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chlorpromazine and Bradycardia

chlorpromazine has been researched along with Bradycardia in 14 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Bradycardia: Cardiac arrhythmias that are characterized by excessively slow HEART RATE, usually below 50 beats per minute in human adults. They can be classified broadly into SINOATRIAL NODE dysfunction and ATRIOVENTRICULAR BLOCK.

Research Excerpts

ExcerptRelevanceReference
"A two-month-old white girl presented to our facility with increasing lethargy and new onset apnea and bradycardia following a week of upper respiratory tract infection symptoms."8.78Phenothiazine-associated apnea in two siblings. ( Blumer, JL; Buck, ML, 1991)
"A two-month-old white girl presented to our facility with increasing lethargy and new onset apnea and bradycardia following a week of upper respiratory tract infection symptoms."4.78Phenothiazine-associated apnea in two siblings. ( Blumer, JL; Buck, ML, 1991)
" Activities of the compounds in antagonizing reserpine-induced ptosis in rabbits and prolongation of alcohol hypnosis in mice give good correlation with their clinical actions, whilst their activities in augmenting excitation of rats by amphetamine and yohimbine toxicity in mice, and in reversing reserpine-induced bradycardia in rats offer further evidence for drug-induced sensitization to adrenergic or tryptaminic mechanisms, which is not however specific for antidepressant agents."3.64A COMPARISON OF IMIPRAMINE, CHLORPROMAZINE AND RELATED DRUGS IN VARIOUS TESTS INVOLVING AUTONOMIC FUNCTIONS AND ANTAGONISM OF RESERPINE. ( HALLIWELL, G; QUINTON, RM; WILLIAMS, FE, 1964)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199013 (92.86)18.7374
1990's1 (7.14)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
KAROLY, AJ1
DOMINO, EF1
WALKER, EL1
FELLER, K1
STAIB, AH2
HALLIWELL, G1
QUINTON, RM1
WILLIAMS, FE1
Buck, ML1
Blumer, JL1
Majumdar, DK1
Zipf, HF1
Hamacher, J1
Lehr, E2
Werner, G2
Méhes, J1
Decsi, L1
Várszegi, MK1
Hideg, H1
Hankovszky, OH1
Kobinger, W1
Walland, A1
Thalme, B1
Belfrage, P1
Raabe, N1
Stein, H1
Rubin, S1
Merin, G1
Cotev, S1
Borman, JB1
Jaju, BP1
Srimal, RC1
Dhawan, KN1
Gupta, GP1
Thuránszky, K1

Reviews

1 review available for chlorpromazine and Bradycardia

ArticleYear
Phenothiazine-associated apnea in two siblings.
    DICP : the annals of pharmacotherapy, 1991, Volume: 25, Issue:3

    Topics: Apnea; Bradycardia; Chlorpromazine; Drug Therapy, Combination; Family; Female; Humans; Infant; Male;

1991

Other Studies

13 other studies available for chlorpromazine and Bradycardia

ArticleYear
DIFFERENTIAL EFFECTS OF VARIOUS DRUGS ON THE CONDITIONED MOTOR AND HEART RATE RESPONSES IN DOGS RESISTANT TO EXTINCTION.
    Archives internationales de pharmacodynamie et de therapie, 1964, Mar-01, Volume: 148

    Topics: Bradycardia; Chlorpromazine; Conditioning, Classical; Decamethonium Compounds; Dogs; Heart; Heart Ra

1964
[INVESTIGATIONS CONCERNING THE BRADYCARDIA INDUCED BY CHLORPROMAZINE].
    Archives internationales de pharmacodynamie et de therapie, 1964, Mar-01, Volume: 148

    Topics: Acetates; Adrenalectomy; Animals; Atropine; Bis-Trimethylammonium Compounds; Bradycardia; Carotid Si

1964
A COMPARISON OF IMIPRAMINE, CHLORPROMAZINE AND RELATED DRUGS IN VARIOUS TESTS INVOLVING AUTONOMIC FUNCTIONS AND ANTAGONISM OF RESERPINE.
    British journal of pharmacology and chemotherapy, 1964, Volume: 23

    Topics: Alcoholic Intoxication; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Autonomic Nervou

1964
[EKG changes in the rat following chlorpromazine in the course of postnatal development].
    Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 166, Issue:1

    Topics: Animals; Animals, Newborn; Bradycardia; Central Nervous System; Chlorpromazine; Electrocardiography;

1967
[Comparative studies on the effect of Veratrum alkaloids on cardiac contraction kinetics].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1967, Volume: 257, Issue:1

    Topics: Acetylcholine; Biomechanical Phenomena; Bradycardia; Chloroform; Chlorpromazine; Depression, Chemica

1967
[Influencing of heart rhythm by injection of mescaline into the lateral cerebral ventricle of some mammals].
    Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1970, Volume: 266, Issue:4

    Topics: Animals; Arrhythmia, Sinus; Autonomic Nervous System; Bradycardia; Cerebral Ventricles; Chlorpromazi

1970
Inhibitory effect of 1-alkylbenzimidazoles on gastric secretion in the rat.
    The Journal of pharmacy and pharmacology, 1966, Volume: 18, Issue:8

    Topics: Acetylcholine; Animals; Behavior, Animal; Blood Pressure; Bradycardia; Carbachol; Cats; Central Nerv

1966
Facilitation of vagal reflex bradycardia by an action of clonidine on central -receptors.
    European journal of pharmacology, 1972, Volume: 19, Issue:2

    Topics: Acetylcholine; Adrenergic beta-Antagonists; Animals; Blood Pressure; Bradycardia; Cerebellum; Chlorp

1972
Lumbar epidural analgesia in labour. I. Acid-base balance and clinical condition of mother, fetus and newborn child.
    Acta obstetricia et gynecologica Scandinavica, 1974, Volume: 53, Issue:1

    Topics: Acidosis; Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Blood; Body Temperature; Bradycardia

1974
Successful prolonged resuscitation after open heart surgery.
    Thorax, 1971, Volume: 26, Issue:4

    Topics: Adult; Arrhythmias, Cardiac; Atrial Fibrillation; Blood Gas Analysis; Blood Pressure; Bradycardia; B

1971
Effect of lysergic acid diethylamide (LSD-25) on morphine induced bradycardia.
    Japanese journal of pharmacology, 1967, Volume: 17, Issue:4

    Topics: Animals; Bradycardia; Chlorpromazine; Electrocardiography; Female; Heart Rate; Lysergic Acid Diethyl

1967
[Mescaline induced bradycardia and its antagonistic modification by chlorpromazine, pentobarbital and scopolamine after injection into lateral cerebral ventricle of mouse].
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:7

    Topics: Animals; Arrhythmias, Cardiac; Bradycardia; Cerebral Ventricles; Chlorpromazine; Depression, Chemica

1970
The role of the central nervous system on the action of epinephrine and adrenolytic drugs.
    Archives internationales de pharmacodynamie et de therapie, 1966, Volume: 159, Issue:1

    Topics: Animals; Blood Pressure; Bradycardia; Cats; Central Nervous System; Chlorpromazine; Decerebrate Stat

1966