chlorpromazine has been researched along with Carcinoma, Ehrlich Tumor in 15 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Carcinoma, Ehrlich Tumor: A transplantable, poorly differentiated malignant tumor which appeared originally as a spontaneous breast carcinoma in a mouse. It grows in both solid and ascitic forms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chlorpromazine was found to inhibit transcription at the step of initiation, not elongation." | 1.28 | Inhibitory action of phospholipid-interacting drugs on transcription initiation in a nuclear extract of Ehrlich ascites tumor cells. ( Hirai, H; Natori, S; Sekimizu, K, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (66.67) | 18.7374 |
| 1990's | 4 (26.67) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lialiaris, TS | 1 |
| Papachristou, F | 1 |
| Mourelatos, C | 1 |
| Simopoulou, M | 1 |
| BICKIS, IJ | 1 |
| QUASTEL, JH | 1 |
| SCHELLENBERG, H | 1 |
| Dalmark, M | 1 |
| Hoffmann, EK | 1 |
| Shenoy, MA | 1 |
| Biaglow, JE | 1 |
| Varnes, ME | 1 |
| Hetzel, FW | 1 |
| Bertsche, U | 1 |
| Lialiaris, T | 1 |
| Pantazaki, A | 1 |
| Sivridis, E | 1 |
| Mourelatos, D | 1 |
| Alvarez, J | 1 |
| Montero, M | 1 |
| García-Sancho, J | 1 |
| Hirai, H | 1 |
| Natori, S | 1 |
| Sekimizu, K | 1 |
| Rao, KR | 1 |
| Suzuki, T | 1 |
| Abiko, M | 1 |
| Kohno, H | 1 |
| Ohkubo, Y | 1 |
| Kubodera, A | 1 |
| Kuramochi, H | 1 |
| Takahashi, K | 1 |
| Takeuchi, T | 1 |
| Satomi, N | 1 |
| Sakurai, A | 1 |
| Haranaka, R | 1 |
| Haranaka, K | 1 |
| Hilz, H | 1 |
| Jarmers, G | 1 |
| Crifò, C | 1 |
| Bozzi, A | 1 |
| Mondoví, B | 1 |
| Strom, R | 1 |
15 other studies available for chlorpromazine and Carcinoma, Ehrlich Tumor
| Article | Year |
|---|---|
Antineoplastic and cytogenetic effects of chlorpromazine on human lymphocytes in vitro and on Ehrlich ascites tumor cells in vivo.
Topics: Animals; Antineoplastic Agents; Caffeine; Carcinoma, Ehrlich Tumor; Cell Cycle; Cell Proliferation; | 2009 |
EFFECTS OF METABOLIC INHIBITORS ON ENERGY METABOLISM OF EHRLICH ASCITES CARCINOMA CELLS.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Ascites; Azo Compounds; Carbon Isotopes; Car | 1965 |
[Effect of chlorpromazine and imipramine on the respiration and anaerobic glycolysis of mastocytoma P-815 and Ehrlich ascites tumor].
Topics: Animals; Carbohydrate Metabolism; Carbohydrates; Carcinoma, Ehrlich Tumor; Chlorpromazine; Glycolysi | 1961 |
Doxorubicin (Adriamycin) transport in Ehrlich ascites tumour cells: comparison with transport in human red blood cells.
Topics: 1-Octanol; 4-Chloromercuribenzenesulfonate; Adsorption; Animals; Carcinoma, Ehrlich Tumor; Cell Memb | 1983 |
Inhibition of cultured human tumor cell oxygen utilization by chlorpromazine.
Topics: Aerobiosis; Anaerobiosis; Animals; Carcinoma, Ehrlich Tumor; Cells, Cultured; Chlorpromazine; Cricet | 1983 |
Induction and repair of X-ray damage in mammalian cell cultures treated with membrane-active drugs.
Topics: Adenosine Triphosphate; Animals; Carcinoma, Ehrlich Tumor; Cell Membrane; Cell Survival; Cells, Cult | 1984 |
Chlorpromazine-induced damage on nucleic acids: a combined cytogenetic and biochemical study.
Topics: Animals; Bacteriophage lambda; Caffeine; Carcinoma, Ehrlich Tumor; Cells, Cultured; Chlorpromazine; | 1992 |
Cytochrome P-450 may link intracellular Ca2+ stores with plasma membrane Ca2+ influx.
Topics: Animals; Biological Transport; Blood Platelets; Calcium; Carcinoma, Ehrlich Tumor; Cell Membrane; Ce | 1991 |
Inhibitory action of phospholipid-interacting drugs on transcription initiation in a nuclear extract of Ehrlich ascites tumor cells.
Topics: Adenoviruses, Human; Animals; Carcinoma, Ehrlich Tumor; Cell Nucleus; Chlorpromazine; HeLa Cells; Hu | 1991 |
Response of Ehrlich carcinoma and the small intestine of mouse to combined treatment with chlorpromazine and X-rays.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Survival; Chlorpromazine; Combined Modality Therapy; Drug Sc | 1991 |
Studies on the 67Ga uptake mechanism by Ehrlich ascites tumor cells.
Topics: Animals; Calcium Radioisotopes; Carcinoma, Ehrlich Tumor; Chlorpromazine; Depression, Chemical; Gall | 1986 |
Tumor cell permeability to peplomycin.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Carcinoma, Ehrlich Tumor; Chlorpromazine; Chromatog | 1989 |
Preventive effects of several chemicals against lethality of recombinant human tumor necrosis factor.
Topics: Animals; Blood; Carcinoma, Ehrlich Tumor; Chlorpromazine; Cortisone; Drug Therapy, Combination; Fema | 1988 |
[Stimulation of tumor growths by anesthesia].
Topics: Adrenalectomy; Anesthesia; Anesthetics; Animals; Carcinogens; Carcinoma, Ehrlich Tumor; Cell Differe | 1967 |
Inhibition of uridine incorporation into RNA in mammalian cells by agents affecting the properties of the cell membrane: chloropromazine, dipyridamole and phenylethanol.
Topics: Animals; Antifungal Agents; Benzene Derivatives; Carbon Radioisotopes; Carcinoma, Ehrlich Tumor; Cel | 1973 |