chlorpromazine has been researched along with Cataract in 48 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Cataract: Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chlorpromazine is a low potency "typical" antipsychotic agent used to treat schizophrenia." | 3.85 | Kerato-lenticular ocular deposits and visual impairment with prolonged chlorpromazine use: A case series. ( Gowda, GS; Hegde, A; Jaisoorya, TS; Narayanaswamy, JC; Shanbhag, V, 2017) |
| " We analyzed the prevalence of ocular side effects of chlorpromazine and found that the most prevalent side effect was anterior lens capsule dusting followed by corneal stromal pigment dusting." | 1.27 | The prevalence of the ocular side effects of chlorpromazine in the Tuscaloosa Veterans Administration patient population. ( Alexander, LJ; Bowerman, L; Thompson, LR, 1985) |
| " The risk of using chlorpromazine in moderate dosage is slight." | 1.26 | Deposits in the lens and cornea of the eye during long-term chlorpromazine medication. ( Faurbye, A; Kirk, L; Rasmussen, K, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 45 (93.75) | 18.7374 |
| 1990's | 1 (2.08) | 18.2507 |
| 2000's | 1 (2.08) | 29.6817 |
| 2010's | 1 (2.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gowda, GS | 1 |
| Hegde, A | 1 |
| Shanbhag, V | 1 |
| Narayanaswamy, JC | 1 |
| Jaisoorya, TS | 1 |
| HARLEY, RD | 3 |
| MISHLER, JE | 3 |
| TOWNES, CD | 1 |
| MANN, SH | 1 |
| LOW, H | 1 |
| AGARWAL, LP | 1 |
| GUPTA, RB | 1 |
| MALIK, SR | 1 |
| CESA, R | 1 |
| MARTINELLI, G | 1 |
| GREINER, AC | 1 |
| BERRY, K | 1 |
| BHATNAGAR, BS | 1 |
| MASSEY, LW | 1 |
| BARSA, JA | 1 |
| NEWTON, JC | 1 |
| SAUNDERS, JC | 1 |
| MARGOLIS, LH | 1 |
| GOBLE, JL | 1 |
| Weinstock, M | 2 |
| Scott, JD | 1 |
| Schönthaler, M | 1 |
| Westlin, WF | 1 |
| Gualtieri, CT | 1 |
| Lefler, WH | 1 |
| Guimond, M | 1 |
| Staye, JI | 1 |
| Deluise, VP | 1 |
| Flynn, JT | 1 |
| Leung, AT | 1 |
| Cheng, AC | 1 |
| Chan, WM | 1 |
| Lam, DS | 1 |
| Ruigómez, A | 1 |
| García Rodríguez, LA | 1 |
| Dev, VJ | 1 |
| Arellano, F | 1 |
| Raniwala, J | 1 |
| Crews, SJ | 1 |
| Koch, HR | 2 |
| Hockwin, O | 2 |
| Setogawa, T | 1 |
| Tamai, A | 1 |
| Matsuura, H | 1 |
| Ogura, C | 1 |
| Rasmussen, K | 1 |
| Kirk, L | 1 |
| Faurbye, A | 1 |
| Alexander, LJ | 1 |
| Bowerman, L | 1 |
| Thompson, LR | 1 |
| Gehring, PJ | 1 |
| Barg, TsM | 1 |
| Verrey, F | 1 |
| Cuendet, JF | 1 |
| Nouri, A | 1 |
| Marzulli, FN | 1 |
| Appleton, WS | 1 |
| Shader, RI | 1 |
| DiMascio, A | 1 |
| Abakumov, VM | 1 |
| Vikhliaev, IuI | 1 |
| Bernstein, HN | 1 |
| Buffaloe, WJ | 1 |
| Johnson, AW | 1 |
| Sandifer, MG | 1 |
| Baron, JB | 1 |
| Rivoalan, Y | 1 |
| Morel, P | 1 |
| Edler, K | 2 |
| Gottfries, CG | 1 |
| Haslund, J | 1 |
| Ravn, J | 1 |
| Gol'dovskaia, IL | 1 |
| Boet, DJ | 1 |
| Fraunfelder, FT | 2 |
| Burns, RP | 2 |
| Siddall, JR | 3 |
| Marshall, AS | 1 |
| Howard, RO | 1 |
| McDonald, CJ | 1 |
| Dunn, B | 1 |
| Creasey, WA | 1 |
| Smith, AA | 1 |
| Gavitt, JA | 1 |
| Karmin, M | 1 |
| Dencker, SJ | 1 |
| Enoksson, P | 1 |
6 reviews available for chlorpromazine and Cataract
| Article | Year |
|---|---|
The cataractogenic activity of chemical agents.
Topics: Adrenal Cortex Hormones; Alkylating Agents; Aniline Compounds; Carbohydrates; Cataract; Chemical Phe | 1971 |
[Eye complications during use of various medicinal substances with general effects (review of the literature)].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Allopurinol; Anti-Bacterial Agents; Antimalari | 1969 |
Ocular side effects of drugs.
