chlorpromazine has been researched along with Decerebrate Posturing in 38 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "No protection against drug-induced arrhythmia or death was afforded by this procedure." | 5.27 | Does chlorpromazine produce cardiac arrhythmia via the central nervous system? ( Lathers, CM; Lipka, LJ; Roberts, J, 1988) |
| "No protection against drug-induced arrhythmia or death was afforded by this procedure." | 1.27 | Does chlorpromazine produce cardiac arrhythmia via the central nervous system? ( Lathers, CM; Lipka, LJ; Roberts, J, 1988) |
| "These results suggest that RF decerebrate rigidity can be used instead of intercollicular transection rigidity in the pharmacological and physiological studies." | 1.27 | Rigidity in rats due to radio frequency decerebration and effects of chlorpromazine and mephenesin. ( Fukuda, H; Ito, H; Nakamura, T; Oka, J; Ono, H, 1987) |
| " The compound exhibiting the greatest separation between the dosage that reduced rigidity and that which caused sedation was (Z)-2-propionyl-9-[3-(dimethylamino)propylidene]thioxanthene." | 1.26 | Acylthioxanthenes: agents which selectively reduce decerebrate rigidity in the cat. ( Ashton, MJ; Chapman, RF; Loveless, AH, 1980) |
| "Chlorpromazine that depresses decerebrate rigidity in a dose-related fashion requires 1." | 1.26 | Suppression of decerebrate rigidity by phenytoin and chlorpromazine. ( Anderson, RJ; Raines, A, 1976) |
| "It is likely that these drugs reduce decerebrate rigidity by inhibiting fusimotor activity." | 1.25 | A comparison of the actions of some drugs on decerebrate rigidity, muscle spindle activity and alpha-adrenoceptors. ( Maxwell, DR; Sumpter, EA, 1974) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 37 (97.37) | 18.7374 |
| 1990's | 1 (2.63) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ashton, MJ | 1 |
| Chapman, RF | 1 |
| Loveless, AH | 1 |
| VARMA, DR | 1 |
| BENFEY, BG | 1 |
| KORNEVA, EA | 1 |
| IAKOVLEVA, MI | 1 |
| FELLER, K | 1 |
| STAIB, AH | 1 |
| DECIMA, EE | 1 |
| HASLETT, WL | 1 |
| SCHALLEK, W | 1 |
| ZABRANSKY, F | 1 |
| KUEHN, A | 1 |
| Herman, EH | 1 |
| Barnes, CD | 2 |
| Keary, EM | 1 |
| Maxwell, DR | 4 |
| Hershkowitz, N | 1 |
| Mahany, TM | 1 |
| Raines, A | 2 |
| Strahlendorf, JC | 1 |
| Strahlendorf, HK | 1 |
| Kingsley, RE | 1 |
| Gintautas, J | 1 |
| Ito, T | 2 |
| Hori, M | 1 |
| Yoshida, K | 1 |
| Shimizu, M | 1 |
| Matsushita, M | 1 |
| Yonemori, F | 1 |
| Furukawa, N | 1 |
| Ohta, A | 1 |
| Toide, K | 1 |
| Uchida, I | 1 |
| Iwata, K | 1 |
| Anderson, RJ | 1 |
| Hudson, RD | 1 |
| Key, BJ | 1 |
| Krzywosinski, L | 1 |
| Share, NN | 1 |
| McFarlane, CS | 1 |
| Lipka, LJ | 1 |
| Lathers, CM | 1 |
| Roberts, J | 1 |
| Ono, H | 2 |
| Nakamura, T | 2 |
| Ito, H | 1 |
| Oka, J | 2 |
| Fukuda, H | 3 |
| Hagiwara, Y | 1 |
| Suzuki, Y | 1 |
| Matsumoto, K | 1 |
| Kato, K | 1 |
| Kato, F | 1 |
| Miyamoto, M | 1 |
| Mori, T | 1 |
| Read, MA | 2 |
| Sumpter, EA | 2 |
| Polc, P | 1 |
| Möhler, H | 1 |
| Haefely, W | 1 |
| Kadzielawa, K | 2 |
| Widy-Tyszkiewicz, E | 1 |
| Boyd, ES | 1 |
| Boyd, EH | 1 |
| Brown, LE | 1 |
| Ellaway, PH | 1 |
| Pascoe, JE | 2 |
| Schomburg, ED | 1 |
| Hashimoto, S | 1 |
| Kudo, Y | 1 |
| Ginzel, KH | 2 |
| Rosenstein, R | 1 |
| Matsushita, A | 1 |
| Smith, CM | 1 |
| Connor, JD | 1 |
| Clark, R | 1 |
| Lynes, TE | 1 |
| Price, WA | 1 |
| Smith, DH | 1 |
| Woodward, JK | 1 |
| Marvel, JP | 1 |
| Vernier, VG | 1 |
| Kimison, R | 1 |
| Thuránszky, K | 1 |
38 other studies available for chlorpromazine and Decerebrate Posturing
| Article | Year |
|---|---|
Acylthioxanthenes: agents which selectively reduce decerebrate rigidity in the cat.
