chlorpromazine has been researched along with De Lange Syndrome in 1 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
De Lange Syndrome: A syndrome characterized by growth retardation, severe MENTAL RETARDATION, short stature, a low-pitched growling cry, brachycephaly, low-set ears, webbed neck, carp mouth, depressed nasal bridge, bushy eyebrows meeting at the midline, hirsutism, and malformations of the hands. The condition may occur sporadically or be associated with an autosomal dominant pattern of inheritance or duplication of the long arm of chromosome 3. (Menkes, Textbook of Child Neurology, 5th ed, p231)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chlorpromazine and fluphenazine decanoate were employed to treat aggressive behavior and emesis in a 22-year-old patient with Cornelia de Lange syndrome." | 3.66 | Pharmacological treatment of aggressive behavior and emesis in the Cornelia de Lange Syndrome. ( Andrasik, F; Hughes, JR; Ollendick, TH; Turner, SM, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andrasik, F | 1 |
| Ollendick, TH | 1 |
| Turner, SM | 1 |
| Hughes, JR | 1 |
1 other study available for chlorpromazine and De Lange Syndrome
| Article | Year |
|---|---|
Pharmacological treatment of aggressive behavior and emesis in the Cornelia de Lange Syndrome.
Topics: Adult; Aggression; Chlorpromazine; De Lange Syndrome; Diazepam; Drug Therapy, Combination; Fluphenaz | 1979 |