chlorpromazine has been researched along with Brain Injuries in 42 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A patient with neurogenic pulmonary edema was successfully treated with the alpha-blocking agent, chlorpromazine." | 7.67 | Chlorpromazine treatment for neurogenic pulmonary edema. ( Howe, JF; Pierce, KR; Tamas, L; Wohns, RN, 1985) |
| "A patient with neurogenic pulmonary edema was successfully treated with the alpha-blocking agent, chlorpromazine." | 3.67 | Chlorpromazine treatment for neurogenic pulmonary edema. ( Howe, JF; Pierce, KR; Tamas, L; Wohns, RN, 1985) |
| "The effects of aminazin and aspirin on brain injuries in animals with immunological hypersensitivity of the body were studied." | 3.66 | [Nerve tissue ultrastructure in experimental brain injuries in animals with increased immunobiologic reactivity following treatment with certain desensitizing drugs]. ( Sukhorukova, LI, 1981) |
| "Intravenous migraine therapy reduces PTH pain scores for children presenting within 14 days after mTBI." | 1.42 | Intravenous migraine therapy in children with posttraumatic headache in the ED. ( Byczkowski, T; Chan, S; Kurowski, B; Timm, N, 2015) |
| "Fever or pyrexia is a common clinical phenomenon." | 1.28 | Fever after traumatic brain injury. ( Segatore, M, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 37 (88.10) | 18.7374 |
| 1990's | 2 (4.76) | 18.2507 |
| 2000's | 2 (4.76) | 29.6817 |
| 2010's | 1 (2.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chan, S | 1 |
| Kurowski, B | 1 |
| Byczkowski, T | 1 |
| Timm, N | 1 |
| POCIDALO, JJ | 1 |
| TARDIEU, C | 1 |
| DE LANGE, J | 1 |
| PRIMAC, DW | 2 |
| MIRSKY, AF | 2 |
| ROSVOLD, HE | 2 |
| LECHTENBERG, HW | 1 |
| UGLOV, FG | 2 |
| LUCHKO, GD | 2 |
| OTA, S | 1 |
| FARETRA, G | 1 |
| GOZUN, C | 1 |
| ANSTOCK, F | 1 |
| MEYER, HH | 1 |
| HALSWICK, R | 1 |
| IVANOV, FI | 1 |
| PAUTLER, EL | 1 |
| CLARK, G | 1 |
| Koponen, H | 1 |
| Larmo, I | 1 |
| Baguley, IJ | 1 |
| Cameron, ID | 1 |
| Green, AM | 1 |
| Slewa-Younan, S | 1 |
| Marosszeky, JE | 1 |
| Gurka, JA | 1 |
| Rogacheva, SK | 1 |
| Burakova, NS | 1 |
| Rosengren, LE | 2 |
| Persson, LI | 2 |
| Hoppe, E | 1 |
| Christensen, L | 1 |
| Christensen, KN | 1 |
| Sukhorukova, LI | 1 |
| Chengappa, KN | 1 |
| Nimgaonkar, VL | 1 |
| Bachert, C | 1 |
| Yang, ZW | 1 |
| Rabin, BS | 1 |
| Ganguli, R | 1 |
| Cold, GE | 1 |
| Lipper, S | 1 |
| Tuchman, MM | 1 |
| Borshchagovskiĭ, ML | 2 |
| Dubikaitis, IuV | 2 |
| Segatore, M | 1 |
| Orlovskaia, DD | 1 |
| Kleshchinov, VN | 1 |
| Wohns, RN | 1 |
| Tamas, L | 1 |
| Pierce, KR | 1 |
| Howe, JF | 1 |
| Buxton Hopkin, DA | 1 |
| Marsden, CA | 1 |
| Guldberg, HC | 1 |
| Petersen, EA | 1 |
| Haase, J | 1 |
| Dubinsky, B | 1 |
| Robichaud, RC | 1 |
| Goldberg, ME | 1 |
| Sherman, DM | 1 |
| Usanov, EI | 1 |
| Nybäck, H | 1 |
| Buletsa, BA | 1 |
| Smirnov, AD | 1 |
| Lapides, MI | 1 |
| Mamtseva, VN | 1 |
| Lopatin, AS | 1 |
| Deshchekina, MF | 1 |
| Fadeeva, MA | 1 |
| Beattie, CW | 1 |
| Chernov, HI | 1 |
| Bernard, PS | 1 |
| Glenny, FH | 1 |
| Grubnik, VM | 1 |
| Nerobeev, VD | 1 |
1 trial available for chlorpromazine and Brain Injuries
| Article | Year |
|---|---|
Treatment of chronic post-traumatic organic brain syndrome with dextroamphetamine: first reported case.
Topics: Accidents, Traffic; Adult; Amitriptyline; Brain Injuries; Chlorpromazine; Dextroamphetamine; Drug Th | 1976 |
41 other studies available for chlorpromazine and Brain Injuries
| Article | Year |
|---|---|
Intravenous migraine therapy in children with posttraumatic headache in the ED.
