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chlorpromazine and Bleeding

chlorpromazine has been researched along with Bleeding in 38 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Research Excerpts

ExcerptRelevanceReference
"In mongrel dogs with induced pancreatitis we studied the effects of the nonspecific phospholipase A2-inhibitors chlorpromazine, gabexate mesilate and CaNa2EDTA on the course of pancreatogenic shock and the intrapancreatic lysolecithin production."3.67[Phospholipase A2 inhibitors in hemorrhagic-necrotizing pancreatitis. Animal experiment evaluation of a new treatment concept]. ( Alles, JU; Kahle, M; Klein, U; König, W; Martin, U, 1985)
"Persistent hiccups have been reported to occur occasionally during rehabilitation hospitalizations."2.44Persistent hiccups during rehabilitation hospitalization: three case reports and review of the literature. ( Browne, BA; Schuchmann, JA, 2007)
"Chlorpromazine is a commonly used drug in several medical conditions associated with a wide range of side effects."1.72Life-threatening chlorpromazine-induced acquired haemophilia A in a patient with a cavernous malformation involving the medulla oblongata. ( Ackermann, F; David, A; Gratieux, J; Groh, M; Horodyckid, C; Marroun, I; Paule, R; Roumier, M; Stammler, R; Vasse, M; Verrat, A, 2022)
" Pretreatment with CPZ partially protected these organs from the toxic effects of CdCl(2)."1.30The antagonistic effect of chlorpromazine on cadmium toxicity. ( El-Ashmawy, IM; Youssef, SA, 1999)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199034 (89.47)18.7374
1990's1 (2.63)18.2507
2000's1 (2.63)29.6817
2010's0 (0.00)24.3611
2020's2 (5.26)2.80

Authors

AuthorsStudies
Stammler, R1
Ackermann, F1
Vasse, M1
Verrat, A1
David, A1
Horodyckid, C1
Gratieux, J1
Marroun, I1
Groh, M1
Roumier, M1
Paule, R1
Dorgalaleh, A1
Dabbagh, A1
Tabibian, S1
Bahraini, M1
Rafieemehr, H1
KELAN, M1
ZWEIFACH, BW2
BURGKHARDT, H1
HERSHEY, SG1
GUCCIONE, I1
FERTITTA, S1
SCIO, E1
CARRUTHERS, GF1
GOWDEY, CW1
SPURR, GB2
FARRAND, EA1
HORVATH, SM2
BLATTEIS, C1
SAVLOV, ED1
REGELSON, W1
MARCHAND, L1
BOREL, J1
FRECOURT, J1
COIFFU, B1
MESSER, M1
ZELENY, A1
LINDAUR, V1
KOZAK, J1
COSTA, E1
RINALDI, F1
FLOCH, M1
LEIBOWITZ, S1
KARACADAG, S1
KLOTZ, AP1
MILLAR, RA1
BENFEY, BG1
Schuchmann, JA1
Browne, BA1
Murphy, GP2
Schirmer, HK1
Mirand, EA1
Benson, DW2
Scott, WW1
Kassem, A1
Aguam, S1
Dow, RW1
Fry, WJ1
El-Ashmawy, IM1
Youssef, SA1
Girdwood, RH1
Powers, JC1
Shaftan, GW1
Herbsman, H1
Vargas, GC1
Pildes, RS1
Vidyasagar, D1
Keith, LG1
Niewenhuis, RJ1
Prozialeck, WC1
Kahle, M1
Klein, U1
König, W1
Martin, U1
Alles, JU1
Wiley, MK1
Pearlmutter, AF1
Miller, RE1
Niklasson, PM1
Blombäck, M1
Lundbergh, P1
Strandell, T1
Gazzaniga, AB1
Byrd, CL1
Stewart, DR1
Gross, RE1
Hansen, OH1
Henriksen, PB1
Török, B1
Tóth, I1
Largiadère, F1
Beard, J1
Meyer, V2
Knobil, E2
Lucas, ON1
Millar, GJ1
Jaques, LB1
Dyball, RE1
Schirmer, KA1

