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chlorpromazine and Burns

chlorpromazine has been researched along with Burns in 24 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Burns: Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.

Research Excerpts

ExcerptRelevanceReference
"Chlorpromazine administered to Sprague-Dawley rats 30 minutes prior to burning dramatically minimized burn oedema by a factor of 7 compared with controls."7.66Acquired local resistance to burns: prevention of its acquisition by chlorpromazine. ( Babyatsky, M; Bibi, RR; Levenson, SM, 1983)
"Chlorpromazine administered to Sprague-Dawley rats 30 minutes prior to burning dramatically minimized burn oedema by a factor of 7 compared with controls."3.66Acquired local resistance to burns: prevention of its acquisition by chlorpromazine. ( Babyatsky, M; Bibi, RR; Levenson, SM, 1983)
" Significant inhibition of oedema formation caused by thermal injury was observed for calcium carbaspirin, phenylbutazone, hydrocortisone, cryogenine and indomethacin when given daily beginning 2 days prior to thermal exposure and afterwards."3.65Evaluation of cryogenine on rat paw thermal oedema and rat isolated uterus. ( Malone, MH; Trottier, RW, 1973)
"He developed oliguric acute renal failure soon after the burn injury, although adequate resuscitation therapy was given, and survived following frequent haemodialysis."1.27Survival from acute renal failure after severe burns. ( Momma, S; Nishida, S; Sawada, Y; Takamizawa, A, 1984)
"It has been suggested that acute respiratory distress syndrome (ARDS) is induced by a cybernetic imbalance of the central nervous system secondary to alarm reaction-provoked intravascular coagulation into cerebral microvessels."1.27Acute respiratory distress syndrome (ARDS): the prophylactic effect of neurodepressant agents. ( de Oliveira Antonio, MP; de Oliveira, GG; Shimano, LT, 1986)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199022 (91.67)18.7374
1990's0 (0.00)18.2507
2000's1 (4.17)29.6817
2010's1 (4.17)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shao, QB1
Zhang, X1
Chen, XL1
Liu, Y1
Zhang, Q1
Liao, ZJ1
STUTTGEN, G1
AMANTE, S1
MANCINI, M1
FROMMEL, E1
FESZT, G1
FESZT, T1
ALMASSI, S1
TRINER, L1
MRAZ, M2
HORN, L1
CONVERSE, JM1
HAYASHI, G1
ANDERSON, J1
LEE, HA1
STROUD, CE1
Sawada, Y1
Momma, S1
Takamizawa, A1
Nishida, S1
Bibi, RR1
Babyatsky, M1
Levenson, SM1
Clancy, KD1
Lorenz, K1
Dries, D1
Gamelli, RL1
Hahn, EL1
Beitner, R1
Chen-Zion, M1
Sofer-Bassukevitz, Y1
Oster, Y1
Ben-Porat, H1
Morgenstern, H1
Wood, M1
de Oliveira, GG1
Shimano, LT1
de Oliveira Antonio, MP1
Noe, JM1
Aber, RC1
Malone, MH1
Trottier, RW1
Geiger, JP1
Gielchinsky, I1
Laird, SM1
Sage, M1
Braasch, D2
Rogausch, H1
Ryan, GB1
Hurley, JV1
Zaets, TL1
Borisova, TA1

Reviews

1 review available for chlorpromazine and Burns

ArticleYear
Plasma drug binding: implications for anesthesiologists.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:7

    Topics: Age Factors; Alfentanil; Alprenolol; Anesthesia; Anesthetics; Blood Proteins; Bupivacaine; Burns; Ca

1986

Other Studies

23 other studies available for chlorpromazine and Burns

ArticleYear
[Protective effect of early application of lytic cocktail on small intestine of severely scalded rats].
    Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns, 2010, Volume: 26, Issue:3

    Topics: Animals; Burns; Chlorpromazine; Drug Combinations; Intestinal Mucosa; Intestine, Small; Male; Meperi

2010
[Therapeutic block of the autonomic nervous system in severe burns].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1955, Volume: 6, Issue:8

    Topics: Autonomic Nervous System; Burns; Chlorpromazine; Meperidine; Phenothiazines

1955
[Ganglion blockers, alarm reaction and experimental shock caused by burns].
    Minerva chirurgica, 1956, Apr-15, Volume: 11, Issue:7

    Topics: Burns; Chlorpromazine

1956
[Role of diencephalon and vagus centers during traumatic stress, burns, hypothermia and hyperthermia (morphine, chlorpromazine, ACTH and cholinergy)].
    La Presse medicale, 1957, Oct-05, Volume: 55, Issue:71

    Topics: Adrenocorticotropic Hormone; Body Temperature; Burns; Chlorpromazine; Diencephalon; Fever; Hypotherm

1957
[The effect of neuroplegic substances on the activity of alkaline phosphatase in the liver of rats in conditions of burn shock].
    Biulleten' eksperimental'noi biologii i meditsiny, 1960, Volume: 49

    Topics: Alkaline Phosphatase; Animals; Burns; Chlorpromazine; Liver; Meperidine; Phosphoric Monoester Hydrol

