Compounds > chlorpromazine
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chlorpromazine and Coma

chlorpromazine has been researched along with Coma in 25 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Coma: A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.

Research Excerpts

ExcerptRelevanceReference
"A case of myxoedema coma is reported where the administration of chlorpromazine resulted in a prolonged dystonic reaction."7.66Prolonged dystonic reaction to chlorpromazine in myxoedema coma. ( Waters, AK; Wood, GM, 1980)
"A case of myxoedema coma is reported where the administration of chlorpromazine resulted in a prolonged dystonic reaction."3.66Prolonged dystonic reaction to chlorpromazine in myxoedema coma. ( Waters, AK; Wood, GM, 1980)
"On arrival, the Japan coma scale, pulse, respiratory rate, body temperature, and Sp(O2) were 300, 114 beats x min(-1), 26 breaths x min(-1), 39."1.38[Comatose patient with neuroleptic malignant syndrome brought by ambulance]. ( Kuroda, Y; Takinami, Y, 2012)
"A 41-year-old man in deep coma after drug overdosage showed electroencephalographic activity of alpha frequency."1.26Recovery from drug-induced alpha coma. ( Furukawa, T; Inaki, K; Kuroiwa, Y, 1981)
"Excitation, coma, convulsions, tachycardia, mydriasis, nystagmus, and rubeosis of the face were the most important signs."1.26[Fenfluramin (ponderax) intoxications in children (author's transl)]. ( Krienke, EG; Mühlendahl, KE, 1978)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199022 (88.00)18.7374
1990's1 (4.00)18.2507
2000's0 (0.00)29.6817
2010's2 (8.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Matsumoto, H1
Umakoshi, K1
Kikuchi, S1
Takeba, J1
Aibiki, M1
Takinami, Y1
Kuroda, Y1
TASSIS, JA1
HAMILTON, UH1
LAPOLLA, A1
NASH, LR1
Goulon, M1
Nouailhat, F1
Lévy-Alcover, MA1
Dordain, G1
Buckle, RM1
Guillebaud, J1
Ott, VV1
Pollack, MM1
Riddick, L1
Reisch, RF1
Epstein, BS1
Kuroiwa, Y1
Furukawa, T1
Inaki, K1
Wood, GM1
Waters, AK1
Mühlendahl, KE1
Krienke, EG1
Quenstedt, M1
Ramsay, R1
Bernadt, M1
Singh, BJ1
Chandavasu, O1
Chatkupt, S1
Neveu, P1
Marrel, P1
Marchandon, AM1
Pautet, P1
Plotnikoff, N1
Will, F1
Ditzler, W1
Bevegård, S1
Thorstrand, C1
Markiewicz, K1
Trznadel, K1
Cholewa, M1
Bazhin, EF1
Rafalovich, EG1
Prien, RF1
Caffey, EM1
Klett, CJ1
Penn, AS1
Rowland, LP1
Fraser, DW1
Pinkus, NB1
Fréjaville, JP1
Guyochin, A1
Gaultier, M1
Henry, P1
Barat, M1
Bourgeois, M1
Tignol, P1
Milner, G1

Reviews

1 review available for chlorpromazine and Coma

ArticleYear
Lithium carbonate. A survey of the history and current status of Lithium in treating mood disorders.
    Diseases of the nervous system, 1971, Volume: 32, Issue:8

    Topics: Bipolar Disorder; Carbonates; Chlorpromazine; Clinical Trials as Topic; Coma; Depression; Epilepsy;

1971

Trials

1 trial available for chlorpromazine and Coma

ArticleYear
Lithium carbonate. A survey of the history and current status of Lithium in treating mood disorders.
    Diseases of the nervous system, 1971, Volume: 32, Issue:8

    Topics: Bipolar Disorder; Carbonates; Chlorpromazine; Clinical Trials as Topic; Coma; Depression; Epilepsy;

1971

Other Studies

24 other studies available for chlorpromazine and Coma

ArticleYear
[BIS values were useful on the evaluation of consciousness recovery in acute Vegetamin-A poisoning: report of a case].
    Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology, 2014, Volume: 27, Issue:4

    Topics: Acute Disease; Adult; Charcoal; Chlorpromazine; Coma; Consciousness Monitors; Drug Combinations; Ene

2014
[Comatose patient with neuroleptic malignant syndrome brought by ambulance].
    Masui. The Japanese journal of anesthesiology, 2012, Volume: 61, Issue:1

    Topics: Adult; Ambulances; Basal Ganglia Diseases; Chlorpromazine; Coma; Dantrolene; Drug Overdose; Female;

2012
Full coma insulin therapy, chlorpromazine and electroconvulsive treatment: a control study of 600 schizophrenic patients.
    The Medical journal of Malaya, 1959, Volume: 14

    Topics: Chlorpromazine; Coma; Convulsive Therapy; Electroconvulsive Therapy; Humans; Insulins; Schizophrenia

1959
COMA DUE TO FAT-EMBOLISM TREATED WITH HYPOTHERMIA AND DEHYDRATION.
    Lancet (London, England), 1964, Nov-07, Volume: 2, Issue:7367

    Topics: Chlorpromazine; Coma; Dehydration; Diuresis; Embolism; Embolism, Fat; Fibula; Fracture Fixation; Hum

1964
TWO SUICIDE ATTEMPTS WITH CHLORPROMAZINE.
    The American journal of psychiatry, 1965, Volume: 121

    Topics: Amphetamine; Chlorpromazine; Coma; Depression; Dextroamphetamine; Drug Therapy; Gastric Lavage; Hypo

