chlorpromazine has been researched along with Catatonic Rigidity in 21 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "These results suggest that RF decerebrate rigidity can be used instead of intercollicular transection rigidity in the pharmacological and physiological studies." | 1.27 | Rigidity in rats due to radio frequency decerebration and effects of chlorpromazine and mephenesin. ( Fukuda, H; Ito, H; Nakamura, T; Oka, J; Ono, H, 1987) |
| "Presumably, the syndrome is secondary to biochemical dysfunction of the basal ganglia and possible of the hypothalmus." | 1.26 | Neuroleptic malignant syndrome. ( McCormick, WF; Morris, HH; Reinarz, JA, 1980) |
| "Chlorpromazine that depresses decerebrate rigidity in a dose-related fashion requires 1." | 1.26 | Suppression of decerebrate rigidity by phenytoin and chlorpromazine. ( Anderson, RJ; Raines, A, 1976) |
| "It is likely that these drugs reduce decerebrate rigidity by inhibiting fusimotor activity." | 1.25 | A comparison of the actions of some drugs on decerebrate rigidity, muscle spindle activity and alpha-adrenoceptors. ( Maxwell, DR; Sumpter, EA, 1974) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (80.95) | 18.7374 |
| 1990's | 3 (14.29) | 18.2507 |
| 2000's | 1 (4.76) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| MARTIN, FI | 1 |
| DI PERRI, R | 1 |
| GIAQUINTO, S | 1 |
| Singh, D | 1 |
| Forlano, R | 1 |
| Athey, R | 1 |
| Morris, HH | 1 |
| McCormick, WF | 1 |
| Reinarz, JA | 1 |
| Baker, RW | 1 |
| Chengappa, KN | 1 |
| Hemsley, KM | 1 |
| Crocker, AD | 1 |
| Leber, K | 1 |
| Malek, A | 1 |
| D'Agostino, A | 1 |
| Adelman, HM | 1 |
| Anderson, RJ | 1 |
| Raines, A | 1 |
| Jurna, I | 1 |
| Hall, GM | 1 |
| Lucke, JN | 1 |
| Lister, D | 1 |
| Beasley, BA | 1 |
| Ford, DH | 1 |
| Share, NN | 1 |
| McFarlane, CS | 1 |
| Ono, H | 1 |
| Nakamura, T | 1 |
| Ito, H | 1 |
| Oka, J | 1 |
| Fukuda, H | 2 |
| Maxwell, DR | 3 |
| Read, MA | 2 |
| Sumpter, EA | 2 |
| Steg, G | 1 |
| Petersen, EA | 1 |
| Haase, J | 1 |
| Ito, T | 1 |
| Hashimoto, S | 1 |
| Kudo, Y | 1 |
| McClelland, HA | 1 |
| Blessed, G | 1 |
| Bhate, S | 1 |
| Ali, N | 1 |
| Clarke, PA | 1 |
| Schulterbrandt, JG | 1 |
| Raskin, A | 1 |
| Reatig, N | 1 |
4 reviews available for chlorpromazine and Catatonic Rigidity
| Article | Year |
|---|---|
Striatal monoamines and reserpine and chlorpromazine rigidity.
Topics: Animals; Biogenic Amines; Cats; Chlorpromazine; Corpus Striatum; Dopamine; Humans; Mice; Motor Neuro | 1976 |
Treatment of porcine malignant hyperthermia. A review based on experimental studies.
Topics: Animals; Blood Glucose; Body Temperature; Carbon Dioxide; Catecholamines; Chlorpromazine; Dantrolene | 1975 |
Aging and the extrapyramidal system.
Topics: Aged; Aging; Basal Ganglia Diseases; Chlorpromazine; Chorea; Dopamine; Frontal Lobe; Gait; Haloperid | 1976 |
Pathological aspects on Parkinson's syndrome.
Topics: Animals; Basal Ganglia; Basal Ganglia Diseases; Central Nervous System; Chlorpromazine; Corpus Stria | 1972 |
2 trials available for chlorpromazine and Catatonic Rigidity
| Article | Year |
|---|---|
The abrupt withdrawal of antiparkinsonian drugs in schizophrenic patients.