Topics: Animals; Cataract; Chlorpromazine; Dogs; Drug-Related Side Effects and Adverse Reactions; Electroret | 1968 |
Ocular (pigmentary) effects of psychotropic drugs.
Topics: Cataract; Chlorpromazine; Corneal Opacity; Humans; Phenothiazines; Pigmentation Disorders; Tranquili | 1970 |
[The metabolism of psychotropic drugs (phenothiazine and iminodibenzyl derivatives)].
Topics: Animals; Antidepressive Agents; Cataract; Chemical Phenomena; Chemistry; Chlorpromazine; Dogs; Human | 1970 |
Some iatrogenic ocular diseases from systemically administered drugs.
Topics: Animals; Cataract; Cats; Chemical Phenomena; Chemistry; Chloramphenicol; Chloroquine; Chlorpromazine | 1970 |
42 other studies available for chlorpromazine and Cataract
| Article | Year |
|---|---|
Kerato-lenticular ocular deposits and visual impairment with prolonged chlorpromazine use: A case series.
Topics: Adult; Antipsychotic Agents; Cataract; Chlorpromazine; Cornea; Female; Humans; Lens Capsule, Crystal | 2017 |
The use of chlorpromazine in cataract surgery; a preliminary report.
Topics: Cataract; Cataract Extraction; Chlorpromazine; Lens, Crystalline | 1957 |
Intravenous sedation in cataract surgery.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Cataract; Cataract Extraction; Chlorpromazine; Huma | 1958 |
Ataractic and antiemetic drugs in cataract surgery.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Antiemetics; Cataract; Cataract Extraction; Chlorpr | 1959 |
The effects of promazines on mitochondrial adenosine triphosphatase reactions.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Cataract; Chlorpromazine; Humans; Phenothiazines; | 1959 |
Ataractic and anti-emetic drugs in cataract surgery.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Antiemetics; Cataract; Cataract Extraction; Chlorpr | 1958 |
Drug administration in cataract surgery.
Topics: Acetazolamide; Cataract; Cataract Extraction; Chlorpromazine; Curare; Humans; Lens, Crystalline | 1959 |
[THE USE OF CURARE IN CATARACT SURGERY. CLINICO-STATISTICAL CONTRIBUTION].
Topics: Anesthesia; Anesthesiology; Cataract; Cataract Extraction; Chlorpromazine; Curare; Hibernation; Huma | 1963 |
SKIN PIGMENTATION AND CORNEAL AND LENS OPACITIES WITH PROLONGED CHLORPROMAZINE THERAPY.
Topics: Cataract; Chlorpromazine; Cornea; Corneal Opacity; Female; Humans; Lens, Crystalline; Melanins; Opht | 1964 |
INTRA-OCULAR PRESSURE IN CATARACT SURGERY.
Topics: Cataract; Cataract Extraction; Chlorpromazine; Humans; Intraocular Pressure; Phenobarbital; Preopera | 1964 |
SKIN PIGMENTATION, CORNEAL AND LENS OPACITIES WITH PROLONGED CHLORPROMAZINE TREATMENT.
Topics: Biopsy; Cataract; Chlorpromazine; Cornea; Corneal Opacity; Drug Therapy; Electrocardiography; Eye Di | 1965 |
LENTICULAR AND CORNEAL OPACITIES DURING PHENOTHIAZINE THERAPY.
Topics: Cataract; Chlorpromazine; Corneal Opacity; Drug Therapy; Lens, Crystalline; Mental Disorders; Phenot | 1965 |
LENTICULAR OPACITIES WITH PROLONGED PHENOTHIAZINE THERAPY: A POTENTIAL HAZARD WITH ALL PHENOTHIAZINE DERIVATIVES.
Topics: Antipsychotic Agents; Cataract; Chlorpromazine; Drug Therapy; Fluphenazine; Phenothiazines; Prochlor | 1965 |
Effect of various agents on drug-induced opacities of the lens.
Topics: Animals; Cataract; Chlorpromazine; Epinephrine; Female; Hypoxia; Male; Mice; Morphine; Nikethamide; | 1967 |
[Ocular changes in chlorpromazine-induced melanosis].
Topics: Adult; Cataract; Chlorpromazine; Female; Humans; Male; Melanosis; Middle Aged | 1984 |
Opacities and thioridazine.
Topics: Cataract; Chlorpromazine; Humans; Thioridazine | 1983 |
Corneal and lenticular opacities in mentally retarded young adults treated with thioridazine and chlorpromazine.
Topics: Adolescent; Adult; Cataract; Child; Chlorpromazine; Corneal Opacity; Female; Humans; Institutionaliz | 1982 |
Asymmetric anterior segment changes induced by chlorpromazine.
Topics: Blepharoptosis; Cataract; Chlorpromazine; Conjunctival Diseases; Corneal Opacity; Eye Diseases; Huma | 1981 |
Chlorpromazine-induced refractile corneal deposits and cataract.
Topics: Antipsychotic Agents; Cataract; Chlorpromazine; Corneal Diseases; Female; Humans; Middle Aged | 1999 |
Are schizophrenia or antipsychotic drugs a risk factor for cataracts?