Topics: Administration, Oral; Animals; Cats; Decerebrate State; Infusions, Parenteral; Isomerism; Mice; Moto | 1980 |
ANTAGONISM OF RESERPINE-INDUCED SUBSENSITIVITY TO TYRAMINE BY METHYLDOPA.
Topics: Antihypertensive Agents; Bretylium Compounds; Cats; Chlorpromazine; Decerebrate State; Guanethidine; | 1963 |
[SOME DATA ON THE ROLE OF THE HIGHER SEGMENTS OF THE BRAIN IN THE REACTION OF RESPIRATION TO AMINAZIN ADMINISTRATION].
Topics: Animals; Apnea; Brain; Cats; Central Nervous System; Cerebral Cortex; Chlorpromazine; Decerebrate St | 1963 |
[INVESTIGATIONS CONCERNING THE BRADYCARDIA INDUCED BY CHLORPROMAZINE].
Topics: Acetates; Adrenalectomy; Animals; Atropine; Bis-Trimethylammonium Compounds; Bradycardia; Carotid Si | 1964 |
EFFECTS OF OXOTREMORINE ON GAMMA FIBER ACTIVITY.
Topics: Cats; Central Nervous System; Chlorpromazine; Decerebrate State; Muscles; Neurophysiology; Oxotremor | 1964 |
EFFECTS OF BENZODIAZEPINES ON CENTRAL NERVOUS SYSTEM OF CAT.
Topics: Anticonvulsants; Benzodiazepines; Brain; Carbamates; Carisoprodol; Cats; Cerebral Cortex; Chlordiaze | 1964 |
Observations of drug effects on a type of spinal motor activity.
Topics: Animals; Atropine; Chlorpromazine; Decerebrate State; Motor Neurons; Muscles; Pentobarbital; Phenoxy | 1967 |
A comparison of the effects of chlorpromazine and some related phenothiazines in reducing the rigidity of the decerebrate cat and in some other central actions.
Topics: Animals; Barbiturates; Blood Pressure; Cats; Chlordiazepoxide; Chlorpromazine; Decerebrate State; El | 1967 |
Effects of carbamazepine on muscle tone in the decerebrate cat.
Topics: Animals; Carbamazepine; Cats; Chlorpromazine; Decerebrate State; Electric Stimulation; Female; Male; | 1983 |
Facilitation of the lumbar monosynaptic reflexes by locus coeruleus stimulation.
Topics: Animals; Blood Pressure; Cats; Chlorpromazine; Decerebrate State; Electric Stimulation; Female; Halo | 1980 |
Facilitation of tungstic acid gel-induced cortical epilepsy in rats by depression of the reticular formation.
Topics: Acids; Animals; Anticonvulsants; Biperiden; Chlorpromazine; Convulsants; Decerebrate State; Drug Int | 1980 |
Effects of the novel thyrotropin-releasing hormone analogue Na -((1S,2R)-2-methyl-4-oxocyclopentylcarbonyl)-L-histidyl-L-prol ina mide monohydrate on the central nervous system in mice and rats.
Topics: Animals; Body Temperature; Brain Concussion; Central Nervous System; Chlorpromazine; Consciousness; | 1993 |
Suppression of decerebrate rigidity by phenytoin and chlorpromazine.
Topics: Animals; Cats; Chlorpromazine; Decerebrate State; Disease Models, Animal; Dose-Response Relationship | 1976 |
Central nervous system responses to cigarette smoke inhalation in the cat.
Topics: Action Potentials; Animals; Blood Pressure; Cats; Central Nervous System; Chlorpromazine; Decerebrat | 1979 |
Comparison of the electrocortical changes induced by (+)-amphetamine and chlorpromazine when perfused directly into the dorsal raphé nucleus of the cat.
Topics: Animals; Cats; Chlorpromazine; Decerebrate State; Desipramine; Dextroamphetamine; Drug Interactions; | 1978 |
Cyclobenzaprine: novel centrally acting skeletal muscle relaxant.
Topics: Amitriptyline; Animals; Anticonvulsants; Ataxia; Cats; Chlorpromazine; Decerebrate State; Diazepam; | 1975 |
Does chlorpromazine produce cardiac arrhythmia via the central nervous system?
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Cats; Central Nervous System; Chlorpromazine; Decereb | 1988 |
Rigidity in rats due to radio frequency decerebration and effects of chlorpromazine and mephenesin.
Topics: Animals; Chlorpromazine; Decerebrate State; Male; Mephenesin; Muscle Rigidity; Radio Waves; Rats; Ra | 1987 |
Studies of chlorpromazine-induced enhancement of the potentials evoked by peripheral stimulation of the cat cerebellum.
