chlorpromazine has been researched along with Benign Neoplasms, Brain in 10 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "On these bases, and assisted by the information on the well-established chlorpromazine toxicity and dosage in humans, we designed a Phase II clinical trial involving the combination of chlorpromazine with the standard treatment, temozolomide, in the adjuvant phase of the therapeutic protocol." | 5.56 | Repurposing chlorpromazine in the treatment of glioblastoma multiforme: analysis of literature and forthcoming steps. ( Abbruzzese, C; Matteoni, S; Paggi, MG; Persico, M; Villani, V, 2020) |
| "Chlorpromazine is a United States Food and Drug Administration-approved phenothiazine widely used as a psychotropic in clinical practice." | 5.46 | Repositioning chlorpromazine for treating chemoresistant glioma through the inhibition of cytochrome c oxidase bearing the COX4-1 regulatory subunit. ( Griguer, CE; Langford, C; Oliva, CR; Suto, MJ; Zhang, W, 2017) |
| "The effects of chlorpromazine and related compounds upon soluble and particulate Ins(1,4,5)P3-5-phosphatase were investigated in rat GH3 pituitary and in human IMR-32 neuroblastoma cells." | 3.68 | Inhibition of inositol-1,4,5-trisphosphate-5-phosphatase by chlorpromazine and related compounds. ( Brännström, G; Fowler, CJ, 1992) |
| "On these bases, and assisted by the information on the well-established chlorpromazine toxicity and dosage in humans, we designed a Phase II clinical trial involving the combination of chlorpromazine with the standard treatment, temozolomide, in the adjuvant phase of the therapeutic protocol." | 1.56 | Repurposing chlorpromazine in the treatment of glioblastoma multiforme: analysis of literature and forthcoming steps. ( Abbruzzese, C; Matteoni, S; Paggi, MG; Persico, M; Villani, V, 2020) |
| "Chlorpromazine is a United States Food and Drug Administration-approved phenothiazine widely used as a psychotropic in clinical practice." | 1.46 | Repositioning chlorpromazine for treating chemoresistant glioma through the inhibition of cytochrome c oxidase bearing the COX4-1 regulatory subunit. ( Griguer, CE; Langford, C; Oliva, CR; Suto, MJ; Zhang, W, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (40.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 2 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abbruzzese, C | 1 |
| Matteoni, S | 1 |
| Persico, M | 1 |
| Villani, V | 1 |
| Paggi, MG | 1 |
| Jeng, F | 1 |
| Reynolds, A | 1 |
| Oliva, CR | 1 |
| Zhang, W | 1 |
| Langford, C | 1 |
| Suto, MJ | 1 |
| Griguer, CE | 1 |
| SOURS, JA | 1 |
| Nguyen, JD | 1 |
| Dunleavy, K | 1 |
| Carrasquillo, JA | 1 |
| Chen, CC | 1 |
| Aas, AT | 1 |
| Brun, A | 1 |
| Pero, RW | 1 |
| Salford, LG | 1 |
| Joasson, JM | 1 |
| Saugier, B | 1 |
| Brune, J | 1 |
| Galy, P | 1 |
| Borshchagovskiĭ, ML | 1 |
| Dubikaitis, IuV | 1 |
| Fowler, CJ | 1 |
| Brännström, G | 1 |
| Costin, G | 1 |
| Fefferman, RA | 1 |
| Kogut, MD | 1 |
10 other studies available for chlorpromazine and Benign Neoplasms, Brain
| Article | Year |
|---|---|
Repurposing chlorpromazine in the treatment of glioblastoma multiforme: analysis of literature and forthcoming steps.
Topics: Brain Neoplasms; Chlorpromazine; Drug Repositioning; Female; Glioblastoma; Humans; Male | 2020 |
Retrobulbar chlorpromazine injection in a child with gliosarcoma invasion into the orbits.
Topics: Antipsychotic Agents; Blindness; Brain Neoplasms; Chemoradiotherapy; Child; Chlorpromazine; Eye Pain | 2020 |
Repositioning chlorpromazine for treating chemoresistant glioma through the inhibition of cytochrome c oxidase bearing the COX4-1 regulatory subunit.
Topics: Animals; Antineoplastic Agents, Alkylating; Antipsychotic Agents; Brain Neoplasms; Cattle; Cell Line | 2017 |
NEUROPSYCHIATRIC FINDINGS IN INTERNAL CAROTID ARTERY OCCLUSIVE DISEASE WITH CEREBROVASCULAR DAMAGE. REPORT OF NINE CASES AND REVIEW OF THE LITERATURE.
Topics: Anticoagulants; Brain Neoplasms; Carotid Artery Diseases; Carotid Artery Thrombosis; Carotid Artery, | 1964 |
F-18 fluorodeoxyglucose positron emission tomographic imaging in a patient with persistent hiccups.
Topics: Baclofen; Brain; Brain Neoplasms; Chlorpromazine; Diagnosis, Differential; Fluorodeoxyglucose F18; H | 2004 |
Chlorpromazine in combination with nitrosourea inhibits experimental glioma growth.
Topics: Animals; Body Weight; Brain Neoplasms; Calmodulin; Carmustine; Cell Division; Chlorpromazine; Drug S | 1994 |
[Small-celled lung cancer. Results of therapy].
Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Chlorpromazine; Doxorubicin; Drug Therapy, Comb | 1979 |
[Clinico-electroencephalographic characteristics of the condition of brain stem systems following surgical and non-surgical brain injury].
Topics: Adult; Amphetamine; Anesthesia, General; Autonomic Nervous System; Brain Injuries; Brain Neoplasms; | 1976 |
Inhibition of inositol-1,4,5-trisphosphate-5-phosphatase by chlorpromazine and related compounds.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain Neoplasms; Cells, Cultured; Chlorpromazine; Fluphen | 1992 |
Hypothalamic gigantism.
Topics: Arginine; Brain Neoplasms; Child, Preschool; Chlorpromazine; Cobalt Isotopes; Dexamethasone; Giganti | 1973 |