Reviews

2 reviews available for chlorpromazine and Bleeding

ArticleYear
Persistent hiccups during rehabilitation hospitalization: three case reports and review of the literature.
    American journal of physical medicine & rehabilitation, 2007, Volume: 86, Issue:12

    Topics: Aged; Amines; Anti-Anxiety Agents; Anticonvulsants; Cerebral Infarction; Chlorpromazine; Chronic Dis

2007
Venous pressure and other thoughts.
    Proceedings of the Royal Society of Medicine, 1969, Jul-07, Volume: 62, Issue:7

    Topics: Anesthesia; Blood Pressure; Blood Volume Determination; Cardiac Output; Catecholamines; Chlorpromazi

1969

Other Studies

36 other studies available for chlorpromazine and Bleeding

ArticleYear
Life-threatening chlorpromazine-induced acquired haemophilia A in a patient with a cavernous malformation involving the medulla oblongata.
    La Revue de medecine interne, 2022, Volume: 43, Issue:12

    Topics: Adult; Chlorpromazine; Hemophilia A; Hemorrhage; Humans; Male; Medulla Oblongata

2022
Persistent hiccups in a patient with mild congenital factor V deficiency and COVID-19; clinical and laboratory finding of a rare bleeding disorder.
    International journal of laboratory hematology, 2021, Volume: 43, Issue:2

    Topics: Chlorpromazine; COVID-19; COVID-19 Drug Treatment; Factor V Deficiency; Hematologic Tests; Hemorrhag

2021
Influence of partial and complete evisceration on the action of drugs protecting against lethal hemorrhage.
    Surgery, gynecology & obstetrics, 1954, Volume: 99, Issue:6

    Topics: Abdomen; Chlorpromazine; Hemorrhage; Humans; Protective Agents; Sympatholytics

1954
[Autonomic blockade with atosil and megaphen and its effect on postpneumolysal hemorrhage].
    Beitrage zur Klinik der Tuberkulose und spezifischen Tuberkulose-Forschung, 1955, Volume: 113, Issue:5

    Topics: Anesthesia; Anesthesia, Conduction; Antipsychotic Agents; Chlorpromazine; Collapse Therapy; Hemorrha

1955
Beneficial action of pretreatment with chlorpromazine on survival following graded hemorrhage in the rat.
    Surgery, gynecology & obstetrics, 1955, Volume: 101, Issue:4

    Topics: Animals; Chlorpromazine; Hemorrhage; Rats

1955
[Largactil in therapy of hemorrhagic shock].
    Minerva chirurgica, 1955, Aug-21, Volume: 10, Issue:16

    Topics: Chlorpromazine; Hemorrhage; Humans; Shock; Shock, Hemorrhagic

1955
The effect of chlorpromazine given with reinfusion on the mortality rate from standardized hemorrhagic shock in the rat.
    Canadian journal of biochemistry and physiology, 1956, Volume: 34, Issue:2

    Topics: Animals; Chlorpromazine; Hemorrhage; Rats; Shock; Shock, Hemorrhagic

1956
Effect of chlorpromazine on survival from hemorrhagic shock.
    The American journal of physiology, 1956, Volume: 185, Issue:3

    Topics: Chlorpromazine; Hemorrhage; Shock; Shock, Hemorrhagic

1956
Effect of chlorpromazine on survival from a single massive hemorrhage.
    The American journal of physiology, 1956, Volume: 185, Issue:3

    Topics: Chlorpromazine; Hemorrhage; Humans

1956
Diuresis in hemorrhagic hypotension.
    Surgical forum, 1957, Volume: 7

    Topics: Chlorpromazine; Diuresis; Hemorrhage; Hypotension

1957
[Chronic schizophrenia of the dementia praecox type treated with largactil; terminal epileptic state; anatomical & clinical findings].
    Annales medico-psychologiques, 1958, Volume: 116, Issue:4