1960
Relation of the effect of chlorpromazine and pentamethonium to the time of administration in burn shock.
    Physiologia bohemoslovenica, 1962, Volume: 11

    Topics: Bis-Trimethylammonium Compounds; Burns; Chlorpromazine; Shock

1962
The influence of chlorpromazine and pentamethonium on the carbohydrate metabolism and the resistance to trauma and to burn shock in rats.
    Archives internationales de pharmacodynamie et de therapie, 1963, Feb-01, Volume: 141

    Topics: Animals; Bis-Trimethylammonium Compounds; Blood Glucose; Burns; Carbohydrate Metabolism; Chlorpromaz

1963
Chlorpromazine in protection from acute effects of extensive high temperature skin injury in rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1963, Volume: 113

    Topics: Animals; Burns; Chlorpromazine; Fever; Hot Temperature; Rats; Skin; Temperature

1963
[STUDIES ON ANALGESICS. 2. ON A METHOD FOR EVALUATING THE ANALGESIC POTENCY OF DRUGS USING HOT WATER STIMULATION].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1963, Jul-20, Volume: 59

    Topics: Acetanilides; Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Biological Assay; Bur

1963
HAEMODIALYSIS IN INFANTS AND SMALL CHILDREN.
    British medical journal, 1965, May-29, Volume: 1, Issue:5447

    Topics: Acute Kidney Injury; Barbiturates; Bronchopneumonia; Burns; Child; Chlorpromazine; Humans; Infant; K

1965
Survival from acute renal failure after severe burns.
    Burns, including thermal injury, 1984, Volume: 11, Issue:2

    Topics: Acute Kidney Injury; Adult; Burns; Chlorpromazine; Humans; Kidney; Male; Renal Dialysis; Resuscitati

1984
Acquired local resistance to burns: prevention of its acquisition by chlorpromazine.
    Burns, including thermal injury, 1983, Volume: 9, Issue:6

    Topics: Animals; Burns; Chlorpromazine; Edema; Hindlimb; Male; Rats; Rats, Inbred Strains

1983
Chlorpromazine modulates cytokine expression in the liver and lung after burn injury and endotoxemia.
    The Journal of trauma, 2000, Volume: 48, Issue:2

    Topics: Animals; Burns; Chemokine CCL4; Chlorpromazine; Endotoxemia; Escherichia coli Infections; Interleuki

2000
Therapeutic and prophylactic treatment of skin burns with several calmodulin antagonists.
    General pharmacology, 1989, Volume: 20, Issue:2

    Topics: Adenosine Triphosphate; Animals; Burns; Calmodulin; Chlorpromazine; Fluphenazine; Hemoglobins; Hexok

1989
Acute respiratory distress syndrome (ARDS): the prophylactic effect of neurodepressant agents.
    The Journal of trauma, 1986, Volume: 26, Issue:5

    Topics: Animals; Burns; Central Nervous System Depressants; Chlorpromazine; Diazepam; Dogs; Haloperidol; Hum

1986
Treatment of fever in burned children. A therapeutic program.
    Clinical pediatrics, 1973, Volume: 12, Issue:6

    Topics: Acetaminophen; Adrenergic alpha-Antagonists; Burns; Child; Child, Preschool; Chlorpromazine; Fever;

1973
Evaluation of cryogenine on rat paw thermal oedema and rat isolated uterus.
    British journal of pharmacology, 1973, Volume: 48, Issue:2

    Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Benzocaine; Bradykinin; Burns; Chlorpromazine; Dose-Re

1973
Acute pulmonary insufficiency. Treatment in Vietnam casualties.
    Archives of surgery (Chicago, Ill. : 1960), 1971, Volume: 102, Issue:4

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Blast Injuries; Burns; Child; Chlorpromazine; Diuretics; E

1971
Psychosis and ketamine.
    British medical journal, 1972, Jan-22, Volume: 1, Issue:5794

    Topics: Adult; Anesthetics; Bipolar Disorder; Burns; Chlorpromazine; Cyclohexanes; Female; Humans; Ketamine;

1972
Decreased red-cell deformability after severe burns, determined with the chlorpromazine test.
    Pflugers Archiv : European journal of physiology, 1971, Volume: 323, Issue:1

    Topics: Animals; Burns; Cell Membrane; Centrifugation; Chlorpromazine

1971
The drug inhibition of increased vascular permeability.
    The Journal of pathology and bacteriology, 1968, Volume: 96, Issue:2

    Topics: Animals; Blood Vessels; Burns; Capillary Permeability; Chlorpromazine; Digoxin; Diphenhydramine; Ind

1968
[Changes in protein metabolism in experimental burns against the background of aminizin action].
    Biulleten' eksperimental'noi biologii i meditsiny, 1965, Volume: 60, Issue:12

    Topics: Animals; Burns; Chlorpromazine; Proteins; Rabbits

1965
[Stabilization of the biconcave form of erythrocytes by chloropromazine following severe burns].
    Die Naturwissenschaften, 1966, Volume: 53, Issue:6

    Topics: Animals; Burns; Chlorpromazine; Dogs; Erythrocytes; Rabbits; Shock, Traumatic

1966