chlorpromazine has been researched along with Bile Duct Obstruction, Intrahepatic in 8 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Intrahepatic cholestasis associated with hyperbilirubinemia was induced by the simultaneous administration of ethynyl estradiol (EE) and chlorpromazine hydrochloride (CPZ) for 7 days to female Sprague-Dawley rats." | 7.66 | Intrahepatic cholestasis and hyperbilirubinemia in ethynyl estradiol and chlorpromazine-treated rats. ( Obata, T, 1983) |
| " 18 days after the medication of chlorprothixeni hydrochloridum and chlorpromazine treatment in the 33rd week of pregnancy." | 3.71 | Chlorpromazine-induced cholestatic liver disease with ductopenia. ( Boudová, L; Chlumská, A; Curík, R; Klvana, P; Mukensnabl, P, 2001) |
| "Intrahepatic cholestasis associated with hyperbilirubinemia was induced by the simultaneous administration of ethynyl estradiol (EE) and chlorpromazine hydrochloride (CPZ) for 7 days to female Sprague-Dawley rats." | 3.66 | Intrahepatic cholestasis and hyperbilirubinemia in ethynyl estradiol and chlorpromazine-treated rats. ( Obata, T, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (87.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| SPELLBERG, MA | 1 |
| Obata, T | 1 |
| Paumgartner, G | 1 |
| Paumgartner, D | 1 |
| Plaa, GL | 1 |
| Hewitt, WR | 1 |
| Tavoloni, N | 1 |
| Boyer, JL | 1 |
| Chlumská, A | 1 |
| Curík, R | 1 |
| Boudová, L | 1 |
| Mukensnabl, P | 1 |
| Klvana, P | 1 |
| Kondoh, M | 1 |
| Aoki, Y | 1 |
| Ogawa, Z | 1 |
| Hata, Y | 1 |
| Suzuki, H | 1 |
| Itoh, H | 1 |
| Jung, W | 1 |
| Gebhardt, R | 1 |
| Robenek, H | 1 |
1 review available for chlorpromazine and Bile Duct Obstruction, Intrahepatic
| Article | Year |
|---|---|
Biotransformation products and cholestasis.
Topics: 1-Naphthylisothiocyanate; Animals; Antidepressive Agents, Tricyclic; Bile Acids and Salts; Biotransf | 1982 |
7 other studies available for chlorpromazine and Bile Duct Obstruction, Intrahepatic
| Article | Year |
|---|---|
INTRAHEPATIC CHOLESTASIS VS. POSTHEPATIC JAUNDICE: METHODS OF DIAGNOSIS, WITH A NOTE ON HYPERCHOLESTEREMIC XANTHOMATOSIS IN A PATIENT WITH CHLORPROMAZINE CHOLESTASIS.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Alkaline Phosphatase; Androgens; Anti-Bacteria | 1964 |
Intrahepatic cholestasis and hyperbilirubinemia in ethynyl estradiol and chlorpromazine-treated rats.
Topics: Animals; Chlorpromazine; Cholestasis, Intrahepatic; Disease Models, Animal; Ethinyl Estradiol; Femal | 1983 |
[Damage to liver and biliary tracts by long-term drug therapy (author's transl)].
Topics: Chemical and Drug Induced Liver Injury; Chlorpromazine; Cholestasis, Intrahepatic; Dose-Response Rel | 1980 |
Relationship between hepatic metabolism of chlorpromazine and cholestatic effects in the isolated perfused rat liver.
Topics: Animals; Bile Acids and Salts; Biotransformation; Chlorpromazine; Cholestasis, Intrahepatic; Enzyme | 1980 |
Chlorpromazine-induced cholestatic liver disease with ductopenia.
Topics: Adult; Bile Ducts, Intrahepatic; Chlorpromazine; Cholestasis, Intrahepatic; Female; Humans; Infant, | 2001 |
Effect of chlorpromazine on transmigration of mitochondrial aspartate aminotransferase in rat liver.
Topics: Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Chlorpromazine; Choles | 1989 |
Primary culture of rat hepatocytes as a model system of canalicular development, biliary secretion, and intrahepatic cholestasis. V. Disturbance of the cellular membrane and bile canalicular ultrastructure induced by chlorpromazine.
Topics: Animals; Bile; Bile Ducts, Intrahepatic; Cell Membrane; Cell Survival; Cells, Cultured; Chlorpromazi | 1985 |