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chlorpromazine and Cataract, Membranous

chlorpromazine has been researched along with Cataract, Membranous in 48 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Research Excerpts

ExcerptRelevanceReference
"Chlorpromazine is a low potency "typical" antipsychotic agent used to treat schizophrenia."3.85Kerato-lenticular ocular deposits and visual impairment with prolonged chlorpromazine use: A case series. ( Gowda, GS; Hegde, A; Jaisoorya, TS; Narayanaswamy, JC; Shanbhag, V, 2017)
" We analyzed the prevalence of ocular side effects of chlorpromazine and found that the most prevalent side effect was anterior lens capsule dusting followed by corneal stromal pigment dusting."1.27The prevalence of the ocular side effects of chlorpromazine in the Tuscaloosa Veterans Administration patient population. ( Alexander, LJ; Bowerman, L; Thompson, LR, 1985)
" The risk of using chlorpromazine in moderate dosage is slight."1.26Deposits in the lens and cornea of the eye during long-term chlorpromazine medication. ( Faurbye, A; Kirk, L; Rasmussen, K, 1976)

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-199045 (93.75)18.7374
1990's1 (2.08)18.2507
2000's1 (2.08)29.6817
2010's1 (2.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gowda, GS1
Hegde, A1
Shanbhag, V1
Narayanaswamy, JC1
Jaisoorya, TS1
HARLEY, RD3
MISHLER, JE3
TOWNES, CD1
MANN, SH1
LOW, H1
AGARWAL, LP1
GUPTA, RB1
MALIK, SR1
CESA, R1
MARTINELLI, G1
GREINER, AC1
BERRY, K1
BHATNAGAR, BS1
MASSEY, LW1
BARSA, JA1
NEWTON, JC1
SAUNDERS, JC1
MARGOLIS, LH1
GOBLE, JL1
Weinstock, M2
Scott, JD1
Schönthaler, M1
Westlin, WF1
Gualtieri, CT1
Lefler, WH1
Guimond, M1
Staye, JI1
Deluise, VP1
Flynn, JT1
Leung, AT1
Cheng, AC1
Chan, WM1
Lam, DS1
Ruigómez, A1
García Rodríguez, LA1
Dev, VJ1
Arellano, F1
Raniwala, J1
Crews, SJ1
Koch, HR2
Hockwin, O2
Setogawa, T1
Tamai, A1
Matsuura, H1
Ogura, C1
Rasmussen, K1
Kirk, L1
Faurbye, A1
Alexander, LJ1
Bowerman, L1
Thompson, LR1
Gehring, PJ1
Barg, TsM1
Verrey, F1
Cuendet, JF1
Nouri, A1
Marzulli, FN1
Appleton, WS1
Shader, RI1
DiMascio, A1
Abakumov, VM1
Vikhliaev, IuI1
Bernstein, HN1
Buffaloe, WJ1
Johnson, AW1
Sandifer, MG1
Baron, JB1
Rivoalan, Y1
Morel, P1
Edler, K2
Gottfries, CG1
Haslund, J1
Ravn, J1
Gol'dovskaia, IL1
Boet, DJ1
Fraunfelder, FT2
Burns, RP2
Siddall, JR3
Marshall, AS1
Howard, RO1
McDonald, CJ1
Dunn, B1
Creasey, WA1
Smith, AA1
Gavitt, JA1
Karmin, M1
Dencker, SJ1
Enoksson, P1

Reviews

6 reviews available for chlorpromazine and Cataract, Membranous

ArticleYear
The cataractogenic activity of chemical agents.
    CRC critical reviews in toxicology, 1971, Volume: 1, Issue:1

    Topics: Adrenal Cortex Hormones; Alkylating Agents; Aniline Compounds; Carbohydrates; Cataract; Chemical Phe

1971
[Eye complications during use of various medicinal substances with general effects (review of the literature)].
    Oftalmologicheskii zhurnal, 1969, Volume: 24, Issue:8

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Allopurinol; Anti-Bacterial Agents; Antimalari

1969
Ocular side effects of drugs.
    Food and cosmetics toxicology, 1968, Volume: 6, Issue:2

    Topics: Animals; Cataract; Chlorpromazine; Dogs; Drug-Related Side Effects and Adverse Reactions; Electroret

