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chlorpromazine and Cardiovascular Stroke

chlorpromazine has been researched along with Cardiovascular Stroke in 44 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Research Excerpts

ExcerptRelevanceReference
"The intravenous administration of chlorpromazine in 12 patients with acute myocardial infarction and altered pump function was followed by a significant reduction in systemic vascular resistance (28."7.65Hemodynamic effects of chlorpromazine in patients with acute myocardial infarction and pump failure. ( Elkayam, U; Geller, E; Laniado, S; Rotmensch, HH; Terdiman, R, 1977)
"The intravenous administration of chlorpromazine in 12 patients with acute myocardial infarction and altered pump function was followed by a significant reduction in systemic vascular resistance (28."3.65Hemodynamic effects of chlorpromazine in patients with acute myocardial infarction and pump failure. ( Elkayam, U; Geller, E; Laniado, S; Rotmensch, HH; Terdiman, R, 1977)
"Chlorpromazine pretreatment was associated with significant (p less than 0."1.27Effect of chlorpromazine on myocardial damage in the calcium paradox. ( Rabkin, SW, 1987)
"Chlorpromazine displays a stronger antistress action than does trioxazine, but the available data justify recommending both these drugs for the treatment of patients with myocardial infarction."1.25[Changes in the glucocorticoid function of the adrenal cortex in patients with myocardial infarct treated with trioxazine and aminazine]. ( Miloslavskiĭ, IM; Oslopov, VN, 1975)

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-199042 (95.45)18.7374
1990's1 (2.27)18.2507
2000's0 (0.00)29.6817
2010's1 (2.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Eguchi, S1
Takefuji, M1
Sakaguchi, T1
Ishihama, S1
Mori, Y1
Tsuda, T1
Takikawa, T1
Yoshida, T1
Ohashi, K1
Shimizu, Y1
Hayashida, R1
Kondo, K1
Bando, YK1
Ouchi, N1
Murohara, T1
PAULY, R1
BULLE, PH1
ARORA, RB1
SHARMA, PL1
GROSS, R1
SAMBHI, MP1
WEIL, MH1
UDHOJI, VN1
ROSOFF, L1
Neĭmark, II1
Fornel', MB1
Slezák, J3
Tribulová, N2
Gabauer, I2
Ziegelhöffer, A2
Styk, J1
Elkayam, U2
Frishman, W1
Ueda, K1
Mifune, J1
Inoue, H1
Sugiura, M1
Murakami, M1
Nunnally, RL1
Bottomley, PA1
Maroko, PR1
Born, GV3
Foster, CS1
Wehmeier, A1
Rotmensch, HH1
Terdiman, R1
Geller, E1
Laniado, S1
Galen, RS1
Sudakov, KV1
Miloslavskiĭ, IM1
Oslopov, VN1
Yanagisawa, H1
Rabkin, SW1
Kiricuta, IC1
Schmitt, WG1
Beyer, HK1
Wood, M1
Holec, V1
Cheung, JY1
Bonventre, JV1
Malis, CD1
Leaf, A1
Ceremuzyński, L2
Dłuzniewski, M2
Krzemińska-Pakuła, M1
Nartowicz, E1
Zebrowski, A1
Burduk, P1
Budaj, A2
Bednarz, B2
Jurgiel, R1
Grochowicz, U1
Kłoś, J1
Clauss, RH1
Ray, JF1
Gratsianskiĭ, NA1
Soroff, HS1
Cloutier, CT1
Birtwell, WC1
Begley, LA1
Messer, JV1
Kounis, NG1
Kishenets, VA1
Gunnar, RM1
Loeb, HS1
Gvatua, NA1
Kravtsov, VL1
Tsyganii, AA1
Pomerantsev, IuV1
Ianovskii, AD1
Pevzner, IIa2
Kagiev, NM1
Turkiewicz, R1
Haragus, S1
Uza, G1
Crisnic, I1
Missits, P1
Grishaeva, LM1
Feola, M1
Haiderer, O1
Kennedy, JH1
Flaherty, GN1
Gulotta, SJ1
Ikram, H1
Orchard, RT1
Read, SE1
Dietzman, RH1
Lillehei, RC1

Reviews

5 reviews available for chlorpromazine and Cardiovascular Stroke

ArticleYear
Cardiovascular effects of phenothiazines.
    American heart journal, 1980, Volume: 100, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Cardiopulmonary Bypass; Cardi