Topics: Adult; Aged; Antiparkinson Agents; Basal Ganglia Diseases; Behavior; Chlorpromazine; Clinical Trials | 1974 |
True and apparent side effects in a controlled trial of chlorpromazine and imipramine in depression.
Topics: Adult; Agranulocytosis; Chlorpromazine; Clinical Trials as Topic; Depression; Dermatitis; Edema; Eva | 1974 |
15 other studies available for chlorpromazine and Catatonic Rigidity
| Article | Year |
|---|---|
The use of chlorpromazine to control spasm and rigidity in tetanus: report of a case.
Topics: Chlorpromazine; Muscle Rigidity; Spasm; Tetanus | 1957 |
[Chlorpromazine, Jendrassi's maneuver and parkinsonian rigor].
Topics: Chlorpromazine; Electroencephalography; Electromyography; Muscle Rigidity; Nervous System Physiologi | 1962 |
Neuroleptic malignant syndrome and catatonia in a patient with dementia.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Catatonia; Chlorpromazine; Choline | 2008 |
Neuroleptic malignant syndrome.
Topics: Adult; Basal Ganglia; Chlorpromazine; Fever; Humans; Hypothalamus; Male; Muscle Rigidity; Syndrome | 1980 |
Further study of neuroleptic malignant syndrome.
Topics: Adult; Chlorpromazine; Fever; Humans; Male; Muscle Rigidity; Neuroleptic Malignant Syndrome; Psychia | 1995 |
Raclopride and chlorpromazine, but not clozapine, increase muscle rigidity in the rat: relationship with D2 dopamine receptor occupancy.
Topics: Animals; Antipsychotic Agents; Autoradiography; Brain Chemistry; Chlorpromazine; Clozapine; Dose-Res | 1999 |
A veteran with acute mental changes years after combat.
Topics: Antipsychotic Agents; Chlorpromazine; Diagnosis, Differential; Humans; Lithium; Male; Middle Aged; M | 1999 |
Suppression of decerebrate rigidity by phenytoin and chlorpromazine.
Topics: Animals; Cats; Chlorpromazine; Decerebrate State; Disease Models, Animal; Dose-Response Relationship | 1976 |
Cyclobenzaprine: novel centrally acting skeletal muscle relaxant.
Topics: Amitriptyline; Animals; Anticonvulsants; Ataxia; Cats; Chlorpromazine; Decerebrate State; Diazepam; | 1975 |
Rigidity in rats due to radio frequency decerebration and effects of chlorpromazine and mephenesin.
Topics: Animals; Chlorpromazine; Decerebrate State; Male; Mephenesin; Muscle Rigidity; Radio Waves; Rats; Ra | 1987 |
Pharmacology of M & B 18,706, a drug which selectively reduces decerebrate rigidity.
Topics: Adrenergic alpha-Antagonists; Animals; Apomorphine; Cats; Cerebellar Ataxia; Cerebellum; Chlorpromaz | 1974 |
A comparison of the actions of some drugs on decerebrate rigidity, muscle spindle activity and alpha-adrenoceptors.
Topics: Animals; Blood Pressure; Cats; Chlorpromazine; Decerebrate State; Desipramine; Dimethylamines; Dose- | 1974 |
Unstable fractures in children with acute, severe brain injury.
Topics: Accidents, Traffic; Arm Injuries; Brain Injuries; Chlorpromazine; Female; Femoral Fractures; Fractur | 1974 |
Rigidity in rats due to anemic decerebration and the effect of chlorpromazine.
Topics: Anemia; Animals; Basilar Artery; Carotid Arteries; Cerebrovascular Circulation; Chlorpromazine; Dece | 1974 |
The effects of some drugs on the rigidity of the cat due to ischaemic or intercollicular decerebration.
Topics: Acepromazine; Animals; Carisoprodol; Cats; Cerebrovascular Circulation; Chlorpromazine; Decerebrate | 1972 |