1968
Ocular (pigmentary) effects of psychotropic drugs.
    Connecticut medicine, 1970, Volume: 34, Issue:1

    Topics: Cataract; Chlorpromazine; Corneal Opacity; Humans; Phenothiazines; Pigmentation Disorders; Tranquili

1970
[The metabolism of psychotropic drugs (phenothiazine and iminodibenzyl derivatives)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1970, Volume: 70, Issue:3

    Topics: Animals; Antidepressive Agents; Cataract; Chemical Phenomena; Chemistry; Chlorpromazine; Dogs; Human

1970
Some iatrogenic ocular diseases from systemically administered drugs.
    International ophthalmology clinics, 1970,Fall, Volume: 10, Issue:3

    Topics: Animals; Cataract; Cats; Chemical Phenomena; Chemistry; Chloramphenicol; Chloroquine; Chlorpromazine

1970

Other Studies

42 other studies available for chlorpromazine and Cataract, Membranous

ArticleYear
Kerato-lenticular ocular deposits and visual impairment with prolonged chlorpromazine use: A case series.
    Asian journal of psychiatry, 2017, Volume: 25

    Topics: Adult; Antipsychotic Agents; Cataract; Chlorpromazine; Cornea; Female; Humans; Lens Capsule, Crystal

2017
The use of chlorpromazine in cataract surgery; a preliminary report.
    American journal of ophthalmology, 1957, Volume: 43, Issue:5

    Topics: Cataract; Cataract Extraction; Chlorpromazine; Lens, Crystalline

1957
Intravenous sedation in cataract surgery.
    American journal of ophthalmology, 1958, Volume: 46, Issue:2

    Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Cataract; Cataract Extraction; Chlorpromazine; Huma

1958
Ataractic and antiemetic drugs in cataract surgery.
    American journal of ophthalmology, 1959, Volume: 47, Issue:2

    Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Antiemetics; Cataract; Cataract Extraction; Chlorpr

1959
The effects of promazines on mitochondrial adenosine triphosphatase reactions.
    Biochimica et biophysica acta, 1959, Volume: 32, Issue:1

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Cataract; Chlorpromazine; Humans; Phenothiazines;

1959
Ataractic and anti-emetic drugs in cataract surgery.
    Transactions of the American Ophthalmological Society, 1958, Volume: 56

    Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Antiemetics; Cataract; Cataract Extraction; Chlorpr

1958
Drug administration in cataract surgery.
    The British journal of ophthalmology, 1959, Volume: 43, Issue:5

    Topics: Acetazolamide; Cataract; Cataract Extraction; Chlorpromazine; Curare; Humans; Lens, Crystalline

1959
[THE USE OF CURARE IN CATARACT SURGERY. CLINICO-STATISTICAL CONTRIBUTION].
    Annali di ottalmologia e clinica oculistica, 1963, Volume: 89

    Topics: Anesthesia; Anesthesiology; Cataract; Cataract Extraction; Chlorpromazine; Curare; Hibernation; Huma

1963
SKIN PIGMENTATION AND CORNEAL AND LENS OPACITIES WITH PROLONGED CHLORPROMAZINE THERAPY.
    Canadian Medical Association journal, 1964, Mar-14, Volume: 90

    Topics: Cataract; Chlorpromazine; Cornea; Corneal Opacity; Female; Humans; Lens, Crystalline; Melanins; Opht

1964
INTRA-OCULAR PRESSURE IN CATARACT SURGERY.
    Indian journal of medical sciences, 1964, Volume: 18

    Topics: Cataract; Cataract Extraction; Chlorpromazine; Humans; Intraocular Pressure; Phenobarbital; Preopera

1964
SKIN PIGMENTATION, CORNEAL AND LENS OPACITIES WITH PROLONGED CHLORPROMAZINE TREATMENT.
    Canadian Medical Association journal, 1965, Jan-23, Volume: 92

    Topics: Biopsy; Cataract; Chlorpromazine; Cornea; Corneal Opacity; Drug Therapy; Electrocardiography; Eye Di

1965
LENTICULAR AND CORNEAL OPACITIES DURING PHENOTHIAZINE THERAPY.
    JAMA, 1965, Jul-05, Volume: 193

    Topics: Cataract; Chlorpromazine; Corneal Opacity; Drug Therapy; Lens, Crystalline; Mental Disorders; Phenot

