chlorpromazine has been researched along with Cerebral Ischemia in 9 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Spinal cord ischemia was obtained by clamping the abdominal aorta caudally to the renal arteries for 30 min, after which it was released and the animals were observed for a period of 48 hrs." | 1.31 | The protective action of chlorpromazine on the spinal cord of rabbits submitted to ischemia and reperfusion is dose-dependent. ( Alves, P; Barbieri-Neto, J; Mazzetto, SA; Sader, AA; Sader, SL; Vanni, JC, 2002) |
| "Chlorpromazine was effective despite reduction of blood pressure, and trifluoperazine did not alter blood pressure." | 1.28 | Phenothiazines reduce ischemic damage to the central nervous system. ( Kochhar, A; Saitoh, T; Zivin, JA, 1989) |
| "The neuroleptic malignant syndrome is a rare but dangerous complication of treatment with neuroleptics." | 1.28 | Neuroleptic malignant syndrome: a case report with post-mortem brain and muscle pathology. ( Dawson, A; Jones, EM, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Monjas, L | 1 |
| Arce, MP | 1 |
| León, R | 1 |
| Egea, J | 1 |
| Pérez, C | 1 |
| Villarroya, M | 1 |
| López, MG | 1 |
| Gil, C | 1 |
| Conde, S | 1 |
| Rodríguez-Franco, MI | 1 |
| Li, F | 1 |
| Geng, X | 2 |
| Yip, J | 1 |
| Ding, Y | 2 |
| Liu, S | 1 |
| Forreider, B | 1 |
| Xiao, Y | 1 |
| Kong, Q | 1 |
| Ji, X | 1 |
| Sader, AA | 1 |
| Barbieri-Neto, J | 1 |
| Sader, SL | 1 |
| Mazzetto, SA | 1 |
| Alves, P | 1 |
| Vanni, JC | 1 |
| Ishihara, N | 1 |
| Gotoh, F | 1 |
| Seif el Nasr, M | 1 |
| Nuglisch, J | 1 |
| Krieglstein, J | 1 |
| Zivin, JA | 1 |
| Kochhar, A | 1 |
| Saitoh, T | 1 |
| Jones, EM | 1 |
| Dawson, A | 1 |
1 review available for chlorpromazine and Cerebral Ischemia
| Article | Year |
|---|---|
[Cerebral metabolic activator (author's transl)].
Topics: Adenosine Triphosphate; Animals; Barbiturates; Biogenic Amines; Biotransformation; Brain; Brain Isch | 1979 |
1 trial available for chlorpromazine and Cerebral Ischemia
| Article | Year |
|---|---|
Cerebral symptoms and blood pressure during parenteral administration of chlorpromazine, dihydralazine and diazoxide. Danish multicenter study on acute severe hypertension.
Topics: Blood Pressure; Brain Diseases; Brain Ischemia; Chlorpromazine; Clinical Trials as Topic; Diazoxide; | 1983 |
7 other studies available for chlorpromazine and Cerebral Ischemia
| Article | Year |
|---|---|
Enzymatic and solid-phase synthesis of new donepezil-based L- and d-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia.
Topics: Alzheimer Disease; Animals; Brain Ischemia; Calcium Channel Blockers; Cholinesterase Inhibitors; Don | 2017 |
Therapeutic Target and Cell-signal Communication of Chlorpromazine and Promethazine in Attenuating Blood-Brain Barrier Disruption after Ischemic Stroke.
Topics: Animals; Blood-Brain Barrier; Brain Ischemia; Chlorpromazine; Male; Promethazine; Rats; Rats, Spragu | 2019 |
Enhanced beneficial effects of mild hypothermia by phenothiazine drugs in stroke therapy.
Topics: Animals; Body Temperature; Brain; Brain Ischemia; Chlorpromazine; Hypothermia, Induced; Male; Motor | 2015 |
The protective action of chlorpromazine on the spinal cord of rabbits submitted to ischemia and reperfusion is dose-dependent.
Topics: Animals; Biopsy, Needle; Brain Ischemia; Chlorpromazine; Disease Models, Animal; Dose-Response Relat | 2002 |
Prevention of ischemia-induced cerebral hypothermia by controlling the environmental temperature.
Topics: Animals; Body Temperature; Body Temperature Regulation; Brain; Brain Ischemia; Chlorpromazine; Disea | 1992 |
Phenothiazines reduce ischemic damage to the central nervous system.
Topics: Animals; Brain Ischemia; Chlorpromazine; Ischemia; Phenothiazines; Rabbits; Spinal Cord; Trifluopera | 1989 |
Neuroleptic malignant syndrome: a case report with post-mortem brain and muscle pathology.
Topics: Aged; Brain; Brain Ischemia; Chlorpromazine; Depressive Disorder; Drug Therapy, Combination; Female; | 1989 |