Topics: Adult; Age Distribution; Aged; Aged, 80 and over; Antipsychotic Agents; Cataract; Chlorpromazine; Co | 2000 |
Ocular adverse reactions to drugs.
Topics: Adrenal Cortex Hormones; Adult; Aged; Amblyopia; Cataract; Chloroquine; Chlorpromazine; Conjunctivit | 1977 |
[Iatrogenic cataract].
Topics: Cataract; Chlorpromazine; Humans; Iatrogenic Disease; Triparanol | 1975 |
Lens changes associated with long-term psychotropica therapy.
Topics: Adult; Cataract; Chlorpromazine; Female; Humans; Lens, Crystalline; Male; Mental Disorders; Psychotr | 1975 |
Deposits in the lens and cornea of the eye during long-term chlorpromazine medication.
Topics: Adult; Aged; Cataract; Chlorpromazine; Corneal Opacity; Female; Humans; Middle Aged; Schizophrenia; | 1976 |
The prevalence of the ocular side effects of chlorpromazine in the Tuscaloosa Veterans Administration patient population.
Topics: Adult; Aged; Cataract; Chlorpromazine; Cornea; Corneal Opacity; Corneal Stroma; Eye; Humans; Lens Ca | 1985 |
[Iatrogenic cataracts].
Topics: Aged; Anesthetics, Local; Anthelmintics; Azathioprine; Cataract; Chloroquine; Chlorpromazine; Dimeth | 1974 |
[Study of the aqueous humor after prolonged treatment with neuroleptics].
Topics: Aqueous Humor; Cataract; Chlorpromazine; Cornea; Eye Diseases; Humans; Time Factors | 1972 |
Total dosage of chlorpromazine and ocular opacities.
Topics: Cataract; Chlorpromazine; Corneal Opacity; Dose-Response Relationship, Drug; Humans; Schizophrenia | 1967 |
Long term evolution of the side-effect lens opacities induced by chlorpromazine prolonged therapy.
Topics: Cataract; Chlorpromazine; Female; Humans; Mental Disorders; Middle Aged; Pigmentation Disorders; Ski | 1971 |
Eye changes in connection with neuroleptic treatment especially concerning phenothiazines and thioxanthenes.
Topics: Adult; Age Factors; Aged; Cataract; Chlorpromazine; Cornea; Evaluation Studies as Topic; Eye Disease | 1971 |
[Ophthalmologic study of patients receiving psychotropic drugs].
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents; Bipolar Disorder; Cataract; Cerebrova | 1970 |
Toxic effects of phenothiazines on the eye.
Topics: Adult; Arsenic; Cataract; Chemical Phenomena; Chemistry; Chlorpromazine; Color Vision Defects; Conju | 1970 |
Acute reversible lens opacity: caused by drugs, cold, anoxia, asphyxia, stress, death and dehydration.
Topics: Animals; Asphyxia; Cataract; Cats; Chlorpromazine; Cricetinae; Death; Dehydration; Epinephrine; Eyel | 1970 |
Phenothiazines in ophthalmology.
Topics: Cataract; Chlorpromazine; Chorioretinitis; Eye Diseases; Humans; Melanins; Microscopy; Phenothiazine | 1967 |
The influence of the sympathetic nervous system on the action of drugs on the lens.
Topics: Animals; Blepharoptosis; Body Temperature; Cataract; Chlorpromazine; Female; Guanethidine; Imipramin | 1969 |
Experimental chlorpromazine cataracts.
Topics: Animals; Cataract; Chlorpromazine; Culture Techniques; Dialysis; Epithelium; Guinea Pigs; Lens, Crys | 1969 |
The ocular toxic findings with prolonged and high dosage chlorpromazine intake.
Topics: Adolescent; Adult; Aged; Cataract; Chlorpromazine; Eye Manifestations; Humans; Lacrimal Apparatus; M | 1965 |
Lenticular opacities induced in mice by chlorpromazine.
Topics: Animals; Cataract; Chlorpromazine; Epinephrine; Lens, Crystalline; Levorphanol; Mice; Phenoxybenzami | 1966 |
Ocular toxic changes associated with chlorpromazine and thioridazine.
Topics: Adolescent; Adult; Aged; Cataract; Chlorpromazine; Eye; Female; Fundus Oculi; Gonioscopy; Humans; In | 1966 |
Effect of lid closure in drug-induced experimental cataracts.
Topics: Animals; Cataract; Chlorpromazine; Epinephrine; Eyelids; Mice; Morphine; Occlusive Dressings | 1966 |
Ocular changes produced by chlorpromazine.
Topics: Adult; Aged; Cataract; Chlorpromazine; Corneal Opacity; Female; Humans; Male; Middle Aged; Ophthalmo | 1966 |
Ocular changes associated with chlorpromazine therapy. A preliminary report.
Topics: Adult; Aged; Cataract; Chlorpromazine; Corneal Opacity; Female; Glaucoma; Humans; Male; Middle Aged; | 1966 |