1965
[Toxic coma with autonomic sideration, with a favorable outcome].
    Revue neurologique, 1967, Volume: 116, Issue:4

    Topics: Adult; Amobarbital; Body Temperature; Brain; Cardiovascular System; Chlorpromazine; Coma; Diazepam;

1967
Hypoglycaemic coma occurring during treatment with chlorpromazine and orphenadrine.
    British medical journal, 1967, Dec-09, Volume: 4, Issue:5579

    Topics: Blood Glucose; Chlorpromazine; Coma; Female; Humans; Hypoglycemia; Mental Disorders; Middle Aged; Or

1967
Delayed awakening from anesthesia and child abuse.
    Anesthesiology, 1983, Volume: 58, Issue:2

    Topics: Anesthesiology; Arousal; Child; Child Abuse; Chlorpromazine; Coma; Female; Homicide; Humans; Jurispr

1983
Recovery from drug-induced alpha coma.
    Neurology, 1981, Volume: 31, Issue:10

    Topics: Adult; Alpha Rhythm; Chlorpromazine; Coma; Diazepam; Humans; Male; Phenobarbital; Suicide, Attempted

1981
Prolonged dystonic reaction to chlorpromazine in myxoedema coma.
    Postgraduate medical journal, 1980, Volume: 56, Issue:653

    Topics: Aged; Chlorpromazine; Coma; Dystonia; Female; Humans; Myxedema

1980
[Fenfluramin (ponderax) intoxications in children (author's transl)].
    Monatsschrift fur Kinderheilkunde, 1978, Volume: 126, Issue:10

    Topics: Adolescent; Adrenergic beta-Antagonists; Anticonvulsants; Child, Preschool; Chlorpromazine; Coma; El

1978
Rapid tranquillisation.
    The British journal of psychiatry : the journal of mental science, 1992, Volume: 161

    Topics: Adult; Arousal; Chlorpromazine; Coma; Diazepam; Dose-Response Relationship, Drug; Drug Therapy, Comb

1992
Largactil in pyogenic meningitis (relapse case)
    The Journal of the Association of Physicians of India, 1989, Volume: 37, Issue:7

    Topics: Chlorpromazine; Coma; Humans; Male; Meningitis; Recurrence

1989
Central nervous system depression from chlorpromazine poisoning: successful treatment with naloxone.
    The Journal of pediatrics, 1985, Volume: 106, Issue:3

    Topics: Central Nervous System; Child, Preschool; Chlorpromazine; Coma; Depression, Chemical; Gastric Lavage

1985
[Malignant catatonia. Treatment using hibernation].
    Annales medico-psychologiques, 1973, Volume: 2, Issue:2

    Topics: Adolescent; Body Temperature; Catatonia; Chlorpromazine; Coma; Electroencephalography; Ergoloid Mesy

1973
Stimulant activity of pemoline and magnesium hydroxide.
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 181, Issue:2

    Topics: Animals; Antacids; Ataxia; Caffeine; Cats; Central Nervous System Stimulants; Chlordiazepoxide; Chlo

1969
Central hemodynamics in severe poisoning by hypnotic drugs. Coma depth and body temperature.
    Acta medica Scandinavica, 1972, Volume: 191, Issue:4

    Topics: Adult; Aged; Amitriptyline; Blood Pressure; Body Temperature; Cardiac Output; Central Venous Pressur

1972
[Acute chlorpromazine poisoning].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1973, Apr-01, Volume: 26, Issue:7

    Topics: Acute Disease; Adolescent; Adult; Chlorpromazine; Coma; Female; Humans; Jaundice; Male; Middle Aged;

1973
[Treatment of hallucinatory disorders in schizophrenia with atropine comas].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1973, Volume: 73, Issue:8

    Topics: Amitriptyline; Atropine; Chlorpromazine; Coma; Drug Therapy, Combination; Epinephrine; Hallucination

1973
Drugs, coma, and myoglobinuria.
    Archives of neurology, 1972, Volume: 26, Issue:4

    Topics: Acute Kidney Injury; Adult; Aspartate Aminotransferases; Barbiturates; Chlorpromazine; Coma; Drug-Re

1972
Skin eruptions in drug-induced coma.
    The Medical journal of Australia, 1971, Oct-30, Volume: 2, Issue:18

    Topics: Adult; Barbiturates; Chlorpromazine; Coma; Humans; Middle Aged; Shock, Septic; Skin Diseases; Skin M

1971
[152 cases of acute poisoning by phenothiazine amines].
    European journal of toxicology, 1970, Volume: 3, Issue:3

    Topics: Absorption; Adolescent; Adult; Aged; Agranulocytosis; Anesthesia, General; Anesthesia, Obstetrical;

1970
[Fatal malignant syndromes following direct injection of fluphenazine onanthate].
    La Presse medicale, 1971, Jun-12, Volume: 79, Issue:29

    Topics: Adult; Chlorpromazine; Coma; Fever; Fluphenazine; Humans; Male; Mental Disorders; Phenothiazines; Tr

1971
The effect of antidepressants and "tranquilizers" on the response of mice to ethanol.
    British journal of pharmacology, 1968, Volume: 34, Issue:2

    Topics: Accidents, Traffic; Amitriptyline; Animals; Antidepressive Agents; Chlorpromazine; Coma; Desipramine

1968