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chlorpromazine and Chronic Kidney Failure

chlorpromazine has been researched along with Chronic Kidney Failure in 10 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Research Excerpts

ExcerptRelevanceReference
"To assess the importance of disease-induced increases in plasma concentrations of alpha1 acid glycoprotein (an acute-phase plasma protein that binds cationic drugs), we determined binding of propranolol in plasma from 53 patients and 25 healthy volunteers."7.66Increased plasma protein binding of propranolol and chlorpromazine mediated by disease-induced elevations of plasma alpha1 acid glycoprotein. ( Borgá, O; Johansson, C; Odar-Cederlöf, I; Piafsky, KM; Sjöqvist, F, 1978)
"To assess the importance of disease-induced increases in plasma concentrations of alpha1 acid glycoprotein (an acute-phase plasma protein that binds cationic drugs), we determined binding of propranolol in plasma from 53 patients and 25 healthy volunteers."3.66Increased plasma protein binding of propranolol and chlorpromazine mediated by disease-induced elevations of plasma alpha1 acid glycoprotein. ( Borgá, O; Johansson, C; Odar-Cederlöf, I; Piafsky, KM; Sjöqvist, F, 1978)
"A case of sudden death following chlorpromazine administration in a schizophrenic patient is presented."1.27Chlorpromazine accumulation and sudden death in a patient with renal insufficiency. ( Crismon, ML; Dorson, PG, 1988)
"Four patients with chronic renal failure requiring hemodialysis were given doses of chlorpromazine ranging from 100--1000 mg over time intervals varying from 2--7 days."1.26Toxic psychosis induced by phenothiazine administration in patients with chronic renal failure. ( McAllister, CJ; Scowden, EB; Stone, WJ, 1978)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19909 (90.00)18.7374
1990's1 (10.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fabre, J2
de Freudenreich, J2
Duckert, A2
Pitton, JS2
Rudhardt, M2
Virieux, C1
Grzeszczak, W1
Kokot, F1
Dulawa, J1
Piafsky, KM1
Borgá, O1
Odar-Cederlöf, I1
Johansson, C1
Sjöqvist, F1
Ramirez, G1
O'Neill, WM1
Bloomer, HA1
Jubiz, W1
McAllister, CJ1
Scowden, EB1
Stone, WJ1
Kalra, OP1
Aggarwal, HK1
Mahajan, SK1
Seth, RK1
Dorson, PG1
Crismon, ML1
Stage, P1
Milman, N1
Brix, E1
Murphy, KJ1

Trials

1 trial available for chlorpromazine and Chronic Kidney Failure

ArticleYear
Effect of vasodilator and surface active drugs on the efficacy of peritoneal dialysis.
    The Journal of the Association of Physicians of India, 1992, Volume: 40, Issue:4

    Topics: Acute Kidney Injury; Adult; Aged; Chlorpromazine; Dialysis Solutions; Female; Humans; Kidney Failure

1992

Other Studies

9 other studies available for chlorpromazine and Chronic Kidney Failure

ArticleYear
Influence of renal insufficiency on the excretion of chloroquine, phenobarbital, phenothiazines and methacycline.
    Helvetica medica acta, 1967, Volume: 33, Issue:4

    Topics: Adult; Aged; Chloroquine; Chlorpromazine; Glomerular Filtration Rate; Humans; Kidney Failure, Chroni

1967
Influence of naloxone on prolactin secretion in patients with acute and chronic renal failure.
    Clinical nephrology, 1984, Volume: 21, Issue:1

    Topics: Acute Kidney Injury; Adult; Chlorpromazine; Female; Humans; Kidney Failure, Chronic; Male; Naloxone;

1984
Increased plasma protein binding of propranolol and chlorpromazine mediated by disease-induced elevations of plasma alpha1 acid glycoprotein.
    The New England journal of medicine, 1978, Dec-28, Volume: 299, Issue:26

    Topics: Adult; Aged; alpha-Macroglobulins; Arthritis; Chlorpromazine; Crohn Disease; Disease; Female; Humans

1978
Abnormalities in the regulation of prolactin in patients with chronic renal failure.
    The Journal of clinical endocrinology and metabolism, 1977, Volume: 45, Issue:4

    Topics: Adult; Chlorpromazine; Humans; Kidney Failure, Chronic; Levodopa; Male; Middle Aged; Prolactin; Thyr

1977
Toxic psychosis induced by phenothiazine administration in patients with chronic renal failure.
    Clinical nephrology, 1978, Volume: 10, Issue:5

    Topics: Aged; Chlorpromazine; Humans; Kidney Failure, Chronic; Male; Middle Aged; Promethazine; Psychoses, S

1978
Chlorpromazine accumulation and sudden death in a patient with renal insufficiency.
    Drug intelligence & clinical pharmacy, 1988, Volume: 22, Issue:10

    Topics: Chlorpromazine; Death, Sudden; Humans; Kidney Failure, Chronic; Male; Middle Aged; Schizophrenia

1988
High-dose urography in advanced renal failure. I. Evaluation of diagnostic value.
    Acta radiologica: diagnosis, 1973, Volume: 14, Issue:6

    Topics: Acute Kidney Injury; Adult; Aged; Aniline Compounds; Benzyl Compounds; Blood Urea Nitrogen; Blood Vi

1973
[Influence of renal insufficiency on the excretion of diverse drugs (chloroquine, sedatives, methacycline)].
    Helvetica medica acta. Supplementum, 1966, May-15, Volume: 46

    Topics: Barbiturates; Chloroquine; Chlorpromazine; Creatinine; Humans; Hypnotics and Sedatives; Kidney Failu

1966
Uraemic accentuation of chlorpromazine pigmentation.
    The Medical journal of Australia, 1966, Dec-24, Volume: 2, Issue:26

    Topics: Adult; Chlorpromazine; Conjunctiva; Humans; Kidney Failure, Chronic; Male; Melanosis; Nausea; Uremia

1966