1965
LENTICULAR OPACITIES WITH PROLONGED PHENOTHIAZINE THERAPY: A POTENTIAL HAZARD WITH ALL PHENOTHIAZINE DERIVATIVES.
    JAMA, 1965, Jul-05, Volume: 193

    Topics: Antipsychotic Agents; Cataract; Chlorpromazine; Drug Therapy; Fluphenazine; Phenothiazines; Prochlor

1965
Effect of various agents on drug-induced opacities of the lens.
    Experimental eye research, 1967, Volume: 6, Issue:4

    Topics: Animals; Cataract; Chlorpromazine; Epinephrine; Female; Hypoxia; Male; Mice; Morphine; Nikethamide;

1967
[Ocular changes in chlorpromazine-induced melanosis].
    Klinika oczna, 1984, Volume: 86, Issue:11

    Topics: Adult; Cataract; Chlorpromazine; Female; Humans; Male; Melanosis; Middle Aged

1984
Opacities and thioridazine.
    The American journal of psychiatry, 1983, Volume: 140, Issue:5

    Topics: Cataract; Chlorpromazine; Humans; Thioridazine

1983
Corneal and lenticular opacities in mentally retarded young adults treated with thioridazine and chlorpromazine.
    The American journal of psychiatry, 1982, Volume: 139, Issue:9

    Topics: Adolescent; Adult; Cataract; Child; Chlorpromazine; Corneal Opacity; Female; Humans; Institutionaliz

1982
Asymmetric anterior segment changes induced by chlorpromazine.
    Annals of ophthalmology, 1981, Volume: 13, Issue:8

    Topics: Blepharoptosis; Cataract; Chlorpromazine; Conjunctival Diseases; Corneal Opacity; Eye Diseases; Huma

1981
Chlorpromazine-induced refractile corneal deposits and cataract.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1999, Volume: 117, Issue:12

    Topics: Antipsychotic Agents; Cataract; Chlorpromazine; Corneal Diseases; Female; Humans; Middle Aged

1999
Are schizophrenia or antipsychotic drugs a risk factor for cataracts?
    Epidemiology (Cambridge, Mass.), 2000, Volume: 11, Issue:6

    Topics: Adult; Age Distribution; Aged; Aged, 80 and over; Antipsychotic Agents; Cataract; Chlorpromazine; Co

2000
Ocular adverse reactions to drugs.
    The Practitioner, 1977, Volume: 219, Issue:1309

    Topics: Adrenal Cortex Hormones; Adult; Aged; Amblyopia; Cataract; Chloroquine; Chlorpromazine; Conjunctivit

1977
[Iatrogenic cataract].
    Therapie der Gegenwart, 1975, Volume: 114, Issue:9

    Topics: Cataract; Chlorpromazine; Humans; Iatrogenic Disease; Triparanol

1975
Lens changes associated with long-term psychotropica therapy.
    Yonago acta medica, 1975, Volume: 19, Issue:2

    Topics: Adult; Cataract; Chlorpromazine; Female; Humans; Lens, Crystalline; Male; Mental Disorders; Psychotr

1975
Deposits in the lens and cornea of the eye during long-term chlorpromazine medication.
    Acta psychiatrica Scandinavica, 1976, Volume: 53, Issue:1

    Topics: Adult; Aged; Cataract; Chlorpromazine; Corneal Opacity; Female; Humans; Middle Aged; Schizophrenia;

1976
The prevalence of the ocular side effects of chlorpromazine in the Tuscaloosa Veterans Administration patient population.
    Journal of the American Optometric Association, 1985, Volume: 56, Issue:11

    Topics: Adult; Aged; Cataract; Chlorpromazine; Cornea; Corneal Opacity; Corneal Stroma; Eye; Humans; Lens Ca

1985
[Iatrogenic cataracts].
    Medizinische Klinik, 1974, Oct-18, Volume: 69, Issue:42

    Topics: Aged; Anesthetics, Local; Anthelmintics; Azathioprine; Cataract; Chloroquine; Chlorpromazine; Dimeth

1974
[Study of the aqueous humor after prolonged treatment with neuroleptics].
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1972, Volume: 165, Issue:3-4

    Topics: Aqueous Humor; Cataract; Chlorpromazine; Cornea; Eye Diseases; Humans; Time Factors

