, EI | 1 |
| Gunning, JF | 1 |
| Shanahan, MX | 1 |
| Windsor, HM | 1 |
| Itil, T | 1 |
| Fink, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Open-label Randomized Controlled Trial of Oral Transmucosal Haloperidol and Olanzapine in the Treatment of Terminal Delirium[NCT04750395] | Phase 2 | 80 participants (Anticipated) | Interventional | 2021-09-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for chlorpromazine and Delirium
| Article | Year |
|---|---|
Drug therapy for delirium in terminally ill adults.
Topics: Adult; Antipsychotic Agents; Chlorpromazine; Delirium; Haloperidol; Humans; Lorazepam; Randomized Co | 2020 |
Drug therapy for delirium in terminally ill adult patients.
Topics: Adult; Antipsychotic Agents; Chlorpromazine; Delirium; Haloperidol; Humans; Lorazepam; Randomized Co | 2012 |
Drug therapy for delirium in terminally ill patients.
Topics: Antipsychotic Agents; Chlorpromazine; Delirium; Haloperidol; Humans; Lorazepam; Terminally Ill | 2004 |
Psychiatric complications of cardiac surgery.
Topics: Adaptation, Psychological; Adult; Cardiac Surgical Procedures; Chlorpromazine; Conflict, Psychologic | 1967 |
1 trial available for chlorpromazine and Delirium
| Article | Year |
|---|---|
A double-blind trial of haloperidol, chlorpromazine, and lorazepam in the treatment of delirium in hospitalized AIDS patients.
Topics: Adult; AIDS Dementia Complex; Basal Ganglia Diseases; Chlorpromazine; Delirium; Double-Blind Method; | 1996 |
24 other studies available for chlorpromazine and Delirium
| Article | Year |
|---|---|
Influence of dosing pattern of antipsychotics on treatment outcome of delirium in patients with advanced cancer.
Topics: Antipsychotic Agents; Chlorpromazine; Delirium; Female; Humans; Male; Neoplasms; Treatment Outcome | 2023 |
Factors Associated with the Effectiveness of Intravenous Administration of Chlorpromazine for Delirium in Patients with Terminal Cancer.
Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Chlorpromazine; D | 2018 |
Delirium superimposed on dementia: phenomenological differences between patients with and without behavioral and psychological symptoms of dementia in a specialized delirium unit.
Topics: Aged; Aged, 80 and over; Chlorpromazine; Delirium; Dementia; Female; Humans; Length of Stay; Linear | 2017 |
Unusual presentation of a patient with GBL withdrawal: a case report.
Topics: 4-Butyrolactone; Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Chlorpromazine; Delirium; Hal | 2011 |
[Serious delirious syndrome of paranoid aspect of three years' duration, disappearing after three weeks of chlorpromazine per os; critical written analysis by the patient].
Topics: Chlorpromazine; Delirium; Humans; Paranoid Disorders; Syndrome; Writing | 1956 |
[Serious delirious syndrome of paranoid aspect of three years' duration, disappearing after three weeks of chlorpromazine per os; critical written analysis by the patient].
Topics: Chlorpromazine; Delirium; Humans; Paranoid Disorders; Syndrome; Writing | 1956 |
[Serious delirious syndrome of paranoid aspect of three years' duration, disappearing after three weeks of chlorpromazine per os; critical written analysis by the patient].
Topics: Chlorpromazine; Delirium; Humans; Paranoid Disorders; Syndrome; Writing | 1956 |
[Serious delirious syndrome of paranoid aspect of three years' duration, disappearing after three weeks of chlorpromazine per os; critical written analysis by the patient].
Topics: Chlorpromazine; Delirium; Humans; Paranoid Disorders; Syndrome; Writing | 1956 |
[Chlorpromazine in the treatment of acute and subacute delirium tremens].
Topics: Alcohol Withdrawal Delirium; Chlorpromazine; Delirium; Humans; Mental Disorders; Psychoses, Alcoholi | 1956 |
[Chlorpromazine in the treatment of acute and subacute delirium tremens].
Topics: Alcohol Withdrawal Delirium; Chlorpromazine; Delirium; Humans; Mental Disorders; Psychoses, Alcoholi | 1956 |
[Chlorpromazine in the treatment of acute and subacute delirium tremens].
Topics: Alcohol Withdrawal Delirium; Chlorpromazine; Delirium; Humans; Mental Disorders; Psychoses, Alcoholi | 1956 |
[Chlorpromazine in the treatment of acute and subacute delirium tremens].
Topics: Alcohol Withdrawal Delirium; Chlorpromazine; Delirium; Humans; Mental Disorders; Psychoses, Alcoholi | 1956 |
[Treatment of subacute and chronic alcoholic delirium].