    Topics: Chlorpromazine; Epilepsy; Hemorrhage; Humans; Schizophrenia

1958
A comparison of the effects of barbiturates, salicylates, chlorpormazine, 2,4-dinitrophenol and cyanide on the synthesis of glutamine by brain cells in vitro.
    The Australian journal of experimental biology and medical science, 1958, Volume: 36, Issue:1

    Topics: 2,4-Dinitrophenol; Barbiturates; Brain; Chlorpromazine; Cyanides; Dinitrophenols; Glutamine; Hemorrh

1958
[Acetylcholine content in the brain after the administration of chlorpromazine].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1957, Volume: 231, Issue:6

    Topics: Acetylcholine; Brain; Chlorpromazine; Hemorrhage; Humans; Synaptic Transmission

1957
Biochemical and electroencephalographic changes in the brain of rabbits injected with 5-hydroxytryptophan (influence of chlorpromazine premedication).
    The American journal of physiology, 1958, Volume: 194, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Brain; Chlorpromazine; Electroencephalography; Hemorrhage; Lagomorpha;

1958
Hemorrhage from multiple sites associated with chlorpromazine-induced jaundice.
    Journal of the American Medical Association, 1959, Aug-22, Volume: 170, Issue:17

    Topics: Chlorpromazine; Hemorrhage; Humans; Jaundice

1959
SIDE EFFECTS AND COMPLICATIONS OF GASTRIC FREEZING.
    JAMA, 1964, Jun-29, Volume: 188

    Topics: Biomedical Research; Chlorpromazine; Cryosurgery; Duodenal Ulcer; Electrocardiography; Fever; Freezi

1964
Plasma adrenaline and noradrenaline levels during haemorrhage induced after chlorpromazine injection.
    British journal of anaesthesia, 1959, Volume: 31

    Topics: Chlorpromazine; Epinephrine; Hemorrhage; Injections; Norepinephrine; Plasma

1959
Correlation of renal hemodynamics, metabolism, and erythropoietin release in hemorrhagic hypotension and the response to chlorpromazine treatment.
    Investigative urology, 1967, Volume: 4, Issue:6

    Topics: Animals; Chlorpromazine; Dogs; Erythropoietin; Female; Glycolysis; Hemorrhage; Hypotension; Hypotens

1967
Bladder cooling for control of bleeding.
    International surgery, 1967, Volume: 48, Issue:1

    Topics: Aged; Chlorpromazine; Female; Hemorrhage; Humans; Hypothermia, Induced; Male; Meperidine; Middle Age

1967
Venous compensatory mechanisms in acute hypovolemia.
    Surgery, gynecology & obstetrics, 1967, Volume: 125, Issue:3

    Topics: Animals; Blood Circulation; Blood Flow Velocity; Blood Pressure; Blood Volume; Chlorpromazine; Dogs;

1967
The antagonistic effect of chlorpromazine on cadmium toxicity.
    Toxicology and applied pharmacology, 1999, Nov-15, Volume: 161, Issue:1

    Topics: Animals; Cadmium Chloride; Chlorpromazine; Edema; Hemoglobins; Hemorrhage; Liver; Male; Necrosis; Or

1999
Haematological side-effects of drugs.
    The Practitioner, 1976, Volume: 216, Issue:1291

    Topics: Ampicillin; Anemia, Aplastic; Anemia, Hemolytic; Anemia, Megaloblastic; Anti-Inflammatory Agents, No

1976
Evaluation of various hypotensive agents in the control of experimental hemorrhage.
    The Journal of surgical research, 1975, Volume: 18, Issue:1

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Chlorpromazine; Diazoxide; Dogs; Drug Evaluation,

1975
Effect of maternal heroin addiction on 67 liveborn neonates. Withdrawal symptoms, small body size, and small head circumference were frequent findings.
    Clinical pediatrics, 1975, Volume: 14, Issue:8

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Birth Weight; Blood Glucose; Cephalomet