1972
Total dosage of chlorpromazine and ocular opacities.
    The American journal of psychiatry, 1967, Volume: 124, Issue:2

    Topics: Cataract; Chlorpromazine; Corneal Opacity; Dose-Response Relationship, Drug; Humans; Schizophrenia

1967
Long term evolution of the side-effect lens opacities induced by chlorpromazine prolonged therapy.
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1971, Volume: 12, Issue:1

    Topics: Cataract; Chlorpromazine; Female; Humans; Mental Disorders; Middle Aged; Pigmentation Disorders; Ski

1971
Eye changes in connection with neuroleptic treatment especially concerning phenothiazines and thioxanthenes.
    Acta psychiatrica Scandinavica, 1971, Volume: 47, Issue:4

    Topics: Adult; Age Factors; Aged; Cataract; Chlorpromazine; Cornea; Evaluation Studies as Topic; Eye Disease

1971
[Ophthalmologic study of patients receiving psychotropic drugs].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1970, Volume: 70, Issue:5

    Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents; Bipolar Disorder; Cataract; Cerebrova

1970
Toxic effects of phenothiazines on the eye.
    Documenta ophthalmologica. Advances in ophthalmology, 1970, Jul-24, Volume: 28, Issue:1

    Topics: Adult; Arsenic; Cataract; Chemical Phenomena; Chemistry; Chlorpromazine; Color Vision Defects; Conju

1970
Acute reversible lens opacity: caused by drugs, cold, anoxia, asphyxia, stress, death and dehydration.
    Experimental eye research, 1970, Volume: 10, Issue:1

    Topics: Animals; Asphyxia; Cataract; Cats; Chlorpromazine; Cricetinae; Death; Dehydration; Epinephrine; Eyel

1970
Phenothiazines in ophthalmology.
    International ophthalmology clinics, 1967,Spring, Volume: 7, Issue:1

    Topics: Cataract; Chlorpromazine; Chorioretinitis; Eye Diseases; Humans; Melanins; Microscopy; Phenothiazine

1967
The influence of the sympathetic nervous system on the action of drugs on the lens.
    The Journal of pharmacology and experimental therapeutics, 1969, Volume: 166, Issue:1

    Topics: Animals; Blepharoptosis; Body Temperature; Cataract; Chlorpromazine; Female; Guanethidine; Imipramin

1969
Experimental chlorpromazine cataracts.
    Investigative ophthalmology, 1969, Volume: 8, Issue:4

    Topics: Animals; Cataract; Chlorpromazine; Culture Techniques; Dialysis; Epithelium; Guinea Pigs; Lens, Crys

1969
The ocular toxic findings with prolonged and high dosage chlorpromazine intake.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1965, Volume: 74, Issue:4

    Topics: Adolescent; Adult; Aged; Cataract; Chlorpromazine; Eye Manifestations; Humans; Lacrimal Apparatus; M

1965
Lenticular opacities induced in mice by chlorpromazine.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1966, Volume: 75, Issue:1

    Topics: Animals; Cataract; Chlorpromazine; Epinephrine; Lens, Crystalline; Levorphanol; Mice; Phenoxybenzami

1966
Ocular toxic changes associated with chlorpromazine and thioridazine.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1966, Volume: 1, Issue:3

    Topics: Adolescent; Adult; Aged; Cataract; Chlorpromazine; Eye; Female; Fundus Oculi; Gonioscopy; Humans; In

1966
Effect of lid closure in drug-induced experimental cataracts.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1966, Volume: 76, Issue:4

    Topics: Animals; Cataract; Chlorpromazine; Epinephrine; Eyelids; Mice; Morphine; Occlusive Dressings

1966
Ocular changes produced by chlorpromazine.
    Acta ophthalmologica, 1966, Volume: 44, Issue:3

    Topics: Adult; Aged; Cataract; Chlorpromazine; Corneal Opacity; Female; Humans; Male; Middle Aged; Ophthalmo

1966
Ocular changes associated with chlorpromazine therapy. A preliminary report.
    Acta ophthalmologica, 1966, Volume: 44, Issue:3

    Topics: Adult; Aged; Cataract; Chlorpromazine; Corneal Opacity; Female; Glaucoma; Humans; Male; Middle Aged;

1966