chlorpromazine has been researched along with Bilirubinemia in 8 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Intrahepatic cholestasis associated with hyperbilirubinemia was induced by the simultaneous administration of ethynyl estradiol (EE) and chlorpromazine hydrochloride (CPZ) for 7 days to female Sprague-Dawley rats." | 7.66 | Intrahepatic cholestasis and hyperbilirubinemia in ethynyl estradiol and chlorpromazine-treated rats. ( Obata, T, 1983) |
| " In addition, characterization of the UGT1A locus and genetic studies directed at understanding the role of bilirubin glucuronidation and the biochemical basis of the clinical symptoms found in unconjugated hyperbilirubinemia have uncovered the structural gene polymorphisms associated with Crigler-Najjar's and Gilbert's syndrome." | 4.80 | Human UDP-glucuronosyltransferases: metabolism, expression, and disease. ( Strassburg, CP; Tukey, RH, 2000) |
| "Intrahepatic cholestasis associated with hyperbilirubinemia was induced by the simultaneous administration of ethynyl estradiol (EE) and chlorpromazine hydrochloride (CPZ) for 7 days to female Sprague-Dawley rats." | 3.66 | Intrahepatic cholestasis and hyperbilirubinemia in ethynyl estradiol and chlorpromazine-treated rats. ( Obata, T, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (87.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tukey, RH | 1 |
| Strassburg, CP | 1 |
| NORREDAM, K | 1 |
| MCDONALD, R | 1 |
| SHAW, M | 1 |
| CRAIG, C | 1 |
| BELL, JL | 1 |
| WILLIAMS, R | 1 |
| Nichols, MM | 1 |
| Obata, T | 1 |
| Roberts, RJ | 2 |
| Plaa, GL | 2 |
1 review available for chlorpromazine and Bilirubinemia
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; | 2000 |
7 other studies available for chlorpromazine and Bilirubinemia
| Article | Year |
|---|---|
CHLORPROMAZINE JAUNDICE OF LONG DURATION.
Topics: Alanine Transaminase; Alkaline Phosphatase; Aspartic Acid; Biopsy; Bone Diseases; Chlorpromazine; Cl | 1963 |
EFFECT OF PHENOTHIAZINES AND ANALGESICS, GIVEN DURING LABOUR, ON NEONATAL SERUM BILIRUBIN.
Topics: Adjuvants, Anesthesia; Analgesics; Anesthesia; Anesthesia, Obstetrical; Bilirubin; Blood Chemical An | 1964 |
THE VALUE OF JIRGL'S FLOCCULATION TEST IN THE DIAGNOSIS OF JAUNDICE.
Topics: Alkaline Phosphatase; Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury; Chlorpromaz | 1964 |
Acute alcohol withdrawal syndrome in a newborn.
Topics: Adult; Alcoholism; Chlorpromazine; Exchange Transfusion, Whole Blood; Female; Glucose; Humans; Hyper | 1967 |
Intrahepatic cholestasis and hyperbilirubinemia in ethynyl estradiol and chlorpromazine-treated rats.
Topics: Animals; Chlorpromazine; Cholestasis, Intrahepatic; Disease Models, Animal; Ethinyl Estradiol; Femal | 1983 |
Studies on bilirubin production and excretion in mice and rats treated with phenobarbital, chlorpromazine, norethandrolone, acetohexamide or enovid.
Topics: Acetohexamide; Animals; Bile; Bile Ducts; Bilirubin; Carbon Isotopes; Chlorpromazine; Hyperbilirubin | 1969 |
Potentiation and inhibition of alpha-naphthylisothiocyanate-induced hyperbilirubinemia and cholestasis.
Topics: Animals; Chlorpromazine; Cholestasis; Dactinomycin; Ethionine; Hyperbilirubinemia; In Vitro Techniqu | 1965 |