Topics: Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Brain Injuries; | 2015 |
[Prevention by chlorpromazine (R.P. 4560) of serious vascular accidents after experimental lesions on the cerebral peduncles].
Topics: Accidents; Brain Injuries; Cerebral Peduncle; Chlorpromazine; Humans | 1954 |
Notes on a more active treatment of concussion of the brain.
Topics: Brain; Brain Concussion; Brain Injuries; Chlorpromazine; Humans; Manipulation, Osteopathic | 1954 |
Effects of centrally acting drugs on two tests of brain damage.
Topics: Barbiturates; Brain; Brain Injuries; Central Nervous System Agents; Chlorpromazine; Humans; Lysergic | 1957 |
Effects of centrally acting drugs on two tests of brain damage.
Topics: Barbiturates; Brain; Brain Injuries; Central Nervous System Agents; Chlorpromazine; Humans; Lysergic | 1957 |
Effects of centrally acting drugs on two tests of brain damage.
Topics: Barbiturates; Brain; Brain Injuries; Central Nervous System Agents; Chlorpromazine; Humans; Lysergic | 1957 |
Effects of centrally acting drugs on two tests of brain damage.
Topics: Barbiturates; Brain; Brain Injuries; Central Nervous System Agents; Chlorpromazine; Humans; Lysergic | 1957 |
[Closed craniocerebral injuries and their therapy].
Topics: Brain Injuries; Chlorpromazine; Craniocerebral Trauma; Edema; Humans; Skull Fractures; Sorbitol | 1963 |
[Use of neuroplegic and ganglion-blocking drugs in the treatment of craniocerebral injuries].
Topics: Bis-Trimethylammonium Compounds; Brain Injuries; Chlorpromazine; Craniocerebral Trauma; Diphenhydram | 1962 |
[CLINICAL ASPECTS OF THE SEQUELAE TO HEAD INJURIES].
Topics: Brain Injuries; Cerebral Hemorrhage; Child; Chlordiazepoxide; Chlorpromazine; Craniocerebral Trauma; | 1963 |
THE USE OF DRUG COMBINATIONS IN PEDIATRIC PSYCHIATRY.
Topics: Adolescent; Biomedical Research; Brain; Brain Damage, Chronic; Brain Injuries; Child; Child Behavior | 1964 |
[ON THE TREATMENT OF ERETHISM IN CHILDREN WITH BRAIN DAMAGE].
Topics: Brain; Brain Damage, Chronic; Brain Injuries; Child; Child Behavior Disorders; Chlorpromazine; Drug | 1964 |
[Clinical aspects and therapy of acute psottraumatic psychoses].
Topics: Brain; Brain Injuries; Chlorpromazine; Humans; Mental Disorders; Psychotic Disorders | 1954 |
[On the influence of megaphen, nembutal and novocain on spontaneous EEG and bioelectrical response to light stimuli in brain-injured rabbits].
Topics: Animals; Brain; Brain Injuries; Chlorpromazine; Electroencephalography; Electrophysiological Phenome | 1960 |
[Treatment with small doses of aminazin of remote sequelae of cerebro-cranial injuries].
Topics: Brain; Brain Injuries; Chlorpromazine; Humans | 1960 |
The effect of chlorpromazine on the discrimination between intermittent photic stimulation and a steady light in normal and brain-damaged cats.
Topics: Animals; Brain; Brain Diseases; Brain Injuries; Cats; Chlorpromazine; Learning; Light; Photic Stimul | 1961 |
Reversal of antipsychotic-induced weight gain during quetiapine treatment.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Brain Injuries; Chlorpromazine; Dibenzothiazepines; Hu | 2003 |
Pharmacological management of Dysautonomia following traumatic brain injury.
Topics: Adult; Autonomic Nervous System Diseases; Brain Injuries; Case-Control Studies; Chlorpromazine; Fema | 2004 |
[Mechanisms of spreading generalized activation of the cerebral cortex due to a mechanical injury of the latter].
Topics: Animals; Brain; Brain Injuries; Cerebral Cortex; Chlorpromazine; Electroencephalography; Rabbits; Re | 1966 |
[A case of hyperkinesia caused by unilateral lesion of the medial part of the thalamus in a dog].
Topics: Animals; Brain Injuries; Chlorpromazine; Dogs; Head; Humans; Hyperkinesis; Movement Disorders; Paras | 1966 |
Effect of ethanol, chlorpromazine and dexamethasone on blood-brain barrier dysfunction to albumin around large cerebral stab wounds.
Topics: Alcoholic Intoxication; Animals; Blood-Brain Barrier; Brain Injuries; Chlorpromazine; Dexamethasone; | 1981 |
The clinical outcome of patients with severe head injuries, treated with highdose dexamethasone, hyperventilation and barbiturates.
Topics: Adolescent; Adult; Age Factors; Aged; Brain Injuries; Child; Child, Preschool; Chlorpromazine; Dexam | 1981 |
[Nerve tissue ultrastructure in experimental brain injuries in animals with increased immunobiologic reactivity following treatment with certain desensitizing drugs].