Topics: Chlorpromazine; Delirium; Humans; Mental Disorders; Psychoses, Alcoholic; Psychotic Disorders; Vitam | 1956 |
[Treatment of subacute and chronic alcoholic delirium].
Topics: Chlorpromazine; Delirium; Humans; Mental Disorders; Psychoses, Alcoholic; Psychotic Disorders; Vitam | 1956 |
[Treatment of subacute and chronic alcoholic delirium].
Topics: Chlorpromazine; Delirium; Humans; Mental Disorders; Psychoses, Alcoholic; Psychotic Disorders; Vitam | 1956 |
[Treatment of subacute and chronic alcoholic delirium].
Topics: Chlorpromazine; Delirium; Humans; Mental Disorders; Psychoses, Alcoholic; Psychotic Disorders; Vitam | 1956 |
[The effects of chlorpromazine on a state of primary delirium].
Topics: Chlorpromazine; Delirium; Humans | 1957 |
TWO CASES OF WITHDRAWAL FROM ETHCHLORVYNOL.
Topics: Chlorpromazine; Delirium; Epilepsy, Tonic-Clonic; Ethchlorvynol; Hallucinations; Hypnotics and Sedat | 1964 |
PSYCHOSES CAUSED BY NEUROLEPTICS.
Topics: Antipsychotic Agents; Chlorpromazine; Delirium; Depression; Geriatrics; Humans; Mental Disorders; Ps | 1964 |
[COGENTINE (BTMS) IN THE TREATMENT OF NEUROLEPTIC SYNDROMES].
Topics: Antipsychotic Agents; Bipolar Disorder; Chlorpromazine; Delirium; Depression; Hallucinations; Halope | 1964 |
POST-CARDIOTOMY DELIRUM.
Topics: Blood Group Antigens; Cardiac Surgical Procedures; Chlorpromazine; Delirium; Drug Therapy; Electroen | 1964 |
Adverse effects of combined propranolol and chlorpromazine therapy.
Topics: Adult; Chlorpromazine; Delirium; Drug Therapy, Combination; Epilepsy, Tonic-Clonic; Female; Humans; | 1982 |
Anticholinergic delirium in a case of Munchausen syndrome.
Topics: Adult; Amitriptyline; Chlorpromazine; Delirium; Female; Humans; Munchausen Syndrome; Ophthalmic Solu | 1978 |
Scleroderma cerebritis, an unusual manifestation of progressive systemic sclerosis.
Topics: Adult; Cerebral Hemorrhage; Chlorpromazine; Delirium; Delusions; Electroencephalography; Female; Hal | 1975 |
Sleep studies in early delirium and during drug withdrawal in normal subjects and the effect of phenothiazines on such states.
Topics: Amobarbital; Chlorpromazine; Delirium; Humans; Phenothiazines; Sleep, REM; Substance Withdrawal Synd | 1968 |
[Peculiarities of neuropsychiatric disorders in children and adolescents in relation to the stage and severity of the course of typhoid-paratyphoid infection].
Topics: Adolescent; Child; Child, Preschool; Chlorpromazine; Delirium; Humans; Mental Disorders; Neurologic | 1968 |
[Developmental study on night sleep during episodes of manias or acute depressions].
Topics: Acute Disease; Adult; Bipolar Disorder; Chlorpromazine; Delirium; Electroencephalography; Female; Ha | 1969 |
[Spatial synchronization of alpha-activity in the cerebral cortex in patients with psychoses in advanced age].
Topics: Aged; Cerebral Cortex; Cerebrovascular Disorders; Chlorpromazine; Delirium; Dementia; Electroencepha | 1967 |
[On psychoses caused by asthmatol].
Topics: Adolescent; Adult; Affect; Amobarbital; Asthma; Atropa belladonna; Bronchodilator Agents; Chlorproma | 1968 |
[Toxic delirium among children with neuropsychiatric diseases during treatment with neuroleptics].
Topics: Adolescent; Age Factors; Child; Chlorpromazine; Delirium; Humans; Mental Disorders; Psychoses, Subst | 1968 |
Psychiatric view of the intensive care unit.
Topics: Anxiety; Chlorpromazine; Delirium; Environment; Heart Diseases; Humans; Intensive Care Units; Nurse- | 1969 |
Use of isoprenaline as an antiarrhythmic agent after valve replacement surgery.
Topics: Anti-Arrhythmia Agents; Chlorpromazine; Delirium; Female; Heart Valve Diseases; Heart Valve Prosthes | 1969 |
Anticholinergic drug-induced delirium: experimental modification, quantitative EEG and behavioral correlations.
Topics: Acridines; Adult; Behavior; Cerebral Cortex; Chlorpromazine; Delirium; Drug Antagonism; Electrocardi | 1966 |