chlorpromazine has been researched along with Corneal Diseases in 11 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Corneal Diseases: Diseases of the cornea.
| Excerpt | Relevance | Reference |
|---|---|---|
| " One group was given an intraperitoneal injection daily of CPZ HCl, 5 mg/kg for 4 days followed by 4 more days of a daily dosage of 10 mg/kg." | 1.27 | Chlorpromazine and lithium interaction: a biochemical and histological study. ( Messiha, FS; Sproat, HF; Striegler, RL, 1983) |
| "Chlorpromazine, which has been used extensively for the treatment of psychiatric disorders, is known to accumulate in the posterior corneal stroma, lens, and uveal tract." | 1.26 | Chlorpromazine-induced corneal endothelial phototoxicity. ( Csukas, S; Green, K; Hull, DS, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (45.45) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gupta, A | 1 |
| Agarwal, A | 1 |
| Ram, J | 1 |
| Koh, V | 1 |
| Khor, WB | 1 |
| Lim, L | 1 |
| Phua, YS | 1 |
| Patel, DV | 1 |
| McGhee, CN | 1 |
| Messiha, FS | 1 |
| Sproat, HF | 1 |
| Striegler, RL | 1 |
| Pilger, IS | 1 |
| Hull, DS | 1 |
| Csukas, S | 1 |
| Green, K | 1 |
| Lal, S | 1 |
| Bloom, D | 1 |
| Silver, B | 1 |
| Desjardins, B | 1 |
| Krishnan, B | 1 |
| Thavundayil, J | 1 |
| Thompson, T | 1 |
| Cahane, M | 1 |
| Chen, V | 1 |
| Avni, I | 1 |
| Leung, AT | 1 |
| Cheng, AC | 1 |
| Chan, WM | 1 |
| Lam, DS | 1 |
| Crews, SJ | 1 |
| Lisch, K | 1 |
11 other studies available for chlorpromazine and Corneal Diseases
| Article | Year |
|---|---|
Reversal of toxic manifestations of chlorpromazine.
Topics: Chlorpromazine; Corneal Diseases; Dopamine Antagonists; Eye; Humans; Lens Diseases; Male; Pigmentati | 2014 |
Chlorpromazine-induced corneal toxicity.
Topics: Antipsychotic Agents; Chlorpromazine; Cornea; Corneal Diseases; Diagnosis, Differential; Humans; Mal | 2012 |
In vivo confocal microstructural analysis of corneal endothelial changes in a patient on long-term chlorpromazine therapy.
Topics: Chlorpromazine; Corneal Diseases; Dopamine Antagonists; Endothelium, Corneal; Female; Humans; Micros | 2005 |
Chlorpromazine and lithium interaction: a biochemical and histological study.
Topics: Alcohol Oxidoreductases; Animals; Chlorides; Chlorpromazine; Corneal Diseases; Drug Interactions; Et | 1983 |
Pigmentation of the cornea: a review and classification.
Topics: Adult; Child; Chloroquine; Chlorpromazine; Corneal Diseases; Drug-Related Side Effects and Adverse R | 1983 |
Chlorpromazine-induced corneal endothelial phototoxicity.
Topics: Animals; Chlorpromazine; Cornea; Corneal Diseases; Edema; Endothelium; In Vitro Techniques; Rabbits; | 1982 |
Replacement of chlorpromazine with other neuroleptics: effect on abnormal skin pigmentation and ocular changes.
Topics: Adult; Antipsychotic Agents; Chlorpromazine; Cornea; Corneal Diseases; Female; Follow-Up Studies; Ha | 1993 |
Persistent chlorpromazine deposits in donor corneal tissue after corneal transplantation.
Topics: Adult; Antipsychotic Agents; Chlorpromazine; Cornea; Corneal Diseases; Corneal Transplantation; Endo | 1997 |
Chlorpromazine-induced refractile corneal deposits and cataract.
Topics: Antipsychotic Agents; Cataract; Chlorpromazine; Corneal Diseases; Female; Humans; Middle Aged | 1999 |
Ocular adverse reactions to drugs.
Topics: Adrenal Cortex Hormones; Adult; Aged; Amblyopia; Cataract; Chloroquine; Chlorpromazine; Conjunctivit | 1977 |
[Ophthalmic-pharmacological complications (author's transl)].
Topics: Atropine; Chlorpromazine; Corneal Diseases; Eye Diseases; Humans; Male; Middle Aged; Mydriatics; Phe | 1976 |