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chlorpromazine and Brain Edema

chlorpromazine has been researched along with Brain Edema in 8 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)

Research Excerpts

ExcerptRelevanceReference
"The effects of antihypertensive drugs, such as nifedipine, chlorpromazine, reserpine and thiopental on mean arterial blood pressure (ABP), mean intracranial pressure (ICP) and cerebral perfusion pressure (CPP) were studied in 43 patients with systemic hypertension and intracranial hypertension due to hemorrhagic cerebrovascular diseases and other causes."3.68Effects of antihypertensive drugs on intracranial hypertension. ( Handa, Y; Hayashi, M; Hirose, S; Kawano, H; Kobayashi, H; Nozaki, J, 1991)
"The effects of aminazin and aspirin on brain injuries in animals with immunological hypersensitivity of the body were studied."3.66[Nerve tissue ultrastructure in experimental brain injuries in animals with increased immunobiologic reactivity following treatment with certain desensitizing drugs]. ( Sukhorukova, LI, 1981)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19906 (75.00)18.7374
1990's1 (12.50)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Matsusue, A1
Hara, K1
Kageura, M1
Kashiwagi, M1
Lu, W1
Ishigami, A1
Gotohda, T1
Tokunaga, I1
Nisimura, A1
Sugimura, T1
Kubo, S1
BULLE, PH1
FANTIS, A1
KRYSPIN, J1
Sukhorukova, LI1
Hirose, S1
Handa, Y1
Kobayashi, H1
Kawano, H1
Nozaki, J1
Hayashi, M2
Sherman, DM1
Usanov, EI1
Yamamoto, S1
Yamamoto, T1
Polácek, L1
Krejcí, D1

Other Studies

8 other studies available for chlorpromazine and Brain Edema

ArticleYear
Genetic analysis of ryanodine receptor 1 gene and carnitine palmitoyltransferase II gene: an autopsy case of neuroleptic malignant syndrome related to vegetamin.
    Legal medicine (Tokyo, Japan), 2009, Volume: 11 Suppl 1

    Topics: Adult; Amino Acid Substitution; Antipsychotic Agents; Brain; Brain Edema; Carnitine O-Palmitoyltrans

2009
Effects of reserpine and chlorpromazine in prevention of cerebral edema and reversible cell damage.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1957, Volume: 94, Issue:3

    Topics: Biomedical Research; Brain Edema; Chlorpromazine; Edema; Reserpine

1957
[Experimental pharmacological influencing of brain edema].
    Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti, 1957, Volume: 36, Issue:11

    Topics: Brain; Brain Diseases; Brain Edema; Chlorpromazine; Edema

1957
[Nerve tissue ultrastructure in experimental brain injuries in animals with increased immunobiologic reactivity following treatment with certain desensitizing drugs].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1981, Volume: 81, Issue:5

    Topics: Animals; Aspirin; Autoimmune Diseases; Brain; Brain Edema; Brain Injuries; Chinchilla; Chlorpromazin

1981
Effects of antihypertensive drugs on intracranial hypertension.
    Zentralblatt fur Neurochirurgie, 1991, Volume: 52, Issue:2

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Brain Edema; Cerebral Hemorrhage; Cerebrospina

1991
[Effectiveness of certain therapeutic measures in the acute period of isolated craniocerebral injuries].
    Voenno-meditsinskii zhurnal, 1973, Volume: 10

    Topics: Animals; Autonomic Nerve Block; Body Temperature; Brain; Brain Concussion; Brain Edema; Brain Injuri

1973
[Acute intracranial hypertension].
    No to shinkei = Brain and nerve, 1971, Volume: 23, Issue:3

    Topics: Adult; Aged; Betamethasone; Blood Pressure; Brain Edema; Cerebrospinal Fluid; Chlorpromazine; Electr

1971
[Chronic brucellosis with the features of meningoencephalopolyradiculoneuritis with transient edema of the brain stem].
    Ceskoslovenska neurologie, 1968, Volume: 31, Issue:4

    Topics: Adult; Anti-Bacterial Agents; Brain Edema; Brucella Vaccine; Brucellosis; Chlorpromazine; Chronic Di

1968