1975
Calmodulin inhibitors protect against cadmium-induced testicular damage in mice.
    Biology of reproduction, 1987, Volume: 37, Issue:1

    Topics: Animals; Cadmium; Cadmium Chloride; Calmodulin; Chlorpromazine; Edema; Endothelium, Vascular; Hemorr

1987
[Phospholipase A2 inhibitors in hemorrhagic-necrotizing pancreatitis. Animal experiment evaluation of a new treatment concept].
    Zeitschrift fur Gastroenterologie, 1985, Volume: 23, Issue:12

    Topics: Acute Disease; Animals; Chlorpromazine; Dogs; Edetic Acid; Female; Gabexate; Guanidines; Hemodynamic

1985
Decreased adrenal sensitivity to ACTH in the vasopressin-deficient (Brattleboro) rat.
    Neuroendocrinology, 1974, Volume: 14, Issue:5

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Chlorpromazine; Corticotropin-Releasing Hormon

1974
Thrombocytopenia and bleeding complications in severe cases of meningococcal infection treated with heparin, dextran 70 and chlorpromazine.
    Scandinavian journal of infectious diseases, 1972, Volume: 4, Issue:3

    Topics: Adolescent; Adult; Aspirin; Blood Platelet Disorders; Cephalothin; Chlorpromazine; Dexamethasone; De

1972
Effects of dexamethasone and chlorpromazine on skeletal muscle surface hydrogen ion concentration during cardiopulmonary bypass: experimental and clinical results.
    Annals of surgery, 1972, Volume: 176, Issue:6

    Topics: Animals; Blood; Blood Flow Velocity; Carbon Dioxide; Child; Child, Preschool; Chlorpromazine; Dexame

1972
The electro-encephalogram in patients with post-traumatic fat embolism.
    Injury, 1972, Volume: 4, Issue:1

    Topics: Adult; Aged; Blood Transfusion; Chlorpromazine; Dextrans; Dyspnea; Electroencephalography; Embolism,

1972
[Autoperfusion of a heart-lung-kidney device. I. General enzymatic observations during perfusion].
    Acta chirurgica Academiae Scientiarum Hungaricae, 1973, Volume: 14, Issue:3

    Topics: Adenosine Triphosphate; Alanine Transaminase; Animals; Aspartate Aminotransferases; Automation; Bloo

1973
Growth hormone secretion in the unanesthetized rhesus monkey in response to noxious stimuli.
    Endocrinology, 1967, Volume: 80, Issue:1

    Topics: Animals; Cardiac Catheterization; Chlorpromazine; Epinephrine; Growth Hormone; Haplorhini; Hemorrhag

1967
Observations on the secretion of growth hormone, and its blockade, in the rhesus monkey.
    Annals of the New York Academy of Sciences, 1968, Feb-05, Volume: 148, Issue:2

    Topics: Animals; Arousal; Blood Glucose; Chlorpromazine; Fatty Acids, Nonesterified; Growth Hormone; Haplorh

1968
Spontaneous hemorrhage in anticoagulant-treated rats when subjected to excitant or depressant drugs.
    Thrombosis et diathesis haemorrhagica, 1967, May-31, Volume: 17, Issue:3-4

    Topics: Animals; Anticoagulants; Barbiturates; Blood Coagulation; Chlordiazepoxide; Chlorpromazine; Depressi

1967
The effects of drugs on the release of vasopressin.
    British journal of pharmacology and chemotherapy, 1968, Volume: 33, Issue:2

    Topics: Animals; Calcium Chloride; Chlorpheniramine; Chlorpromazine; Electric Stimulation; Epinephrine; Hemo

1968
Renal response to chlorpromazine in hemorrhagic hypotension: hemodynamic and metabolic changes and adrenolytic effect in dogs.
    Annals of surgery, 1966, Volume: 164, Issue:5

    Topics: Animals; Blood Pressure; Chlorpromazine; Dogs; Hemodynamics; Hemorrhage; Hypotension; In Vitro Techn

1966