1980
[Possibilities of phosphorus 31 spectroscopy in assessing the therapeutic effects on cellular energy metabolism of the myocardium].
    Herz, 1989, Volume: 14, Issue:4

    Topics: Acebutolol; Cardioplegic Solutions; Chlorpromazine; Energy Metabolism; Humans; Magnetic Resonance Sp

1989
Plasma drug binding: implications for anesthesiologists.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:7

    Topics: Age Factors; Alfentanil; Alprenolol; Anesthesia; Anesthetics; Blood Proteins; Bupivacaine; Burns; Ca

1986
Calcium and ischemic injury.
    The New England journal of medicine, 1986, Jun-26, Volume: 314, Issue:26

    Topics: Animals; Calcium; Calcium Channel Blockers; Chlorpromazine; Cytosol; Extracellular Space; Homeostasi

1986
Pharmacologic assistance to the failing circulation.
    Surgery, gynecology & obstetrics, 1968, Volume: 126, Issue:3

    Topics: Adenosine Triphosphatases; Aminophylline; Angiotensin II; Blood Gas Analysis; Blood Pressure; Cardia

1968

Trials

1 trial available for chlorpromazine and Cardiovascular Stroke

ArticleYear
Use of drugs in cardiogenic shock due to acute myocardial infarction.
    Circulation, 1972, Volume: 45, Issue:5

    Topics: Acute Disease; Blood Pressure; Central Venous Pressure; Chlorpromazine; Clinical Trials as Topic; De

1972

Other Studies

38 other studies available for chlorpromazine and Cardiovascular Stroke

ArticleYear
Cardiomyocytes capture stem cell-derived, anti-apoptotic microRNA-214 via clathrin-mediated endocytosis in acute myocardial infarction.
    The Journal of biological chemistry, 2019, 08-02, Volume: 294, Issue:31

    Topics: Acute Disease; Animals; Antagomirs; Apoptosis; Cell Hypoxia; Cells, Cultured; Chlorpromazine; Clathr

2019
[New data on the dangers of therapy with largactil; a case of myocardial infarct in the course of an ambulant treatment].
    Journal de medecine de Bordeaux et du Sud-Ouest, 1954, Volume: 131, Issue:6

    Topics: Autonomic Agents; Chlorpromazine; Myocardial Infarction

1954
Chlorpromazine and reserpine prevention of myocardial damage by histamine and serotonin.
    Science (New York, N.Y.), 1957, Jul-05, Volume: 126, Issue:3262

    Topics: Chlorpromazine; Histamine; Myocardial Infarction; Myocardium; Reserpine; Serotonin

1957
Effectiveness of some anticonvulsant drugs in ventricular tachycardia resulting from acute myocardial infarction in the dog.
    The Indian journal of medical research, 1958, Volume: 46, Issue:6

    Topics: Acetazolamide; Animals; Anticonvulsants; Chlorpromazine; Dogs; Humans; Myocardial Infarction; Primid

1958
[SHORT DIRECTIONS FOR THE TREATMENT OF A RECENT MYOCARDIAL INFARCT].
    Deutsche medizinische Wochenschrift (1946), 1964, Oct-30, Volume: 89

    Topics: Anticoagulants; Antipsychotic Agents; Cardiac Glycosides; Chlorpromazine; Codeine; Dipyridamole; Dru

1964
EFFECT OF PRESSOR AMINES ON CARDIAC OUTPUT IN PATIENTS WITH ACUTE HYPOTENSION.
    Circulation, 1964, Volume: 30

    Topics: Amines; Barbiturates; Blood Pressure; Cardiac Output; Chlorpromazine; Dehydration; Drug Therapy; Dye

1964
[Treatment of coronary insufficiecy by applying retrosternal potentiated block].
    Sovetskaia meditsina, 1966, Volume: 29, Issue:11

    Topics: Adult; Aged; Alcohols; Angina Pectoris; Aniline Compounds; Autonomic Nerve Block; Bis-Trimethylammon

1966
[Manifestation of the oxygen paradox during perfusion of the ischemic myocardium and its prevention by chlorpromazine and protease inhibition].
    Bratislavske lekarske listy, 1984, Volume: 81, Issue:3

    Topics: Animals; Aprotinin; Calcium; Chlorpromazine; Coronary Circulation; Dogs; Myocardial Infarction; Myoc

1984
Influence of vasodilator therapy on prognosis of acute myocardial infarction in the aged patients. A comparative study between vasodilator-treated group and group treated without vasodilator.
    Japanese heart journal, 1980, Volume: 21, Issue:1

