chlorpromazine has been researched along with Bright Disease in 9 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Bright Disease: A historical classification which is no longer used. It described acute glomerulonephritis, acute nephritic syndrome, or acute nephritis. Named for Richard Bright.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chlorpromazine blocks antibody-mediated redistribution of cell surface antigens in vitro and in vivo and inhibits the development of passive Heymann glomerulonephritis, a disease characterized by in situ formation of immune complexes (Camussi et al J Immunol 1986, 136:2127-2135)." | 7.67 | Effect of chlorpromazine on the development of experimental glomerulonephritis and Arthus reaction. ( Andres, G; Brentjens, J; Camussi, G; Niesen, N; Salvidio, G, 1988) |
| "The effect of chlorpromazine, one of several calmodulin antagonists that inhibit cytoskeletal movement, on the local kinetics of injected proteinuria-inducing MoAb 5-1-6 was examined to test the hypothesis that proteinuria is inhibited if the antigen recognized by MoAb 5-1-6 or injected MoAb remains on the surface of epithelial foot processes." | 3.68 | Effect of chlorpromazine on kinetics of injected monoclonal antibody in MoAb-induced glomerular injury. ( Arakawa, M; Kawachi, H; Nishi, S; Oite, T; Shimizu, F; Takashima, N, 1993) |
| "Chlorpromazine blocks antibody-mediated redistribution of cell surface antigens in vitro and in vivo and inhibits the development of passive Heymann glomerulonephritis, a disease characterized by in situ formation of immune complexes (Camussi et al J Immunol 1986, 136:2127-2135)." | 3.67 | Effect of chlorpromazine on the development of experimental glomerulonephritis and Arthus reaction. ( Andres, G; Brentjens, J; Camussi, G; Niesen, N; Salvidio, G, 1988) |
| "Chlorpromazine treatment prevented both the cell proliferation and the brush border loss produced by divalent antibodies, although clumping of microvilli was not prevented." | 1.27 | Antibody-mediated proliferation of proximal tubule cells requires cross-linking of antigenic determinants. ( Brodkin, M; Noble, B, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (88.89) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| HIRSCH, S | 1 |
| VISENTIN, G | 1 |
| MALOSSI, M | 2 |
| Takashima, N | 1 |
| Kawachi, H | 1 |
| Oite, T | 1 |
| Nishi, S | 1 |
| Arakawa, M | 1 |
| Shimizu, F | 1 |
| Brodkin, M | 1 |
| Noble, B | 2 |
| Camussi, G | 2 |
| Salvidio, G | 1 |
| Niesen, N | 1 |
| Brentjens, J | 1 |
| Andres, G | 2 |
| Van Liew, J | 1 |
| Brentjens, JR | 1 |
| Marchesoni, C | 1 |
| Melchiori, G | 1 |
| Fruet, G | 1 |
| Malossi, R | 1 |
| Giacomoni, C | 1 |
| Enger, E | 1 |
9 other studies available for chlorpromazine and Bright Disease
| Article | Year |
|---|---|
[Pulmonary edema during the course of acute glomerulonephritis treated with chlorpromazine].
Topics: Acute Disease; Chlorpromazine; Edema; Glomerulonephritis; Humans; Pulmonary Edema | 1960 |
[Results obtained by means of the treatment of acute diffuse glomerulonephritis in the oliguric phase with chlopromazine].
Topics: Acute Disease; Chlorpromazine; Glomerulonephritis; Humans | 1961 |
[Usefulness of chlorpromazine treatment in acute diffuse glomerulonephritis in infancy in reference to the permeability of the blood vessels].
Topics: Acute Disease; Capillary Permeability; Chlorpromazine; Glomerulonephritis; Humans; Permeability | 1962 |
Effect of chlorpromazine on kinetics of injected monoclonal antibody in MoAb-induced glomerular injury.
Topics: Animals; Antibodies, Monoclonal; Chlorpromazine; Female; Fluorescent Antibody Technique; Glomerulone | 1993 |
Antibody-mediated proliferation of proximal tubule cells requires cross-linking of antigenic determinants.
Topics: Animals; Chlorpromazine; Epitopes; Female; Fluorescent Antibody Technique; Glomerulonephritis; Immun | 1988 |
Effect of chlorpromazine on the development of experimental glomerulonephritis and Arthus reaction.
Topics: Animals; Antigens; Arthus Reaction; Chlorpromazine; Fluorescent Antibody Technique; Glomerulonephrit | 1988 |
Pathogenesis of passive Heymann glomerulonephritis: chlorpromazine inhibits antibody-mediated redistribution of cell surface antigens and prevents development of the disease.
Topics: Animals; Antigen-Antibody Complex; Antigens, Surface; Cells, Cultured; Chlorpromazine; Complement Ac | 1986 |
[Acute post-infectious glomerulonephritis. Pathogenetic considerations and clinical results of using chlorpromazine].
Topics: Acute Disease; Adolescent; Child; Child, Preschool; Chlorpromazine; Drug Evaluation; Glomerulonephri | 1986 |
[Therapy of hypertensive crises].
Topics: Antihypertensive Agents; Chlorpromazine; Glomerulonephritis; Humans; Hypertension, Renal; Intensive | 1968 |