Topics: Animals; Aspirin; Autoimmune Diseases; Brain; Brain Edema; Brain Injuries; Chinchilla; Chlorpromazin | 1981 |
Obstetric complications and autoantibodies in schizophrenia.
Topics: Adult; Antipsychotic Agents; Autoantibodies; Brain Injuries; Chlorpromazine; Enzyme-Linked Immunosor | 1995 |
Cerebral metabolic rate of oxygen (CMRO2) in the acute phase of brain injury.
Topics: Adolescent; Adult; Aged; Blood Pressure; Brain; Brain Injuries; Cerebrovascular Circulation; Child; | 1978 |
Chlorpromazine treatment of blood-brain barrier dysfunction. A quantitative and fluorescence microscopical study on small cerebral stab wounds in the rat.
Topics: Albumins; Animals; Blood-Brain Barrier; Brain Injuries; Cerebral Cortex; Chlorpromazine; Ethanol; Fr | 1979 |
[Clinico-electroencephalographic characteristics of the condition of brain stem systems following surgical and non-surgical brain injury].
Topics: Adult; Amphetamine; Anesthesia, General; Autonomic Nervous System; Brain Injuries; Brain Neoplasms; | 1976 |
Fever after traumatic brain injury.
Topics: Adult; Body Temperature Regulation; Brain Injuries; Chlorpromazine; Cryotherapy; Decision Making; Fe | 1992 |
[Neurons in the hyperchromic state].
Topics: Animals; Autolysis; Brain Injuries; Cell Nucleus; Cerebral Cortex; Chlorpromazine; Chromatin; Male; | 1986 |
Chlorpromazine treatment for neurogenic pulmonary edema.
Topics: Adrenergic alpha-Antagonists; Adult; Brain Diseases; Brain Injuries; Chlorpromazine; Humans; Male; O | 1985 |
Severe head injuries.
Topics: Brain Injuries; Chlorpromazine; Shock, Traumatic | 1968 |
The role of monoamines in rotation induced or potentiated by amphetamine after nigral, raphe and mesencephalic reticular lesions in the rat brain.
Topics: Amines; Amphetamine; Animals; Behavior, Animal; Brain; Brain Injuries; Catalepsy; Cerebral Cortex; C | 1973 |
Unstable fractures in children with acute, severe brain injury.
Topics: Accidents, Traffic; Arm Injuries; Brain Injuries; Chlorpromazine; Female; Femoral Fractures; Fractur | 1974 |
Effects of (-) 9 -trans-tetrahydrocannabinol and its selectivity in several models of aggressive behavior.
Topics: Aggression; Animals; Behavior, Animal; Brain Injuries; Cannabis; Cats; Chlorpromazine; Dronabinol; E | 1973 |
[Effectiveness of certain therapeutic measures in the acute period of isolated craniocerebral injuries].
Topics: Animals; Autonomic Nerve Block; Body Temperature; Brain; Brain Concussion; Brain Edema; Brain Injuri | 1973 |
Effect of brain lesions and chlorpromazine on accumulation and disappearance of catecholamines formed in vivo from 14 C-tyrosine.
Topics: Animals; Basal Ganglia; Brain Injuries; Carbon Isotopes; Chlorpromazine; Corpus Striatum; Dopamine; | 1972 |
[The diagnostic importance of functional tests of facial skin in closed craniocerebral trauma patients].
Topics: Body Temperature; Brain Injuries; Chloroform; Chlorpromazine; Electric Stimulation; Epinephrine; Eth | 1969 |
[Treatment of psychomotor excitations in patients with acute cerebrocranial injuries].
Topics: Brain Injuries; Cerebrospinal Fluid; Chlorpromazine; Female; Humans; Male; Pressure; Psychomotor Dis | 1969 |
[On the treatment of psycopath-like states in children with psychotropic drugs after infectious and traumatic disorders of the central nervous system].
Topics: Adolescent; Antidepressive Agents; Antisocial Personality Disorder; Brain Diseases; Brain Injuries; | 1967 |
[Treatment of status epilepticus with the intravenous administration of aminazine].
Topics: Adult; Brain Injuries; Chlorpromazine; Epilepsy; Female; Humans; Injections, Intravenous; Male | 1968 |
[Aminazin in the complex treatment of sick newborns].
Topics: Birth Injuries; Brain Injuries; Central Nervous System Diseases; Chlorpromazine; Humans; Infant; Inf | 1969 |
[Basic clinical syndromes of vital disorders in severe lesions of the skull and brain].
Topics: Aminophylline; Bis-Trimethylammonium Compounds; Brain Injuries; Chlorpromazine; Electroencephalograp | 1969 |
Pharmacological alteration of hyper-reactivity in rats with septal and hypothalamic lesions.
Topics: Aminopyrine; Analgesics; Animals; Behavior, Animal; Brain; Brain Injuries; Cerebral Ventricles; Chlo | 1969 |
[Experience in the treatment of psychomotor excitation with acute cerebrocranial trauma in a rural district hospital].
Topics: Adult; Brain Injuries; Chlorpromazine; Humans; Male; Reflex, Abnormal; Shock, Traumatic | 1965 |