    Topics: Age Factors; Aged; Chlorpromazine; Female; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate

1980
Assessment of pharmacological treatment of myocardial infarction by phosphorus-31 NMR with surface coils.
    Science (New York, N.Y.), 1981, Jan-09, Volume: 211, Issue:4478

    Topics: Animals; Chlorpromazine; Coronary Circulation; Disease Models, Animal; Magnetic Resonance Spectrosco

1981
Experimental infarction studies.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1980, Volume: 3, Issue:1-2

    Topics: Animals; Chlorpromazine; Dogs; Heart Rate; Ibuprofen; Morphine; Myocardial Infarction; Myocardium; P

1980
Possible role for chlorpromazine in protection against myocardial infarction.
    Lancet (London, England), 1979, Apr-14, Volume: 1, Issue:8120

    Topics: Anticoagulants; Chlorpromazine; Coronary Disease; Hemolysis; Humans; Myocardial Infarction; Platelet

1979
Chlorpromazine in prophylaxis of myocardial infarction.
    Lancet (London, England), 1979, Jun-09, Volume: 1, Issue:8128

    Topics: Chlorpromazine; Humans; Mitochondria, Heart; Myocardial Infarction

1979
Chlorpromazine in prophylaxis of myocardial infarction.
    Lancet (London, England), 1979, Jun-30, Volume: 1, Issue:8131

    Topics: Chlorpromazine; Hemolysis; Humans; Myocardial Infarction

1979
Inhibition of platelet thrombus formation by chlorpromazine acting to diminish haemolysis.
    Nature, 1979, Nov-08, Volume: 282, Issue:5735

    Topics: Adenosine Diphosphate; Blood Coagulation; Chlorpromazine; Depression, Chemical; Dose-Response Relati

1979
Hemodynamic effects of chlorpromazine in patients with acute myocardial infarction and pump failure.
    Chest, 1977, Volume: 72, Issue:5

    Topics: Acute Disease; Aged; Blood Pressure; Cardiac Output; Chlorpromazine; Female; Heart Failure; Heart Ra

1977
The enzyme diagnosis of myocardial infarction.
    Human pathology, 1975, Volume: 6, Issue:2

    Topics: Angiography; Aspartate Aminotransferases; Cardiac Surgical Procedures; Chlorpromazine; Clinical Enzy

1975
[Neurophysiological mechanisms of arterial hypertension in experimental emotional stress].
    Vestnik Akademii meditsinskikh nauk SSSR, 1975, Issue:8

    Topics: Animals; Blood Pressure; Brain; Chlorpromazine; Electric Stimulation; Humans; Hypothalamus; Models,

1975
[Changes in the glucocorticoid function of the adrenal cortex in patients with myocardial infarct treated with trioxazine and aminazine].
    Kardiologiia, 1975, Volume: 15, Issue:8

    Topics: 11-Hydroxycorticosteroids; Adaptation, Physiological; Adrenal Cortex; Adrenal Glands; Chlorpromazine

1975
Acute myocardial infarction improved by neuroleptic analgesic therapy.
    Southern medical journal, 1990, Volume: 83, Issue:7

    Topics: Analgesia; Blood Pressure; Chlorpromazine; Coronary Vasospasm; Drug Combinations; Electrocardiograph

1990
Effect of chlorpromazine on myocardial damage in the calcium paradox.
    Journal of cardiovascular pharmacology, 1987, Volume: 9, Issue:4

    Topics: Animals; Calcium; Chlorpromazine; Female; Myocardial Infarction; Myocardium; Necrosis; Rabbits

1987
Diminution of "reperfusion injury" in reperfused ischemic myocardium by phenothiazines. A quantitative morphological study.
    General physiology and biophysics, 1987, Volume: 6, Issue:5

    Topics: Adenine Nucleotides; Animals; Chlorpromazine; Dogs; Female; Ischemia; Lactates; Male; Microscopy, El

1987
[Treatment of the acute phase of myocardial infarction with a lytic cocktail (morphine, chlorpromazine and promethazine)].
    Kardiologia polska, 1987, Volume: 30, Issue:2

    Topics: Aged; Chlorpromazine; Drug Combinations; Female; Humans; Male; Middle Aged; Morphine; Myocardial Inf