Topics: Animals; Cats; Cerebellum; Chlorpromazine; Decerebrate State; Dopamine; Evoked Potentials; Female; M | 1987 |
Effects of tizanidine, a centrally acting muscle relaxant, on motor systems.
Topics: Animals; Cerebral Cortex; Chlorpromazine; Clonidine; Decerebrate State; Diazepam; Male; Membranes; M | 1986 |
Pharmacology of M & B 18,706, a drug which selectively reduces decerebrate rigidity.
Topics: Adrenergic alpha-Antagonists; Animals; Apomorphine; Cats; Cerebellar Ataxia; Cerebellum; Chlorpromaz | 1974 |
The effect of diazepam on spinal cord activities: possible sites and mechanisms of action.
Topics: Acetates; Alkaloids; Animals; Anthracenes; Binding Sites; Cats; Chlorpromazine; Decerebrate State; D | 1974 |
The influence of various pharmacological agents on the desynchronization produced by DOPA in the cerveau isolé preparation.
Topics: Animals; Cats; Chlorpromazine; Decerebrate State; Dihydroxyphenylalanine; Disulfiram; Electroencepha | 1970 |
The effects of some drugs on an evoked response sensitive to tetrahydrocannabinols.
Topics: Animals; Atropine; Blood Pressure; Brain; Cannabis; Cerebral Cortex; Chloralose; Chlorpromazine; Dec | 1974 |
Discharges of semitendinosus fusimotor neurones in the decerebrated and spinalized rabbit.
Topics: Animals; Chlorpromazine; Cordotomy; Decerebrate State; Muscle Spindles; Rabbits; Reflex | 1965 |
The effects of ethyl chloride on the muscle spindles of the triceps surae of the rabbit.
Topics: Animals; Chlorpromazine; Decerebrate State; Electrophysiology; Ethyl Chloride; In Vitro Techniques; | 1965 |
A comparison of the actions of some drugs on decerebrate rigidity, muscle spindle activity and alpha-adrenoceptors.
Topics: Animals; Blood Pressure; Cats; Chlorpromazine; Decerebrate State; Desipramine; Dimethylamines; Dose- | 1974 |
Supraspinal interactions of anesthetic, neuroleptic and analeptic drugs on the fusimotor effects of pinna stimulation in the cat.
Topics: Animals; Barbiturates; Bemegride; Blood Pressure; Brain Stem; Cats; Central Nervous System Stimulant | 1970 |
Rigidity in rats due to anemic decerebration and the effect of chlorpromazine.
Topics: Anemia; Animals; Basilar Artery; Carotid Arteries; Cerebrovascular Circulation; Chlorpromazine; Dece | 1974 |
The EEG effects of dopa in the rabbit depending upon the level of brain-stem section.
Topics: Animals; Brain Stem; Cerebral Cortex; Cerebral Decortication; Chlorpromazine; Decerebrate State; Dih | 1974 |
The effects of some drugs on the rigidity of the cat due to ischaemic or intercollicular decerebration.
Topics: Acepromazine; Animals; Carisoprodol; Cats; Cerebrovascular Circulation; Chlorpromazine; Decerebrate | 1972 |
Muscle relaxation by drugs which stimulate sensory nerve endings. I. The effect of veratrum alkaloids, phenyldiguanide and 5-hydroxytryptamine.
Topics: Anesthesia, Inhalation; Animals; Atropine; Biguanides; Blood Circulation; Blood Pressure; Carbamates | 1973 |
Respiratory effects of chlorpromazine in unanesthetized decerebrate cats.
Topics: Animals; Blood Pressure; Carbon Dioxide; Cats; Chemoreceptor Cells; Chlorpromazine; Decerebrate Stat | 1972 |
Muscle relaxants on postischemic spinal rigidity in the rat.
Topics: Animals; Chlorpromazine; Contracture; Decerebrate State; Depression, Chemical; Electromyography; Hin | 1970 |
Caudate nucleus neurones: correlation of the effects of substantia nigra stimulaton with iontophoretic dopamine.
Topics: Acetylcholine; Action Potentials; Animals; Cats; Caudate Nucleus; Chlorpromazine; Decerebrate State | 1970 |
The pharmacology and toxicology of midaflur.
Topics: Analgesics; Animals; Appetite; Avoidance Learning; Benzimidazoles; Body Temperature; Body Weight; Ca | 1971 |
The effect of orphenadrine on neuromuscular transmission.
Topics: Animals; Cats; Chlorpromazine; Decerebrate State; Diaphragm; Muscles; Neuromuscular Junction; Orphen | 1965 |
The role of the central nervous system on the action of epinephrine and adrenolytic drugs.
Topics: Animals; Blood Pressure; Bradycardia; Cats; Central Nervous System; Chlorpromazine; Decerebrate Stat | 1966 |