1987
[Effect of treatment of patients with acute myocardial infarction with a lytic mixture (morphine-chlorpromazine-promethazine) on catecholamine excretion].
    Kardiologia polska, 1987, Volume: 30, Issue:3

    Topics: Adult; Aged; Chlorpromazine; Drug Therapy, Combination; Epinephrine; Female; Humans; Male; Middle Ag

1987
[Use of adrenergic alpha receptor blockaders in patients with myocardial infarct in the state of shock].
    Kardiologiia, 1970, Volume: 10, Issue:9

    Topics: Adrenergic alpha-Antagonists; Aged; Blood Pressure; Central Venous Pressure; Chlorpromazine; Dextran

1970
External counterpulsation. Management of cardiogenic shock after myocardial infarction.
    JAMA, 1974, Sep-09, Volume: 229, Issue:11

    Topics: Aged; Assisted Circulation; Blood Pressure; Cardiac Catheterization; Chlorpromazine; Digitalis; Eval

1974
Persistent hiccuping in acute myocardial infarction--report of a case.
    Irish medical journal, 1974, Dec-21, Volume: 67, Issue:24

    Topics: Aged; Chlorpromazine; Hiccup; Humans; Male; Myocardial Infarction; Prognosis

1974
[Effect of aminazine on renal hemodynamics in patients with myocardial infarct].
    Vrachebnoe delo, 1974, Issue:1

    Topics: Adult; Aged; Chlorpromazine; Humans; Kidney; Middle Aged; Myocardial Infarction; Regional Blood Flow

1974
[Some aspects of the use of prolonged neuroplegia in treating acute myocardial infarct].
    Kardiologiia, 1973, Volume: 13, Issue:4

    Topics: Acute Disease; Aminopyrine; Analgesics; Anti-Arrhythmia Agents; Anticoagulants; Autonomic Agents; Be

1973
[Effect of aminazin during acute myocardial infarct on the contractile capacity of the myocardium in a remote period].
    Terapevticheskii arkhiv, 1971, Volume: 43, Issue:9

    Topics: Chlorpromazine; Electrocardiography; Evaluation Studies as Topic; Heart; Humans; Myocardial Infarcti

1971
[Myocardial infarct following ethanol and chlorpromazine poisoning].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1971, Nov-01, Volume: 24, Issue:21

    Topics: Alcoholic Intoxication; Chlorpromazine; Drug Synergism; Electrocardiography; Humans; Male; Middle Ag

1971
The effect of chlorpromazine on platelet adhesiveness and extraction of oxygen in the tissues.
    Pathologia Europaea, 1971, Volume: 6, Issue:4

    Topics: Arteriosclerosis; Blood Pressure Determination; Chlorpromazine; Coronary Disease; Humans; Myocardial

1971
[Use of alpha-adrenolytic drugs in the treatment of myocardial infarct].
    Kardiologiia, 1971, Volume: 11, Issue:11

    Topics: Biliary Tract Diseases; Cerebrovascular Disorders; Chlorpromazine; Female; Humans; Male; Myocardial

1971
Experimental graded "pump failure" of the left ventricle.
    The Journal of surgical research, 1971, Volume: 11, Issue:7

    Topics: Animals; Aorta, Thoracic; Blood Flow Velocity; Blood Pressure; Carbon Dioxide; Cardiac Output; Cardi

1971
Deaths amongst asthmatics in Tasmania, 1964-1966.
    The Medical journal of Australia, 1970, May-30, Volume: 1, Issue:22

    Topics: Adolescent; Adult; Aerosols; Aged; Aminophylline; Asthma; Australia; Autopsy; Child; Child, Preschoo

1970
Chlorpromazine in the treatment of cardiogenic shock.
    American heart journal, 1970, Volume: 80, Issue:4

    Topics: Acute Disease; Cardiac Output; Cardiac Surgical Procedures; Chlorpromazine; Humans; Myocardial Infar

1970
Intractable hiccuping in acute myocardial infarction.
    British medical journal, 1971, May-29, Volume: 2, Issue:5760

    Topics: Acute Disease; Aged; Chlorpromazine; Hiccup; Humans; Injections, Intramuscular; Lidocaine; Male; Myo

1971
The treatment of cardiogenic shock. IV. The use of phenoxybenzamine and chlorpromazine.
    American heart journal, 1968, Volume: 75, Issue:1

    Topics: Blood Pressure; Cardiac Output; Chlorpromazine; Humans; Myocardial Infarction; Phenoxybenzamine; Uri

1968